| Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation Surgery (NCT06680245) | St. Joseph's Healthcare Hamilton | 2024-12-01 |
| Evaluate the Efficacy and Safety of KK8398 in Patients With Achondroplasia（AOBA Study） (NCT06926491) | Kyowa Kirin Co., Ltd. | 2024-12-01 |
| Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Patients With Early Breast Cancer (NCT06407401) | European Organisation for Research and Treatment of Cancer - EORTC | 2024-12-01 |
| Venoactive Drug Treatment of Pelvic Venous Disorders (NCT06584799) | Pirogov Russian National Research Medical University | 2024-12-01 |
| A Prospective, Multicenter, Blind, Randomized Controlled, Optimal Clinical Trial to Evaluate the Safety and Efficacy of Medical Collagen Fillers for Facial Dermal Tissue Filling to Correct Frontal Wrinkles (crow's Feet) (NCT06703294) | Fiman (Changchun) Pharmaceutical Biotechnology Company Limited | 2024-12-01 |
| An Open Label Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacologic Properties of High Dose Ambroxol Hydrochloride in Adult (≥ 18 Years of Age) Subjects With MPS III (NCT06614894) | Ozlem Goker-Alpan | 2024-12-01 |
| Effect of Intravaginal Prasterone on Symptoms of Genitourinary Syndrome of Menopause (GSM) in Women in Menopause With Previous Breast Cancer (NCT06611514) | European Institute of Oncology | 2024-12-01 |
| RCT to Test Regional Anesthesia Effect on Decreased Opiate Use (NCT06989866) | United States Naval Medical Center, Portsmouth | 2024-12-01 |
| Using ctDNA to Guide Treatment Decisions for Stage III Gastric Cancer (NCT06939439) | The First Affiliated Hospital with Nanjing Medical University | 2024-12-01 |
| Intralesional Treatment of Keloids (NCT06729840) | Sohag University | 2024-12-01 |
| Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle (NCT06676475) | Misr University for Science and Technology | 2024-12-01 |
| BuCy Vs. TBICy for Allo-HSCT in T-ALL Patients (NCT06673459) | The First Affiliated Hospital of Soochow University | 2024-12-01 |
| Adebrelimab Combined with Chemotherapy and Thoracic Radiotherapy for First-line Treatment of ES-SCLC (NCT06672133) | Jinming Yu | 2024-12-01 |
| Cellular Immunotherapy in Recipients of Human Leukocyte Antigen (HLA)-Mismatched, Living Donor Kidney Transplants (NCT03605654) | Medeor Therapeutics, Inc. | 2024-12-01 |
| Study of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist（Diphenhydramine）in Advanced and Metastatic Non-Small Cell Lung Cancer (NCT06704620) | Tianjin Medical University Cancer Institute and Hospital | 2024-12-01 |
| Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock (NCT06696391) | Western University, Canada | 2024-12-01 |
| Study of Ondansetron in the Prevention of Sleep Syncope: The Nineth Prevention of Syncope Trial (POST9) (NCT05657925) | University of Calgary | 2024-12-01 |
| A Study of HB-202/HB-201 With Pembrolizumab in Patients With HPV16+ Recurrent/Metastatic Oropharyngeal Cancer (NCT06513884) | Hookipa Biotech GmbH | 2024-12-01 |
| Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery (NCT06802354) | Jelena Krunic | 2024-12-01 |
| Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer (NCT04516681) | Fudan University | 2024-12-01 |
| Effect of Olive Leaf Extracts on Endothelial Dysfunction in Patients With Acute Coronary Syndrome (NCT06723002) | University of Monastir | 2024-12-01 |
| Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery (NCT06665438) | Al-Azhar University | 2024-12-01 |
| Immunoscore As Decision Guidance for Adjuvant Chemotherapy in Colon Cancer (NCT04488159) | Johannes Laengle, MD, PhD | 2024-12-01 |
| Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma (NCT02546102) | Precision Life Sciences Group | 2024-12-01 |
| Maintenance Therapy After Platinum-containing Chemotherapy in Patients With Recurrent Ovarian Cancer (NCT06188455) | The First Affiliated Hospital of Xiamen University | 2024-12-01 |
| Safety and Efficacy of Conestat Alfa for ACE-Induced Angioedema (NCT06679426) | University of Cincinnati | 2024-12-01 |
| Study to Assess the Efficacy and Safety of GP681 Versus Placebo for Postexposure Prophylaxis Against Influenza (NCT06574503) | Jiangxi Qingfeng Pharmaceutical Co. Ltd. | 2024-12-01 |
| Alleviating Carbohydrate Counting for Patients with Type-1 Diabetes Using a Closed Loop System with Weekly Subcutaneous Semaglutide (NCT06387199) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2024-12-01 |
| Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE (NCT06669754) | Pharvaris Netherlands B.V. | 2024-12-01 |
| Effect of Fenugreek Fibre on Gut Microbiome (NCT06006416) | RDC Clinical Pty Ltd | 2024-12-01 |
| A Randomized Controlled Trial on the Efficacy and Safety of Butylphthalide in Reducing Myocardial Infarction Size and Improving Outcomes in STEMI Patients After Primary PCI (NCT06704685) | Xiangya Hospital of Central South University | 2024-12-01 |
| Neoadjuvant Immunotherapy Plus Chemotherapy Followed by Concurrent Chemoradiotherapy and Consolidative Immunotherapy for Locally Advanced Non-small Cell Lung Cancer (NCT06734702) | Sun Yat-sen University | 2024-11-30 |
| Blinatumomab in Refractory Myasthenia Gravis (BLINA-MG) (NCT06684184) | Zhongming Qiu | 2024-11-30 |
| Different Doses of Sirolimus for the Treatment of Cystic Lymphatic Malformations (NCT06673290) | West China Hospital | 2024-11-30 |
| Using Three Different Doses of Hyperbaric Prilocaine 2% Local Anaesthetic ( 40,50 and 60mg ),Through Spinal Anaesthesia in Knee Arthroscopy Patients to Compare Time to Void (NCT06703580) | Cairo University | 2024-11-30 |
| Long-term Safety and Tolerability of MY008211A Tablets in Patients With Paroxysmal Nocturnal Hemoglobinuria (NCT06933914) | Wuhan Createrna Science and Technology Co., Ltd | 2024-11-30 |
| Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery (NCT06660823) | Ain Shams University | 2024-11-30 |
| Single-arm Clinical Trial of TACE in Combination With Icaritin as Adjuvant Therapy After Surgery in Patients With Hepatocellular Carcinoma at High Risk of Recurrence (NCT06644937) | Zhujiang Hospital | 2024-11-29 |
| A Study of SHR-A2009 Versus Platinum-based Chemotherapy in EGFR-mutated, Advanced or Metastatic NSCLC (NCT06671379) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2024-11-29 |
| Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease) (NCT05532813) | Assistance Publique - Hôpitaux de Paris | 2024-11-29 |
| The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal Cholangiocarcinoma (NCT06355427) | Mara Veenstra, MD | 2024-11-29 |
| Efficacy and Safety of Early Combined Therapy With PCSK9 Inhibitors and Statins in Acute Ischemic Stroke (NCT06696820) | Xiang Luo | 2024-11-29 |
| Topical Ruxolitinib for Face and Neck Vitiligo of Adult Chinese Patients Refractory to Topical Tacrolimus (NCT06719024) | Hospital Authority, Hong Kong | 2024-11-29 |
| A Study of BGM0504 in Participants with Type 2 Diabetes (NCT06716216) | BrightGene Bio-Medical Technology Co., Ltd. | 2024-11-29 |
| A Sudy to Evaluate the Efficacy and Safety of TNM001 in High-risk Infants (NCT06710925) | Zhuhai Trinomab Pharmaceutical Co., Ltd. | 2024-11-28 |
| Anterior Temporal Lobectomy in Temporal Glioblastoma (NCT07021339) | University Hospital, Bonn | 2024-11-28 |
| Induced Hypertension in Acute PRogrESsive Perforating Artery Stroke Using Peripheral Dilute noREpinephrine (NCT06059144) | University Hospital, Bordeaux | 2024-11-28 |
| A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 1) (NCT06687967) | Sanofi | 2024-11-28 |
| A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China (NCT06666855) | Santen Pharmaceutical Co., Ltd. | 2024-11-28 |
| Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer (NCT06459687) | Lee's Pharmaceutical Limited | 2024-11-28 |
| A Phase III Study Comparing Taletrectinib With Standard Therapy in ROS1 Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients (NCT06564324) | Nuvation Bio Inc. | 2024-11-27 |
| Nab-TPC vs GP Combined With Camrelizumab in the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma (NCT06669611) | Sun Yat-sen University | 2024-11-27 |
| A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients (NCT06712771) | Visirna Therapeutics HK Limited | 2024-11-27 |
| A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56 (NCT06683742) | EyePoint Pharmaceuticals, Inc. | 2024-11-27 |
| A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC (NCT06627647) | AstraZeneca | 2024-11-27 |
| Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body (NCT06470243) | SWOG Cancer Research Network | 2024-11-27 |
| Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration (NCT06495918) | Ocular Therapeutix, Inc. | 2024-11-27 |
| A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer (NCT06670196) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2024-11-27 |
| Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BDLL Chinese Cohort (NCT06649721) | Huashan Hospital | 2024-11-27 |
| ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty (NCT06611319) | Prof. Stavros Konstantinides, MD | 2024-11-26 |
| A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age (NCT06693895) | GlaxoSmithKline | 2024-11-26 |
| A Study on the Immunogenicity and Safety of 3 Different Dose Concentrations of a Respiratory Syncytial Virus Vaccine in Infants and Toddlers (NCT06705140) | Sanofi Pasteur, a Sanofi Company | 2024-11-25 |
| Anlotinib Plus Nab-Paclitaxels and S-1 for Patients with Advanced Biliary Tract Cancer As Second-Line Treatment (NCT06662877) | Sun Yat-sen University | 2024-11-25 |
| Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06) (NCT06635824) | Genmab | 2024-11-25 |
| HEALSea Nasal Spray for Prevention of Infections in Children (NCT06582589) | Lallemand Pharma AG | 2024-11-25 |
| A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2) (NCT06687980) | Sanofi | 2024-11-25 |
| Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011) (NCT06651281) | Merck Sharp & Dohme LLC | 2024-11-25 |
| Use of a Freeze-dried Amniotic Membrane Post Crosslinking in Subjects With Progressive Keratoconus (NCT06450470) | TBF Genie Tissulaire | 2024-11-25 |
| Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With Sacubitril/Allisartan (NCT07704697) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2024-11-23 |
| A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation (NCT06647498) | Washington University School of Medicine | 2024-11-22 |
| Vitamin C Plus Cordyceps to Quality of Life in Patients With Terminal Stage Pancreatic Cancer (NCT06598033) | Fudan University | 2024-11-22 |
| SHR-A1904 Compared With Investigator's Choice of Therapy in Claudin18.2 Positive Patitens With Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (NCT06649292) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2024-11-22 |
| A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation (NCT05552157) | Washington University School of Medicine | 2024-11-22 |
| A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer (NCT06532006) | Shanghai Henlius Biotech | 2024-11-22 |
| A Study to Evaluate the Efficacy and Safety of HCP1004 in Chronic Low-Back Pain Patients (NCT06595004) | Hanmi Pharmaceutical Company Limited | 2024-11-22 |
| Vitamin C Plus Cordyceps to Chemotherapy Related Anemia in Pancreatic Cancer (NCT06601283) | Fudan University | 2024-11-22 |
| A Phase 3 Study of NTLA-2001 in ATTRv-PN (NCT06672237) | Intellia Therapeutics | 2024-11-22 |
| EMPA-ESUS. a Randomised Control Trial to Investigate the Impact of Empagliflozin on Left Atrial Function in Patients with Embolic Stroke of Undetermined Source (NCT06715449) | University of East Anglia | 2024-11-22 |
| A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps (NCT06639295) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2024-11-22 |
| Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients (NCT06690398) | Intra-Cellular Therapies, Inc. | 2024-11-22 |
| An Open-Label Study to Assess the Long-term Safety of AXS-05 in Subjects With Dementia of the Alzheimer's Type, ADVANCE-2 and ACCORD-2 Extension Study (NCT06736509) | Axsome Therapeutics, Inc. | 2024-11-21 |
| Short Versus Long Antiplatelet Therapy After TAVI (NCT06518317) | University Hospital, Caen | 2024-11-21 |
| Efficacy and Safety of Roflumilast Cream in Subjects With Atopic Dermatitis (NCT06631170) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2024-11-21 |
| Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older (NCT06460506) | Vertex Pharmaceuticals Incorporated | 2024-11-21 |
| A Clinical Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) to Treat Newly-diagnosed Metastatic Non-small Cell Lung Cancer (MK-3475A-F84) (NCT06698042) | Merck Sharp & Dohme LLC | 2024-11-21 |
| A Multi-centered，Randomized，Double-blind，Placebo-controlled Study to Evaluate the Efficacy and Safety of SHR-1703 in Eosinophilic Asthma (NCT06653322) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2024-11-21 |
| A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus (NCT06617325) | UCB Biopharma SRL | 2024-11-21 |
| A Study of Surgical Techniques During Cystectomy (NCT06703476) | Memorial Sloan Kettering Cancer Center | 2024-11-21 |
| Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic Therapy (NCT06857773) | The Netherlands Cancer Institute | 2024-11-21 |
| Norepinephrine and Vasopressin for Rescue Versus Early Vasopressin for Vasopressor Dependent Sepsis (NCT06464510) | Hospital do Coracao | 2024-11-21 |
| Evaluation of Rovadicitinib Compared to the Protocol Selected by Researchers in Third Line and Subsequent Studies of Moderate to Severe Chronic Graft-versus-host Disease (NCT06682169) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-11-20 |
| Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke (NCT06587347) | Capital Medical University | 2024-11-20 |
| SGLT2 Adjunct in T1D (NCT07591077) | Ain Shams University | 2024-11-20 |
| Personalized Evaluation of Susptected Myocardial Ischemia (NCT06708000) | Gødstrup Hospital | 2024-11-20 |
| Vafseo Outcomes In-Center Experience (NCT06520826) | USRC Kidney Research | 2024-11-20 |
| Analysis of 18F-XTR006 PET Imaging in Cognitively Normal Subjects, and Patients With MCI and AD (NCT07115238) | Sinotau Pharmaceutical Group | 2024-11-20 |
| Study of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1 (NCT06532656) | Gilead Sciences | 2024-11-20 |
| A Study to Assess Efficacy and Safety of N-Acetyl-GED-0507-34-LEVO Gel 5%, in Patients With Acne Vulgaris (GEDACNE-1) (NCT07384195) | PPM Services S.A. | 2024-11-19 |
| Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML (NCT06578247) | Daiichi Sankyo | 2024-11-19 |
| Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery (NCT06361238) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2024-11-19 |