| VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma (NCT06570889) | Professor Klaus Bønnelykke | 2024-12-20 |
| The Role of Levosimendan as Inotropic Agent in Acute Aluminum Phosphide-induced Cardiotoxicity (NCT06478667) | Ain Shams University | 2024-12-20 |
| A Clinical Study to Evaluate the Efficacy, Tolerability, and Safety of Bempedoic Acid (NCT06780410) | Gan & Lee Pharmaceuticals. | 2024-12-20 |
| A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component) (NCT06708286) | CanSino Biologics Inc. | 2024-12-20 |
| A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (NCT06775379) | Xenon Pharmaceuticals Inc. | 2024-12-20 |
| Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium (NCT06624592) | Mayo Clinic | 2024-12-20 |
| Assessment of Short Immunotherapy After Radical Surgery of High-risk Malignant Melanoma (NCT06488482) | Uppsala University | 2024-12-19 |
| Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction (NCT06736574) | Cytokinetics | 2024-12-19 |
| Integrated Pharmacokinetics (PK)/Efficacy, Safety, and Immunogenicity Study to Demonstrate Similarity of JPB898, a Proposed Biosimilar to Nivolumab, to Opdivo® in Combination With Yervoy® (NCT06587451) | Sandoz | 2024-12-19 |
| Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology (NCT06856525) | Y. Michael Shim, MD | 2024-12-19 |
| Study of 18F-Florastamin PET/CT Imaging in Patients With Suspected Recurrence of Prostate Cancer (NCT06754085) | HTA Co., Ltd. | 2024-12-19 |
| Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement (NCT06766630) | Weiliang Shen, Ph.D., M.D. | 2024-12-19 |
| Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN) (NCT06696443) | Vertex Pharmaceuticals Incorporated | 2024-12-18 |
| A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy (NCT06742190) | argenx | 2024-12-18 |
| Study of a 4-Dose Regimen of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age (NCT06736041) | Sanofi Pasteur, a Sanofi Company | 2024-12-18 |
| GBS-NN/NN2 (50 µg of Each Fusion Protein [GBS-NN and GBS-NN2] in Combination With 500 µg Aluminum as Alhydrogel®) Given With and Without the Tdap Vaccine in Healthy Non-pregnant Women 18 to 49 Years of Age (NCT06494475) | Minervax ApS | 2024-12-17 |
| Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia (NCT06020495) | Assistance Publique - Hôpitaux de Paris | 2024-12-17 |
| The Comparative Efficacy of Standard Treatment Plus Ribavirin vs Standard Treatment Alone in Preventing Clinically Significant Hemorrhage in Patients With Dengue Fever (NCT06744777) | Khyber Medical University Peshawar | 2024-12-17 |
| "A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder" (NCT06564818) | Cybin IRL Limited | 2024-12-17 |
| A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma (NCT06581406) | Replimune, Inc. | 2024-12-17 |
| A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer (NCT06612151) | MediLink Therapeutics (Suzhou) Co., Ltd. | 2024-12-17 |
| Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation (NCT07092618) | AgelessRx | 2024-12-17 |
| Study Comparing Tapinarof Cream 1% To VTAMA ® (Tapinarof Cream 1%) In the Treatment of Plaque Psoriasis (NCT06742957) | Teva Pharmaceuticals USA | 2024-12-17 |
| Addition of Thoracic Consolidation Radiotherapy to the Maintenance Immunotherapy for ES-SCLC (STONE-001) (NCT06719336) | Anhui Shi, MD | 2024-12-16 |
| Assess the Efficacy of OM-89 vs Placebo in Reducing Antibiotic Consumption Associated With the Treatment of Urinary Tract Infections in Patients With Neurogenic Bladder (NCT06588010) | Centre Hospitalier Universitaire Dijon | 2024-12-16 |
| Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy (NCT06763328) | City of Hope Medical Center | 2024-12-16 |
| A Study of Maribavir in Chinese Adults With Cytomegalovirus (CMV) Infections (NCT06439342) | Takeda | 2024-12-16 |
| A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM) (NCT06679101) | GlaxoSmithKline | 2024-12-16 |
| A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer (NCT06747338) | Shanghai JMT-Bio Inc. | 2024-12-16 |
| Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function. (NCT05879276) | Central Hospital, Nancy, France | 2024-12-16 |
| A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD) (NCT06548100) | Regeneron Pharmaceuticals | 2024-12-16 |
| A Study to Evaluate Safety and Effectiveness of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Improvement of Mid-Face Volume (NCT06734351) | AbbVie | 2024-12-16 |
| Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART) (NCT06317051) | Kirby Institute | 2024-12-16 |
| Analgesic Effects of Intranasal Diclofenac Sodium, Ibuprofen, and Paracetamol in Pediatric Tonsillectomy Cases (NCT06731556) | Bezmialem Vakif University | 2024-12-15 |
| Xuanhuang Runtong Tablet in the Treatment of Constipation (Yin-deficiency Type) (NCT06740422) | Beijing Hospital of Traditional Chinese Medicine | 2024-12-15 |
| A Study of XY03-EA Tablets in the Treatment of Acute Ischemic Stroke (NCT06755944) | Shijiazhuang Yiling Pharmaceutical Co. Ltd | 2024-12-15 |
| Comparative Study Between Antihyperlipidemic Agents in Treatment of Cardiovascular Diseases (NCT07313124) | Beni-Suef University | 2024-12-15 |
| A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in 7 to 17 Year Olds (NCT06700148) | CanSino Biologics Inc. | 2024-12-14 |
| Efficacy, Safety, and Immunogenicity of the Bivalent Inactivated Enterovirus Vaccine (Vero Cell) (NCT06734832) | Sinovac Biotech Co., Ltd | 2024-12-13 |
| Study to Evaluate the Efficacy and Safety of VGR-R01 Gene Therapy in Patients With Bietti Crystalline Dystrophy (NCT06699108) | Shanghai Vitalgen BioPharma Co., Ltd. | 2024-12-13 |
| An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment (NCT06675955) | Hoffmann-La Roche | 2024-12-13 |
| Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents (NCT06745557) | CUTISS AG | 2024-12-13 |
| Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (NCT06608927) | Arcus Biosciences, Inc. | 2024-12-13 |
| Efficacy of Baloxavir Against Influenza in Hospitalized Patients: The INFLUENT Study (INpatients inFLUENza Treatment) (NCT06653569) | Dre Pauline Vetter | 2024-12-13 |
| Normobaric Oxygen in AIS Transferred for EVT (NCT06666764) | Capital Medical University | 2024-12-13 |
| A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma (NCT06664619) | Teva Branded Pharmaceutical Products R&D LLC | 2024-12-12 |
| A Study of Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer (NCT06686576) | Qilu Pharmaceutical Co., Ltd. | 2024-12-12 |
| Study Comparing Therapy for Advanced Relapsed/Refractory Multiple Myeloma With and Without Dexamethasone (NCT06561854) | Assistance Publique - Hôpitaux de Paris | 2024-12-12 |
| Study of Fruquintinib Plus Sintilimab for Treatment of Advanced Endometrial Cancer (NCT06584032) | Hutchmed | 2024-12-12 |
| A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy (NCT06750094) | Janssen Research & Development, LLC | 2024-12-12 |
| Long-term Efficacy of Once Daily Versus Twice Daily Aspirin in High-risk MPN Patients With Aspirin Resistance (NCT06740916) | Siriraj Hospital | 2024-12-12 |
| A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE) (NCT06716606) | GlaxoSmithKline | 2024-12-12 |
| Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain (NCT06500455) | NRG Oncology | 2024-12-12 |
| Continuous ESP Block in Patients Undergoing CABG Surgery. (NCT07666178) | Instituto do Coracao | 2024-12-12 |
| Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer (NCT06632327) | Alliance for Clinical Trials in Oncology | 2024-12-11 |
| Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1) (NCT06999902) | Praxis Precision Medicines | 2024-12-11 |
| Melatonin fOr CHronic bAck Pain (The MOCHA Trial) (NCT06476392) | Odense University Hospital | 2024-12-11 |
| A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis. (NCT05421858) | Basilea Pharmaceutica | 2024-12-11 |
| Open-Label Extension of EryDex Study IEDAT-04-2022 (NCT06664853) | Quince Therapeutics S.p.A. | 2024-12-11 |
| A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis (NCT06588855) | Hoffmann-La Roche | 2024-12-11 |
| A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage) (NCT06741228) | Definium Therapeutics US, Inc. | 2024-12-11 |
| Comparing Prophylactic Intravenous Pethidine and Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section (NCT06775431) | Alexandria University | 2024-12-10 |
| Tacrolimus Minimization in Kidney Transplant Recipients Selected According to the AGORA Algorithm for Their Low Immunological Risk and Medium-term Graft Failure (NCT06235892) | Nantes University Hospital | 2024-12-10 |
| Fexofenadine as Adjuvant Therapy in Parkinson Disease (NCT06785298) | Tanta University | 2024-12-10 |
| Novel Approaches to the Treatment of Hypothyroidism (NCT06731764) | UConn Health | 2024-12-10 |
| Phase III Clinical Trial of Lot-to-lot Consistency of Recombinant Herpes Zoster Vaccine (CHO Cell). (NCT06654700) | MAXVAX Biotechnology Limited Liability Company | 2024-12-09 |
| Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia (NCT06597019) | Novartis Pharmaceuticals | 2024-12-09 |
| Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute) (NCT06691984) | Amgen | 2024-12-09 |
| A Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine and Influenza Combination Vaccine (NCT06291857) | Novavax | 2024-12-09 |
| A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease (NCT06679140) | Pfizer | 2024-12-08 |
| Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients (NCT06706674) | Intra-Cellular Therapies, Inc. | 2024-12-06 |
| Geriatric Oncology Care in Brazil: Remote Geriatric Assessment-Driven Interventions With Supportive Care (NCT07084454) | Cristiane Decat Bergerot, PhD | 2024-12-06 |
| A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 in Participants With Dyslipidaemia (NCT06834932) | AstraZeneca | 2024-12-06 |
| A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients (NCT06497985) | Chipscreen Biosciences, Ltd. | 2024-12-06 |
| The MANTRA Trial (MANdibular TRauma and Antibiotic Use) (NCT05964140) | East Lancashire Hospitals NHS Trust | 2024-12-06 |
| Standard Versus High Dose ED-Initiated Buprenorphine Induction (NCT06494904) | Yale University | 2024-12-06 |
| CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial (NCT06027099) | Stanford University | 2024-12-05 |
| Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction (NCT06362395) | University Health Network, Toronto | 2024-12-05 |
| A Long-term Safety and Efficacy Study of N-Acetyl-GED-0507-34-LEVO Gel 5%, in Subjects With Acne Vulgaris (GEDACNE-LT) (NCT07389109) | PPM Services S.A. | 2024-12-05 |
| Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (NCT06382948) | MedSIR | 2024-12-05 |
| A Phase III Clinical Trial for Efficacy and Safety Evaluation of JP-1366 Tablets on Reflux Esophagitis (NCT06850480) | Livzon Pharmaceutical Group Inc. | 2024-12-05 |
| Nipocalimab in Moderate to Severe Sjogren's Disease (NCT06741969) | Janssen Research & Development, LLC | 2024-12-04 |
| Clinical Trial to Evaluate the Safety and Efficacy of NTCB02-1 in Patients Who Require Parenteral Nutrition (NCT06625957) | Yuhan Corporation | 2024-12-04 |
| Study to Evaluate the Non-inferiority of Low-dose HIPEC Versus High-dose HIPEC in the Treatment of PMP (HIPEC-PMP) (NCT06513065) | University of Southampton | 2024-12-04 |
| A Study to Evaluate the Efficacy and Safety of Daridorexant in Participants With Insomnia Disorder (NCT07028697) | Nxera Pharma Korea Co., Ltd. | 2024-12-04 |
| Phase 3 Efficacy and Safety Study of GTX-102 in Pediatric Subjects With Angelman Syndrome (AS) (NCT06617429) | Ultragenyx Pharmaceutical Inc | 2024-12-03 |
| Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation (NCT06465953) | Institut de Recherches Internationales Servier | 2024-12-03 |
| A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA) (NCT06706622) | H. Lundbeck A/S | 2024-12-03 |
| A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) (NCT06685757) | Biogen | 2024-12-03 |
| Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor (NCT06472245) | OSE Immunotherapeutics | 2024-12-03 |
| A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy (NCT06679946) | Alnylam Pharmaceuticals | 2024-12-03 |
| Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy (NCT06721520) | The Cleveland Clinic | 2024-12-03 |
| A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab (NCT06706817) | AstraZeneca | 2024-12-03 |
| Evaluate the Efficacy and Safety of Co-administration of JW0104+C2402 in Patients With Hypertension and Dyslipidemia (NCT06643130) | JW Pharmaceutical | 2024-12-02 |
| A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1 (NCT06694805) | ViiV Healthcare | 2024-12-02 |
| A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023) (NCT06667700) | Merck Sharp & Dohme LLC | 2024-12-02 |
| A Study of BGM0504 in Poorly Controlled Type 2 Diabetes Patients Only Through Diet and Exercise (NCT06716203) | BrightGene Bio-Medical Technology Co., Ltd. | 2024-12-02 |
| Apixaban Prophylaxis for Prevention of Left Ventricular Thrombus Following Anterior Myocardial Infarction (NCT06742567) | National Institute of Cardiovascular Diseases, Pakistan | 2024-12-02 |
| Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNE (NCT07199894) | Mansoura University | 2024-12-01 |
| Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation (NCT06801522) | Shaheed Mohtarma Benazir Bhutto Institue of Trauma | 2024-12-01 |