| Methadone as an Alternative Treatment for Children Underdoing HSCT (NCT06940570) | University of Texas Southwestern Medical Center | 2028-01-01 |
| National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem-Cell (MSC) Therapy in Non-viral Acute on Chronic Liver Failure (ACLF) Patients - Phase-III Trial (NCT07075315) | Institute of Liver and Biliary Sciences, India | 2028-01-01 |
| Study to Evaluate the effIcacy and Safety of Abelacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral Anticoagulation (NCT07739888) | Novartis Pharmaceuticals | 2027-12-30 |
| Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash (NCT04575948) | Misr International University | 2027-12-01 |
| Dantrolene in Statin-induced Myopathy (NCT06966843) | Tanta University | 2027-10-01 |
| Dose Response Study of Transdermal Human Insulin in Patients (NCT05159453) | Transdermal Delivery Solutions Corp | 2027-09-02 |
| Evaluation of Efficacy and Safety of a Single Dose of Exa-cel in Participants With Severe Sickle Cell Disease, βS/ βC Genotype (NCT05951205) | Vertex Pharmaceuticals Incorporated | 2027-07-31 |
| GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD) (NCT05303701) | Samsung Pharmaceutical Co., Ltd. | 2027-07-01 |
| Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease (NCT07620405) | Minghui Pharmaceutical (Hangzhou) Ltd | 2027-07-01 |
| Sildenafil to Prevent and Reduce Cancer Related Cognitive Impairment (NCT06800092) | The University of Texas Medical Branch, Galveston | 2027-06-15 |
| Clinical Trial of DN022150 Combined With AG Chemotherapy as First-line Treatment for Locally Advanced or Metastatic Pancreatic Cancer With KRAS G12D Mutation (NCT07656376) | Jiangxi Kvvit Pharmaceutical Co., Ltd. | 2027-06-06 |
| Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma (NCT02864888) | Burzynski Research Institute | 2027-06-01 |
| Study of Sugemalimab (or Placebo) Plus PGemOx Regimen in Participants With Extranodal NK/T-Cell Lymphoma (NCT05700448) | CStone Pharmaceuticals | 2027-06-01 |
| Evaluation of the Contraceptive Efficacy and Safety of a New Concentration of an Antiandrogenic Progestogen Combined With a Reduced-Dose Estrogen (LUNA) (NCT07714616) | Eurofarma Laboratorios S.A. | 2027-05-31 |
| Valproic AcId for Traumatic BRAin INjury Trial (NCT07166393) | Northwestern University | 2027-05-01 |
| Collaborative Risk-stratified Investigation in Thrombosis-prone Inpatients With Critical Illness: Anticoagulation With LMWH in Teens for ThromboProphylaxis (CRITICAL-Teens-TP). (NCT06628778) | Johns Hopkins All Children's Hospital | 2027-04-15 |
| Aspirin Versus Clopidogrel in Chronic Coronary Syndrome in Arabian Gulf Countries (NCT07572747) | Khalid F Alhabib | 2027-04-01 |
| A Study to Investigate the Efficacy and Safety of Roxadustat (FG-4592) for Treating Anemia in Participants With Myelodysplastic Syndromes (MDS) (NCT07722988) | Kyntra Bio | 2027-04-01 |
| Trial to Evaluate the Immunogenicity and Safety of the Co-administration of Live Attenuated Dengue and Chikungunya Vaccines Compared to Separate Administration in Adults Aged 18 to 59 Years. (NCT06973772) | Butantan Institute | 2027-03-31 |
| Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis (NCT07578116) | SWOG Cancer Research Network | 2027-03-09 |
| Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial (NCT07388524) | National Cancer Institute (NCI) | 2027-03-02 |
| Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old (NCT05249556) | Immedica Pharma AB | 2027-03-01 |
| Safety and Efficacy Study of Safusidenib in Participants With Grade 2 IDH1-Mutant Glioma (NCT07712757) | Nuvation Bio Inc. | 2027-03-01 |
| Rct Assessing Pregnancy - Piroxicam for Ec With Levonorgestrel (NCT07449299) | University of Utah | 2027-03-01 |
| Individualized Prolonged Luteal Support After Fresh Embryo Transfer in Women With Low Progesterone (NCT07613528) | University Hospital, Montpellier | 2027-03-01 |
| Testing the Investigational Medication Pembrolizumab After Kidney Removal for Patients With Non-Clear Cell Renal Cell Carcinoma (NCT07689240) | National Cancer Institute (NCI) | 2027-02-10 |
| Phase 3b Trial To Evaluate Safety And Immune Response (Superiority) of a Two-Dose Butantan-DV Regimen And The Standard Single Dose In Dengue-Naive Children/Adolescents and Immune Response (Non-inferiority) in a Manufacturing Facility Change (DEN-06-IB) (NCT07712926) | Butantan Institute | 2027-02-01 |
| Combined Nutrition and Parenting Study (NCT07490899) | University of South Carolina | 2027-02-01 |
| Phase 3 Long Term Safety Extension Study of LUM-201 in Children With Growth Hormone Deficiency (NCT07129759) | Lumos Pharma | 2027-02-01 |
| Phase 3 Study to Evaluate the Efficacy and Safety of Oral Minoxidil (N1087) in Men With Androgenetic Alopecia. (NCT07529977) | Eurofarma Laboratorios S.A. | 2027-01-31 |
| A Study Comparing a New Drug (Surovatamig) With Standard Radiotherapy With or Without Rituximab in Adults With Limited Stage Nodal Follicular Lymphoma (NCT07736950) | Australasian Leukaemia and Lymphoma Group | 2027-01-12 |
| Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer (NCT07765433) | ECOG-ACRIN Cancer Research Group | 2027-01-11 |
| AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight (NCT07668401) | Novo Nordisk A/S | 2027-01-07 |
| Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract Cancer (NCT07745296) | UNICANCER | 2027-01-02 |
| Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin (NCT07418554) | University Hospital, Strasbourg, France | 2027-01-01 |
| Accelerated vs Standard Approach to Continuous Veno-venous Hemodiafiltration Post-hemoperfusion (ASAP) in Severe Acute Diquat Poisoning (NCT06966765) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2027-01-01 |
| Efficacy and Safety of Tenecteplase Among acutE Ischemic Stroke Patients With Recent Ingestion of Direct Oral Anticoagulant (NCT07621796) | Hackensack Meridian Health | 2027-01-01 |
| Prediction and Prevention of Bloodstream Infections After Kidney Transplantation (NCT07407673) | Susanne Dam Nielsen, MD, DMSc | 2027-01-01 |
| RB-PDT for Fusarium Keratitis: The LUMIERE Study (NCT07743489) | Stanford University | 2027-01-01 |
| A Randomized Phase 3 Study to Evaluate the Efficacy and Safety of NXC-201 Compared With Daratumumab With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) in Newly Diagnosed Systemic AL Amyloidosis (NCT07709715) | Nexcella Inc. | 2027-01-01 |
| CBD Supplementation in Brazilian Jiu-Jitsu Athletes (NCT07552974) | Associação Pan-Americana Multidisciplinar de Endocanabinologia | 2027-01-01 |
| Primary Prophylaxis of Clostridioides Difficile Infection With Oral Vancomycin (NCT07221708) | University of Maryland, Baltimore | 2027-01-01 |
| Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Disease (NCT05698979) | University Hospital, Toulouse | 2027-01-01 |
| ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3 (NCT06716021) | Milestone Pharmaceuticals Inc. | 2027-01-01 |
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) (NCT07463040) | Institute of Tropical Medicine, Belgium | 2027-01-01 |
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia (NCT06488794) | University Hospital Fattouma Bourguiba | 2027-01-01 |
| Anti-PCSK9 Antibody Tafolecimab and Anti-PD-1 Antibody Sintilimab Combined With Neoadjuvant Chemoradiotherapy for pMMR/ MSS Locally Advanced Rectal Cancer : A Prospective, Multicenter, Randomized, Open-Label, Parallel-Controlled Trial (NCT07686796) | Guangdong Provincial People's Hospital | 2027-01-01 |
| Tarlatamab and Durvalumab vs. Durvalumab Alone for Limited-Stage-Small Cell Lung Cancer (NCT07637513) | PrECOG, LLC. | 2027-01-01 |
| A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With Schizophrenia (NCT07084831) | European Group for Research In Schizophrenia | 2027-01-01 |
| Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of N1087 in Participants With Female Pattern Hair Loss (MINORA-WOMEN) (NCT07303322) | Eurofarma Laboratorios S.A. | 2027-01-01 |
| A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PD (NCT07470164) | Jaeb Center for Health Research | 2027-01-01 |
| Safety of F14 Following Total Knee Replacement (NCT04860635) | Arthritis Innovation Corporation | 2027-01-01 |
| This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcting Early-onset Vitamin B12 Deficiency in Adult Patients Using Proton Pump Inhibitors (PPIs). The Primary Outcome is the Change in Serum Vitamin B12 Levels Over a 6-week (NCT06966856) | Tanta University | 2026-12-30 |
| Clinical Efficacy of Adebrelimab With or Without Apatinib Mesilate and SOX Neoadjuvant Therapy in Locally Advanced Gastric Cancer (NCT07314203) | Fujian Medical University | 2026-12-25 |
| Study of Efficacy and Safety of FRSW107 in Pediatric Patients With Severe Hemophilia A (NCT06136507) | Hangzhou Gensciences Biopharmaceutical Co., Ltd. | 2026-12-25 |
| Prospective Trial of the Efficacy and Safety of a Personalized Regimen of High-dose Aflibercept 8mg on Treatment-naive Polypoidal Choroidal Vasculopathy: the PALLAS Trial (NCT07389980) | Yeungnam University College of Medicine | 2026-12-24 |
| Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in Participants With Pulmonary Fibrosis (NCT07441408) | Bristol-Myers Squibb | 2026-12-16 |
| A Study of the Efficacy and Safety of FXS6837 Capsules Compared to Eculizumab for 24 Weeks in Patients With PNH. (NCT07747090) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2026-12-10 |
| Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin Lymphoma (NCT07572123) | National Cancer Institute (NCI) | 2026-12-04 |
| Testing Short-Course Radiation Versus Standard-Course Radiation for Soft Tissue Sarcomas That Need Surgery and Radiation (NCT07615049) | SWOG Cancer Research Network | 2026-12-02 |
| PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma (NCT06448286) | Jonsson Comprehensive Cancer Center | 2026-12-01 |
| Enhancing Amoxicillin Pharmacokinetics and Pharmacodynamics Parameters With Probenecid in Bone and Joint Infections (NCT07764302) | Assistance Publique - Hôpitaux de Paris | 2026-12-01 |
| Treatment of Chronic Thyroid Eye Disease With MHB018A (NCT07622121) | Minghui Pharmaceutical (Hangzhou) Ltd | 2026-12-01 |
| Tricaprilin Phase 3 ALTER-AD (Alternative-Alzheimer Disease) Study (NCT05809908) | Cerecin | 2026-12-01 |
| Efficacy and Safety of a Repurposed Drug Added to the Combination of Len Plus Pem in Advanced Endometrial Cancer (NCT05077215) | Evergreen Therapeutics, Inc. | 2026-12-01 |
| Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic Syndrome (NCT07770282) | All India Institute of Medical Sciences, Bhubaneswar | 2026-12-01 |
| Intracerebroventricular Tralesinidase Alfa in Participants With MPS IIIB (Sanfilippo Syndrome Type B) (NCT07579910) | Spruce Biosciences | 2026-12-01 |
| International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial (NCT06566183) | NYU Langone Health | 2026-12-01 |
| A Sequential Phase 2/3 Study of APL2 in Patients With Focal Segmental Glomerulosclerosis (NCT07213960) | Apellis Pharmaceuticals, Inc. | 2026-12-01 |
| Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone (NCT07225972) | New York Medical College | 2026-12-01 |
| 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome (NCT07290530) | Nacuity Pharmaceuticals, Inc. | 2026-12-01 |
| Dalbavancin Therapy for Infective Endocarditis (NCT07699211) | Stefan Hagel | 2026-12-01 |
| Treatment of Active Thyroid Eye Disease With MHB018A in a Randomized, Placebo-Controlled Study (NCT07622108) | Minghui Pharmaceutical (Hangzhou) Ltd | 2026-12-01 |
| Efficacy, Safety, and Tolerability of Levonorgestrel Vaginal System (NCT07734155) | Chemo Research | 2026-12-01 |
| IGNITE-TX Phase III: (Identifying Individuals for Genetic Testing & Treatment) Intervention (NCT07318363) | M.D. Anderson Cancer Center | 2026-12-01 |
| Evaluation of Iopofosine I 131 vs. R-CD in WM Patients (NCT07766421) | Cellectar Biosciences, Inc. | 2026-12-01 |
| Oxfendazole in Mild Parenchymal Brain Cysticercosis (NCT06565507) | Universidad Peruana Cayetano Heredia | 2026-12-01 |
| A Study to Evaluate the Maintenance of Efficacy and Long-term Safety of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 1) (NCT07733947) | Caliway Biopharmaceuticals Co., Ltd. | 2026-12-01 |
| A Study to Test the Non-Inferiority of Ferric Bepectate IV Against Ferric Carboxymaltose in Patients With Iron Deficiency Anemia (NCT07687784) | AFT Pharmaceuticals, Ltd. | 2026-12-01 |
| HEME-25: Open-Label Feasibility Study of Elranatamab Utilized in Newly Diagnosed Plasmablastic Lymphoma With or Without HIV (NCT07647432) | University of Illinois at Chicago | 2026-12-01 |
| Pericardial Imaging Study (NCT07245849) | Ottawa Heart Institute Research Corporation | 2026-12-01 |
| Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences (NCT07124533) | Loma Linda University | 2026-12-01 |
| A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease (NCT07717411) | Hoffmann-La Roche | 2026-11-30 |
| A Clinical Study Comparing Ankle Swelling Caused by Two Different Blood Pressure Medications, Levamlodipine and Amlodipine, in Post-menopausal Women With Mild High Blood Pressure. (NCT07618806) | Zentiva, k.s. | 2026-11-30 |
| iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TRIAD) (NCT06560333) | Eurofarma Laboratorios S.A. | 2026-11-30 |
| Efficacy and Safety of Two Fixed-dose Combinations in Men with Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia. (BENIPRO) (NCT06546735) | Eurofarma Laboratorios S.A. | 2026-11-30 |
| Fixed-dose Combination of an Angiotensin Receptor Blocker and Thiazide Diuretic for Essential Hypertension (NCT06608472) | Eurofarma Laboratorios S.A. | 2026-11-30 |
| Efficacy and Safety of Cryotherapy Followed by Tirbanibulin Ointment for Actinic Keratosis on the Scalp and Forehead (NCT07273656) | University Hospital, Lille | 2026-11-30 |
| A Study to Learn About the Safety of Diroximel Fumarate (DRF) and Dimethyl Fumarate (DMF) and Their Effects on Relapses in Pediatric Participants With Relapsing Forms of Multiple Sclerosis (RMS) (NCT07483632) | Biogen | 2026-11-16 |
| Study to Assess the Prophylactic Efficacy and Safety of Sebaloxavir Marboxil Tablets/Oral Suspension for Influenza Prevention in Household Contacts Aged ≥2 Years. (NCT07730346) | Nanjing Zenshine Pharmaceuticals | 2026-11-07 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections (NCT06800248) | Swiss Tropical & Public Health Institute | 2026-11-06 |
| Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine (NCT07361432) | VA Office of Research and Development | 2026-11-02 |
| Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma (NCT07349693) | Everfront Biotech Co., Ltd. | 2026-11-01 |
| Efficacy of Lipoic Acid on Chronic Ischemic Heart Failure Patients (NCT07725484) | Shanghai Zhongshan Hospital | 2026-11-01 |
| Safety, Tolerability, and Efficacy of PLX-200 in Patients With CLN3 (NCT04637282) | Polaryx Therapeutics, Inc. | 2026-11-01 |
| Combination Therapies for Trichuris Trichiura Infection in Schoolchildren in Honduras (NCT07661316) | Mundo Sano Foundation | 2026-11-01 |
| A Study to Assess How Well the Study Medicine IPN60340 Works in Combination With Azacitidine and Venetoclax, Compared to Placebo in Combination With Azacitidine and Venetoclax, in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Cannot Receive Intensive Chemotherapy (NCT07623187) | Ipsen | 2026-11-01 |
| Randomized, Placebo-crontrolled Clinical Trial Evaluating the Efficacy and Safety of Heparan Sulfate 120 mg Prolonged-Release Tablets Compared With Placebo in Patients With Chronic Venous Disease (NCT07684833) | Barbara Maglione | 2026-11-01 |
| Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis (NCT07754617) | Rhode Island Hospital | 2026-11-01 |
| A Study to Evaluate the Efficacy and Safety of CHF10196 Tablets (Florensocatib) Compared With Placebo in Male and Female Participants 12 to 85 Years of Age With Bronchiectasis (NCT07577804) | Chiesi Farmaceutici S.p.A. | 2026-11-01 |