| Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD (NCT05407636) | AbbVie | 2022-01-13 |
| The Study for Evaluating the Clinical Effectiveness and Safety of Respiratory Rehabilitation Software 'Redpill Breath'(COPD, Asthma, Lung Cancer, Etc.) (NCT05299385) | Lifesemantics Corp. | 2022-01-13 |
| Safety, Tolerability, and Immunogenicity of V110 or V114 Co-administered With a Booster Dose of mRNA-1273 in Healthy Adults (V110-911) (NCT05158140) | Merck Sharp & Dohme LLC | 2022-01-12 |
| Effects of a Peripherally Acting µ-opioid Receptor Antagonist on Recurrent Acute Pancreatitis (NCT04966559) | Asbjørn Mohr Drewes | 2022-01-12 |
| Efficacy, Safety and Costs of Methotrexate, Adalimumab, or Their Combination in Non-infectious Non-anterior Uveitis (NCT04798755) | Hospital San Carlos, Madrid | 2022-01-12 |
| Local Ablative Stereotactic Radiotherapy for Residual Hypermetabolic Lesion in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Long-term Responders to Immunotherapy (NCT05111197) | Institut Cancerologie de l'Ouest | 2022-01-12 |
| A 24-Week Efficacy and Safety Study to Assess Budesonide and Formoterol Fumarate Metered Dose Inhaler in Adult and Adolescent Participants With Inadequately Controlled Asthma (VATHOS) (NCT05202262) | AstraZeneca | 2022-01-12 |
| Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis (NCT05201638) | Immunic AG | 2022-01-12 |
| Interest of Famotidine in Children With Sickle Cell Disease (NCT05084521) | Assistance Publique - Hôpitaux de Paris | 2022-01-12 |
| An Efficacy and Safety Study of Basimglurant (NOE-101) in Patients With Trigeminal Neuralgia. (NCT05217628) | Noema Pharma AG | 2022-01-11 |
| Chemo-immunotherapy Plus Thoracic Radiotherapy in Extensive Stage Small-cell Lung Cancer (NCT05223647) | Norwegian University of Science and Technology | 2022-01-11 |
| Health Information Technology for COVID-19 Testing in Schools (SCALE-UP Counts) (NCT05112900) | University of Utah | 2022-01-11 |
| Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS (NCT05151471) | Shionogi | 2022-01-11 |
| Supplemental Perioperative Intravenous Crystalloids for Postoperative Nausea and Vomiting in Children Undergoing Oncological Surgery (NCT05658406) | Alexandria University | 2022-01-10 |
| Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7) (NCT05092360) | Mural Oncology, Inc | 2022-01-10 |
| Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors (NCT05057130) | Blokhin's Russian Cancer Research Center | 2022-01-10 |
| Radiofrequency Ablation Plus Radiotherapy for Small Hepatocellular Carcinoma (NCT03988998) | Guangxi Medical University | 2022-01-10 |
| Pharmacological and Behavioral Treatments After Bariatric Surgery: Maintenance Treatment (Stage 2a) (NCT04605081) | Yale University | 2022-01-10 |
| Evaluating the Efficacy and Tolerability of Ceradan Advanced Cream in the Treatment of Children With Atopic Dermatitis (NCT05136261) | KK Women's and Children's Hospital | 2022-01-10 |
| Effect of Soft Tissue Augmentation With an Acellular Dermal Matrix in Marginal Bone Levels Around Implants (NCT05156294) | Universidad Complutense de Madrid | 2022-01-10 |
| The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation (NCT05170464) | Western University, Canada | 2022-01-10 |
| Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT (NCT05011149) | IWK Health Centre | 2022-01-10 |
| Tobramycin Injection to Prevent Infection in Open Fractures (NCT04964947) | Massachusetts General Hospital | 2022-01-10 |
| Normoxemic Versus Hyperoxemic Extracorporeal Oxygenation in Patients Supported by Veino-arterial ECMO for Cardiogenic Shock (NCT04990349) | Centre Hospitalier Universitaire de Besancon | 2022-01-09 |
| Tamsulosin Assisted Ureteral Access Sheath Insertion (NCT05197088) | Sengkang General Hospital | 2022-01-09 |
| Evaluation of Safety and Immunogenicity of Inactivated Adjuvanted Polio Vaccine in Comparison With Licensed Inactivated Poliovirus Vaccine (NCT05163561) | Serum Institute of India Pvt. Ltd. | 2022-01-09 |
| Loxenatide Plus LNG-IUS in Endometrial Atypical Hyperplasia (NCT05172999) | Fudan University | 2022-01-08 |
| Caudal Block for Inguinal Hernioplasty in Children (NCT05958589) | University of Novi Sad | 2022-01-08 |
| Effect of Folic Acid and/or Pentoxifylline on Patients With Chronic Kidney Disease (NCT05284656) | Al-Azhar University | 2022-01-08 |
| A Phase Ⅲ Study of Hemay022 in Combination With AI In Advanced Breast Cancer (NCT06313983) | Tianjin Hemay Pharmaceutical Co., Ltd | 2022-01-08 |
| SI-B001 Combined With Osimertinib Mesylate Tablets in the Treatment of Recurrent Metastatic Non-small Cell Lung Cancer. (NCT05020769) | Sichuan Baili Pharmaceutical Co., Ltd. | 2022-01-06 |
| A Study to Evaluate Camrelizumab Combined With Famitinib as Subsequent Therapy in Patients With Advanced NSCLC (NCT05106335) | Jiangsu HengRui Medicine Co., Ltd. | 2022-01-06 |
| A Phase III, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of TD0069 Capsule for Patients With Mild to Moderate COVID-19 (NCT05249777) | Sao Thai Duong Joint Stock Company | 2022-01-06 |
| MAGNAM Trial, Magnesium Versus Amiodarone in Atrial Fibrillation in Critical Care (NCT05287191) | Sunnybrook Health Sciences Centre | 2022-01-05 |
| Fourth COVID-19 Vaccine Dose- mRNA1273 (NCT05230953) | Sheba Medical Center | 2022-01-05 |
| Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease (NCT05099770) | Prokidney | 2022-01-05 |
| A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older (NCT05027308) | Takeda | 2022-01-04 |
| Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain (NCT05037123) | NYU Langone Health | 2022-01-04 |
| A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy (NCT05071300) | Ionis Pharmaceuticals, Inc. | 2022-01-04 |
| A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM (NCT05174416) | LianBio LLC | 2022-01-04 |
| Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations (NCT05166889) | AstraZeneca | 2022-01-03 |
| Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients (NCT04939090) | Alliance for Clinical Trials in Oncology | 2022-01-03 |
| Betamethasone and Complications of Lower Third Molar Surgery (NCT07297264) | Shehab Ahmed Hamad | 2022-01-03 |
| Comparisons of Metabolic Effect of Sleeve Gastrectomy With Duodenojejunal Bypass and Sleeve Gastrectomy (MEDUSA): A Multicenter Randomized Controlled Trial (NCT05211375) | Seoul National University Bundang Hospital | 2022-01-03 |
| Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital (NCT04979884) | Alexandria University | 2022-01-03 |
| Preoperative Nutritional Optimization and Physical Exercise for Patients Scheduled for Elective Implantation for a Left-Ventricular Assist Device (NCT04205760) | RWTH Aachen University | 2022-01-02 |
| Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b) (NCT04599504) | Yale University | 2022-01-02 |
| Effect of Intravenous or Intrathecal Dexmedetomidine on Bupivacaine Spinal Block in Lower Abdominal Surgery (NCT06654531) | Al-Azhar University | 2022-01-02 |
| Direct Pulp Capping in Primary Molars (NCT05530954) | Mansoura University | 2022-01-01 |
| Radiotherapy Alone Versus Concurrent Chemo-radiotherapy for Nasopharyngeal Carcincoma Patients With Undectable EBV DNA After One Cylce Neoadjuvant Chemotherpy (NCT05674305) | Fudan University | 2022-01-01 |
| A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Clinical Efficacy and Safety of Yogliptin Tablets (NCT05318326) | Chengdu Easton Biopharmaceuticals Co,Ltd | 2022-01-01 |
| Phase Ⅱ and Ⅲ Trial of a SARS-CoV-2 Vaccine LYB001 (NCT05137444) | Yantai Patronus Biotech Co., Ltd. | 2022-01-01 |
| Intravenous Dexmedetomidin on Postoperative Pain After Hypospadias Repair in Children (NCT05194904) | Assiut University | 2022-01-01 |
| Neuroprotective Effects of Xenon Treatment in Patients with Cerebral Infarction (NCT05335109) | Negovsky Reanimatology Research Institute | 2022-01-01 |
| Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral Stricture (NCT06232005) | Ain Shams University | 2022-01-01 |
| Cladribine Combined With G-CSF and Cytarabine as a Salvage Treatment in R/R ALL (NCT05578378) | The First Affiliated Hospital of Soochow University | 2022-01-01 |
| Pharmacotherapy for Pediatric Obesity: A Phentermine Clinical Trial (NCT04678323) | University of Minnesota | 2022-01-01 |
| Topical Morphine for Analgesia in Patients With Skin Grafts (NCT00362219) | Rambam Health Care Campus | 2022-01-01 |
| Regional Anesthesia for Modified Radical Mastectomy With Axillary Lymph Node Dissection (NCT04239716) | Tanta University | 2022-01-01 |
| Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (NCT04238390) | The University of Queensland | 2022-01-01 |
| Intensified Treatments for Patients With Locally Advanced Nasopharyngeal Carcinoma With Detectable EBV DNA After One Cycle GP Regime Neoadjuvant Chemotherapy (NCT05772208) | Fudan University | 2022-01-01 |
| Paraesternal Blockade and Lactate Serum Levels in Patients With Cardiac Surgery. (NCT06608290) | Instituto Mexicano del Seguro Social | 2022-01-01 |
| Comparison of Fluid Resuscitation in Pediatric Burn Patients Using Crystalloids and With Albumin on Day Two. (NCT06224777) | King Edward Medical University | 2022-01-01 |
| Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars (NCT05146713) | Cairo University | 2022-01-01 |
| Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture (NCT05164081) | Umeå University | 2022-01-01 |
| Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients (NCT05443737) | University of California, San Diego | 2022-01-01 |
| Targeted Dose Study of ATG in Haploidentical Hematopoietic Stem Cell Transplantation (NCT05166967) | Chinese PLA General Hospital | 2022-01-01 |
| INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Superiority (NCT02832531) | Population Health Research Institute | 2022-01-01 |
| Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression (NCT05373680) | Tanta University | 2022-01-01 |
| Innate Donor Effector Allogeneic Lymphocyte Infusion After Stem Cell Transplantation: the IDEAL Trial (NCT05686538) | Rigshospitalet, Denmark | 2022-01-01 |
| Tranexamic Acid in Debridement Surgery of Burns on the Volume of Bleeding in Transfusion Requirements (NCT05855590) | Instituto Mexicano del Seguro Social | 2022-01-01 |
| Intraorbital Injection Versus Oral Steroid in Anterior Idiopathic Orbital Inflammation (NCT03958344) | Iran University of Medical Sciences | 2022-01-01 |
| The Efficacy and Safety of Mecobalamin in the Prevention of Capecitabine Induced Hand Foot Syndrome (NCT05165069) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2022-01-01 |
| Magnesium Sulphate to Bupivicaine in Serratus Anterior Plane Block in Modified Radical Mastectomy (NCT04429893) | Alexandria University | 2022-01-01 |
| Lubiprostone for Functional Constipation in the Under 18 Years Patients (NCT05144295) | Alexandria University | 2022-01-01 |
| #StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalisation and Household Transmission in COVID-19 (NCT04385264) | Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland | 2022-01-01 |
| A Study to Systematically Assess the Efficacy and Safety of Intravenous Albumin Infusions in Severe POTS (NCT03365414) | University of Alberta | 2022-01-01 |
| Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis (NCT05708625) | Zagazig University | 2022-01-01 |
| Chinese Herbal Medicine Treatment as Adjunct Therapy for Parkinson's Disease (NCT05001217) | Hong Kong Baptist University | 2022-01-01 |
| Herombopag + rhTPO in Severe Immune Thrombocytopenia (NCT05328804) | Yin Jie | 2022-01-01 |
| Effect of Tranexamic Acid and Calcium Dobesilate for Bleeding of Endometrial Origin (NCT06707051) | District Headquarters Teaching Hospital Sahiwal | 2022-01-01 |
| Comparison of PT-Cy at a Dose of 25 mg/kg/Day and PT-Cy at a Dose of 50 mg/kg/Day in GVHD Prophylaxis (NCT05158608) | National Research Center for Hematology, Russia | 2022-01-01 |
| PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer (NCT05236972) | Sun Yat-sen University | 2022-01-01 |
| Prophylactic LYMphatic Reconstruction (LYMbR) to Prevent Lymphedema After Node Dissection for Cutaneous Malignancies (NCT05136079) | Alberta Health Services, Calgary | 2022-01-01 |
| Effect of Topically-applied Milrinone or Nitroglycerin on Internal Mammary Artery Free Flow (NCT06301880) | Damascus University | 2022-01-01 |
| Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency (NCT05397665) | Applied Therapeutics, Inc. | 2022-01-01 |
| Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication (NCT06101420) | Ain Shams University | 2022-01-01 |
| Topical CBD for Musculoskeletal Pain (NCT05170451) | University of Virginia | 2022-01-01 |
| Study Of Comparing SAF-189s With Crizotinib In First Line ALK-Positive Advanced and Metastatic NSCLC (NCT06569420) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2021-12-31 |
| the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial) (NCT05527704) | Medical University of Warsaw | 2021-12-31 |
| A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH). (NCT05325203) | Shanghai Junshi Bioscience Co., Ltd. | 2021-12-31 |
| FUDR/Oxaliplatin HAI Plus Irinotecan vs. FOLFOXIRI Chemotherapy in Treating Initially Unresectable CRCLM (NCT03678428) | Sun Yat-sen University | 2021-12-31 |
| Efficacy and Safety Study of TPN171H Tablets in Erectile Dysfunction. (NCT05188989) | Vigonvita Life Sciences | 2021-12-31 |
| Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Viral Hepatitis B Phase 3 Trial. (NCT05115942) | Beijing Continent Pharmaceutical Co, Ltd. | 2021-12-30 |
| To Assess Allisartan Isoproxil/Sustained-Release Indapamide in Patients With Essential Hypertension Uncontrolled With Allisartan Isoproxil (NCT06500689) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2021-12-30 |
| Angiotensin-(1,7) Treatment in COVID-19: the ATCO Trial (NCT04332666) | Erasme University Hospital | 2021-12-30 |
| Evaluation of the Safety and Efficacy of Hemophilia B Gene Therapy Drug (NCT05203679) | Shanghai Xinzhi BioMed Co., Ltd. | 2021-12-30 |
| Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects (NCT05256017) | Drugs for Neglected Diseases | 2021-12-30 |
| The Efficacy and Safety of DWP14012 in Chinese Patients With Reflux Esophagitis (NCT05813561) | Daewoong Pharmaceutical Co. LTD. | 2021-12-30 |
| A Study of SHR-1701 Plus Bevacizumab and Chemotherapy in Non-Small-Cell-Lung-Cancer (NCT05132413) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2021-12-30 |