| Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical Remission (NCT05380453) | Novartis Pharmaceuticals | 2022-09-29 |
| Immunogenicity Trial of 3 Influenza Vaccines (NCT05479370) | Tan Tock Seng Hospital | 2022-09-29 |
| Clinical Trial to Evaluate the Efficacy and Safety of D064 and D701 Combination Therapy (NCT05526703) | Chong Kun Dang Pharmaceutical | 2022-09-28 |
| PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction (NCT05555290) | AstraZeneca | 2022-09-28 |
| Treating Immuno-metabolic Depression With Anti-inflammatory Drugs (NCT05415397) | Amsterdam UMC, location VUmc | 2022-09-28 |
| The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin (NCT05505994) | Daewoong Pharmaceutical Co. LTD. | 2022-09-28 |
| A Study to Assess the Safety of Budesonide/Glycopyrronium/Formoterol Fumarate With a Next-Generation Propellant in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (NCT05573464) | AstraZeneca | 2022-09-27 |
| A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis (NCT05503264) | Hoffmann-La Roche | 2022-09-27 |
| Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor (NCT06190782) | Fudan University | 2022-09-27 |
| OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects (NCT05583474) | Otsuka Beijing Research Institute | 2022-09-27 |
| Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin and Metformin (NCT05504239) | Handok Inc. | 2022-09-27 |
| A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease (NCT05347095) | Janssen-Cilag Ltd. | 2022-09-27 |
| A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE (NCT05171075) | Anthos Therapeutics, Inc. | 2022-09-27 |
| Empagliflozin for New On-set Heart Failure Study Regardless of Ejection Fraction (NCT05556044) | Chinese University of Hong Kong | 2022-09-27 |
| A Study to Evaluate Safety, Efficacy, Pharmacokinetics, and Immunogenicity of Test Pertuzumab (ZRC-3277, Cadila Healthcare Ltd.,) (NCT05283837) | Zydus Lifesciences Limited | 2022-09-26 |
| Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee (NCT05449132) | Grünenthal GmbH | 2022-09-26 |
| Comparing Platelet Rich Plasma and Corticosteroid for Military & Civilian Patients With Glenohumeral Osteoarthritis (NCT05160441) | Walter Reed National Military Medical Center | 2022-09-26 |
| Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage (NCT05168839) | Centre Hospitalier Universitaire de Besancon | 2022-09-26 |
| Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy (NCT05536297) | Astellas Pharma Global Development, Inc. | 2022-09-26 |
| Use of Crohn's Disease Exclusion Diet on Top of Standard Therapy Versus Standard Therapy Alone in Unstable Pediatric Crohn's Disease Patients. (NCT04777656) | Assistance Publique - Hôpitaux de Paris | 2022-09-26 |
| Assessment of Rituximab Therapeutic Response Versus Conventional Treatment (NCT05553496) | Ain Shams University | 2022-09-25 |
| Evaluation of Protective Effect of Activated Charcoal and Probiotic Against Progression of Chronic Kidney Disease (NCT05540431) | Waleed Khaild Rahman Kareem Al-kabi | 2022-09-25 |
| Effectiveness of IV Vitamin C in Reducing Oxidative Stress Associated With Free Flap Surgery (NCT05327348) | University of Malaya | 2022-09-25 |
| Analyzing the Pharmacodynamic Substances and the Effects of Yiqihuayu Decotion for Acute Ischemic Stroke (PHYSIS) (NCT05560152) | Ying Gao | 2022-09-25 |
| Effects and Safety of Sacubitril/Valsartan on Refractory Hypertension (NCT05545059) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2022-09-24 |
| Effect of Time-of-Day (ToD) for Immunochemotherapy on PFS in NSCLC (NCT05549037) | Hunan Province Tumor Hospital | 2022-09-23 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 When Administered Concomitantly With Influenza Vaccine in Adults 50 Years of Age or Older (V116-005, STRIDE-5) (NCT05526716) | Merck Sharp & Dohme LLC | 2022-09-23 |
| QL1706 Plus Chemotherapy±Bevacizumab for the First-Line Treatment of Persistent, Recurrent or Metastatic Cervical Cancer (NCT05446883) | Qilu Pharmaceutical Co., Ltd. | 2022-09-23 |
| A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children (NCT05543616) | BioNTech SE | 2022-09-23 |
| Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (NCT05327114) | Janssen Research & Development, LLC | 2022-09-23 |
| A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD (NCT05431088) | Pfizer | 2022-09-22 |
| A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD) (NCT05518149) | Janssen Research & Development, LLC | 2022-09-22 |
| Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial) (NCT05601700) | Ente Ospedaliero Ospedali Galliera | 2022-09-22 |
| Study of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Follicular Lymphoma (NCT05371093) | Kite, A Gilead Company | 2022-09-22 |
| Assessment of the Number of Missing Tooth Surfaces and the Molecular Findings on the Outcomes of Vital Pulp Therapy Using Two Calcium Silicate Materials (NCT06787742) | Suez Canal University | 2022-09-21 |
| EGFR-mutated Lung Cancer in Randomized Investigator-Initiated Study (NCT06486142) | Region Skane | 2022-09-21 |
| Clinical Study of HR20013 for Injection in Patients With Malignant Solid Tumors (NCT05509634) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2022-09-21 |
| A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo (NCT05485805) | Bayer | 2022-09-21 |
| A Study to Prove Non-inferior Immunogenicity of Grippol Quadrivalent Compared to Grippol Plus (NCT06385821) | NPO Petrovax | 2022-09-21 |
| Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery (NCT04870073) | Hamilton Health Sciences Corporation | 2022-09-21 |
| Cholecalciferol Comedication in IBD - the 5C-study (NCT04991324) | University Hospital, Basel, Switzerland | 2022-09-21 |
| A Prospective, Randomized, Investigator-blinded, Parallel, Multi-center, Phase 3 Trial (NCT05670470) | Taejoon Pharmaceutical Co., Ltd. | 2022-09-21 |
| A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (NCT05519085) | Celgene | 2022-09-20 |
| One vs Two Weeks Treatment for H.Pylori Eradication A RANDOMIZED NON-INFERIORITY PLACEBO CONTROLLED TRIAL (NCT05728424) | Aga Khan University | 2022-09-20 |
| IH Convidecia as Second Booster Dose Against Breakthrough Infections (NCT05517642) | CanSino Biologics Inc. | 2022-09-20 |
| Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma (NCT05409066) | Genmab | 2022-09-20 |
| Comparison Between Bupivacaine With and Without Fentanyl in Reducing Pain During Cesarean Delivery Under Spinal Anaesthesia (NCT05491187) | Tribhuvan University Teaching Hospital, Institute Of Medicine. | 2022-09-20 |
| Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes (NCT04011020) | Throne Biotechnologies Inc. | 2022-09-20 |
| The Implementation of Pre-exposure Prophylaxis of Injectable Cabotegravir (NCT05515770) | Evandro Chagas National Institute of Infectious Disease | 2022-09-20 |
| Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial) (NCT05358535) | University of Texas Southwestern Medical Center | 2022-09-19 |
| PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620 (NCT05456503) | University of Pennsylvania | 2022-09-19 |
| Clinical Trial to Evaluate the Efficacy and Safety of JP-1366 in Patients With Gastric Ulcer (NCT05448001) | Onconic Therapeutics Inc. | 2022-09-19 |
| Study Comparing Trifarotene Cream, 0.005% To AKLIEF ® (Trifarotene 0.005% Cream) In The Treatment Of Acne Vulgaris (NCT05550337) | Teva Pharmaceuticals USA | 2022-09-19 |
| Phase 2b/3 Study of ABX464 in Moderate to Severe Active Crohn's Disease Patients (NCT03905109) | Abivax S.A. | 2022-09-19 |
| Physiotherapy Intervention for Migraine Symptoms (NCT05741775) | Universiti Tunku Abdul Rahman | 2022-09-18 |
| A Study to Describe the Safety and Immunogenicity of 20vPnC in Infants in India and Taiwan (NCT05512819) | Pfizer | 2022-09-16 |
| Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology (NCT05206955) | Mayo Clinic | 2022-09-16 |
| A Study of SII Yellow Fever Vaccine to Compare Safety and Immunogenicity With STAMARIL® In Healthy Infants (NCT05447377) | Serum Institute of India Pvt. Ltd. | 2022-09-16 |
| Elective Level Ib Irradiation in Nasopharyngeal Carcinoma Patients Based on the International Guidelines (NCT05519956) | Fujian Cancer Hospital | 2022-09-16 |
| Effect of Mesenchymal Stem Cells in Primary Knee Osteoarthritis (NCT05783154) | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 2022-09-16 |
| EMpagliflozin to PREvent worSening of Left Ventricular Volumes and Systolic Function After Myocardial Infarction (NCT05020704) | NHS Greater Glasgow and Clyde | 2022-09-16 |
| Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee (NCT05377489) | Grünenthal GmbH | 2022-09-15 |
| A Open-label Study to Assess the Long-term Safety of Difamilast Ointment 1% in Mild to Moderate Atopic Dermatitis (NCT05571943) | Acrotech Biopharma Inc. | 2022-09-15 |
| Short Against Long Antibiotic Therapy for Infected Orthopedic Sites (NCT05499481) | Balgrist University Hospital | 2022-09-15 |
| A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy (NCT05450692) | AstraZeneca | 2022-09-15 |
| IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department (NCT05304442) | Baylor College of Medicine | 2022-09-15 |
| Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis (NCT05415137) | aTyr Pharma, Inc. | 2022-09-15 |
| Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery (NCT05502380) | Balgrist University Hospital | 2022-09-15 |
| A Study to Evaluate D-0502 in Subjects With ER+ Her2- Locally Advanced or Metastatic Breast Cancer (NCT06954961) | InventisBio Co., Ltd | 2022-09-15 |
| Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) (NCT05289700) | University Hospital, Geneva | 2022-09-15 |
| Dapagliflozin With or Without Spironolactone for HFpEF (NCT05676684) | Universidade do Porto | 2022-09-15 |
| Pregabalin Versus Gabapentin Opioid Sparing Effect in Discectomy (NCT05539924) | Research Institute of Ophthalmology, Egypt | 2022-09-15 |
| Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia Induction Related Hypotension (NCT05497700) | Brugmann University Hospital | 2022-09-15 |
| Research Trial Assessing the Immunogenicity and Safety of Three Meningococcal B Vaccine Strategies Among Patients With Asplenia. (NCT04166656) | Assistance Publique - Hôpitaux de Paris | 2022-09-15 |
| Evaluate the Efficacy and Safety of FB2001 in Hospitalized Patients With Moderate to Severe COVID-19 (BRIGHT Study) (NCT05445934) | Frontier Biotechnologies Inc. | 2022-09-14 |
| A Study of mRNA-1010 Seasonal Influenza Vaccine in Adults 50 Years Old and Older (NCT05566639) | ModernaTX, Inc. | 2022-09-14 |
| A Study to Compare Efficacy and Safety of CT-P47 and RoActemra in Patients With Rheumatoid Arthritis (NCT05489224) | Celltrion | 2022-09-14 |
| SARS-CoV-2 and Acetylsalicylic Acid (SARA) (NCT05073718) | Barcelona Institute for Global Health | 2022-09-14 |
| The Efficacy of Neoadjuvant Chemoradiotherapy in Comparison With Neoadjuvant Chemotherapy in Patients With Resectable Squamous Cell Esophageal Cancer (NCT05547529) | Blokhin's Russian Cancer Research Center | 2022-09-14 |
| A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus (NCT05531565) | Biogen | 2022-09-13 |
| Niraparib vs Niraparib Plus Bevacizumab in Patients With Platinum/Taxane-based Chemotherapy in Advanced Ovarian Cancer (NCT05009082) | AGO Study Group | 2022-09-13 |
| Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2 (NCT04628026) | University of Ulm | 2022-09-13 |
| A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis (NCT05528510) | Janssen Research & Development, LLC | 2022-09-13 |
| A Study to Evaluate the Long-term Safety of TAK-771 in Japanese Primary Immunodeficiency Disease (PID) Participants (NCT05513586) | Takeda | 2022-09-13 |
| A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT05057494) | AstraZeneca | 2022-09-12 |
| The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder (NCT05415865) | Herlev and Gentofte Hospital | 2022-09-12 |
| The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics (NCT06534450) | Dobri Kiprov | 2022-09-12 |
| Left Atrium Reservoir Function Modulation in Patients With Atrial Fibrillation: Digoxin Versus Beta Blocker (NCT05540600) | University of Monastir | 2022-09-12 |
| Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes (NCT05416580) | University of Banja Luka | 2022-09-12 |
| A Study to Evaluate a Modified RNA Vaccine Against Influenza in Adults 18 Years of Age or Older (NCT05540522) | Pfizer | 2022-09-12 |
| Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure (NCT05392764) | Juntendo University | 2022-09-10 |
| A Phase II/III Study of Efficacy and Safety of SHR7280 Tablets in Subjects With Menorrhagia With Uterine Fibroids (NCT05442827) | Jiangsu HengRui Medicine Co., Ltd. | 2022-09-10 |
| Efficacy and Safety of YW17 (Laronidase-CinnaGen) Compared to Aldurazyme® in MPS I Patients (NCT06406153) | Cinnagen | 2022-09-10 |
| Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial (NCT05738681) | Mahidol University | 2022-09-09 |
| A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT (NCT05613023) | Institute of Cancer Research, United Kingdom | 2022-09-09 |
| Comparing the Perioperative Analgesic Effect of Two Different Volumes of Local Anesthetic Solution in Erector Spinae Plane Block in Patients Undergoing Modified Radical Mastectomy (NCT05813158) | Cairo University | 2022-09-09 |
| Lidocaine for Pessary Check Pain Reduction (NCT05493735) | University of South Florida | 2022-09-08 |
| A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer (NCT05042375) | Jiangsu HengRui Medicine Co., Ltd. | 2022-09-08 |
| Study of Tecovirimat for Human Mpox Virus (NCT05534984) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-09-08 |
| Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation (NCT05243797) | European Myeloma Network B.V. | 2022-09-08 |