| Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis (NCT05020028) | NYU Langone Health | 2022-06-22 |
| A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy (NCT05455684) | Janssen Research & Development, LLC | 2022-06-22 |
| Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk (NCT05098704) | University Hospital, Bordeaux | 2022-06-22 |
| A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy (NCT05126758) | Capricor Inc. | 2022-06-22 |
| Evaluation of Spironolactone Efficacy in Patient with Rheumatoid Arthritis (RA) (NCT05092984) | University Hospital, Strasbourg, France | 2022-06-22 |
| A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease (NCT05218655) | PTC Therapeutics | 2022-06-22 |
| Efficacy and Safety of Nitazoxanide 600 mg BID Versus Placebo for the Treatment of Hospitalized Patients With COVID-19 (NCT04423861) | Azidus Brasil | 2022-06-22 |
| Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patients (NCT05397600) | Laboratoires Thea | 2022-06-22 |
| Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly (NCT06040489) | University of Brasilia | 2022-06-22 |
| Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea (NCT05412004) | Eli Lilly and Company | 2022-06-21 |
| Ventral Capsulotomy for Intractable OCD (NCT05659082) | Butler Hospital | 2022-06-21 |
| A Study to Evaluate the Safety and Immunogenicity of the mRNA COVID-19 Vaccines in Healthy Children Between 6 Months to Less Than 6 Years of Age (NCT05436834) | ModernaTX, Inc. | 2022-06-21 |
| Utidelone Versus Docetaxel in HER2-negative Locally Advanced or Metastatic Breast Cancer (NCT05430399) | Sun Yat-sen University | 2022-06-21 |
| A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential Hypertension (NCT07116863) | Kyungdong Pharmaceutical Co., Ltd. | 2022-06-21 |
| Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies (NCT05316701) | Orca Biosystems, Inc. | 2022-06-21 |
| The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI Ichthyosis (NCT05295732) | LEO Pharma | 2022-06-21 |
| Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age (NCT05422222) | Vertex Pharmaceuticals Incorporated | 2022-06-21 |
| A Study of AK104/Placebo Combined With Chemoradiotherapy For The Treatment of Locally Advanced Cervical Cancer (NCT05235516) | Akeso | 2022-06-21 |
| A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1) (NCT05306574) | Vor Biopharma | 2022-06-20 |
| Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients (NCT05004675) | LIB Therapeutics LLC | 2022-06-20 |
| MDT-bridged Radical Therapy After Aumolertinib With MRD-guided Maintenance in EGFRm+ Unresectable Stage III NSCLC (APPROACH) (NCT04841811) | Guangdong Association of Clinical Trials | 2022-06-20 |
| Antibiotic Loaded Cement After TKA (NCT05429671) | Rothman Institute Orthopaedics | 2022-06-20 |
| Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas (NCT05130866) | Recursion Pharmaceuticals Inc. | 2022-06-20 |
| Use of Colchicine to Decrease Atrial Fibrillation Recurrence After Ablation (NCT05459974) | Stony Brook University | 2022-06-20 |
| Nebulised Heparin in Patients With COVID-19 Pneumonia (NCT05255848) | Lady Reading Hospital, Pakistan | 2022-06-20 |
| Prevention of Rabies With Four Doses of Rabies Vaccine (NCT05545371) | Changchun Zhuoyi Biological Co., Ltd | 2022-06-18 |
| Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria (NCT05270837) | BioMarin Pharmaceutical | 2022-06-17 |
| Suaahara Impact Evaluation: End-line Survey (NCT05448287) | University of South Carolina | 2022-06-17 |
| A Study to Evaluate the Efficacy and Safety of HLX14 vs. Denosumab Prolia® in Postmenopausal Women With Osteoporosis at High Risk of Fracture (NCT05352516) | Shanghai Henlius Biotech | 2022-06-17 |
| Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus (NCT04600167) | Dr. Nyanda Elias Ntinginya | 2022-06-17 |
| A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients with Chronic Kidney Disease-Associated Pruritus (NCT05135390) | Haisco Pharmaceutical Group Co., Ltd. | 2022-06-17 |
| A Study to Compare T-Guard vs Ruxolitinib for Treatment of Steroid-Refractory Acute Graft-vs-Host Disease (BMT CTN 2002) (NCT04934670) | Xenikos | 2022-06-16 |
| Efficacy and Safety of Losmapimod in Treating Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) (REACH) (NCT05397470) | Fulcrum Therapeutics | 2022-06-16 |
| Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy)) (NCT05135091) | Neurona Therapeutics | 2022-06-16 |
| Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease (NCT04523727) | Keryx Biopharmaceuticals | 2022-06-16 |
| Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT (NCT05429632) | Priothera SAS | 2022-06-16 |
| Evaluation of Avatrombopag for the Treatment of Thrombocytopenia in Japanese Adults With Chronic ITP (NCT05369208) | Sobi, Inc. | 2022-06-15 |
| Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer (NCT05132075) | Novartis Pharmaceuticals | 2022-06-15 |
| Statin Impact on Hepatic Decompensation (NCT05563389) | Tanta University | 2022-06-15 |
| Effects of Tralokinumab in the Skin: an Immunologic and Molecular Investigation (NCT05378698) | University of Zurich | 2022-06-15 |
| NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection (NCT04452565) | Biomed Industries, Inc. | 2022-06-15 |
| Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount) (NCT05336786) | Thomas Jefferson University | 2022-06-15 |
| Allopurinol and Quality of Life in Liver Cirrhosis (NCT05828836) | Tanta University | 2022-06-15 |
| Efficacy of 1% Metformin Gel Mixed With PRF in Augmenting Narrow Ridge (NCT05418452) | Al-Azhar University | 2022-06-15 |
| A Trial of Hepatic Arterial Infusion Combined With Apatinib and Camrelizumab Versus Apatinib and Camrelizumab for C-staged Hepatocellular Carcinoma in BCLC Classification (NCT05313282) | Sun Yat-sen University | 2022-06-15 |
| Effectiveness and Safety of TENS Therapy for Premature Ejaculation (NCT06425224) | Boston Medical Group | 2022-06-15 |
| A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema (NCT05259722) | LEO Pharma | 2022-06-15 |
| Manual Therapy in Addition to Pulmonary Rehabilitation in Moderate Chronic Obstructive Pulmonary Disease. (NCT04386590) | Canandaigua VA Medical Center | 2022-06-15 |
| Allopurinol to Prevent Cirrhosis Related Morbidities (NCT05545670) | Tanta University | 2022-06-15 |
| Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study) (NCT05238116) | Pulmocide Ltd | 2022-06-14 |
| Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS (NCT05267821) | Nationwide Children's Hospital | 2022-06-14 |
| A Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial Carcinoma (NCT05302284) | RemeGen Co., Ltd. | 2022-06-14 |
| A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)-China Extension Study (NCT05600309) | Merck Sharp & Dohme LLC | 2022-06-14 |
| GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS (NCT05266001) | Nationwide Children's Hospital | 2022-06-14 |
| mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression (NCT05186272) | Kaiser Permanente | 2022-06-14 |
| Pharmacokinetics and Safety of MB-102 (Relmapirazin) and the MediBeacon Transdermal GFR Measurement System in Evaluation of Kidney Function in Normal and Renal Compromised Subjects (NCT05425719) | MediBeacon | 2022-06-14 |
| A Study of Atezolizumab in High PD-L1 Expression, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NCT05047250) | Hoffmann-La Roche | 2022-06-14 |
| Ivabradine for Prevention of Myocardial Injury After Noncardiac Surgery Trial (PREVENT-MINS) (NCT05279651) | Jagiellonian University | 2022-06-13 |
| Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia (NCT05316493) | Xiaojun Chen | 2022-06-13 |
| PK of TAF and TDF for PrEP in Pregnant and Postpartum Women (NCT04937881) | University of California, Los Angeles | 2022-06-13 |
| Immunogenicity and Safety Study of SCB-2019 Vaccine as a Booster to COVID-19 Vaccine in Adults (NCT05188677) | Clover Biopharmaceuticals AUS Pty | 2022-06-13 |
| Study of Efficacy and Safety of GR1501 in Patients with Radiographic Axial Spondyloarthritis (NCT05881785) | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 2022-06-13 |
| Transplacental Aspirin Therapy for Early Onset Fetal Growth Restriction (NCT04557475) | Johns Hopkins University | 2022-06-11 |
| An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus (NCT05352919) | Biogen | 2022-06-10 |
| SKB264 Injection vs Investigator Selected Regimens to Treat Locally Advanced, Recurrent or Metastatic Triple-negative Breast Cancer (NCT05347134) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2022-06-10 |
| Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma (NCT05211232) | Sun Yat-sen University | 2022-06-10 |
| Intermediate Risk Cervical Cancer: Radical Surgery +/- Adjuvant Radiotherapy (NCT04989647) | The Central and Eastern European Gynecologic Oncology Group | 2022-06-10 |
| An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma (NCT05022901) | Delcath Systems Inc. | 2022-06-10 |
| TACE With Dicycloplatin(TP21) in Unresectable HCC (NCT05472896) | Gao-jun Teng | 2022-06-09 |
| Study of SMT-NK Inj. Plus Pembrolizumab vs Pembrolizumab Monotherapy in Patients With Advanced Biliary Tract Cancer (NCT05429697) | SMT bio Co., Ltd. | 2022-06-09 |
| Study of BEBT-209 in Combination With Fulvestrant Versus Placebo in Combination With Fulvestrant in Patients With HR+/HER2- Locally Advanced or Metastatic Breast Cancer Who Have Progressed After Prior Endocrine Therapy (NCT06998108) | BeBetter Med Inc | 2022-06-09 |
| A Phase 2/3 Study of Efgartigimod PH20 SC in Adult Participants With Bullous Pemphigoid (NCT05267600) | argenx | 2022-06-09 |
| Study for Efficacy and Safety Assessment of the Drug RADAMIN®VIRO for COVID-19 Postexposure Prophylaxis (NCT05722691) | Promomed, LLC | 2022-06-09 |
| Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea (NCT06690723) | University Malaysia Sarawak | 2022-06-08 |
| A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period (NCT05144256) | Agios Pharmaceuticals, Inc. | 2022-06-08 |
| Randomized, Single-blinded, Multicenter Trial Comparing the Immune Response to a 2nd Booster Dose of COVID-19 mRNA Vaccine (Pfizer-BioNTech) or Sanofi /GSK B.1.351 Adjuvanted Vaccine in Adults (NCT05405283) | Assistance Publique - Hôpitaux de Paris | 2022-06-08 |
| Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO) (NCT05382728) | TYK Medicines, Inc | 2022-06-08 |
| A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients for Postoperative Pain Treatment (NCT05390905) | Haisco Pharmaceutical Group Co., Ltd. | 2022-06-08 |
| DAPAgliflozin for Renal Protection in Heart Transplant Recipients (NCT05321706) | Oslo University Hospital | 2022-06-08 |
| Studying Conditioning Regimen In Pediatric Transplantation - AML , SCRIPT-AML (NCT05477589) | Vastra Gotaland Region | 2022-06-07 |
| Efficacy and Safety of Pirfenidone Capsules in the Treatment of Pneumoconiosis (NCT05288179) | Beijing Continent Pharmaceutical Co, Ltd. | 2022-06-07 |
| THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS) (NCT05033314) | University Health Network, Toronto | 2022-06-07 |
| KL-A167 Injection Combined With Cisplatin and Gemcitabine vs Placebo Combined With Cisplatin and Gemcitabine in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma (NCT05294172) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2022-06-07 |
| Immuno-bridging Study of COVID-19 Protein Subunit Recombinant Vaccine (NCT05433285) | PT Bio Farma | 2022-06-07 |
| Thoracic Intervertebral Foramen Block (NCT05603442) | San Salvatore Hospital of L'Aquila | 2022-06-07 |
| Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients (NCT05310916) | Nidae Alaa | 2022-06-06 |
| A Study of mRNA-1010 Seasonal Influenza Vaccine in Adults (NCT05415462) | ModernaTX, Inc. | 2022-06-06 |
| Ferric Derisomaltose (Iron Isomaltoside) Versus Iron Sucrose for Treatment of Iron Deficiency in Pregnancy (NCT05251493) | Saskatchewan Health Authority - Regina Area | 2022-06-06 |
| Understanding How Methadone Treatment During Surgery Affects Pain Levels and the Need for Pain Medications After Surgery (NCT05417100) | Memorial Sloan Kettering Cancer Center | 2022-06-06 |
| A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period (NCT05175105) | Agios Pharmaceuticals, Inc. | 2022-06-06 |
| Effect of Mouthwash in Reducing the Symptoms Associated With Flu and Cold Viruses (NCT06479226) | Colgate Palmolive | 2022-06-05 |
| Pharmacokinetics, Safety, Efficacy and Acceptability of Daclatasvir Plus Sofosbuvir in HCV-infected Children (NCT05854511) | Ain Shams University | 2022-06-05 |
| Canagliflozin in Patients With Acute Decompansted Heart Failure (NCT05364190) | October 6 University | 2022-06-04 |
| A Phase III Clinical Trial of a 11-valent Recombinant Human Papillomavirus Vaccine (Hansenulapolymorpha) in Chinese Women Aged 9-45 Years (NCT05262010) | National Vaccine and Serum Institute, China | 2022-06-04 |
| Cyclosporine 0.1% / Loteprednol 0.2% Effect on Anterior Segment Normalization (NCT05322148) | Research Insight LLC | 2022-06-03 |
| Real World Evaluation of the Effectiveness of AZD7442 for Prevention of SARS-CoV-2 (NCT05438498) | MediMergent, LLC | 2022-06-03 |
| STRIDES - a Clinical Research Study of an Investigational New Drug to Treat Spinocerebellar Ataxia (NCT05490563) | Seelos Therapeutics, Inc. | 2022-06-03 |
| A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (NCT05362058) | Eli Lilly and Company | 2022-06-03 |
| A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor (NCT05366751) | Sage Therapeutics | 2022-06-03 |
| Olanzapine for the Treatment of Chronic Nausea and/or Vomiting in Patients With Advanced Cancer (NCT05403580) | Mayo Clinic | 2022-06-03 |