| Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic Patients (NCT07073768) | Khyber Medical College, Peshawar | 2025-07-01 |
| Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents (NCT07168980) | Children's Cancer Group, China | 2025-07-01 |
| Efficacy of Semaglutide in Improving Neurological Outcomes After Endovascular Thrombectomy for Acute Ischemic Stroke: A Randomized Double-Blind Controlled Trial (NCT07030621) | RenJi Hospital | 2025-07-01 |
| Comparative Study of Two Recombinant Human Erythropoietin Products in Chronic Kidney Disease Patients (NCT06352138) | Megalabs | 2025-07-01 |
| Metformin Alleviates Abnormal Glucose Metabolism Induced by Statins in Schizophrenia Patients (NCT07045142) | Central South University | 2025-07-01 |
| Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome (NCT06953466) | Quoin Pharmaceuticals | 2025-07-01 |
| Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease (NCT06297096) | National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland | 2025-07-01 |
| Olanzapine for Prevention of Vomiting in Children and Adolescents Receiving Highly Emetogenic Chemotherapy (NCT07035821) | Shanghai Children's Medical Center | 2025-07-01 |
| PD-1 (Programmed Death-1) Versus PD-L1 (Programmed Death-ligand 1) Immune Check Point Inhibitors Combined With Chemotherapy, With or Without Bevacizumab, In Patients With Metastatic, Persistent Or Recurrent Cervical Cancer (NCT07472153) | N.N. Alexandrov National Cancer Centre | 2025-07-01 |
| A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration (NCT06470373) | Rophibio, Inc. | 2025-07-01 |
| Comparing Endocrine Therapy Combined With High-Dose Palbociclib and Hydroxychloroquine to Endocrine Therapy Combined With Standard-Dose Palbociclib for Hormone Receptor-Positive and HER2-Negative Advanced Breast Cancer (NCT07061717) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2025-07-01 |
| A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED) (NCT07155668) | Viridian Therapeutics, Inc. | 2025-07-01 |
| Effect of Amitriptyline and Trifluoperazine on Patients With Functional Dyspepsia (NCT07008235) | Md. Moktadirul Hoque Shuvo | 2025-07-01 |
| Efficacy, Safety, and Pharmacokinetics of FP-014, 11.25 mg in Patients With Advanced Prostate Cancer (NCT06795178) | Foresee Pharmaceuticals Co., Ltd. | 2025-07-01 |
| Transfusion Reduction in High-Bleeding-Risk Cardiac Surgery With Desmopressin (NCT07012837) | Imam Abdulrahman Bin Faisal University | 2025-07-01 |
| Evaluation of The Periodontal Parameters Following Non-Surgical Periodontal Therapy With and Without Adjunctive Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial (NCT07090265) | Cairo University | 2025-07-01 |
| NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer (NCT07309289) | Shanghai Zhongshan Hospital | 2025-07-01 |
| Clinical Trial for the Evaluation of Safety and Efficacy of Drop 0.4% (NCT06985875) | Avizor SA | 2025-07-01 |
| Confirmatory Study 3 of KPS-0373 in Patients With Spinocerebellar Degeneration (NCT07040137) | Kissei Pharmaceutical Co., Ltd. | 2025-07-01 |
| Bioavailability and Bioequivalence Study of ER Torsemide and Spironolactone FDC Tablet in Healthy Subjects (NCT07015671) | Sarfez Pharmaceuticals, Inc. | 2025-07-01 |
| ACB vs no Block for Pediatric ACL Reconstruction (NCT06875427) | Isabella Jaramillo | 2025-07-01 |
| Hypofractionated Versus Conventional Chemoradiotherapy Followed by Consolidative Immunotherapy in Locally Advanced NSCLC (NCT07052669) | Sun Yat-sen University | 2025-07-01 |
| Treatment of Periodontitis by Tulsi Gel (NCT06675578) | Al-Azhar University | 2025-07-01 |
| A Phase II/III of Hepenofovir Fumarate Tablets (HTS) for Chronic Hepatitis B (NCT07203118) | Xi'an Xintong Pharmaceutical Research Co.,Ltd. | 2025-07-01 |
| Evaluate the Efficacy and Safety of Probiotic 6600 as an Adjuvant Therapy for Colitis (NCT07047339) | Changhai Hospital | 2025-07-01 |
| Study of Fecal Microbiota Transplantation (FMT) in Severe IBS Patients (NCT06433180) | Assistance Publique - Hôpitaux de Paris | 2025-07-01 |
| Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC (NCT06855277) | Novartis Pharmaceuticals | 2025-07-01 |
| A Randomized Study of a Short Duration Therapy for Candidemia (NCT06859671) | Assistance Publique - Hôpitaux de Paris | 2025-07-01 |
| Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair (NCT05505747) | Austin V Stone | 2025-07-01 |
| A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis (NCT07054515) | Azafaros B.V. | 2025-06-30 |
| FSRT Combines With Bevacizumab for Multiple Brain Metastases in Lung Adenocarcinoma (NCT07058428) | Sun Yat-Sen University Cancer Center | 2025-06-30 |
| Total Neoadjuvant 6 Cycles of Chemotherapy Versus 3 Cycles in Partial Responder Patients Diagnosed With Epithelial Ovarian Cancer (NCT06980545) | Assiut University | 2025-06-30 |
| Use of PRP in Open Surgery for Type A Aortic Dissection (NCT07005661) | Beijing Anzhen Hospital | 2025-06-30 |
| FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration (NCT07004075) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2025-06-30 |
| A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032) (NCT06966700) | Merck Sharp & Dohme LLC | 2025-06-30 |
| A Study of SRP-9005 in Limb Girdle Muscular Dystrophy Type 2C/R5 Pediatric and Adult Participants (NCT06952686) | Sarepta Therapeutics, Inc. | 2025-06-30 |
| A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis (NCT07082543) | Azafaros B.V. | 2025-06-30 |
| A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC) (NCT07082725) | Azafaros B.V. | 2025-06-30 |
| A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (NCT07023341) | Bayer | 2025-06-30 |
| Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY) (NCT06973629) | Brainstorm-Cell Therapeutics | 2025-06-30 |
| A Comparative Study to Valuating the Efficacy and Safety of QL1206 and Prolia® (NCT07062978) | Qilu Pharmaceutical Co., Ltd. | 2025-06-27 |
| Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study (NCT07001800) | Kardigan, Inc. | 2025-06-27 |
| A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease (NCT06998524) | Hoffmann-La Roche | 2025-06-27 |
| Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI (NCT06501482) | Assistance Publique - Hôpitaux de Paris | 2025-06-27 |
| A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Moderate to Severe Hidradenitis Suppurativa (NCT07007637) | MoonLake Immunotherapeutics AG | 2025-06-27 |
| E-Mindfulness Approaches for Living After Breast Cancer (NCT06748222) | NRG Oncology | 2025-06-27 |
| Prospective Single-Arm Clinical Trial of GO Regimen for HLH. (NCT07339345) | Beijing Friendship Hospital | 2025-06-27 |
| The Efficacy and Safety of Reconyl in Acute Cough Treatment (NCT07420491) | Dexa Medica Group | 2025-06-26 |
| A Study of Teduglutide in Chinese Adults With Short Bowel Syndrome (NCT06973304) | Takeda | 2025-06-26 |
| Global Open-Label Extension Study of Del-desiran for the Treatment of DM1 (NCT07008469) | Avidity Biosciences, Inc. | 2025-06-26 |
| Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study (NCT06937086) | Eli Lilly and Company | 2025-06-26 |
| Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight (NCT06937099) | Eli Lilly and Company | 2025-06-26 |
| A Study to Evaluate the Immunogenicity and Safety of an EV71 Vaccine (Envacgen®) in Children Aged 6 to <10 Years Compared to Children Aged 2 to <6 Years (NCT07178522) | Medigen Vaccine Biologics Corp. | 2025-06-25 |
| A Long-term Trial of EB-1020 in Adult Patients With ADHD (NCT06926829) | Otsuka Pharmaceutical Co., Ltd. | 2025-06-25 |
| REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults (NCT07015905) | Regeneron Pharmaceuticals | 2025-06-25 |
| Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (NCT07037459) | Amgen | 2025-06-25 |
| Noradrenaline Versus Standard Blood Pressure Management for Perioperative Hypotension in Non-cardiac Surgery (NCT06885268) | Jagiellonian University | 2025-06-25 |
| Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine (NCT07050277) | University of Toronto | 2025-06-24 |
| Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers) (NCT07003919) | DBV Technologies | 2025-06-24 |
| Randomized Controlled Multicenter Study Comparing Steroid Therapy Plus Anticoagulants to Steroid Therapy Alone in Deep Venous Thrombosis of Behçet's Syndrome (NCT06780462) | Assistance Publique - Hôpitaux de Paris | 2025-06-24 |
| Efficacy of Nab-PHP Versus TCbHP in Neoadjuvant Therapy for HER2-positive Early Breast Cancer (NCT07057427) | Henan Cancer Hospital | 2025-06-24 |
| VK2735 for Weight Management Phase 3 (NCT07104500) | Viking Therapeutics, Inc. | 2025-06-23 |
| Study on the Short-term Efficacy and Safety of Recombinant Human Thrombopoietin Combined With Immunosuppressant Sequential Eltrombopag Ethanolamine Dry Suspension in the Treatment of SAA/TD-NSAA (NCT07001397) | Peking Union Medical College Hospital | 2025-06-23 |
| Ketorolac at Lower Doses for Analgesic Pain Control in ICU: A Pilot Feasibility Study (NCT06819956) | University of Alberta | 2025-06-23 |
| VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2) (NCT07104383) | Viking Therapeutics, Inc. | 2025-06-23 |
| Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis. (NCT06846281) | Novartis Pharmaceuticals | 2025-06-23 |
| A Study to Evaluate the Efficacy and Safety of LZM012 ( Psoriasis ) (NCT07746479) | Livzon Pharmaceutical Group Inc. | 2025-06-23 |
| Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2) (NCT06961214) | GlaxoSmithKline | 2025-06-23 |
| Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1) (NCT06959225) | Incyte Corporation | 2025-06-23 |
| A Clinical Study of TQB2102 Versus Docetaxel Plus Trastuzumab and Pertuzumab in the Treatment of HER2 Positive Recurrent or Metastatic Breast Cancer (NCT07003074) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2025-06-23 |
| Phase 3 Maternal Safety & Immunogenicity Trial of MVA-BN® in DRC (NCT06844500) | Jean-Pierre Van geertruyden | 2025-06-23 |
| Bioequivalence ANDA SNP Clinical Study - Raloxifene and Single Nucleotide Polymorphisms (NCT06062810) | Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair | 2025-06-21 |
| A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa (NCT07016750) | Krystal Biotech, Inc. | 2025-06-20 |
| Buprenorphine for Individuals in Jail (NCT06306443) | Friends Research Institute, Inc. | 2025-06-20 |
| Efficacy and Safety of Sodium Hyaluronate Gel Combined With Sodium Bicarbonate Versus Sodium Bicarbonate Alone in Prevention of Failed Back Surgery Syndrome (NCT06999993) | Misr University for Science and Technology | 2025-06-20 |
| A Study of Prusogliptin Tablets Combined With Dapagliflozin Tablets and Metformin Hydrochloride Extended Release Tablets in Type 2 Diabetes (NCT07026968) | CSPC Ouyi Pharmaceutical Co., Ltd. | 2025-06-20 |
| An Open Prospective Randomized Clinical Study of the Effectiveness, Tolerability and Safety of a Single Intraperitoneal Use of the Drug "Prospidelong, Powder for the Preparation of a Gel for Topical Use, 1000 mg in Vials, Package No. 1" in Patients With Disseminated Gastric Cancer, Phase I-II (NCT06232434) | Research Institute for Physical Chemical Problems of the Belarusian State University | 2025-06-20 |
| SSGJ-707 in Advanced Non-Small Cell Lung Cancer (NCT06980272) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2025-06-20 |
| Wide-Awake Local Anesthesia No Tourniquet (WALANT) With Versus Without Hyaluronidase for Hand Surgery (NCT07000058) | Misr University for Science and Technology | 2025-06-20 |
| Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1) (NCT06959095) | GlaxoSmithKline | 2025-06-20 |
| A Clinical Study Evaluating the Diagnostic Performance and Safety of PET for the Deposition of Aβ Plaques in the Brain of Participants With Normal Cognitive Function, MCI and AD Using [18F]Fluorbetazine Injection (NCT07764679) | HTA Co., Ltd. | 2025-06-20 |
| Long-Term Extension Study of Vosoritide to Treat Children With Hypochondroplasia (NCT07073014) | BioMarin Pharmaceutical | 2025-06-20 |
| A Trial on the Treatment of Bronchial Asthma With Budesonide Formoterol Combined With Immune Modulators (Staphylococcus and Neisseria Tablets) (NCT06895460) | The First Affiliated Hospital with Nanjing Medical University | 2025-06-20 |
| Early Aggressive Strategy for Treatment of Lipid-Lowering in Acute Ischemic Stroke Delivered With Endovascular Therapy for Large Artery Occlusion (NCT07002476) | Shanghai East Hospital | 2025-06-19 |
| Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases (NCT06888817) | The Netherlands Cancer Institute | 2025-06-19 |
| A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia Areata (NCT07023302) | AbbVie | 2025-06-19 |
| A PAN-USR TB Multi-Center Trial (NCT06905522) | Shenzhen Third People's Hospital | 2025-06-18 |
| STI Testing to Enhance PrEP Use in Pregnancy (NCT06919614) | Botswana Harvard AIDS Institute Partnership | 2025-06-18 |
| A Study to Evaluate the Efficacy and Safety of Orally Administered Extract of Orthosiphon Stamineus (NuvastaticTM-C5OSEW5050ESA) in Patient With Breast Cancer Undergoing Chemotherapy (NCT07669506) | Natureceuticals Sdn Bhd | 2025-06-17 |
| A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis (NCT06832618) | Incyte Corporation | 2025-06-17 |
| Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial (NCT06263816) | University Hospital, Tours | 2025-06-17 |
| A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab (NCT06880744) | AbbVie | 2025-06-17 |
| A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE) (NCT07037771) | Arrowhead Pharmaceuticals | 2025-06-17 |
| A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease (NCT06944522) | BlueRock Therapeutics | 2025-06-17 |
| A Study to Assess the Safety and Efficacy of Oral LPCN 1154A in Women With Severe PPD (NCT06979544) | Lipocine Inc. | 2025-06-16 |
| Feasibility of Enhanced Recovery After Surgery Without Prophylactic Abdominal Drainage Tubes After Laparoscopic Distal Gastrectomy For Gastric Cancer (NCT07029269) | Zuoyi Jiao | 2025-06-16 |
| A Study of 2 Doses of Tetravalent Dengue Vaccine (TDV) in Infants and Toddlers (NCT06665035) | Takeda | 2025-06-16 |
| Comparing UTD2 Combined With Capecitabine to Capecitabine as Adjuvant Therapy for Non-pCR TNBC Patients (NCT07021261) | Fudan University | 2025-06-16 |
| Corticosteroids Before Extubation in Pediatric Intensive Care Unit (NCT06722118) | Assistance Publique - Hôpitaux de Paris | 2025-06-15 |
| Clinical Study of CS-001 As a Treatment for Canities (Grey Hair) (NCT06745336) | Applied Biology, Inc. | 2025-06-15 |