| Phase 3, Randomized Study of Apremilast in Japanese Participants With Palmoplantar Pustulosis (PPP) (NCT05174065) | Amgen | 2022-03-08 |
| A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin (NCT05275400) | Eli Lilly and Company | 2022-03-08 |
| Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients (NCT05236647) | University Hospital, Akershus | 2022-03-08 |
| LONG-TERM EFFECTIVENESS AND SAFETY EVALUATION OF OCRELIZUMAB (NCT05210621) | Centre Hospitalier Universitaire de Nice | 2022-03-08 |
| An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia (NCT05304767) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2022-03-07 |
| Non-inferiority Trial on Treatments in Early COVID-19 (NCT05321394) | Azienda Ospedaliera Universitaria Integrata Verona | 2022-03-07 |
| EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease (NCT05261139) | Pfizer | 2022-03-07 |
| Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (NCT05052801) | Amgen | 2022-03-07 |
| A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer (NCT05132582) | Seagen, a wholly owned subsidiary of Pfizer | 2022-03-07 |
| Non-invasive Ventilation and Dex in Critically Ill Adults (NCT04878510) | St. Joseph's Healthcare Hamilton | 2022-03-07 |
| Effects of Modulators of Gluconeogenesis, Glycogenolysis and Glucokinase Activity (NCT05098470) | University of Alabama at Birmingham | 2022-03-07 |
| Low-Titer O Positive Whole Blood Versus Component Therapy for Emergent Transfusion in Trauma Patients (NCT05081063) | Loma Linda University | 2022-03-05 |
| To Evaluate HU-014 in the Treatment of Post Stroke Upper Limb (NCT05289921) | Huons Co., Ltd. | 2022-03-04 |
| Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy (NCT05273307) | University of California, San Francisco | 2022-03-04 |
| A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome (NCT05163314) | Takeda | 2022-03-04 |
| A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Japanese Participants With Eosinophilic Gastroenteritis (NCT05214768) | Celgene | 2022-03-04 |
| Neuroimaging Study of Dexmedetomidine-Induced Analgesia (NCT04656470) | Massachusetts General Hospital | 2022-03-04 |
| Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations (NCT05215340) | Daiichi Sankyo | 2022-03-04 |
| Effect of Probiotics Among Overweight and Obese Saudi Adults (NCT05667038) | King Saud University | 2022-03-03 |
| Phase III Clinical Study of NPB-01 in Patients With Autoimmune Encephalitis (NCT05177939) | Nihon Pharmaceutical Co., Ltd | 2022-03-03 |
| Frontline Clinician Psilocybin Study (NCT05163496) | University of Washington | 2022-03-03 |
| Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC (NCT04973306) | Shanghai Zhongshan Hospital | 2022-03-02 |
| REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke patiEnts (NCT04667078) | Fondation Ophtalmologique Adolphe de Rothschild | 2022-03-02 |
| PSMA PET Additive Value for Prostate Cancer Diagnosis in Men With Negative/Equivocal MRI (NCT05154162) | Peter MacCallum Cancer Centre, Australia | 2022-03-02 |
| This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer. (NCT05439499) | Ahon Pharmaceutical Co., Ltd. | 2022-03-02 |
| Tc 99m Tilmanocept Imaging for Early Prediction of Anti-TNFα Therapy Response in Moderate to Severe Active RA (NCT05246280) | Navidea Biopharmaceuticals | 2022-03-02 |
| The Efficacy and Safety of ZR2 Versus R-miniCHOP in the Treatment of Unfit or Frail de Novo Diffuse Large B-cell Lymphoma Patients Aged Older Than or Equal to 70 Years (NCT05179733) | Ruijin Hospital | 2022-03-02 |
| GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG (NCT05153226) | DKMS gemeinnützige GmbH | 2022-03-02 |
| The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy (NCT06115460) | Ain Shams University | 2022-03-01 |
| Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children (NCT05233683) | King Saud University | 2022-03-01 |
| Randomized Controlled Trial of Hydroxychloroquine Combined With Low-dose Corticosteroid in Pulmonary Sarcoidosis (NCT05247554) | Assistance Publique - Hôpitaux de Paris | 2022-03-01 |
| VAH Versus VA for Salvage Therapy of R/R-AML (NCT05457361) | Nanfang Hospital, Southern Medical University | 2022-03-01 |
| Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis (NCT05078827) | Encube Ethicals Pvt. Ltd. | 2022-03-01 |
| Evaluation of The Effect of Loratadine Versus Diosmin/Hesperidin Combination on Vinca Alkaloids Induced Neuropathy (NCT05243706) | Ain Shams University | 2022-03-01 |
| A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer (NCT05243550) | UroGen Pharma Ltd. | 2022-03-01 |
| MetfOrmin BenefIts Lower Extremities With Intermittent Claudication (NCT05132439) | VA Office of Research and Development | 2022-03-01 |
| Amoxicillin-clavulanate Alone or in Combination With Ciprofloxacin in Low-Risk Febrile Neutropenic Adult Patients: A Prospective, Double-blind, Randomized, Non-Inferiority Multicenter, Phase III Clinical Trial. (NCT04698057) | Poitiers University Hospital | 2022-03-01 |
| A Dosing Study of Hyperbaric Oxygen Therapy (HBOT) on Epigenetic Aging (NCT05297019) | TruDiagnostic | 2022-03-01 |
| Effect of New Oral Treatment for Hepatitis C Virus on Seminal Parameters (NCT05616598) | Benha University | 2022-03-01 |
| An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103) (NCT05243680) | GlaxoSmithKline | 2022-03-01 |
| Silver Diamine Fluoride(SDF) Versus SDF Combined With Sodium Fluoride Varnish in the Arrest of Early Childhood Caries (NCT05642494) | Alexandria University | 2022-03-01 |
| Mirabegron, Propevirine, Solifenacin for Treatment of Lower Urinary Tract Symptoms During Intravesical BCG Instillation (NCT05490082) | Mansoura University | 2022-03-01 |
| Prevention of C.Difficile Infections With Oral Vancomycine in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant (NCT05256693) | Assistance Publique - Hôpitaux de Paris | 2022-03-01 |
| Lacosamide in Neonatal Status Epilepticus (NCT05291455) | Sherief Abd-Elsalam | 2022-03-01 |
| Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC (NCT05852990) | Instituto Nacional de Cancerologia de Mexico | 2022-03-01 |
| Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women (NCT06036576) | Al-Kindy College of Medicine | 2022-03-01 |
| Australian Phase 2b Study to Assess Effect of Dose Interval on Spikogen Covid-19 Vaccine (NCT05148871) | Vaxine Pty Ltd | 2022-03-01 |
| Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC (NCT05199818) | Xiamen LP Pharmaceutical Co., Ltd | 2022-03-01 |
| Utidelone Plus Capecitabine Versus Taxane Plus Capecitabine in HER2-negative Locally Advanced or Metastatic Breast Cancer (NCT05172518) | Sun Yat-sen University | 2022-03-01 |
| Alflutinib Versus Alflutinib Plus Chemotherapy for NSCLC (NCT05209256) | The First Affiliated Hospital of Henan University of Science and Technology | 2022-03-01 |
| Effectiveness of Vitamin C Supplementation in Treatment of Rickets (NCT05310760) | Cairo University | 2022-03-01 |
| Study Evaluating Neoadjuvant Immunotherapy Increasing CD8+ Cell Infiltration in Advance Gastric Adenocarcinoma (NCT05270824) | Fujian Medical University | 2022-03-01 |
| A Study to Compare JL14002 to Lucentis® in Subjects With Wet Age-related Macular Degeneration (wAMD) (NCT07389577) | Jecho Biopharmaceuticals Co., Ltd. | 2022-03-01 |
| Effectiveness of Port Site Bupivacaine Injection in Postoperative Pain Reduction After Lap. Chole (NCT05264805) | Hamdard University | 2022-03-01 |
| Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery (NCT05849597) | University of Novi Sad | 2022-03-01 |
| Inhaled Amikacin in Preventing AECOPD (NCT05213507) | Shanghai Zhongshan Hospital | 2022-03-01 |
| Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast Cancer (NCT04973930) | New York State Psychiatric Institute | 2022-03-01 |
| Efficacy and Safety of Iguratimod in Patients With Hand Osteoarthritis (ESIGO) (NCT05216757) | Peking University People's Hospital | 2022-03-01 |
| A Clinical Trial to Evaluate the Efficacy and Safety of Anotinib Hydrochloride Capsule Combined With Epirubicin Hydrochloride Versus Placebo Combined With Epirubicin Hydrochloride in First-line Treatment of Advanced Soft Tissue Sarcoma (NCT05121350) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2022-03-01 |
| Venetoclax + Decitabine vs. "7+3" Induction Chemotherapy in Young AML (NCT05177731) | Chen Suning | 2022-03-01 |
| Cyclin Dependant Kinase 4/6 (CDK4/6) Inhibitors as a Second Line Treatment in Metastatic Breast Cancer Patients (NCT05670054) | Mansoura University | 2022-03-01 |
| Efficacy and Safety of CUSA-081 in the Restoration of Dysfunctional Central Venous Access Device (CVAD) Functionality (NCT03992443) | Chiesi Farmaceutici S.p.A. | 2022-02-28 |
| Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects (NCT05156398) | Pfizer | 2022-02-28 |
| Efficacy and Safety of 9MW0813 in Subjects With Diabetic Macular Edema (NCT05324774) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2022-02-28 |
| Efficacy and Safety of Ambervin® and Standard Therapy in Hospitalized Patients With COVID-19 (NCT05656495) | Promomed, LLC | 2022-02-28 |
| Rituximab EfFicacy IN MyasthEnia Gravis (REFINE) (NCT05868837) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2022-02-28 |
| The Efficacy and Safety of JS002 PFS and AI in Patients With Primary Hypercholesterolemia and Mixed Hyperlipidemia (NCT05532800) | Shanghai Junshi Bioscience Co., Ltd. | 2022-02-28 |
| Apomorphine Effects on Pain in Parkinson's Disease (NCT04879134) | University of Calgary | 2022-02-28 |
| Acute Normovolemic Hemodilution in Complex Cardiac Surgery (NCT05049590) | University of California, Los Angeles | 2022-02-28 |
| Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children (NCT05026749) | University of Alabama at Birmingham | 2022-02-27 |
| Phase 3 Study to Evaluate Immunogenicity and Safety of BBV154 Booster Dose (NCT05567471) | Bharat Biotech International Limited | 2022-02-26 |
| A Study of SHR-1701 Plus Platinum-containing Chemotherapy With or Without BP102 (Bevacizumab) as First-line Treatment in Cervical Cancer (NCT05179239) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2022-02-26 |
| A Study to Evaluate the Safety and Immunogenicity of Ad5-nCoV and Ad5-nCoV-IH in CoronaVac Immunized Children and Adolescents (NCT05169008) | CanSino Biologics Inc. | 2022-02-25 |
| A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen (NCT05185843) | Ionis Pharmaceuticals, Inc. | 2022-02-25 |
| Chidamide Combined With Exemestane (+/- Goserelin) Versus Neoadjuvant Chemotherapy in Patients of Stage II-III HR-positive/HER2-negative Breast Cancer (NCT05253066) | Shengjing Hospital | 2022-02-25 |
| A Study to Assess Adverse Events of Intramuscular AGN-151586 Injection in Adult Participants With Glabellar Lines (NCT05248893) | AbbVie | 2022-02-25 |
| Triumeq in Amyotrophic Lateral Sclerosis (NCT05193994) | Macquarie University, Australia | 2022-02-24 |
| A Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Disorder. (NCT05279313) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2022-02-24 |
| Anti-inflammatory Drug Algorithm for COVID-19 Home Treatment (NCT05249790) | Mario Negri Institute for Pharmacological Research | 2022-02-24 |
| Study in Adult Patients With Moderate to Severe Asthma (NCT04886999) | Chiesi Farmaceutici S.p.A. | 2022-02-24 |
| Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation (NCT05196503) | University Hospital, Strasbourg, France | 2022-02-23 |
| Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden (NCT05230901) | University Medical Center Goettingen | 2022-02-23 |
| Immunogenicity and Safety of the SpikoGen COVID-19 Vaccine in Children Aged 5 to <12 Years and 12 to <18 Years Compared With Adults Aged 18 to 40 Years (NCT05231590) | Cinnagen | 2022-02-23 |
| Efficacy of Simvastatin in Alcoholic Liver Fibrosis (NCT04971577) | Anna Cruceta | 2022-02-22 |
| A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents (NCT05102591) | University of Calgary | 2022-02-22 |
| A Phase III Randomized, Modified Double-blind, Multi-centric, Comparative Study, to Evaluate the Non-inferiority of Immunogenicity and Safety of Hillchol® (BBV131)to Shanchol™ Along With Lot-to-lot Consistency of Hillchol®(BBV131). (NCT05507229) | Bharat Biotech International Limited | 2022-02-22 |
| A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE) (NCT05259917) | KalVista Pharmaceuticals, Ltd. | 2022-02-22 |
| RAE (Realize, Analyze, Engage) (NCT05227339) | ContinueYou, LLC | 2022-02-22 |
| Trial to Study the Efficacy and Safety of BEJO Red Ginger in COVID-19 Patients With Mild Symptoms (NCT05277155) | Research Center for Chemistry, National Research and Innovation Agency of Indonesia | 2022-02-22 |
| HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose (NCT05136885) | Merit E. Cudkowicz, MD | 2022-02-21 |
| A Study of the Effects of AB-205 in Patients With Lymphoma Undergoing Autologous Hematopoietic Cell Transplantation (NCT05181540) | Angiocrine Bioscience | 2022-02-21 |
| A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection (NCT05120349) | AstraZeneca | 2022-02-21 |
| Effect of Lithium in Patients With Autism Spectrum Disorder and Phelan-McDermid Syndrome (SHANK3 Haploinsufficiency) (NCT04623398) | Assistance Publique - Hôpitaux de Paris | 2022-02-21 |
| Setrusumab vs Placebo for Osteogenesis Imperfecta (NCT05125809) | Ultragenyx Pharmaceutical Inc | 2022-02-21 |
| Treat of Functional Ovarian Cysts by Compare Between Cocs and Progesterone Only Pills (NCT05244811) | Sohag University | 2022-02-20 |
| Immuno-bridging and Broadening Study of a Whole, Inactivated COVID-19 Vaccine BBV152 in Healthy Adults (NCT05258669) | Ocugen | 2022-02-20 |
| Postoperative Analgesic Effectiveness of Bupivacaine With and Without Dexmedetomidine in Patients With Abdominal Surgery (NCT06531603) | Sahiwal medical college sahiwal | 2022-02-20 |
| Investigating the Anti-inflammatory Effects of Frondanol in Adults With Inflammatory Bowel Disease (NCT05194007) | Mohammed Bin Rashid University of Medicine and Health Sciences | 2022-02-19 |
| Efficacy, Immunogenicity, and Safety of V503 in Chinese Males (V503-052) (NCT05285826) | Merck Sharp & Dohme LLC | 2022-02-18 |
| A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC (NCT05211895) | AstraZeneca | 2022-02-18 |