| Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities (NCT05104918) | Scotmann Pharmaceuticals | 2022-02-01 |
| Growth Hormone For Poor Ovarian Reserve Patients in ICSI Trials (NCT05602090) | Beni-Suef University | 2022-02-01 |
| Prolgolimab 250 mg Q3W in Patients With Unresectable or Metastatic Melanoma (NCT05783882) | Biocad | 2022-02-01 |
| Growth Hormone in Decompensated Liver Cirrhosis (NCT05253287) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2022-02-01 |
| Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (NCT05186818) | Cytokinetics | 2022-02-01 |
| An Open Label, Long Term Safety Study of REN001 in Primary Mitochondrial Myopathy Patients (Stride Ahead) (NCT05267574) | Reneo Pharma Ltd | 2022-02-01 |
| Efficacy and Safety of Intrathecal OAV101 (AVXS-101) in Pediatric Patients With Type 2 Spinal Muscular Atrophy (SMA) (NCT05089656) | Novartis Pharmaceuticals | 2022-02-01 |
| Evaluating the Efficacy and Safety of Nilotinib BE in Subjects With Early Alzheimer's Disease (NCT05143528) | KeifeRx, LLC | 2022-02-01 |
| Investigational and Comparative Study in the Management of Diabetic Nephropathy (NCT05487755) | Tanta University | 2022-02-01 |
| Rituximab Monotherapy for EBV-HLH and CAEBV (NCT05384743) | Beijing Friendship Hospital | 2022-02-01 |
| Nebulized Fentanyl for Respiratory Symptoms in Patients With COVID-19 (NCT05165992) | Hamad Medical Corporation | 2022-02-01 |
| Effect of Montelukast Versus Co Enzyme in Sepsis (NCT05293132) | Ain Shams University | 2022-02-01 |
| TocIlizumab in Late/Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients (NCT04561986) | Vastra Gotaland Region | 2022-02-01 |
| Pentoxifylline in Treatment of Patients With Nonalcoholic Steatohepatitis (NCT05284448) | Al-Azhar University | 2022-02-01 |
| Intravitreal and Intracameral DEX in NPDR (NCT06951087) | Affiliated Hospital of Nantong University | 2022-01-31 |
| IV Dexmedetomidine in the Duration of Spinal Anesthesia With Hyperbaric Bupivacaine: Double Blind Randomized Trial. (NCT05335655) | Hospital Central "Dr. Ignacio Morones Prieto" | 2022-01-31 |
| Efficacy and Safety of Adjuvant Docetaxel and Trastuzumab in Stage I HER2-positive Breast Cancer (NCT05189067) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-01-31 |
| PRF Versus Advanced PRF in Sinus Augmentation (NCT05134753) | Cairo University | 2022-01-30 |
| Erythropoietin to Improve Critical Care Patient Outcomes (NCT05080049) | University Hospital, Angers | 2022-01-28 |
| Cross-Over Study to Compare the Pharmacokinetics and Pharmacodynamics of LIB003 Process 1 and Process 2 Drug Product (NCT05234775) | LIB Therapeutics LLC | 2022-01-28 |
| Recurrent Abdominal Pain and Exocrine Pancreatic Insufficiency (NCT04231279) | Orlando Health, Inc. | 2022-01-28 |
| JT001 (VV116) for the Early Treatment of COVID-19 (NCT05242042) | Shanghai JunTop Biosciences Co., LTD | 2022-01-28 |
| Efficacy and Safety of Buspirone, Sustained-release Tablets, 15 mg in Patients With Autonomic Dysfunction Syndrome Accompanied by Vertigo (NCT05430217) | Valenta Pharm JSC | 2022-01-28 |
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (NCT05219968) | Lyra Therapeutics | 2022-01-27 |
| Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (NCT05136170) | Dompé Farmaceutici S.p.A | 2022-01-27 |
| A Study to Evaluate the Efficacy and Safety of AK102 Q6W in Patients With Hyperlipidemia (NCT05260411) | Akeso | 2022-01-26 |
| Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery (NCT05191745) | Jewish General Hospital | 2022-01-26 |
| Clinical Study of SHR-1701 Plus Chemotherapy as Perioperative Treatment in Subjects With Gastric Cancer (NCT05149807) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2022-01-26 |
| Use of a Disk of Amniotic Membrane (Visio-AMTRIX) in Postoperative Care After PKR (NCT05247658) | TBF Genie Tissulaire | 2022-01-25 |
| Phase 3 Clinical Study of AK112 for NSCLC Patients (NCT05184712) | Akeso | 2022-01-25 |
| A Study of TQB2450 Injection Plus Chemotherapy Followed by TQB2450 Plus Anlotinib Versus Tislelizumab Plus Chemotherapy Followed by Tislelizumab in the Treatment of First-line Non-squamous Non-small Cell Lung Cancer(NSCLC). (NCT05346952) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2022-01-25 |
| Caries Arresting in Primary Molar Teeth Using SDF VS ART (NCT05188846) | Ola Adel Abdelfadil Ahmed | 2022-01-25 |
| Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients (NCT06146478) | Blood Care Clinic | 2022-01-25 |
| A Study to Evaluate the Durability of Response and Safety of Nemolizumab for 24 Weeks in Participants With Prurigo Nodularis (NCT05052983) | Galderma R&D | 2022-01-24 |
| A Study of TAK-771 in Japanese People With Primary Immunodeficiency Diseases (PID) (NCT05150340) | Takeda | 2022-01-24 |
| Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD (NCT04759703) | Massachusetts General Hospital | 2022-01-24 |
| A Phase III Study in Subjects With Mild to Moderate Psoriasis. (NCT05249972) | Lipidor AB | 2022-01-24 |
| Effectiveness of iPRF Injections in Temporomandibular Joints Degeneration Management (NCT05214924) | Wroclaw Medical University | 2022-01-24 |
| Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia (NCT05184335) | Reviva Pharmaceuticals | 2022-01-24 |
| Heterologous Boost Immunization with an Aerosolised Ad5-nCoV After Two-dose Priming with an Inactivated SARS-CoV-2 Vaccine (NCT05204589) | Jiangsu Province Centers for Disease Control and Prevention | 2022-01-22 |
| Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen in Acute Myeloid Leukemia: Study Protocol for a Randomized Controlled Trial (NCT05382390) | Huihan Wang | 2022-01-21 |
| Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM (NCT05118776) | Ascletis Pharmaceuticals Co., Ltd. | 2022-01-21 |
| A Study to Learn About the Effect of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Risdiplam (ASCEND) (NCT05067790) | Biogen | 2022-01-21 |
| MISOBEST - Orally Misoprostol Solution (Cytotec®) Versus Orally Misoprostol as a Tablet (Angusta®) for Induction of Labor (NCT05424445) | Karolinska Institutet | 2022-01-21 |
| the Safety and Efficacy of Meplazumab in Patients With COVID-19 (NCT05113784) | Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd | 2022-01-21 |
| The INVIGORATE 2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis (NCT05234554) | Aldeyra Therapeutics, Inc. | 2022-01-21 |
| MITO 35B: Olaparib Beyond Progression Compared to Platinum Chemotherapy After Secondary Cytoreductive Surgery in Recurrent Ovarian Cancer Patients. (NCT05255471) | National Cancer Institute, Naples | 2022-01-21 |
| [18F]APN-1607 PET in Subjects With AD Compared to HC (NCT05542953) | APRINOIA Therapeutics | 2022-01-21 |
| Efficacy, Immunogenicity and Safety of Inactivated Vaccine (Coronavac) Against SARS-COV2 in Children and Adolescents (NCT05225285) | Federal University of Espirito Santo | 2022-01-21 |
| A Phase Ⅲ Efficacy and Safety Study of Hemay005 in Subjects With Moderate to Severe Plaque Psoriasis (NCT04839328) | Tianjin Hemay Pharmaceutical Co., Ltd | 2022-01-20 |
| Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis (NCT05369234) | Covenant Health Cancer Center | 2022-01-20 |
| Cognitive Effects of Adjuvant Vortioxetine in Early Schizophrenia (NCT04895488) | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 2022-01-20 |
| A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers (NCT05206370) | Achieve Life Sciences | 2022-01-20 |
| Randomization to Extend Stroke Intravenous ThromboLysis In Evolving Non-Large Vessel Occlusion With TNK (RESILIENT (NCT05199662) | Hospital Moinhos de Vento | 2022-01-20 |
| Evaluation of Effectiveness of ALBENDAZOLIVERMECTIN Coformulation vs ALBENDAZOLE for Treatment of Intestinal Worms (NCT05124691) | Barcelona Institute for Global Health | 2022-01-20 |
| Comparison Erect Spine in Cardiac Surgery (NCT04313959) | Instituto do Coracao | 2022-01-20 |
| KN046 in Subjects With Advanced Pancreatic Ductal Adenocarcinoma. (NCT05149326) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2022-01-20 |
| SPT-07A Injection in Patients With Acute Ischemic Stroke (AIS): A Phase III Clinical Trial (NCT05159947) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2022-01-20 |
| Efficacy and Safety of the Application of Local Anaesthetic in Spray to Repair of 1st- 2nd Perineal Lacerations (NCT05201313) | Azienda Sanitaria-Universitaria Integrata di Udine | 2022-01-20 |
| Study of the Safety and Efficacy of the Subunit Recombinant Tuberculosis Vaccine GamTBvac (NCT04975737) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2022-01-20 |
| A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease (NCT05197049) | Janssen Research & Development, LLC | 2022-01-19 |
| Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-III (NCT05141305) | Beijing Tiantan Hospital | 2022-01-19 |
| Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study) (NCT05133180) | Dompé Farmaceutici S.p.A | 2022-01-19 |
| Lokelma for RAAS Maximisation in CKD & Heart Failure. (NCT05004363) | St George's, University of London | 2022-01-19 |
| A Study of TAK-771 in Japanese Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and Multifocal Motor Neuropathy (MMN) (NCT05084053) | Takeda | 2022-01-19 |
| Tolerability, Safety and Immunogenicity Trial of the Flu-M Tetra Vaccine in Children (NCT05739474) | St. Petersburg Research Institute of Vaccines and Sera | 2022-01-19 |
| Thyroxine Treatment in Premature Infants With Intraventricular Hemorrhage (NCT03390530) | Albert Einstein College of Medicine | 2022-01-18 |
| This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer. (NCT05438810) | Ahon Pharmaceutical Co., Ltd. | 2022-01-18 |
| Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty (NCT05139030) | Pacira Pharmaceuticals, Inc | 2022-01-18 |
| Protecting Preterm Infants From Respiratory Tract Infections and Wheeze by Using Bacterial Lysates. (NCT05063149) | Franciscus Gasthuis | 2022-01-18 |
| Stem Cells in Spinal Cord Injury (NCT03935724) | Neuroplast | 2022-01-18 |
| A Study of Maribavir in Japanese People With Cytomegalovirus (CMV) Infection (NCT05137717) | Takeda | 2022-01-18 |
| Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular Cancer (NCT05244577) | Shi Yanxia | 2022-01-18 |
| Efficacy and Safety of Benralizumab in Patients With Eosinophilic Gastritis and/or Gastroenteritis (The HUDSON GI Study) (NCT05251909) | AstraZeneca | 2022-01-18 |
| Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy (NCT04889430) | Novartis Pharmaceuticals | 2022-01-17 |
| A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD) (NCT05195528) | Phathom Pharmaceuticals, Inc. | 2022-01-17 |
| Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older (NCT05153317) | Vertex Pharmaceuticals Incorporated | 2022-01-17 |
| JP-1366 20mg Versus Esomeprazole 40mg in Patients With Erosive Esophagitis (NCT05443984) | Onconic Therapeutics Inc. | 2022-01-17 |
| Camrelizumab, Apatinib Plus HAIC Versus Camrelizumab and Apatinib for HCC With Portal Vein Invasion: a Randomized Trial (NCT05198609) | Sun Yat-sen University | 2022-01-17 |
| Efficacy and Safety Assessment of Beltavac® With Polymerized Extract of HDM (NCT05395689) | Probelte Pharma S.L.U. | 2022-01-17 |
| OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD) (NCT04283227) | Orchard Therapeutics | 2022-01-17 |
| A Study of Camrelizumab in Combination With Chemotherapy Regimen Comparative Chemotherapy Regimen for Metastatic Triple-negative Breast Cancer (NCT05134194) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2022-01-17 |
| Study on Safety and Clinical Efficacy of AZVUDINE in Initial Stage COVID-19 Patients (SARS-CoV-2 Infected) (NCT05033145) | HRH Pharmaceuticals Limited | 2022-01-15 |
| A Safety and Efficacy Study of Remibrutinib in the Treatment of CSU in Japanese Adults Inadequately Controlled by H1-antihistamines (NCT05048342) | Novartis Pharmaceuticals | 2022-01-15 |
| Study Evaluating the Efficacy and Safety of AV5080 in Patients With Uncomplicated Influenza (NCT05093998) | Viriom | 2022-01-15 |
| Use of Corticosteroids in Third Molar Surgery (NCT05752305) | Universidad de Granada | 2022-01-15 |
| Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining (NCT07351370) | Dental School | 2022-01-15 |
| Probiotic Modulates Vaginal Microflora (NCT05302687) | Min-Tze LIONG | 2022-01-15 |
| of Sodium Glucose Cotransporter-2 Inhibitors on Metabolic, Hormonal and Clinical Parameters in PCO (NCT05601336) | Beni-Suef University | 2022-01-15 |
| A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06) (NCT05002127) | ALX Oncology Inc. | 2022-01-15 |
| An Open-Label Study of Apabetalone in Covid Infection (NCT04894266) | Resverlogix Corp | 2022-01-14 |
| A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003) (NCT05139017) | Merck Sharp & Dohme LLC | 2022-01-14 |
| A Study of GB491 in Combination With Letrozole in Patients With HR Positive and HER2 Negative Advanced Breast Cancer (NCT05851014) | Genor Biopharma Co., Ltd. | 2022-01-14 |
| Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17) (NCT05127954) | AbbVie | 2022-01-14 |
| A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF) (NCT05111145) | Vertex Pharmaceuticals Incorporated | 2022-01-14 |
| Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures (NCT05067634) | SK Life Science, Inc. | 2022-01-14 |
| Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17) (NCT05125302) | AbbVie | 2022-01-13 |
| Investigator Initiated Trial to Study Duobrii® Lotion in the Treatment of Mild Plaque Psoriasis in Adults (NCT05203315) | Austin Institute for Clinical Research | 2022-01-13 |
| Efficacy and Safety of Tralokinumab Administered by an Autoinjector in Adults and Adolescents With Moderate to Severe Atopic Dermatitis (INJECZTRA) (NCT05194540) | LEO Pharma | 2022-01-13 |
| Pharmacological and Behavioral Treatment After Bariatric Surgery (NCT05157698) | Yale University | 2022-01-13 |