| Booster Study of SpikoGen COVID-19 Vaccine (NCT05542862) | Vaxine Pty Ltd | 2022-09-07 |
| Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer (NCT05425940) | Exelixis | 2022-09-07 |
| Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain (NCT05054179) | University of British Columbia | 2022-09-07 |
| A Study to Assess Adverse Events and Effectiveness of Intradermally Injected JUVÉDERM® VOLITE™ Gel Filler in Adult Participants in China With Fine Lines Around the Mouth (NCT05454033) | AbbVie | 2022-09-07 |
| Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease (NCT04905693) | United Therapeutics | 2022-09-06 |
| A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation (NCT05557409) | Axsome Therapeutics, Inc. | 2022-09-06 |
| Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial (NCT05334368) | GlaxoSmithKline | 2022-09-06 |
| A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Non-Erosive Reflux Disease (NCT05587322) | Braintree Laboratories | 2022-09-06 |
| A Study Evaluating Toripalimab Injection Combined With Standard Chemotherapy as a First-line Treatment for Locally Advanced or Metastatic Urothelial Carcinoma (NCT04568304) | Shanghai Junshi Bioscience Co., Ltd. | 2022-09-06 |
| A Prospective Clinical Trial to Evaluate the Efficacy and Safety of Neurotropic B-Vitamins in Clinically Diagnosed Peripheral Sensory Polyneuropathy of Different Etiologies. (NCT05619328) | Procter and Gamble | 2022-09-06 |
| Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001 (NCT05508594) | Cessatech A/S | 2022-09-05 |
| A Study to Evaluate Safety and Efficacy of Elagolix in Patients With Moderate to Severe Endometriosis-Associated Pain (NCT05648669) | Qilu Pharmaceutical (Hainan) Co., Ltd. | 2022-09-04 |
| A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2 (NCT05331885) | Aridis Pharmaceuticals, Inc. | 2022-09-02 |
| Astaxanthin for Management of Inflammation in Knee Osteoarthritis (NCT05138549) | Prisma Health-Midlands | 2022-09-02 |
| A Phase III Study of Oral Sudapyridine (WX-081) Tablets in Rifampicin-Resistant Pulmonary Tuberculosis Patients (NCT05824871) | Shanghai Jiatan Pharmatech Co., Ltd | 2022-09-02 |
| A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma (NCT05505734) | Bond Avillion 2 Development LP | 2022-09-02 |
| A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants (NCT05452070) | Allergan | 2022-09-02 |
| Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy (NCT05545800) | Xiangya Hospital of Central South University | 2022-09-01 |
| Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01) (NCT05443854) | Assistance Publique - Hôpitaux de Paris | 2022-09-01 |
| Henagliflozin in Patients With Atrial Fibrillation (NCT05252624) | Beijing Anzhen Hospital | 2022-09-01 |
| Optimization of Cervical Nodal CTV for Early and Medium Stage NPC (NCT05145660) | Yi Junlin | 2022-09-01 |
| Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia (NCT05615727) | The University of Hong Kong | 2022-09-01 |
| ComPAS Low-WAZ RCT Mali (NCT05248516) | International Rescue Committee | 2022-09-01 |
| Effect of Gui-Lu-Er-Xian-Jiao-Wan on Intradialytic Hypotension (NCT05517993) | Chang Gung Memorial Hospital | 2022-09-01 |
| A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery (NCT05550350) | EyePoint Pharmaceuticals, Inc. | 2022-09-01 |
| The API-CALF Study: Apixaban to Treat Calf Vein Thrombosis (NCT04981327) | University Hospital, Geneva | 2022-09-01 |
| GLS-010 Monotherapy Versus Chemotherapy in Patients With Relapsed or Refractory Classical Hodgkin's Lymphoma (R/R cHL) (NCT05518318) | Guangzhou Gloria Biosciences Co., Ltd. | 2022-09-01 |
| Applicability of 3D-HDRA in Patients With Primary Liver Cancer: A Randomized Controlled Trial (NCT05701436) | Zhujiang Hospital | 2022-09-01 |
| The Effect of a New Antioxidant Combination (ASTED) on Moderate to Severe Thyroid Eye Disease (NCT02422368) | Iran University of Medical Sciences | 2022-09-01 |
| Peroperative Administration of Tranexamic Acid in Roux-en-Y Gastric Bypass and One-anastomosis Gastric Bypass (NCT05464394) | Franciscus Gasthuis | 2022-09-01 |
| SGLT2 Inhibitors in Non-Diabetic CKD: Effects on Vascular Calcification and Anemia (NCT07344922) | Mansoura University | 2022-09-01 |
| Comparison of Analgesic Efficacy of Ultrasound Guided Rhomboid Intercostal Block Versus Serratus Anterior Plane Block for Mastectomy Surgery (NCT05518292) | Mansoura University | 2022-09-01 |
| Cognitive Behavioural Therapy Versus Psychoeducation for Perinatal Anxiety (NCT05510752) | St. Joseph's Healthcare Hamilton | 2022-09-01 |
| LiST Plus PRP Injection Therapy vs LiST Monotherapy for ED Treatment (NCT05366504) | Institute for the Study of Urological Diseases, Greece | 2022-09-01 |
| Anticoagulation-free VV ECMO for Acute Respiratory Failure (NCT04273607) | Damian Ratano | 2022-09-01 |
| Early Salvage Therapy for Patients With Advanced Features for Biochemical Relapse After Radical Prostatectomy for Localized Prostate Carcinoma In Correlation With Supposed Molecular-genetic Parameters of Higher Aggressiveness (NCT05232578) | General University Hospital, Prague | 2022-09-01 |
| Methadone for 'Adenocarcinopathic' Pain Treatment (NCT05325164) | Ottawa Hospital Research Institute | 2022-09-01 |
| Ultrasound Guided Quadratus Lumborum Block Versus Transversus Abdominis Plane Block as Postoperative Analgesia in Patients Undergoing Abdominal Cancer Surgery. (NCT05533424) | Mansoura University | 2022-09-01 |
| Blood Flow and Blood Pressure Investigation in Down Syndrome (NCT05528549) | University of Illinois at Chicago | 2022-09-01 |
| Safety Outcomes Post Kidney Biopsy - Randomized Clinical Evaluation of Efficacy of Desmopressin (NCT05467033) | Medical University of Bialystok | 2022-09-01 |
| Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9 (NCT05580341) | Shanghai Zerun Biotechnology Co.,Ltd | 2022-09-01 |
| A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery (2) (NCT05550363) | EyePoint Pharmaceuticals, Inc. | 2022-09-01 |
| A Study to Evaluate the Efficacy and Safety of HCP2102 in Essential Hypertension Patients (NCT05450601) | Hanmi Pharmaceutical Company Limited | 2022-09-01 |
| Pac-12 Test of the Effectiveness of Bodies in Motion in Reducing Disordered Eating and Body Image Concerns (NCT05864287) | University of Arizona | 2022-09-01 |
| Study of Ruxolitinib Cream in Adolescents With Atopic Dermatitis (NCT05456529) | Incyte Corporation | 2022-09-01 |
| Paediatric Arteriopathy Steroid Aspirin Project (NCT03249844) | Centre Hospitalier Universitaire de Saint Etienne | 2022-09-01 |
| Open-Label Study of AXS-07 for the Acute Treatment of Migraine in Adults With a Prior Inadequate Response to an Oral CGRP Inhibitor (EMERGE) (NCT05550207) | Axsome Therapeutics, Inc. | 2022-08-31 |
| Sulfadoxine-pyrimethamine Plus Dihydroartemisinin-piperaquine for Intermittent Preventive Treatment in Pregnancy (NCT05426434) | Menzies School of Health Research | 2022-08-31 |
| A Clinical Study of rhPTH(1-84) Treatment in Japanese Participants With Chronic Hypoparathyroidism (NCT03878953) | Shire | 2022-08-31 |
| A Study Comparing Treatment With Lutetium[177Lu] Oxodotreotide Injection to Octreotide LAR in Patients With GEP-NETs (NCT05459844) | Sinotau Pharmaceutical Group | 2022-08-31 |
| A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (NCT05552326) | Ionis Pharmaceuticals, Inc. | 2022-08-31 |
| A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared With CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid (NCT05292586) | Chiesi Farmaceutici S.p.A. | 2022-08-31 |
| Baricitinib in Patients With Relapsing or naïve Dermatomyositis (NCT04972760) | Assistance Publique - Hôpitaux de Paris | 2022-08-31 |
| Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076) (NCT05281471) | Genelux Corporation | 2022-08-31 |
| Clemastine Fumarate as Remyelinating Treatment in Internuclear Ophthalmoparesis and Multiple Sclerosis (NCT05338450) | Amsterdam UMC, location VUmc | 2022-08-30 |
| Effects of Triptorelin When Given Every 6-months Under the Skin to Adult Males With Cancer in the Prostate (NCT05458856) | Ipsen | 2022-08-30 |
| ABNCoV2 Vaccine in Adult Subjects Previously Vaccinated for SARS-CoV-2 (NCT05329220) | Bavarian Nordic | 2022-08-30 |
| Evaluation of dAroLutamide Addition to anDrogen Deprivation Therapy and radIatioN Therapy in Newly Diagnosed Prostate Cancer With Pelvic Lymph Nodes Metastases (NCT05116475) | Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie | 2022-08-30 |
| A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis (NCT05083182) | Janssen Research & Development, LLC | 2022-08-30 |
| A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (NCT05271409) | Hoffmann-La Roche | 2022-08-30 |
| Phase III Study of TS-142 in Patients with Insomnia (NCT05453136) | Taisho Pharmaceutical Co., Ltd. | 2022-08-30 |
| A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE) (NCT05514535) | Novo Nordisk A/S | 2022-08-29 |
| Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (NCT04979806) | Wockhardt | 2022-08-28 |
| Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy (NCT05521152) | Kasr El Aini Hospital | 2022-08-28 |
| CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus (NCT05356403) | Cara Therapeutics, Inc. | 2022-08-26 |
| Efficacy and Safety of RTX-GRT7039 in Adult Subjects With Knee Osteoarthritis (NCT05248386) | Grünenthal GmbH | 2022-08-26 |
| Research on the Correlation Between Organoid Drug Sensitivity Testing and Precise Treatment of Gastrointestinal Tumors (NCT06332716) | Jianjun Yang,MD | 2022-08-26 |
| A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (NCT05418673) | Biogen | 2022-08-26 |
| A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery (NCT05425056) | Vascular Therapies, Inc. | 2022-08-26 |
| A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) (NCT05500222) | Madrigal Pharmaceuticals, Inc. | 2022-08-26 |
| A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥2 Years to <12 Years of Age With Uncontrolled Chronic Spontaneous Urticaria (CSU) (LIBERTY-CSU CUPIDKids) (NCT05526521) | Sanofi | 2022-08-25 |
| ACTIV-6: COVID-19 Study of Repurposed Medications - Arm E (Fluvoxamine 100) (NCT05894564) | Susanna Naggie, MD | 2022-08-25 |
| 18F-Fluciclovine PET Imaging for Detecting High Grade Glioma Recurrence After Radiochemotherapy (NCT05479136) | Nicole Hill | 2022-08-24 |
| A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD) (NCT05814159) | Swedish Orphan Biovitrum | 2022-08-24 |
| A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery (NCT05156983) | Takeda | 2022-08-24 |
| Multicenter Study in Postmenopausal Women With Osteoporosis, ALVOBOND (NCT05395091) | Alvotech Swiss AG | 2022-08-23 |
| Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis (NCT05515029) | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 2022-08-23 |
| The Efficacy of Botulinum Toxin vs. Corticosteroid for the Treatment of Refractory Plantar Fasciitis (NCT05367271) | Western Institute for Veterans Research | 2022-08-23 |
| Study on an Investigational Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Administered as a 5- and/or 10-year Booster Doses in Children and Adolescents Vaccinated 5 or 10 Years Earlier as Toddlers (NCT04936685) | Sanofi Pasteur, a Sanofi Company | 2022-08-23 |
| A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1) (NCT05511363) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2022-08-23 |
| Efficacy and Safety of DPI-386 Nasal Gel for the Prevention of Nausea and Vomiting Associated With Motion (NCT05548270) | Repurposed Therapeutics, Inc. | 2022-08-23 |
| Open-label Extension Study of Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Lupus Nephritis (NCT05232864) | Novartis Pharmaceuticals | 2022-08-22 |
| The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms (NCT05367089) | Maastricht University Medical Center | 2022-08-22 |
| Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers (NCT05539872) | Amphastar Pharmaceuticals, Inc. | 2022-08-22 |
| Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials (NCT05492578) | Sanofi | 2022-08-22 |
| Study of Dexycu in Treating Intraocular Inflammation (NCT06429306) | Ocumension Therapeutics (Shanghai) Co., Ltd | 2022-08-22 |
| Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery (NCT05516953) | Tanta University | 2022-08-22 |
| Chemotherapy vs Chemoradiotherapy for Post-operative Endometrial Cancer Patients With P53-mutation (NCT05489848) | Fudan University | 2022-08-20 |
| A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany (NCT05305664) | Novartis Pharmaceuticals | 2022-08-19 |
| Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar Spine (NCT05516992) | Spine BioPharma, Inc | 2022-08-19 |
| A Clinical Study to Evaluate the Efficacy and Safety of SIM0417 Orally Co-Administered With Ritonavir in Symptomatic Adult Participants With Mild to Moderate COVID-19 (NCT05506176) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2022-08-19 |
| A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia (NCT05458128) | Harmony Biosciences Management, Inc. | 2022-08-19 |
| A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy (NCT05414175) | Bristol-Myers Squibb | 2022-08-19 |
| Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis (NCT05374590) | argenx | 2022-08-18 |
| A Study of MIL62 in Patients With Neuromyelitis Optica Spectrum Disorder (NMOSD) (NCT05314010) | Beijing Mabworks Biotech Co., Ltd. | 2022-08-18 |
| Study to Assess Adverse Events and Change in Disease Activity of Oral Cariprazine Capsules in Adult Participants With Schizophrenia (NCT05368558) | AbbVie | 2022-08-18 |
| A Single-arm Clinical Trial of IMGN853 in Chinese Adult Patients With Platinum-resistant, Epithelial Ovarian Cancer (NCT05622890) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2022-08-18 |
| Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A (NCT05970679) | Daewon Pharmaceutical Co., Ltd. | 2022-08-17 |
| Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch (NCT04892654) | Chelsea and Westminster NHS Foundation Trust | 2022-08-17 |
| EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs (NCT05429476) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-08-17 |