| Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit Constipation (NCT07277907) | Third Military Medical University | 2025-11-13 |
| Rivaroxaban vs Warfarin in Patients With Mechanical Heart Valves (NCT07456085) | Rawalpindi Institute of Cardiology | 2025-11-13 |
| Improving Neuroprotective Strategy for Ischemic Stroke Before Endovascular Thrombectomy by Intravenous Tirofiban (NCT07135089) | General Hospital of Shenyang Military Region | 2025-11-13 |
| Comparing High and Low Dose Iron Treatments for People on Peritoneal Dialysis: The PALaDIN Study (NCT06884280) | Hull University Teaching Hospitals NHS Trust | 2025-11-13 |
| NO Re-excision MelanomA - NORMA 2 (NCT07530887) | Marieke Goodijk | 2025-11-13 |
| A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Children (6 to < 12 Years Old) With Nonsegmental Vitiligo (NCT06804811) | Incyte Corporation | 2025-11-13 |
| A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome (NCT07281079) | Neuren Pharmaceuticals Limited | 2025-11-12 |
| A Randomised, Open-label, Multicentre Phase III Clinical Study to Evaluate the Efficacy and Safety of JS105 Combined With Dalpiciclib and Fulvestrant Compared With Dalpiciclib and Fulvestrant in Patients With PIK3CA-mutated, HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer. (NCT07207070) | Risen (Suzhou) Pharma Tech Co., Ltd. | 2025-11-12 |
| A Phase Ib/III Study of Suvemcitug Plus FTD/TPI in Participants With Refractory Metastatic Colorectal Cancer (NCT07361003) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2025-11-12 |
| A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (NCT07170150) | Hoffmann-La Roche | 2025-11-12 |
| Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC (NCT06998758) | Sixth Affiliated Hospital, Sun Yat-sen University | 2025-11-11 |
| AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL (NCT07215585) | AstraZeneca | 2025-11-11 |
| A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis (NCT07225504) | Novartis Pharmaceuticals | 2025-11-11 |
| Study of Stapokibart Injection in Subjects With Moderate to Severe Bullous Pemphigoid (NCT07210554) | Chengdu Kangnuoxing Biopharma,Inc. | 2025-11-11 |
| A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037) (NCT07216482) | Merck Sharp & Dohme LLC | 2025-11-11 |
| Safe Effective Therapy With Low-Dose Glucocorticoid in ANCA-Associated Vasculitis (SAFE-LOW) (NCT06983821) | Ottawa Hospital Research Institute | 2025-11-10 |
| Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body (NCT06820957) | Children's Oncology Group | 2025-11-10 |
| Adjunctive Rifampin for the Treatment of Prosthetic Valve Endocarditis Due to S. Aureus (NCT07253688) | Todd C. Lee MD MPH FIDSA | 2025-11-10 |
| BDB-001 Phase III Trial in ANCA-Associated Vasculitis (NCT07168161) | Staidson (Beijing) Biopharmaceuticals Co., Ltd | 2025-11-10 |
| Vinpocetine in Patients With Parkinsonian Disease (NCT07229664) | Tanta University | 2025-11-10 |
| Validation of the Sentinel Lymph Node Technique in Early-stage Ovarian Cancer (SENTOV II) (NCT06963268) | Instituto de Investigacion Sanitaria La Fe | 2025-11-10 |
| Sodium Bicarbonate in Intra-dialytic Hypertension in Chronic Hemodialysis Patients (NCT07231900) | Assaf-Harofeh Medical Center | 2025-11-10 |
| A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis (NCT07112378) | Regeneron Pharmaceuticals | 2025-11-10 |
| A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010) (NCT07071623) | Merck Sharp & Dohme LLC | 2025-11-10 |
| Metformin in Parkinson Disease (NCT07229651) | Tanta University | 2025-11-10 |
| A Randomized Controlled Trial Evaluating the Feasibility and Preliminary Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Advanced Epithelial Ovarian Cancer (NCT07544030) | tongweihua | 2025-11-10 |
| Comparison of Efficacy and Safety Profile Between Moisturizers Containing a Combination of 5% Hydro-Urea, Ceramide, With MultiVesicular Emulsion Technology and Petrolatum on Dry Skin in the Elderly (NCT07739355) | Dr. dr. Lili Legiawati, SpKK(K) | 2025-11-10 |
| Bempedoic Acid Versus Statins in Primary-Prevention Patients With Suboptimal Statin Adherence: Effects on LDL-C Reduction and Tolerability (NCT07239414) | Sohaib Ashraf | 2025-11-10 |
| Efficacy and Safety of ZSP1273 in Children 12-17 Years Old With Influenza A (NCT07229820) | Guangdong Raynovent Biotech Co., Ltd | 2025-11-08 |
| A Study on a New Tetravalent Dengue Vaccine (TDV) Formulation in Healthy Adults (NCT07047521) | Takeda | 2025-11-07 |
| Effect of Early Dexamethasone on Major Complications and All-cause Mortality in Severe Burns (NCT06968559) | Nantes University Hospital | 2025-11-07 |
| Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain (NCT07226258) | Saol Therapeutics Inc | 2025-11-07 |
| Phase III Clinical Study Evaluating the Safety, Pharmacokinetics, and Efficacy of JKN2301 Dry Suspension in Pediatric Patients Aged 2 to Under 12 Years With Influenza (NCT07357051) | Joincare Pharmaceutical Group Industry Co., Ltd | 2025-11-07 |
| A Study Comparing QLS32015 Monotherapy Versus Pomalidomide, Dexamethasone (Pd) or Selinexor, Dexamethasone (Sd) in Participants With Relapsed or Refractory Multiple Myeloma (NCT07138209) | Qilu Pharmaceutical Co., Ltd. | 2025-11-07 |
| A Study to Evaluate the Efficacy and Safety of 608 in Adult Subjects With Active Ankylosing Spondylitis(AS) (NCT07261644) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2025-11-07 |
| Prophylactic Anti-aRrhythmic Therapy With Amiodarone in Critically Ill Patients Admitted for an Out-of-hospital Cardiac Arrest With Initial Shockable Rhythm (NCT06835491) | Versailles Hospital | 2025-11-06 |
| Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE (NCT05293080) | Universitätsklinikum Hamburg-Eppendorf | 2025-11-06 |
| Comparing Haloperidol to Olanzapine in the Treatment of Suspected Cannabinoid Hyperemesis in the Emergency Department (NCT07246187) | Mercy Bon Secours Saint Vincent Medical Center | 2025-11-06 |
| DCB vs. DES in Young STEMI Patients: The DCB-STEMI Trial (NCT07229248) | National Institute of Cardiovascular Diseases, Pakistan | 2025-11-05 |
| Comparing the Safety and Efficacy of ASI-02 to Agitated Saline for Suspected Right-to-left Shunt (NCT06938347) | Agitated Solutions, Inc. | 2025-11-05 |
| Levothyroxine as Adjuvant to a Hypocaloric Diet for the Treatment of Obesity. (NCT07332273) | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | 2025-11-05 |
| Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide (NCT07220759) | Novo Nordisk A/S | 2025-11-05 |
| Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) (NCT07007065) | AbbVie | 2025-11-05 |
| Intraperitoneal Paclitaxel and Systemic Therapy Versus Systemic Therapy Alone in Gastric Cancer Patients With Peritoneal Metastasis (NCT07304271) | Magnus Nilsson | 2025-11-05 |
| Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide (NCT07220642) | Novo Nordisk A/S | 2025-11-05 |
| Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer (NCT07061977) | National Cancer Institute (NCI) | 2025-11-05 |
| Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01) (NCT07100080) | Bristol-Myers Squibb | 2025-11-05 |
| Topical Cannabidiol Lotion for Pruritus Relief in Scleroderma (NCT07245238) | Khon Kaen University | 2025-11-05 |
| Counterpain PXM Versus Diclofenac Versus Piroxicam (NCT07475663) | Taisho Pharmaceutical Indonesia | 2025-11-04 |
| Suzetrigine in Total Hip Arthroplasty (NCT07226700) | Hospital for Special Surgery, New York | 2025-11-03 |
| Pandemic Influenza Vaccine in Organ Transplantation (PIVOT Trial) (NCT07240558) | University Health Network, Toronto | 2025-11-03 |
| A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa (NCT07287644) | Bluefin Biomedicine, Inc. | 2025-11-03 |
| Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer (NCT07085767) | Olema Pharmaceuticals, Inc. | 2025-11-03 |
| Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder (NCT07123467) | Wayne State University | 2025-11-03 |
| CHinese ischEmic Stroke Beyond 4.5 Hours With TeNecteplase Under Optimized Non-Contrast CT Selection (NCT06994975) | Huashan Hospital | 2025-11-03 |
| Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma (NCT07100730) | Telix Pharmaceuticals (Innovations) Pty Limited | 2025-11-02 |
| Tenecteplase vs Medical Management in 4.5-24h LVO no Access to EVT (NCT07168278) | The First Affiliated Hospital of University of Science and Technology of China | 2025-11-01 |
| Optimal Treatment Duration for Radiographically Apparent, Bacteriologically Unconfirmed TB, Identified Through Active Case Finding (RADIO-TB Trial) (NCT07163143) | University College, London | 2025-11-01 |
| The Impact of Intraoperative Methadone on Postoperative Opioid Use (NCT07092475) | University of Utah | 2025-11-01 |
| Systematic Approach for Children With Orbital Malformation With Sirolimus Use (NCT07378657) | Ain Shams University | 2025-11-01 |
| Improving Survivorship for Critically Ill Patients Aged 65 and Over (NCT07175961) | Australian and New Zealand Intensive Care Research Centre | 2025-11-01 |
| Magnesium Sulfate Versus Lidocaine as Additives to Dexmedetomidine for Cough Suppression After Functional Endoscopic Sinus Surgery (NCT07213037) | Assiut University | 2025-11-01 |
| The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament (NCT06207253) | British University In Egypt | 2025-11-01 |
| Brentuximab Vedotin in CutAneous T-cell Lymphomas (CTCL): Post-allogeneic Hematopoietic Stem Cell Transplant Maintenance (NCT07178457) | Assistance Publique - Hôpitaux de Paris | 2025-11-01 |
| A Study of the Efficacy and Safety of BCD-281 in Patients With Relapsing-Remitting Multiple Sclerosis (NCT07321093) | Biocad | 2025-11-01 |
| Evaluation of Oral Corticosteroid Therapy in Idiopathic Sudden Unilateral Hearing Loss. (NCT07067801) | Centre Hospitalier Universitaire de Besancon | 2025-11-01 |
| Secondary Prevention of Clostridioides Difficile Using Vancomycin (NCT06979609) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2025-11-01 |
| Efficacy and Safety of AG2001 in Patients With Acute Bronchitis (NCT07198347) | Ahn-Gook Pharmaceuticals Co.,Ltd | 2025-11-01 |
| Evaluation of the Efficacy and Safety of TQB2825 Injection Compared to Immunotherapy in the Treatment of Recurrent/Refractory Follicular Lymphoma (NCT07187960) | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | 2025-11-01 |
| Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer. (NCT07216742) | Granata Bio Corporation | 2025-11-01 |
| A Study to Investigate the Effectiveness, Safety, and Tolerability of MAG200 Solution for Intra-articular Injection Compared With Placebo in Participants Aged 35 to 75 Years of Age With Symptomatic Osteoarthritis of the Knee. (NCT07106229) | Magellan Stem Cells | 2025-11-01 |
| Piflufolastat F 18 PET/CT in Patients With Suspected, or at High Risk for Metastatic ccRCC (NCT07084909) | Lantheus Medical Imaging | 2025-11-01 |
| Clinical Study in Adult Patients With Purulent-inflammatory Processes of the Skin and Soft Tissues, Phase I-II of the Wound Process (NCT06232421) | Research Institute for Physical Chemical Problems of the Belarusian State University | 2025-11-01 |
| A Phase III Study of NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients (NCT07177859) | Nanjing Chia-tai Tianqing Pharmaceutical | 2025-11-01 |
| Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System (NCT07225478) | Colgate Palmolive | 2025-10-31 |
| Prevention of Delayed CINV After Autologous Transplant: Olanzapine-Containing Regimen vs. Dexamethasone-Containing Regimen (NCT07413809) | The Affiliated People's Hospital of Ningbo University | 2025-10-31 |
| Cognitive Strategies in Early Psychosis 1 (NCT07231497) | University of Minnesota | 2025-10-31 |
| Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease (NCT07223593) | Eli Lilly and Company | 2025-10-31 |
| Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations (NCT07291037) | AstraZeneca | 2025-10-31 |
| To Evaluate The Safety and Efficacy of STSA-1002 Injection in Patients With Acute Respiratory Distress Syndrome (NCT07208591) | Staidson (Beijing) Biopharmaceuticals Co., Ltd | 2025-10-31 |
| Trial to Evaluate Immunogenicity Non-Inferiority, Safety and Lot-to-Lot Consistency of Biovac OCV-S to Euvichol®-Plus (NCT07304284) | International Vaccine Institute | 2025-10-31 |
| Camrelizumab and Apatinib With or Without FOLFOX Chemotherapy for Advanced HCC (NCT07267806) | Linhui Peng | 2025-10-31 |
| Lignin in Treatment of Helicobacter Pylori Infection (NCT07246681) | Zagazig University | 2025-10-31 |
| A Study of AND017 to Evaluate Efficacy and Safety in Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Patients With Anemia (NCT07494409) | Kind Pharmaceuticals LLC | 2025-10-31 |
| REmission in Membranous Nephropathy International Trial (REMIT) (NCT06120673) | The University of Queensland | 2025-10-31 |
| Acotiamide vs Itopride in Postprandial Distress Syndrome (NCT07174297) | Getz Pharma | 2025-10-30 |
| Interleukin-6 Receptor Inhibition for Symptomatic Intracranial Atherosclerosis (NCT06447701) | Zhujiang Hospital | 2025-10-30 |
| A Study of SHR-A2009 Combined With Aumolertinib Versus Aumolertinib for First-line Treatment in EGFR-mutated, Advanced or Metastatic NSCLC (NCT07183189) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-10-30 |
| A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19 (NCT07222384) | BioNTech SE | 2025-10-30 |
| Re-Radiochemotherapy and Pembrolizumab vs. Immuno(Chemo)Therapy for Locoregionally Recurrent PD-L1 Positive (CPS≥1) HNSCC (NCT07026474) | Universität des Saarlandes | 2025-10-30 |
| PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury (NCT06819592) | The George Institute | 2025-10-30 |
| Evaluation of Analgesia for Spine Fusion Elective Surgery in Children (NCT06626503) | Senthil Sadhasivam | 2025-10-30 |
| ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer (NCT07173751) | BioNTech SE | 2025-10-30 |
| An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE) (NCT07217860) | Xenon Pharmaceuticals Inc. | 2025-10-30 |
| A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer (NCT07205822) | AstraZeneca | 2025-10-30 |
| SPI-1005 for the Treatment of Meniere's Disease (Open Label) (NCT06859788) | Sound Pharmaceuticals, Incorporated | 2025-10-29 |
| A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus Given to Chinese Adults 18 to 59 Years of Age at Increased Risk of Respiratory Syncytial Virus Disease (NCT07220109) | GlaxoSmithKline | 2025-10-29 |
| PKB171 Against Placebo in Couples With Mild Male Factor Infertility (NCT07669584) | Prokrea BCN, S.L. | 2025-10-28 |
| Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients (NCT06934967) | Novartis Pharmaceuticals | 2025-10-28 |
| The Efficacy and Safety of Intramuscular Methylprednisolone in Patients With Hand OsteoArthritis (NCT07371572) | Sint Maartenskliniek | 2025-10-28 |