| Jaktinib Versus Hydroxycarbamide in Subjects With Intermediate-2 or High-risk Myelofibrosis (NCT04617028) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2021-02-05 |
| Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease (NCT03770663) | Assistance Publique - Hôpitaux de Paris | 2021-02-05 |
| A Study of Long-Term Safety and Efficacy of Lanadelumab for Prevention of Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (NCT04444895) | Shire | 2021-02-05 |
| A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors (NCT04431726) | Hoffmann-La Roche | 2021-02-04 |
| VTE Prevention Following Total Hip and Knee Arthroplasty (NCT04075240) | Sudeep Shivakumar | 2021-02-04 |
| A Study to Evaluate the Esophageal Stenosis Inhibition Effects of CLS2702C/CLS2702D After Endoscopic Submucosal Dissection (ESD) in Patients With Superficial Esophageal Cancer in the Steroid Administration Risk Group (NCT04689594) | CellSeed Inc. | 2021-02-04 |
| Effect of SHR8058 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (NCT05515471) | Jiangsu HengRui Medicine Co., Ltd. | 2021-02-04 |
| A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule as Second-line Treatment in Subjects With Advanced Biliary Cancer (NCT04809142) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-02-04 |
| A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype (NCT04718103) | GlaxoSmithKline | 2021-02-04 |
| A Study to Evaluate Rozanolixizumab in Study Participants With Generalized Myasthenia Gravis (NCT04650854) | UCB Biopharma SRL | 2021-02-03 |
| Epidural Stimulation and Resistance Training After SCI (NCT04782947) | United States Department of Defense | 2021-02-03 |
| Effects of Low Molecular Weight Heparin Therapy With Soft-Mist Inhaler for COVID-19 Induced Hypoxemia (NCT04990830) | Istanbul University | 2021-02-03 |
| Efficacy and Safety of DWJ1248 With Remdesivir in Severe COVID-19 Patients (NCT04713176) | Daewoong Pharmaceutical Co. LTD. | 2021-02-02 |
| Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway (NCT04736589) | Peking Union Medical College | 2021-02-02 |
| DEB-TACE Plus Lenvatinib or Sorafenib or PD-1 Inhibitor for Unresectable Hepatocellular Carcinoma (NCT04229355) | Guangxi Medical University | 2021-02-02 |
| Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients (NCT03127267) | AB Science | 2021-02-02 |
| Adjuvant Entecavir or Tenofovir for Postoperative HBV-HCC (NCT02650271) | Guangxi Medical University | 2021-02-02 |
| BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension (NCT03235232) | EMS | 2021-02-01 |
| Study of the Safety and Efficacy of Nabiximols Oromucosal Spray Versus Placebo in Patients With Post-traumatic Stress Disorder (NCT04592159) | Jazz Pharmaceuticals | 2021-02-01 |
| Intra-articular Corticosteroid Injections to Platelet Rich Plasma (PRP) for Cervical Facetogenic Pain (NCT04392999) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-02-01 |
| Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache (NCT04905953) | Cairo University | 2021-02-01 |
| Nabilone for Agitation Blinded Intervention Trial (NCT04516057) | Sunnybrook Health Sciences Centre | 2021-02-01 |
| Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility (NCT04748796) | Centre Hospitalier Universitaire, Amiens | 2021-02-01 |
| DYNAMIC Study (DoxycYcliNe AMbulatoIre COVID-19) (NCT04371952) | Nantes University Hospital | 2021-02-01 |
| Avatrombopag Usage in NSAA (NCT04728789) | Peking Union Medical College Hospital | 2021-02-01 |
| Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR) (NCT05508152) | Hospital de Granollers | 2021-02-01 |
| Nomacopan (rVA576) in Transplant Associated Thrombotic Microangiopathy (NCT04784455) | AKARI Therapeutics | 2021-02-01 |
| Evaluate the Efficacy and Safety of DWJ1506 and DWJ1507 (NCT04772443) | Daewoong Pharmaceutical Co. LTD. | 2021-02-01 |
| A Trial of Procalcitonin in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease (NCT04682899) | Capital Medical University | 2021-02-01 |
| Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder (NCT04578756) | AbbVie | 2021-02-01 |
| A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain (NCT04504812) | Johns Hopkins University | 2021-02-01 |
| Iron Supplementation and Neurodevelopmental Outcome in ELGANs (NCT04691843) | Ann & Robert H Lurie Children's Hospital of Chicago | 2021-02-01 |
| Trial Comparing Impact of PENG Block on Quality of Recovery Compared to No-block for Primary Total Hip Arthroplasty (NCT04591353) | University of Alabama at Birmingham | 2021-02-01 |
| Efficacy and Safety of UC-MSCs for the Treatment of Steroid-resistant aGVHD Following Allo-HSCT (NCT04738981) | Peking University People's Hospital | 2021-02-01 |
| Effects Of Acute Supplementation Of Citrus Aurantium L. On The Recovery Of Autonomic And Cardiovascular Activity After A Sub-Maximum Aerobic Exercise Session In Healthy Individuals (NCT04875143) | University of Pernambuco | 2021-02-01 |
| Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (NCT04079231) | Novartis Pharmaceuticals | 2021-02-01 |
| Ultrasound-guided Regional Anesthesia vs Local Infiltration Anesthesia With Dexmedetomidine and Ropivacaine (NCT04697537) | Medical University of Graz | 2021-02-01 |
| An Extension Study to Assess Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-4) (NCT04659174) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2021-02-01 |
| A Study to Evaluate SHR-1210 in Combination With Famitinib Plus Chemotherapy in Subjects With NSCLC. (NCT04619433) | Jiangsu HengRui Medicine Co., Ltd. | 2021-02-01 |
| Enhancing Protection Against Vector-borne Diseases in Forcibly Displaced Communities: Evaluating the Efficacy of Spatial Repellents for Cutaneous Leishmaniasis Control in North-East Syria (NCT06917040) | The Mentor Initiative | 2021-02-01 |
| Effectiveness and Safety of Platelet Rich Plasma (PRP) on Persistent Olfactory Dysfunction Related to COVID-19 (NCT05226546) | Centre Hospitalier Universitaire Saint Pierre | 2021-02-01 |
| A Phase III Long Term Study of K-877 Extended Release Tablet (NCT04716595) | Kowa Company, Ltd. | 2021-02-01 |
| A Phase III Confirmatory Study of K-877 Extended Release Tablet (NCT04714151) | Kowa Company, Ltd. | 2021-02-01 |
| Comparison of Efficacy Between 100% Platelet-rich Plasma and 100% Serum Eye Drops in Dry Eye Disease (NCT04683796) | Mahidol University | 2021-02-01 |
| Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension (NCT04686643) | Ahn-Gook Pharmaceuticals Co.,Ltd | 2021-02-01 |
| A Study to Evaluate the Safety, Immunogenicity, and Efficacy of UB-612 COVID-19 Vaccine (NCT04683224) | Vaxxinity, Inc. | 2021-02-01 |
| Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients (NCT05638893) | Tanta University | 2021-02-01 |
| Clinical Efficacy of Adjuvant Chemotherapy in Patients With Locally Advanced Cervical Cancer Who Did Not Meet the NCCN Guidelines for Adjuvant Treatment After NACT Combined With Surgery (NCT04733820) | Huazhong University of Science and Technology | 2021-02-01 |
| Proxalutamide Treatment for Hospitalized COVID-19 Patients (NCT04728802) | Applied Biology, Inc. | 2021-02-01 |
| An Investigator Initiated Prospective, Four Arms Randomized Comparative Study of Efficacy and Safety of Saroglitazar, Vitamin E and Life Style Modification in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)/ Non-alcoholic Steatohepatitis (NASH) (NCT04193982) | Asian Institute of Gastroenterology, India | 2021-01-31 |
| A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS) (NCT04624659) | Forma Therapeutics, Inc. | 2021-01-29 |
| Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment (NCT03527069) | EMS | 2021-01-29 |
| Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure (NCT04410042) | St. Jude Children's Research Hospital | 2021-01-29 |
| Phase 3 Trial to Evaluate the Efficacy and Safety of YYC506. (NCT04858308) | Yooyoung Pharmaceutical Co., Ltd. | 2021-01-29 |
| A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder (NCT04693351) | Biohaven Pharmaceuticals, Inc. | 2021-01-29 |
| The Neoadjuvant Combined Hormone Therapy in Premenopausal Women With Locally Advanced ER+/HER2- Breast Cancer (NCT04753177) | Saint Petersburg State Budgetary Healthcare Institution, City Clinical Oncology Dispensary | 2021-01-28 |
| Household-level Impact of IPT of Malaria in Schoolchildren (NCT04660110) | Makerere University | 2021-01-28 |
| Efficacy and Safety of SKCPT in Patients With Knee Osteoarthritis: Phase III Clinical Trial (NCT05930080) | SK Chemicals Co., Ltd. | 2021-01-28 |
| A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease (NCT04711252) | AstraZeneca | 2021-01-28 |
| Brain Activation and Satiety in Children 2 (NCT04520490) | Seattle Children's Hospital | 2021-01-28 |
| The Efficacy, Safety and Immunogenicity Study of Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19 (NCT04659239) | Chinese Academy of Medical Sciences | 2021-01-28 |
| Postoperative Adjuvant Chemotherapy in Early-stage Cervical Cancer That Not Meet Criteria of Adjuvant Therapeutic According to NCCN Guideline (NCT04723875) | Huazhong University of Science and Technology | 2021-01-28 |
| Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults (NCT04723394) | AstraZeneca | 2021-01-28 |
| Prevention of Atrial Fibrillation by Low-dose Landiolol Administration After Cardiac Surgery (NCT04607122) | CMC Ambroise Paré | 2021-01-27 |
| Prebiotics for Spinal Cord Injury Patients With Bowel and Bladder Dysfunction (NCT03987126) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-01-27 |
| Local Antibiotics for Breast Implants (NCT04731025) | Mikkel Herly | 2021-01-27 |
| Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (NCT04773587) | Arcutis Biotherapeutics, Inc. | 2021-01-27 |
| CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks (NCT04656418) | CSL Behring | 2021-01-27 |
| The COVID-RASi Trial (COVID-19) (NCT04591210) | Ottawa Heart Institute Research Corporation | 2021-01-27 |
| Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia (NCT04652726) | Novartis Pharmaceuticals | 2021-01-27 |
| Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Following Progression on First Line CDK 4/6 Inhibitor and Aromatase Inhibitor (NCT04650581) | Canadian Cancer Trials Group | 2021-01-27 |
| A Study to Evaluate the Safety, Tolerability, and Efficacy of Long-Term Gantenerumab Administration in Participants With Alzheimer's Disease (AD) (NCT04374253) | Hoffmann-La Roche | 2021-01-26 |
| Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF (NCT04627025) | VectivBio AG | 2021-01-26 |
| A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype (NCT04718389) | GlaxoSmithKline | 2021-01-26 |
| A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease (NCT04735393) | Aldeyra Therapeutics, Inc. | 2021-01-26 |
| A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular Degeneration (NCT04239027) | Novartis Pharmaceuticals | 2021-01-26 |
| Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New World (NCT04515186) | Drugs for Neglected Diseases | 2021-01-26 |
| The Efficacy of Patients With Moderate to Severe Atopic Dermatitis Treated With Chinese Herbal Medicine (NCT04686955) | Taipei Veterans General Hospital, Taiwan | 2021-01-25 |
| Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment (NCT04558918) | Novartis Pharmaceuticals | 2021-01-25 |
| Metformin for the Treatment of Hidradenitis Suppurativa (HS) (NCT04649502) | K.R. van Straalen | 2021-01-25 |
| A Study to Evaluating the Efficacy and Safety of Recombinant Long-acting Human Growth Hormone (TJ101) in Children With Growth Hormone Deficiency (NCT04633057) | TJ Biopharma Co., Ltd. | 2021-01-25 |
| Dexamethasone for Post Uterine Artery Embolization Pain (NCT04655144) | University of Miami | 2021-01-25 |
| Or v IV Antibiotics for Infection (NCT04723940) | Rothman Institute Orthopaedics | 2021-01-25 |
| Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia (NCT04724044) | Hellenic Institute for the Study of Sepsis | 2021-01-25 |
| The (HD)IVACOV Trial (The High-Dose IVermectin Against COVID-19 Trial) (NCT04712279) | Corpometria Institute | 2021-01-25 |
| Prehabilitation in Gynaecological Cancer Patients (NCT04789694) | Charles University, Czech Republic | 2021-01-25 |
| Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults (NCT04530565) | National Cancer Institute (NCI) | 2021-01-25 |
| Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients (NCT04578834) | Novartis Pharmaceuticals | 2021-01-25 |
| Immunogenicity and Safety Study of GSK's MenABCWY Vaccine in Healthy Adolescents and Adults Previously Primed With MenACWY Vaccine (NCT04707391) | GlaxoSmithKline | 2021-01-25 |
| A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR) (NCT04576988) | Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA | 2021-01-25 |
| Saphenous Nerve Block for Partial Meniscectomy (NCT04717609) | Rothman Institute Orthopaedics | 2021-01-25 |
| Does Meloxicam Provide as Much Pain Relief as Opioids After Shoulder Surgery? (NCT04725357) | Rothman Institute Orthopaedics | 2021-01-25 |
| Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ) (NCT04134052) | Universidad de Colima | 2021-01-24 |
| Melatonin for Prevention of Postoperative Delirium After Lower Limb Fracture Surgery in Elderly Patients (NCT04335968) | Assistance Publique - Hôpitaux de Paris | 2021-01-23 |
| Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial (NCT04683042) | Kathleen Sluka | 2021-01-22 |
| Multicenter Double Blind, Parallel-group Phase 2/3 Trial, to Study Raloxifene in Adult COVID-19 Patients. (NCT05172050) | Dompé Farmaceutici S.p.A | 2021-01-22 |
| Prevention and Treatment for COVID -19 (Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2) Associated Severe Pneumonia in the Gambia (NCT04703608) | London School of Hygiene and Tropical Medicine | 2021-01-22 |
| The Study is Being Conducted to Evaluate the Efficacy and Safety of SHR-1316 in Combination With Chemo-radiotherapy in Patients With LS-SCLC. (NCT04691063) | Jiangsu HengRui Medicine Co., Ltd. | 2021-01-22 |
| CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19 (NCT04516941) | Insel Gruppe AG, University Hospital Bern | 2021-01-21 |
| Comparison of Oral Ferrous Sulfate to Intravenous Ferumoxytol in Antepartum Iron Deficiency Anemia (NCT04253626) | Stanford University | 2021-01-21 |