| PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis (NCT04971720) | University of Alabama at Birmingham | 2022-02-18 |
| Study to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer (NCT04851613) | Laekna Limited | 2022-02-18 |
| Clinical Study of the Third Dose Immunization Schedule of COVID-19 Inactivated Vaccine, (Vero Cells) in Adults Aged 18 Years and Above (6 Months After Two Doses) (NCT05216484) | Chinese Academy of Medical Sciences | 2022-02-18 |
| Hydrocortisone and Fludrocortisone for Critical Illness-related Corticosteroid Insufficiency (NCT04404400) | Assistance Publique - Hôpitaux de Paris | 2022-02-17 |
| Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive (NCT05264506) | Organon and Co | 2022-02-17 |
| To Evaluate the Long-term Safety and Efficacy of HSK16149 in Chinese Patients With Peripheral Neuralgia (NCT05890053) | Haisco Pharmaceutical Group Co., Ltd. | 2022-02-17 |
| Study of Amcenestrant (SAR439859) Versus Tamoxifen for Patients With Hormone Receptor-positive (HR+) Early Breast Cancer, Who Have Discontinued Adjuvant Aromatase Inhibitor Therapy Due to Treatment-related Toxicity (NCT05128773) | Sanofi | 2022-02-17 |
| Emicizumab PUPs and Nuwiq ITI Study (NCT04030052) | Emory University | 2022-02-17 |
| Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis (NCT05248997) | Pfizer | 2022-02-17 |
| An Expanded Access Trial in Japan to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment Options (NCT05200247) | Boehringer Ingelheim | 2022-02-17 |
| A Study to Evaluate the Immunogenicity and Safety of Omicron Variant Vaccines in Comparison With mRNA-1273 Booster Vaccine for COVID-19 (NCT05249829) | ModernaTX, Inc. | 2022-02-16 |
| Surviving PEA in Roanoke (SPEAR) Study (NCT05283850) | Carol Bernier | 2022-02-16 |
| ACTIV-6: COVID-19 Study of Repurposed Medications - Arm D (Ivermectin 600) (NCT05894538) | Susanna Naggie, MD | 2022-02-16 |
| Ivermectin for Post Exposure Prophylaxis of Covid-19 (NCT05231603) | Clinical Research Centre, Malaysia | 2022-02-16 |
| Testing the Addition of Ixazomib/Placebo to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM Trial (NCT03941860) | National Cancer Institute (NCI) | 2022-02-16 |
| Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH III Trial) (NCT04448184) | Ottawa Hospital Research Institute | 2022-02-16 |
| Technology Supported High Intensity Training at Home for Persons With Chronic Low Back Pain (NCT05234008) | Hasselt University | 2022-02-15 |
| Vonoprazan Efficacy to Prevent Post Variceal Band Ligation Ulcer (NCT05227833) | Alexandria University | 2022-02-15 |
| Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC) (NCT05263206) | Sanofi | 2022-02-15 |
| Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH) (NCT05238519) | Essentia Health | 2022-02-15 |
| Efficacy and Safety of the Fixed-dose Combination Atorvastatin/Fenofibrate vs Atorvastatin in Patients With T2D and DLP. (NCT04882293) | Laboratorios Silanes S.A. de C.V. | 2022-02-15 |
| Effect of Glucuronosyltransferase (UGT) Genetic Variation on Pharmacokinetics of Empagliflozin (NCT05036421) | Ain Shams University | 2022-02-15 |
| Comparing TIVA Using Propofol or Dexmedetomidine Versus Sevoflurane During Anaesthesia of Children Undergoing Bone-Marrow Aspiration (NCT05636566) | Alexandria University | 2022-02-15 |
| Neighborhood Park Youth Sports Program Fee Waiver and Intensive Family Outreach (NCT05231837) | University of Minnesota | 2022-02-15 |
| Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy (NCT05157841) | Pacira Pharmaceuticals, Inc | 2022-02-15 |
| Bupivicain vs Bupivicain Plus Dexamethasone in ESP Block for Post-op Analgesia (NCT05277974) | Sheikh Zayed Medical College | 2022-02-15 |
| A Phase III Study to Evaluate the Efficacy and Safety of Penpulimab in the Relapsed and Refractory Classical Hodgkin's Lymphoma (NCT05244642) | Akeso | 2022-02-15 |
| Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis (NCT05138133) | AstraZeneca | 2022-02-15 |
| Haplo-PBSC+Cord vs Haplo-PBSC+BM for Hematological Malignancies Undergoing Allo-HSCT (NCT05290545) | Nanfang Hospital, Southern Medical University | 2022-02-15 |
| Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty (NCT05300685) | University of California, San Francisco | 2022-02-15 |
| Long-Term Safety, Efficacy, and Durability of EN3835 in the Treatment and Retreatment of Plantar Fibromatosis (NCT05254457) | Endo USA Inc., a Keenova Therapeutics Company | 2022-02-14 |
| Molar Sodium Lactate Filling in Severe Meningeal Hemorrhage (NCT04141371) | Centre Hospitalier Universitaire de Nice | 2022-02-14 |
| A Multicenter Study to Evaluate Safety and Immunogenicity of a Live-attenuated Chikungunya Vaccine in Adolescents (NCT04650399) | Butantan Institute | 2022-02-14 |
| A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients (NCT05126459) | Loma Linda University | 2022-02-14 |
| A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria (NCT05166161) | PTC Therapeutics | 2022-02-14 |
| A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT) (NCT04573023) | JCR Pharmaceuticals Co., Ltd. | 2022-02-14 |
| 177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer (NCT05204927) | Curium US LLC | 2022-02-14 |
| Safety and Immunogenicity of Live Attenuated Varicella Vaccine in Healthy Population Aged ≥13 Years Old (NCT05158777) | Shanghai Institute Of Biological Products | 2022-02-13 |
| A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer (NCT05141721) | Seattle Project Corporation | 2022-02-12 |
| Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis Intervention (NCT05241431) | University of Aarhus | 2022-02-12 |
| Efficacy and Safety of SmofKabiven Extra Nitrogen for Parenteral Nutrition in Patients Receiving Intensive Care (NCT05257031) | Fresenius Kabi | 2022-02-12 |
| Anti-Inflammatory Efficacy of Ginger Containing Dentifrice in the Control of Biofilm Induced Gingivitis (NCT05868200) | University of Baghdad | 2022-02-12 |
| A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP) (NCT05031780) | Agios Pharmaceuticals, Inc. | 2022-02-11 |
| Roll-over Study to Assess Safety of Lixivaptan in Participants With ADPKD Who Completed Study PA-ADPKD-303 (NCT05208866) | Palladio Biosciences | 2022-02-10 |
| The Effectiveness of a Caralluma Fimbriata Extract on Stress, Sleep and Neurotransmitters (NCT05232266) | RDC Clinical Pty Ltd | 2022-02-10 |
| Trial Evaluating the Efficacy and Safety of Patiromer in Chinese Subjects (NCT05136664) | Vifor Fresenius Medical Care Renal Pharma | 2022-02-10 |
| A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD) (NCT04779320) | Takeda | 2022-02-10 |
| The Impact of Thromboprophylaxis on Progression Free Survival of Patients With Advanced Pancreatic Cancer (NCT05178628) | Michalis Karamouzis | 2022-02-10 |
| DEB-TACE+HAIC vs. HAIC for Large HCC (NCT05263219) | Second Affiliated Hospital of Guangzhou Medical University | 2022-02-10 |
| All Japanese Population: Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma (NCT06956170) | GlaxoSmithKline | 2022-02-10 |
| Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Mild COVID-19 (NCT05783206) | National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia | 2022-02-10 |
| PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer (NCT05180734) | Shanghai Junshi Bioscience Co., Ltd. | 2022-02-10 |
| Donepezil Versus Non-drug Treatment in Alzheimer's Disease. (NCT04661280) | Assistance Publique - Hôpitaux de Paris | 2022-02-10 |
| Efficacy and Safety of Oxybutynin Versus Paroxetine in Aromatase Inhibitor-induced Vasomotor Symptoms (NCT05637671) | Cairo University | 2022-02-10 |
| Combining Aspirin With Ticagrelor or Cilostazol in Minor Stroke or TIA (NCT06591390) | Kafrelsheikh University | 2022-02-09 |
| Omega-3 Hydrogel and Prevention of Oral Mucositis (NCT05214495) | Basma Morsy | 2022-02-09 |
| Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer (NCT05171660) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-02-08 |
| Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) (NCT04978272) | Grant Dorsey, M.D, Ph.D. | 2022-02-08 |
| "MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome (NCT05305898) | Military Institute od Medicine National Research Institute | 2022-02-08 |
| GM1 Prophylaxis for Post-chemotherapy Cognitive Impairment in Patients With Early Operable Breast Cancer (NCT05239663) | Sun Yat-sen University | 2022-02-08 |
| Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management (NCT05243511) | Swing Therapeutics, Inc. | 2022-02-08 |
| A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive (NCT05173974) | HALEON | 2022-02-08 |
| Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER) (NCT05300672) | Azienda Usl di Bologna | 2022-02-08 |
| GENIFEM Trial: Postoperative Pain After Total Knee Arthroplasty (TKA) (NCT05156476) | Ziekenhuis Oost-Limburg | 2022-02-07 |
| Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations. (NCT05158387) | AstraZeneca | 2022-02-07 |
| Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease (NCT05202509) | NewAmsterdam Pharma | 2022-02-07 |
| A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer (NCT05221840) | AstraZeneca | 2022-02-07 |
| Safety and Immunogenicity of 2 Doses Versus 1 Dose of Acellular Pertussis Vaccines Containing Genetically-detoxified Pertussis Toxin in Young Adults Previously Primed With Acellular Pertussis Vaccines (NCT05193734) | University Hospital, Geneva | 2022-02-07 |
| Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome (NCT04718025) | Collegium Medicum w Bydgoszczy | 2022-02-07 |
| Long-term Extension Study to Evaluate MBA-P01 in Subjects With Moderate to Severe Glabellar Lines (NCT05321979) | Medytox Korea | 2022-02-07 |
| Fast Acute Sedation at Intensive Care vs. High-dose i.v. Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus (FAST-trial) (NCT05263674) | University of Southern Denmark | 2022-02-07 |
| Metal Panel Allergen Patch Test Study (NCT04500834) | Allerderm | 2022-02-07 |
| A Study to Evaluate and Compare the Efficacy and Safety of XZP-3621 Versus Crizotinib (NCT05204628) | Xuanzhu Biopharmaceutical Co., Ltd. | 2022-02-07 |
| Effects of Dry Needling With a Standard Exercise Programme on Pain and Quality of Life in Patients With Chronic Mechanical Neck Pain (NCT05220852) | Imam Abdulrahman Bin Faisal University | 2022-02-06 |
| Efficacy and Safety of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis (NCT04848688) | Jennifer Keiser | 2022-02-05 |
| The MUFFIN-PTS Trial (NCT03833024) | Sir Mortimer B. Davis - Jewish General Hospital | 2022-02-04 |
| Opioid Free Anesthesia in Total Hip Arthroplasty (NCT05072704) | CMC Ambroise Paré | 2022-02-03 |
| Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15) (NCT05173987) | Merck Sharp & Dohme LLC | 2022-02-03 |
| TXA Nebulization for the Treatment of Hemoptysis (NCT05648656) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2022-02-03 |
| A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures (NCT05076617) | UCB Biopharma SRL | 2022-02-03 |
| A Prevention Trial of Canakinumab in Subjects at High Risk for Lung Cancer (NCT05725343) | Mario Negri Institute for Pharmacological Research | 2022-02-03 |
| Neuro-inflammation and Post-infectious Fatigue in Individuals With and Without COVID-19 (NCT05371522) | Amsterdam UMC, location VUmc | 2022-02-03 |
| A Phase III Trial to Assess the Safety and Immunogenicity of a HIPRA's Candidate Booster Vaccination Against COVID-19. (NCT05246137) | Hipra Scientific, S.L.U | 2022-02-03 |
| Efficacy and Safety of Valerian Root Extract and Lavender Essential Oil Combination, Over 4 Weeks in Subjects With Sleep Complaints (NCT05194618) | University Hospital, Bordeaux | 2022-02-02 |
| A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOGAD) (NCT05063162) | UCB Biopharma SRL | 2022-02-02 |
| Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery (NCT05392634) | N.N. Petrov National Medical Research Center of Oncology | 2022-02-02 |
| A Study to Evaluate the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine in Healthy Non-pregnant Females From 9 to 49 Years of Age (NCT05169905) | GlaxoSmithKline | 2022-02-02 |
| A Study on the Immune Response and Safety of a Vaccine Against Herpes Zoster in Adults Aged 50 Years and Older in India (NCT05219253) | GlaxoSmithKline | 2022-02-02 |
| A Trial of Centanafadine Efficacy and Safety in Adolescents With Attention- Deficit/Hyperactivity Disorder (NCT05257265) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2022-02-02 |
| Treatment of Plantar Warts (NCT05198180) | Sohag University | 2022-02-01 |
| Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo. (NCT05586763) | Oman Medical Speciality Board | 2022-02-01 |
| Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer (NCT05050162) | NRG Oncology | 2022-02-01 |
| Zanubrutinib for HLH (NCT05320575) | Beijing Friendship Hospital | 2022-02-01 |
| Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure (NCT05962255) | Wroclaw Medical University | 2022-02-01 |
| A Study to Assess the Efficacy and Safety of Paricalcitol in the Treatment of Chronic Kidney Disease With Secondary Hyperparathyroidism (NCT04994080) | Chengdu Suncadia Medicine Co., Ltd. | 2022-02-01 |
| BAFF/IL-17 Bispecific Antibody Treatment in Subjects With Primary Sjogren's Syndrome (NCT04563195) | Matthew C. Baker | 2022-02-01 |
| TOtal Skin Electron Beam Therapy (Low-dose) for Tumor Clone Eradication in Early-stage Mycosis Fungoides (NCT05205902) | Assistance Publique - Hôpitaux de Paris | 2022-02-01 |
| Anti-emetic Prophylaxis With or Without Dexamethasone (NCT05242874) | Henan Cancer Hospital | 2022-02-01 |
| Use of Probiotics to Reduce Infections, Death and ESBL Colonisation (NCT04172012) | Haydom Lutheran Hospital | 2022-02-01 |
| Steroids for Early Treatment of Radiation Retinopathy (NCT03238157) | The Cleveland Clinic | 2022-02-01 |