| Characterization of Bronchodilator Response in Children With Bronchiolitis Using Phenotypic and Genotypic Features (NCT06946264) | Nemours Children's Clinic | 2022-07-08 |
| Study to Evaluate and Compare the Efficacy and Safety of AZM and AML Combined and Alone in Mild-to-moderate Essential Hypertensive Subjects (NCT05385770) | Celltrion | 2022-07-08 |
| Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (NCT05174169) | NRG Oncology | 2022-07-08 |
| Clinical Study to Evaluate the Possible Efficacy and Safety of L- Carnitine and Sildenafil in Children Having Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity (NCT05584956) | Tanta University | 2022-07-08 |
| Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Macular Degeneration (NCT05439629) | Bio-Thera Solutions | 2022-07-07 |
| iGlarLixi vs IDegAsp in Chinese Participants After OAD(s) (NCT05413369) | Sanofi | 2022-07-07 |
| Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia (NCT05079230) | Gilead Sciences | 2022-07-07 |
| Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD (NCT05439616) | AbbVie | 2022-07-07 |
| A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy (NCT05337553) | Biohaven Pharmaceuticals, Inc. | 2022-07-06 |
| Early Stage Follicular LymphOma and RadioTherapy PLUS Anti-CD20 Antibody (NCT05045664) | Heidelberg University | 2022-07-06 |
| A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer (NCT05415215) | Hoffmann-La Roche | 2022-07-05 |
| An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia (NCT05426733) | Albireo, an Ipsen Company | 2022-07-05 |
| The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer (NCT05984485) | Sun Yat-sen University | 2022-07-05 |
| Clinical Efficacy and Safety Evaluation of Irbesartan and Amlodipine Combined Therapy in Essential Hypertension Patients (NCT05476354) | Handok Inc. | 2022-07-05 |
| A Phase 3 Study to Compare Biosimilar Denosumab With Prolia® (NCT05405725) | Enzene Biosciences Ltd. | 2022-07-04 |
| A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease (NCT05403827) | Kowa Research Institute, Inc. | 2022-07-03 |
| Abatacept in Immune Checkpoint Inhibitor Myocarditis (NCT05335928) | Massachusetts General Hospital | 2022-07-02 |
| Toripalimab Plus Radiotherapy for Elderly Esophageal Cancer Patients Treated With Non-chemotherapy Strategy (NCT05817201) | Taizhou Hospital | 2022-07-01 |
| ChiCGB vs BEAM in High-risk or R/R Lymphomas (NCT05466318) | Sichuan University | 2022-07-01 |
| Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis. (NCT05267613) | AstraZeneca | 2022-07-01 |
| Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia (NCT04001010) | Tetra Bio-Pharma | 2022-07-01 |
| Clomiphene Citrate in Infertile Men With Idiopathic Oligoasthenozoospermia (NCT06564961) | Shakeela Ishrat | 2022-07-01 |
| Efficacy of Pilocarpine 1% in Presbyopia (NCT05578001) | Isfahan University of Medical Sciences | 2022-07-01 |
| Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) (NCT05354141) | Direct Biologics, LLC | 2022-07-01 |
| Role of Oral Lactoferrin in Prevention of Recurnt Bacterial Vaginosis in Pregnancy (NCT05669963) | Zagazig University | 2022-07-01 |
| Buprenorphine for Probationers and Parolees: Bridging the Gap Into Treatment (NCT03616236) | Friends Research Institute, Inc. | 2022-07-01 |
| The Influence of 3D Surgical Template on the Contour of Bone Augmentation, in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation (NCT06312384) | Mansoura University | 2022-07-01 |
| Ivabradine Effects in Cardiogenic Shock Requiring Inotropic Support (NCT05594342) | The Young Investigator Group of Cardiovascular Research | 2022-07-01 |
| Effect of Liraglutide on Subclinical Atherosclerosis in Patients With Type 1 Diabetes Mellitus (NCT05467514) | David Sanchez Garcia | 2022-07-01 |
| Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome (NCT05391789) | Huashan Hospital | 2022-07-01 |
| Concurrent Chemoradiotherapy Combined With Adjuvant Chemotherapy Treated Advanced Cervical Cancer (NCT05735145) | Fourth Affiliated Hospital of Guangxi Medical University | 2022-07-01 |
| Investigation of Eluxadoline for Diabetic Diarrhea (NCT04313088) | Temple University | 2022-07-01 |
| G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for High-risk MDS Undergoing Allo-HSCT (NCT05453552) | Nanfang Hospital, Southern Medical University | 2022-07-01 |
| Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour (NCT05230758) | Donald Mabbott | 2022-07-01 |
| Treatment With Olverembatinib in CML-CP Patients Who Failed to at Least Two Previously Administered Second-generation TKIs. (NCT05311943) | Shenzhen Second People's Hospital | 2022-07-01 |
| Oral Vitamin D and Toll Like Receptor in Spondylitis Tuberculosis (NCT05376189) | Hasanuddin University | 2022-07-01 |
| A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) (NCT05276063) | Sling Therapeutics, Inc. | 2022-07-01 |
| Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery (NCT04918173) | Octapharma | 2022-07-01 |
| A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC (NCT05433597) | Sun Yat-sen University | 2022-07-01 |
| Topical CBD for Musculoskeletal Pain (NCT05411913) | Apothyx, Co. | 2022-07-01 |
| Effect of Colchicine on the Progression of Aortic Valve Stenosis - A Pilot Study (NCT05253794) | Ottawa Heart Institute Research Corporation | 2022-07-01 |
| To Evaluate the Efficacy and Safety of TQB3616 in Combination With Fulvestrant Versus Placebo in Combination With Fulvestrant in Previously Untreated Hormone-receptor (HR)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Advanced Breast Cancer (NCT05365178) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2022-07-01 |
| Targeting Leukotrienes in Kidney Disease (NCT05362474) | University of Colorado, Denver | 2022-07-01 |
| A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer (NCT06082180) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2022-07-01 |
| A Trial of SHR0410 Injection for the Treatment of Pain After Laparoscopic Surgery (NCT05459220) | Jiangsu HengRui Medicine Co., Ltd. | 2022-07-01 |
| Phase III Trial of Sirolimus in IBM (NCT04789070) | University of Kansas Medical Center | 2022-07-01 |
| G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT (NCT05449899) | Nanfang Hospital, Southern Medical University | 2022-07-01 |
| A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD) (NCT04786574) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2022-07-01 |
| Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection (NCT05447078) | University of Mississippi Medical Center | 2022-07-01 |
| Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia (NCT05682807) | Tanta University | 2022-06-30 |
| Study Comparing Dural Puncture Epidural With Epidural and Combined Spinal Epidural Anesthesia for Obstetric Analgesia. (NCT05196256) | Brugmann University Hospital | 2022-06-30 |
| Diosmin as Adjuvant Therapy in Treatment of Non-bleeding Peptic Ulcer (NCT05670457) | Tanta University | 2022-06-30 |
| Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension (NCT04927299) | Laboratorios Silanes S.A. de C.V. | 2022-06-30 |
| Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder (NCT05303064) | Alkermes, Inc. | 2022-06-30 |
| Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis (NCT04991116) | Sun Pharmaceutical Industries Limited | 2022-06-30 |
| Evaluate the Safety of HBM9161 (HL161) Subcutaneous Injection in Patients With Generalized Myasthenia Gravis (NCT05332210) | Harbour BioMed (Guangzhou) Co. Ltd. | 2022-06-30 |
| Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2) (NCT05327296) | Sedana Medical | 2022-06-30 |
| Efficacy and Safety Study of Etripamil Nasal Spray Self-Administration for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia (NCT05410860) | Corxel Pharmaceuticals | 2022-06-30 |
| A Phase III Multi Regional Clinical Trial (MRCT) of Tricaprilin in Mild to Moderately Severe Probable Alzheimer's Disease With Optional Open Label Extension (NCT04187547) | Cerecin | 2022-06-30 |
| A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C (NCT05163288) | IntraBio Inc | 2022-06-30 |
| A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium (NCT05456425) | Cloudbreak Therapeutics, LLC | 2022-06-30 |
| Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease (NCT05576818) | Tanta University | 2022-06-30 |
| Effect of Pentoxifylline Versus Probiotic on Preterm Neonates With Necrotizing Enterocolitis (NCT06422000) | Tanta University | 2022-06-30 |
| Nonavalent HPV Vaccine in the Treatment of Difficult-to-treat Palmo-plantar Warts (NCT04814446) | Assistance Publique - Hôpitaux de Paris | 2022-06-29 |
| Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer (NCT05257408) | Corcept Therapeutics | 2022-06-29 |
| Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes. (NCT05401357) | Amneal Pharmaceuticals, LLC | 2022-06-29 |
| Comparison of Prophylactic Use of Tramadol Versus Ketamine for Prevention of Post Spinal Anesthesia Shivering (NCT07043049) | Syed Muhammad Abbas | 2022-06-29 |
| A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects (NCT05253209) | Asklepion Pharmaceuticals, LLC | 2022-06-29 |
| Caffeine Kinetics and CrossFit®-Specific Performance (NCT05516212) | Poznan University of Physical Education | 2022-06-29 |
| Comparing Tissue Adhesives in Port Site Closure (NCT05492721) | The University of Texas Health Science Center, Houston | 2022-06-29 |
| TAB014 Compared to Lucentis® in Patients with Neovascular Age-related Macular Degeneration (NCT05461339) | BioDlink Biopharm Co., Ltd. | 2022-06-28 |
| A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection (NCT05470387) | Palisade Bio | 2022-06-28 |
| Clinical Study to Compare Efficacy and Safety of AVT06 and EU-Eylea (ALVOEYE) (NCT05155293) | Alvotech Swiss AG | 2022-06-28 |
| Angiotensin II in Liver Transplantation (NCT04901169) | University of California, San Francisco | 2022-06-28 |
| Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung (NCT05058651) | National Cancer Institute (NCI) | 2022-06-28 |
| A Study to Evaluate the Safety and Tolerability of Tirbanibulin Ointment 1% in Adult Participants With Actinic Keratosis (NCT05279131) | Almirall, S.A. | 2022-06-28 |
| Dronabinol After Arthroscopic Surgery (NCT05335252) | Northwestern University | 2022-06-28 |
| Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis (NCT05441488) | AB Science | 2022-06-28 |
| A Trial to Assess the Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With PLD (NCT05281328) | Camurus AB | 2022-06-28 |
| Comparing Efficacy and Safety of Bmab 1200 and Stelara in Patients With Moderate to Severe Chronic Plaque Psoriasis (NCT05335356) | Biocon Biologics UK Ltd | 2022-06-28 |
| UNAIR Inactivated COVID-19 Vaccine Phase III (Immunobridging Study) (NCT05508477) | Dr. Soetomo General Hospital | 2022-06-28 |
| A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS) (NCT05143177) | REDNVIA Co., Ltd. | 2022-06-27 |
| Mifepristone for Labor Induction (NCT05097326) | Stanford University | 2022-06-27 |
| Ketamine Treatment of Youth Suicide Attempters (NCT04763343) | Tatiana Falcone, MD | 2022-06-27 |
| PRP in ACLR to Prevent PTOA (NCT05412381) | Hospital for Special Surgery, New York | 2022-06-27 |
| Phase 3 Study to Assess the Efficacy and Safety of Batoclimab as Induction and Maintenance Therapy in Adult Participants With Generalized Myasthenia Gravis (NCT05403541) | Immunovant Sciences GmbH | 2022-06-27 |
| Efficacy and Safety of AJU-C52 in Essential Hypertension Patients (NCT06416865) | AJU Pharm Co., Ltd. | 2022-06-27 |
| Possible Immuno-Modulatory Effect of Tocilizumab in Patients With Refractory Status Epilepticus. (NCT05346666) | Damanhour University | 2022-06-25 |
| AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission (NCT05404906) | The First Affiliated Hospital of Soochow University | 2022-06-25 |
| A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery (NCT05147233) | Oculis | 2022-06-24 |
| Voxelotor Neurocognitive Function Study (NCT05228834) | Pfizer | 2022-06-24 |
| Safety and Immunogenicity of 20vPnC in Toddlers With 2 Prior Doses of Prevenar 13 (NCT05408429) | Pfizer | 2022-06-24 |
| Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (NCT04975997) | Celgene | 2022-06-23 |
| A Randomised Open-label Phase III Trial of REduced Frequency Pembrolizumab immuNothErapy for First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC) (NCT05085028) | Imperial College London | 2022-06-23 |
| SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM (NCT05405166) | Sanofi | 2022-06-23 |
| Upifitamab Rilsodotin Maintenance in Platinum-Sensitive Recurrent Ovarian Cancer (UP-NEXT) (NCT05329545) | Mersana Therapeutics | 2022-06-23 |
| Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome (NCT05521438) | Quoin Pharmaceuticals | 2022-06-23 |
| Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD (NCT05346354) | Alexion Pharmaceuticals, Inc. | 2022-06-23 |
| The Prospective Evaluation of Peri-Operative Glucocorticoid Use in the Management of Cervicofacial Infections of Odontogenic Origin (NCT05951504) | University of Manitoba | 2022-06-22 |
| A Study of Lanadelumab (SHP643) in Chinese Participants With Hereditary Angioedema (HAE) (NCT05460325) | Takeda | 2022-06-22 |