| Bioequivalence Study of Tiotropium 18 μg Inhalation Powder, Hard Capsule With Spiriva®Handihaler® 18 μg Inhalation Powder, Hard Capsule in Patients With Chronic Obstructive Pulmonary Disease (COPD) (NCT05986591) | Xiromed LLC | 2022-08-17 |
| A Study to Evaluate the Efficacy and Safety of SHR0302 in Patients With Non-Radiographic Axial Spondyloarthritis (NCT05324631) | Jiangsu HengRui Medicine Co., Ltd. | 2022-08-16 |
| Study to Demonstrate the Efficacy and Safety of Secukinumab up to 224 Weeks in Subjects With Active Peripheral Spondyloarthritis (pSpA). (NCT05206591) | Novartis Pharmaceuticals | 2022-08-16 |
| Saypha® VOLUME Lidocaine for Midface Augmentation (NCT05386030) | Croma-Pharma GmbH | 2022-08-16 |
| Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (NCT05502341) | Gilead Sciences | 2022-08-16 |
| The Effect of Oral Nanocurcumin as an Adjuvant Therapy for Anogenital Warts: Evaluation of Clinical Improvement, NFĸB, IFN-γ, and FOXP3+TReg From Lesions Tissue (NCT06281353) | Indonesia University | 2022-08-16 |
| Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (NCT05387707) | Cara Therapeutics, Inc. | 2022-08-16 |
| Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study (NCT05384431) | Exerkine Corporation | 2022-08-15 |
| A Phase 3b/4 Randomised Trial of 3 Doses of Protein-based Covid-19 Vaccine (SpikoGen) (NCT05279456) | Vaxine Pty Ltd | 2022-08-15 |
| Research Study Investigating How Well Semaglutide Works in People From Thailand and South Korea Living With Obesity (NCT04998136) | Novo Nordisk A/S | 2022-08-15 |
| Safety of Administering Isoniazid to SLE Patients to Prevent TB (NCT06618573) | Universitas Padjadjaran | 2022-08-15 |
| Sapylin Versus Dexamethasone Inhalation for CCRT-Induced Oral Mucositis in Nasopharyngeal Carcinoma (NCT07327216) | Affiliated Hospital of Guangdong Medical University | 2022-08-15 |
| ONO-4059 Study in Patients With Steroid-resistant Pemphigus (NCT06696716) | Ono Pharmaceutical Co., Ltd. | 2022-08-15 |
| The Effect of Erythropoietin in the Treatment of Scleral Necrosis (NCT05476042) | Shahid Beheshti University of Medical Sciences | 2022-08-14 |
| A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy (NCT05463744) | Eli Lilly and Company | 2022-08-12 |
| A Study to Evaluate the Safety, Tolerability, Immunogenicity, and Lot Consistency of V116 in Adults 18 to 49 Years of Age (V116-004, STRIDE-4) (NCT05464420) | Merck Sharp & Dohme LLC | 2022-08-12 |
| A Randomised, Multi-centre, Double-blind, Phase 3 Study to Observe the Effectiveness, Safety and Tolerability of Molnupiravir Compared to Placebo Administered Orally to High-risk Adult Outpatients With Mild COVID-19 Receiving Local Standard of Care in South Africa (NCT05459532) | University of Witwatersrand, South Africa | 2022-08-12 |
| Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets (NCT05317858) | InSightec | 2022-08-12 |
| Colchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3) (NCT05439356) | Beijing Tiantan Hospital | 2022-08-11 |
| Analyzing the Relationship Between Speed Propofol is Given and Low Blood Pressure (NCT05415436) | University of Toledo | 2022-08-11 |
| A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections (NCT05462756) | Eli Lilly and Company | 2022-08-11 |
| Safety and Effectiveness of Juveena™ Hydrogel System Following Transcervical Gynecologic Procedures (TCGP) At High-Risk for Intrauterine Adhesions (NCT05394662) | Rejoni Inc. | 2022-08-11 |
| A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow (NCT05330325) | Novo Nordisk A/S | 2022-08-10 |
| A Study on the Long-term Efficacy, Safety and Persistence of Immune Response of a Vaccine Against Herpes Zoster in Older Adults (NCT05371080) | GlaxoSmithKline | 2022-08-10 |
| A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension (NCT05495061) | Santen Pharmaceutical Co., Ltd. | 2022-08-09 |
| Efficacy and Safety Study of Rimegepant for Migraine Prevention in Japanese Subjects (Japan Only) (NCT05399485) | Pfizer | 2022-08-09 |
| Pimavanserin for the Treatment of Irritability Associated With Autism Spectrum Disorder (NCT05523895) | ACADIA Pharmaceuticals Inc. | 2022-08-09 |
| Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma (NCT05398263) | AstraZeneca | 2022-08-09 |
| Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars (NCT05484401) | Reckitt Benckiser Healthcare (UK) Limited | 2022-08-09 |
| Efficacy and Safety of Antimicrobial Durations Treatment of Infections Associated With Osteosynthesis Material (NCT05294796) | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 2022-08-09 |
| A Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyposis （CROWNS-2） (NCT05436275) | Keymed Biosciences Co.Ltd | 2022-08-09 |
| Efficacy and Safety Study of Rimegepant for the Acute Treatment of Migraine in Japanese Subjects (Japan Only) (NCT05399459) | Pfizer | 2022-08-09 |
| Clinical Trial to Evaluate the Safety and Efficacy of IN-C006 Peri Inj. Compared With RPN301 (NCT05337228) | HK inno.N Corporation | 2022-08-09 |
| Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure (NCT05355974) | Wright State University | 2022-08-09 |
| A Study of TACE Combined With Camrelizumab Plus Rivoceranib (Apatinib) in Patients With Incurable Hepatocellular Carcinoma (NCT05320692) | Jiangsu HengRui Medicine Co., Ltd. | 2022-08-09 |
| Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis (NCT04991935) | Celgene | 2022-08-09 |
| A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension (NCT05503901) | Santen Pharmaceutical Co., Ltd. | 2022-08-08 |
| Pediatric Dose Optimization for Seizures in Emergency Medical Services (NCT05121324) | Stanford University | 2022-08-08 |
| Study of a Single Intramuscular Dose of Nirsevimab in the Prevention of Hospitalizations Due to Respiratory Syncytial Virus (RSV) Infection in Healthy Term and Preterm Infants During the First Year of Life (NCT05437510) | Sanofi Pasteur, a Sanofi Company | 2022-08-08 |
| Evaluation of Triple Therapy Using Magnetic Resonance Imaging in Asthma (NCT04651777) | Dr. Grace Parraga | 2022-08-08 |
| A Clinical Trial of Quadrivalent Influenza Vaccine in Healthy Subjects Aged 6 to 35 Months (NCT05245552) | Sinovac Biotech Co., Ltd | 2022-08-08 |
| Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer (NCT05254171) | Panbela Therapeutics, Inc. | 2022-08-08 |
| The Possible Efficacy and Safety of L-carnitine and Biotin as Adjunctive Therapies in Children With Moderate Persistent Asthma (NCT05632549) | Tanta University | 2022-08-08 |
| Short-course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer (NCT05484024) | Chinese Academy of Medical Sciences | 2022-08-06 |
| A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer (NCT05388669) | Janssen Research & Development, LLC | 2022-08-05 |
| The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa (NCT05413148) | TC Erciyes University | 2022-08-05 |
| A Study to Evaluate the Safety and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections (NCT05544916) | Valenta Pharm JSC | 2022-08-05 |
| Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient (NCT04833816) | Assistance Publique Hopitaux De Marseille | 2022-08-05 |
| NPC-06 to Pain Associated With Acute Herpes Zoster (NCT05480553) | Nobelpharma | 2022-08-05 |
| Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High Cholesterol (NCT07564726) | Celltrion Pharm, Inc. | 2022-08-05 |
| DSUVIA Early Evaluation of Pain Trial (NCT05288348) | Frank Guyette | 2022-08-05 |
| A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery (NCT05528172) | Kowa Research Institute, Inc. | 2022-08-04 |
| A Trial of SHR-A1811versus Pyrotinib in Combination With Capecitabine in HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subjects Previously Treated With Trastuzumab and Taxane (NCT05424835) | Jiangsu HengRui Medicine Co., Ltd. | 2022-08-04 |
| A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031) (NCT05442775) | Cytokinetics | 2022-08-04 |
| Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma (NCT05304585) | Children's Oncology Group | 2022-08-04 |
| An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15) (NCT05477524) | Pfizer | 2022-08-04 |
| Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (NCT05349214) | Novartis Pharmaceuticals | 2022-08-04 |
| Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment (NCT05261399) | AstraZeneca | 2022-08-03 |
| A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole (NCT05178862) | Scynexis, Inc. | 2022-08-03 |
| A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD (NCT05357989) | Annovis Bio Inc. | 2022-08-03 |
| A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes (NCT05478252) | Novo Nordisk A/S | 2022-08-03 |
| Evaluation of Rifaximin SSD for Delaying Encephalopathy Decompensation in Patients With Cirrhosis (NCT05297448) | Bausch Health Americas, Inc. | 2022-08-03 |
| A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer) (NCT05306340) | Genentech, Inc. | 2022-08-03 |
| Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction (NCT05110001) | University of California, San Francisco | 2022-08-03 |
| A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19 (NCT05305547) | Shionogi | 2022-08-03 |
| Daily Chlorexidine Bath for Health Care Associated Infection Prevention (NCT05485051) | Hospital do Coracao | 2022-08-03 |
| Letrozole as Maintenance Therapy for Post-surgical Endometrial Cancer Patients With NSMP (NCT05454358) | Fudan University | 2022-08-02 |
| A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma (NCT05732805) | Biocad | 2022-08-02 |
| SPI-1005 for the Treatment of Meniere's Disease (NCT04677972) | Sound Pharmaceuticals, Incorporated | 2022-08-02 |
| Oral Vancomycin Vs Placebo in the Prevention of Recurrence of Clostridioides Difficile's Infection (NCT05320068) | Julia Orígüen | 2022-08-02 |
| A Study to Compare Nivolumab Administered Subcutaneously vs Intravenous in Melanoma Participants Following Complete Resection (NCT05297565) | Bristol-Myers Squibb | 2022-08-02 |
| Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease (NCT05477563) | Vertex Pharmaceuticals Incorporated | 2022-08-02 |
| DIalysis Symptom COntrol-Pruritus Outcome Trial (NCT05180968) | University of Manitoba | 2022-08-02 |
| Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females (NCT05461573) | Insud Pharma | 2022-08-02 |
| Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (NCT05047172) | University of Florida | 2022-08-02 |
| Robot-assisted Partial Nephrectomy With and Without Mixed Reality (REALITATEM Study) (NCT06903260) | Hospital Moinhos de Vento | 2022-08-01 |
| Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study) (NCT05345639) | University Hospital, Angers | 2022-08-01 |
| A Study Assessing the Interchangeability Between TRS003 and Bevacizumab® For CRC (NCT05378867) | Zhejiang Teruisi Pharmaceutical Inc. | 2022-08-01 |
| Comparison Of Dexmedetomidine & Ketamine For Control Of Shivering In Vaginal Hysterectomy Under Spinal Anesthesia (NCT05481281) | Hamdard University | 2022-08-01 |
| Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars (NCT05348824) | Cairo University | 2022-08-01 |
| The Efficacy of Chemotherapy Combined With Immunocheckpoint Inhibitors in Advanced Biliary Malignancies (NCT05487443) | First People's Hospital of Hangzhou | 2022-08-01 |
| A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Doublet in Small Cell Lung Cancer (NCT05566041) | EpicentRx, Inc. | 2022-08-01 |
| A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1) (NCT05463731) | Eli Lilly and Company | 2022-08-01 |
| Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy (NCT04939987) | Wake Forest University Health Sciences | 2022-08-01 |
| A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment (NCT05133531) | Regeneron Pharmaceuticals | 2022-08-01 |
| The Postoperative Radiotherapy in N1 Breast Cancer Patients (NCT05440149) | Seoul National University Hospital | 2022-08-01 |
| Efficacy and Safety Study of the Fixed-dose Combination of Olmesartan + Indapamide When Compared to the Isolated Drugs in the Treatment of Hypertension. (NCT05110898) | Brainfarma Industria Química e Farmacêutica S/A | 2022-08-01 |
| Efficacy and Safety of Magnólia Nasal Gel in the Treatment of Allergic Rhinitis (NCT04670653) | EMS | 2022-08-01 |
| Peri-Operative Magnesium Infusion to Prevent Atrial Fibrillation Evaluated. (NCT05669417) | HagaZiekenhuis | 2022-08-01 |
| Efficacy and Safety Study of Ibuprofen Gel Compared to Placebo in the Treatment of Acute Musculoskeletal Pain (NCT05013567) | Brainfarma Industria Química e Farmacêutica S/A | 2022-08-01 |
| Tranexamic Acid for Alloplastic Breast Reconstruction (NCT04918589) | McMaster University | 2022-08-01 |
| Effect of GH on the Blastocyst Euploid Rate in AMA Patients (NCT05447208) | ShangHai Ji Ai Genetics & IVF Institute | 2022-08-01 |
| Adjuvant Sintilimab for Locally Advanced Esophageal Squamous Cell Carcinoma (NCT05495152) | Henan Cancer Hospital | 2022-08-01 |
| Doravirine and Weight Gain in Antiretroviral Naive (NCT05457530) | Prism Health North Texas | 2022-08-01 |
| An Observer-blind, Cohort Randomized, Exploratory Phase 3 Study to Evaluate the Safety and Immunogenicity of Recombinant Covid-19 Vaccine, mRNA Covid-19 Vaccine and Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine as 4th Dose in Individuals Primed/ Boosted With Various Regimens (NCT05470803) | D'Or Institute for Research and Education | 2022-08-01 |
| Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension (NCT04039464) | Johns Hopkins University | 2022-08-01 |
| Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy (NCT05369793) | Tanta University | 2022-08-01 |
| Topical Tranexamic Acid for Bilateral Breast Reduction Surgery (NCT04918576) | McMaster University | 2022-08-01 |
| Efficacy and Safety of Atenas Association in the Treatment of Type II Diabetes Mellitus and Hypertension (NCT05144360) | EMS | 2022-08-01 |
| Study to Assess Efficacy and Safety of Treamid for Patients With Reduced Exercise Tolerance After COVID-19 (NCT05516550) | PHARMENTERPRISES LLC | 2022-08-01 |