| Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study (NCT05092958) | National Cancer Institute (NCI) | 2022-06-03 |
| A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy (NCT05115110) | Hoffmann-La Roche | 2022-06-02 |
| Pilot Study to Investigate the Effect of Teduglutide on Temporary Ileostomy Function and Complications (NCT03953170) | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 2022-06-02 |
| Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial) (NCT05321875) | Cristina Avendaño Solá | 2022-06-02 |
| A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease (NCT05310071) | Biogen | 2022-06-02 |
| Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization (NCT05478551) | Henry Ford Health System | 2022-06-01 |
| Nebulised 3% Hypertonic Saline in Infants With Acute Bronchiolitis (NCT06558461) | Can Tho University of Medicine and Pharmacy | 2022-06-01 |
| Use of Baricitenib to Maintain of Remission (NCT05686746) | Assiut University | 2022-06-01 |
| COMPARING TWO PROTOCOLS FOR FINAL OOCYTE MATURATION IN POOR RESPONDERS UNDERGOING GnRH-ANTAGONIST ICSI CYCLES (NCT05397795) | Alexandria University | 2022-06-01 |
| Dressing Impregnated With Chlorhexidine and Vancomycin for the Prophylaxis of Central Venous Catheter-related Infections - a Randomized Trial (NCT07001527) | Hospital Universitario Evangelico de Curitiba | 2022-06-01 |
| L-DEP/DEP Regimen and PD-1 Antibody as a Treatment for Relapse/Refractory EBV-HLH (NCT05315336) | Beijing Friendship Hospital | 2022-06-01 |
| DISE in Pediatric Sleep Disordered Breathing (NCT06756971) | University of Iowa | 2022-06-01 |
| A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes (NCT05280496) | Tufts Medical Center | 2022-06-01 |
| Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis (NCT06466538) | Mansoura University | 2022-06-01 |
| Metformin to Prevent Preterm Birth in Twin Pregnancy (NCT05412056) | The University of Hong Kong | 2022-06-01 |
| Genotype-guided Treatment in DLBCL (NCT05351346) | Ruijin Hospital | 2022-06-01 |
| A Study of MSDC-0602K to Assess Glycemic Control and Cardiovascular Outcomes in Patients With Pre-T2D or T2D and NAFLD/NASH (NCT03970031) | Cirius Therapeutics, Inc. | 2022-06-01 |
| Study of Atomoxetine in the Prevention of Vasovagal Syncope (NCT05159687) | University of Calgary | 2022-06-01 |
| Effect of Palonosetron, Ondansetron and Dexamethasone in the Prevention of Postoperative Nausea and Vomiting (NCT05439798) | Selcuk University | 2022-06-01 |
| Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis (NCT06153706) | Yasmeen Khaled | 2022-06-01 |
| Treatment of Non-severe Covid-19 Outpatients With Xagrotin, Phase 3 (NCT05222425) | Biomad AS | 2022-06-01 |
| TARGETING DUAL PATHWAYS IN REFRACTORY COCCYDYNIA (NCT07060313) | Istanbul University | 2022-06-01 |
| Whole-Body Electromyostimulation and Knee Osteoarthritis (NCT05672264) | University of Erlangen-Nürnberg Medical School | 2022-06-01 |
| Immunogenicity and Safety of Booster Immunization of COVID-19 Vaccine (Vero Cell), Inactivated (Omicron Variant) in Healthy People Aged 18 Years and Above (NCT05381350) | Sinovac Research and Development Co., Ltd. | 2022-06-01 |
| Efficiency of Use of Baracetinib in Treatment of Lupus Nephritis (NCT05432531) | Assiut University | 2022-06-01 |
| Ruxolitinib and Methylprednisolone as a First-line Treatment for Macrophage Activation Syndrome (NCT05137496) | Beijing Friendship Hospital | 2022-06-01 |
| Sertraline Versus Escitalopram in South Asian Participants With Moderate to Severe Major Depressive Disorder (NCT05950061) | KRL Hospital, Islamabad | 2022-06-01 |
| Vizol S Lipid Balance Efficacy and Safety Study in Patients With Dry Eye (NCT06323395) | Jadran Galenski laboratorij d.d. | 2022-06-01 |
| Efficacy of EGF-loaded Self Healing Gel in Treatment of Oral Mucositis (NCT04995354) | Cairo University | 2022-06-01 |
| Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCC (NCT05213312) | Shanghai Zhongshan Hospital | 2022-06-01 |
| Hyperbaric Oxygen Therapy for Pyoderma Gangrenosum (NCT05343754) | Erasmus Medical Center | 2022-06-01 |
| Pirfenidone to Prevent Fibrosis in Ards. (NCT05075161) | Università Vita-Salute San Raffaele | 2022-06-01 |
| The BeLimumab Antiphospholipid Syndrome Trial (BLAST) (NCT05020782) | University of Turin, Italy | 2022-06-01 |
| Clopidogrel Versus Cilostazol in Ischemic Stroke (NCT06242132) | Kafrelsheikh University | 2022-06-01 |
| Early High-Dose Vitamin D and Residual β-Cell Function in Pediatric Type 1 Diabetes (NCT05270343) | Shanghai Jiao Tong University School of Medicine | 2022-06-01 |
| Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC (NCT05495425) | Nobelpharma | 2022-06-01 |
| A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec (NCT05352815) | Novo Nordisk A/S | 2022-06-01 |
| Topical Insulin Drops for the Treatment of Neurotrophic Keratopathy. (NCT05321251) | University of Alberta | 2022-06-01 |
| Ceftazidime-Avibactam Use in Critically Ill Patients With Carbapenem-Resistant Enterobacteriaceae Infections (NCT05258851) | King Faisal Specialist Hospital & Research Center | 2022-06-01 |
| Effects of Cannabidiol (CBD) Versus Placebo as an Adjunct to Treatment in Early Psychosis (NCT04411225) | University of California, San Diego | 2022-06-01 |
| The Lacosamide's Effect on Calcitonin Gene-related Peptide in Migraine Patients (NCT05632133) | Kafrelsheikh University | 2022-06-01 |
| A Pilot Study of Antioxidant Therapy in Obstructive Sleep Apnea Patients (NCT05009901) | University of British Columbia | 2022-06-01 |
| Lacosamide Versus Propranolol in Migraine (NCT05851781) | Kafrelsheikh University | 2022-06-01 |
| Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches (NCT05306899) | University Health Network, Toronto | 2022-06-01 |
| Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF) (NCT05174052) | University of Oklahoma | 2022-06-01 |
| Budesonide Multimatrix(MMX) Versus Prednisolone in Management of Mild to Moderate Ulcerative Colitis (NCT05341401) | Assiut University | 2022-06-01 |
| Empagliflozin in Hypertrophic Cardiomyopathy (NCT05182658) | National Institute of Cardiology, Warsaw, Poland | 2022-06-01 |
| The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia (NCT05287321) | Yoo-min Kim | 2022-05-31 |
| A Phase III Clinical Study of Minodronate Tablets in Postmenopausal Women With Osteoporosis (NCT05305183) | Shandong New Time Pharmaceutical Co., LTD | 2022-05-31 |
| Silodosin vs Tamsulosin as MET (NCT05570084) | Princess Margaret Hospital, Hong Kong | 2022-05-31 |
| A Long-term Administration Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With Schizophrenia (NCT05326347) | Otsuka Pharmaceutical Co., Ltd. | 2022-05-31 |
| A Study Evaluating Rocatinlimab in Moderate-to-severe Atopic Dermatitis (ROCKET-IGNITE) (NCT05398445) | Amgen | 2022-05-31 |
| Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy (NCT05326490) | PegBio Co., Ltd. | 2022-05-30 |
| Study of Mepolizumab-based Regimen Compared to Conventional Therapeutic Strategy in Patients With Eosinophilic Granulomatosis With Polyangiitis (E-merge) (NCT05030155) | Assistance Publique - Hôpitaux de Paris | 2022-05-30 |
| A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis (NCT05076175) | Bristol-Myers Squibb | 2022-05-30 |
| TACE/HAIC Combined With Lenvatinib and Sintilimab in Neoadjuvant Therapy for Intermediate-stage HCC (NCT05250843) | Third Affiliated Hospital, Sun Yat-Sen University | 2022-05-30 |
| Resolution of Sickle Cell Leg Ulcers With Voxelotor (NCT05561140) | Pfizer | 2022-05-30 |
| Efficacy and Safety of Sirolimus in Children and Adolescents With Juvenile Nasopharyngeal Angiofibroma (JNA) (NCT05549167) | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 2022-05-30 |
| A Study to Evaluate the Immunogenicity and Safety of Two Recombinant Protein COVID-19 Vaccines in Population Aged ≥18 Years as Booster Vaccines (NCT05323461) | Sinocelltech Ltd. | 2022-05-30 |
| Perioperative Iron for Colorectal Cancer (PICoC Study) (NCT05177484) | The Royal Wolverhampton Hospitals NHS Trust | 2022-05-30 |
| Gentuximab Combined With Paclitaxel Compared With Placebo Combined With Paclitaxel for Gastric Adenocarcinoma. (NCT05919381) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2022-05-30 |
| A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB (NCT05183646) | Dimerix Bioscience Pty Ltd | 2022-05-30 |
| Nifekalant Versus Amiodarone in New-Onset Atrial Fibrillation After Cardiac Surgery (NCT05169866) | Beijing Anzhen Hospital | 2022-05-29 |
| Lipiodol-TACE With Idarubicin for Hepatocellular Carcinoma (NCT05280444) | Zhongda Hospital | 2022-05-28 |
| Sequential Immunization of Two Doses of Inactivated COVID-19 Vaccine (Omicron) in Vaccinated Population Aged 18 Years and Above (NCT05382871) | China National Biotec Group Company Limited | 2022-05-27 |
| Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery? (NCT05021263) | Thomas Jefferson University | 2022-05-27 |
| Evaluation of Full Versus Fractional Dose of COVID-19 Vaccine Given as a Booster for the Prevention of COVID-19 in Adults in Mongolia. (NCT05265065) | Murdoch Childrens Research Institute | 2022-05-27 |
| Tenecteplase Compared to Alteplase for Patients With Large Vesel Oclusion Suspicion Before Thrombectomy (NCT05626972) | Hospital Universitari Vall d'Hebron Research Institute | 2022-05-27 |
| Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy (NCT04637594) | Alliance for Clinical Trials in Oncology | 2022-05-27 |
| Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial (NCT05341180) | All India Institute of Medical Sciences, Bhubaneswar | 2022-05-27 |
| Randomization to Endovascular Treatment Alone or Preceded by Systemic Thrombolysis With Tenecteplase in Ischemic Stroke (NCT05199194) | Hospital Moinhos de Vento | 2022-05-27 |
| Dapagliflozin and Renal Surrogate Outcomes in Advanced Chronic Kidney Disease (NCT05196347) | Kaohsiung Medical University | 2022-05-27 |
| To Evaluate SSD8432/Ritonavir in Adults With COVID-19 (NCT05373433) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2022-05-26 |
| A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer (NCT05433480) | Betta Pharmaceuticals Co., Ltd. | 2022-05-25 |
| Establishment of Precise Diagnosis and Treatment System for Refractory Chronic Rhinosinusitis (NCT05390255) | Beijing Tongren Hospital | 2022-05-25 |
| Phase 3 Boosting Study for the SARS-CoV-2 rS Variant Vaccines (NCT05372588) | Novavax | 2022-05-25 |
| A Phase 3 Study to Assess the Safety and Efficacy of Pitolisant in Adult Patients With Idiopathic Hypersomnia (NCT05156047) | Harmony Biosciences Management, Inc. | 2022-05-25 |
| Efficacy of Botulinum Toxin A in the Treatment of Bruxism-related Symptomatology (NCT04722809) | Centre Hospitalier Universitaire Dijon | 2022-05-25 |
| Targeting the Endothelial Glycocalyx to Enhance Vascular Function and Exercise-Induced Vascular Adaptations in Type 2 Diabetes (NCT05205005) | VA Office of Research and Development | 2022-05-25 |
| Study of Atropine Therapeutic Effect on Myopic Progression (NCT05529056) | LitePharmTech Co., Ltd. | 2022-05-25 |
| Comparison of Efficacy, Pharmacodynamics, Safety, and Immunogenicity Between Bmab 1000 and Prolia® in Postmenopausal Women With Osteoporosis (NCT05345691) | Biocon Biologics UK Ltd | 2022-05-24 |
| Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia (NCT05063994) | Neurocrine UK Limited | 2022-05-24 |
| Ensartinib as Adjuvant Treatment in Anaplastic Lymphoma Kinase (ALK) Positive Non-small Cell Lung Cancer (NCT05341583) | Betta Pharmaceuticals Co., Ltd. | 2022-05-24 |
| Using Doxepin for Urticaria (NCT05115136) | State University of New York - Upstate Medical University | 2022-05-23 |
| Efficacy and Safety of XC8, Film-coated Tablets, 40 mg in Patients With Dry Non-productive Cough Against Acute Respiratory Viral Infection (NCT05273619) | Valenta Pharm JSC | 2022-05-23 |
| A Long-term Trial of OPA-15406 in Infants With Atopic Dermatitis (NCT05372653) | Otsuka Pharmaceutical Co., Ltd. | 2022-05-23 |
| Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer (NCT02201381) | Health Clinics Limited | 2022-05-23 |
| A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) (NCT05269355) | PTC Therapeutics | 2022-05-23 |
| Innovating(IN) Shorter(S), All- Oral, Precised(P), Individualized(I) Treatment Regimen(RE) for Rifampicin Resistant Tuberculosis(INSPIRE-TB) (NCT05081401) | Huashan Hospital | 2022-05-23 |
| Platelet-Rich Plasma for Stress Urinary Incontinence (NCT05390970) | Annah J. Vollstedt | 2022-05-23 |
| Investigating the Efficacy, Safety and PK of Roxadustat (FG-4592) for Treatment of Anemia in Pediatric Patients With CKD (NCT04621331) | Kyntra Bio | 2022-05-23 |
| A Study of ARX788 Combined With Pyrotinib Maleate Versus TCBHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients (NCT05426486) | Caigang Liu | 2022-05-23 |
| Effect of Autogenous Demineralized Dentin as a Bone Graft Substitute in Management of Periodontal Intrabony Defects (NCT05445102) | Cairo University | 2022-05-22 |
| Study of Epetraborole in Patients With Treatment-refractory MAC Lung Disease (NCT05327803) | AN2 Therapeutics, Inc | 2022-05-20 |
| Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH) (NCT05416307) | Electra Therapeutics Inc. | 2022-05-19 |
| A Phase II/III Trial to Evaluate the Efficacy and Safety of QL1706 in Patients With Nasopharyngeal Carcinoma (NCT05576272) | Qilu Pharmaceutical Co., Ltd. | 2022-05-19 |
| A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS) (NCT05123703) | Hoffmann-La Roche | 2022-05-19 |
| Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid Leukemia (NCT05356169) | Institute of Hematology & Blood Diseases Hospital, China | 2022-05-19 |
| A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes (NCT05018585) | Diamyd Medical AB | 2022-05-19 |
| A Study to Learn About the Long-term Safety of Rimegepant for the Acute Treatment of Migraine in Chinese Participants (NCT05371652) | Pfizer | 2022-05-19 |