| Exercise, Milk Thistle, and Lactobacillus to Influence Plasma Bilirubin (NCT04717726) | Kyle Flack | 2021-02-24 |
| CMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced Melanoma (NCT04695977) | Regeneron Pharmaceuticals | 2021-02-24 |
| Spironolactone and Dexamethasone in Patients Hospitalized With COVID-19 (NCT04826822) | Chita State Regional Clinical Hospital Number 1 | 2021-02-24 |
| Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel (Neuronata-R® Inj.) Treatment in Patients With ALS (NCT04745299) | Corestemchemon, Inc. | 2021-02-24 |
| Open-label Trial in Parkinson's Disease (PD) (NCT04760769) | AbbVie | 2021-02-24 |
| Comparison of Chemotherapy Before and After Surgery Versus After Surgery Alone for the Treatment of Gallbladder Cancer (NCT04559139) | ECOG-ACRIN Cancer Research Group | 2021-02-24 |
| Pronase Granules in Gastric Cleaning (NCT05249933) | Changhai Hospital | 2021-02-24 |
| Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older (NCT04762680) | Sanofi Pasteur, a Sanofi Company | 2021-02-24 |
| Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial (NCT04566328) | ECOG-ACRIN Cancer Research Group | 2021-02-24 |
| Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-II) (NCT04773600) | Arcutis Biotherapeutics, Inc. | 2021-02-24 |
| Oral ISL QM as PrEP in Cisgender Women at High Risk for HIV-1 Infection (MK-8591-022) (NCT04644029) | Merck Sharp & Dohme LLC | 2021-02-24 |
| Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD (NCT03984188) | University of Miami | 2021-02-23 |
| Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate Cancer (NCT04736199) | Bayer | 2021-02-23 |
| Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation (NCT04685135) | Mirati Therapeutics Inc. | 2021-02-23 |
| Long-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia A (NCT04644575) | Bioverativ, a Sanofi company | 2021-02-23 |
| A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer (NCT03899636) | Angiodynamics, Inc. | 2021-02-23 |
| Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV (NCT04255849) | Weill Medical College of Cornell University | 2021-02-23 |
| A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (NCT04408638) | Hoffmann-La Roche | 2021-02-23 |
| Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT (NCT04702373) | Carelon Research | 2021-02-23 |
| Profiling Antibody Status and Vaccine Effectiveness in Post Vaccination With SARS CoV2 in Ain Shams University (NCT04885764) | Ain Shams University | 2021-02-23 |
| Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer (NCT04697628) | Seagen, a wholly owned subsidiary of Pfizer | 2021-02-22 |
| A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis (NCT04753697) | Celgene | 2021-02-22 |
| Subcutaneous Injection of Large Volumes of Tumescent Lidocaine and Epinephrine by Laypersons (NCT04733781) | Jeffrey Alan Klein, MD | 2021-02-22 |
| Study to Demonstrate Consistency of Three Lots of a Live-attenuated Chikungunya Virus Vaccine Candidate in Healthy Adults (NCT04786444) | Valneva Austria GmbH | 2021-02-22 |
| A Phase III Trial of Z-338 in Paediatric Patients With Functional Dyspepsia (NCT04526119) | Zeria Pharmaceutical | 2021-02-22 |
| Midodrine Versus Albumin for Prevention of Paracentesis Induced Circulatory Disturbance (NCT05240391) | Asian Institute of Gastroenterology, India | 2021-02-20 |
| Effect of Upstream Treatment With High Intensity Statin on the Outcomes of STMI Patients Treated With PPCI (NCT04754789) | Assiut University | 2021-02-20 |
| Study to Evaluate Efficacy, Immunogenicity and Safety of the Sputnik-Light (NCT04741061) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2021-02-19 |
| A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer (NCT04688931) | UroGen Pharma Ltd. | 2021-02-19 |
| A Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the Prevention of Chronic or Episodic Migraine (NCT04686136) | AbbVie | 2021-02-19 |
| Esketamine and Perioperative Depressive Symptoms (NCT04425473) | Beijing Tiantan Hospital | 2021-02-19 |
| Safety & Efficacy of Low Dose Aspirin / Ivermectin Combination Therapy for Treatment of Covid-19 Patients (NCT04768179) | Makerere University | 2021-02-19 |
| PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V (NCT04870333) | Cambridge University Hospitals NHS Foundation Trust | 2021-02-19 |
| Safety, Efficacy and PK of BIVV001 in Pediatric Patients With Hemophilia A (NCT04759131) | Bioverativ, a Sanofi company | 2021-02-19 |
| Study To Assess Adverse Events and Change in Disease Activity Of 24-hour Continuous Subcutaneous Infusion Of ABBV-951 In Adult Participants With Advanced Parkinson's Disease (NCT04750226) | AbbVie | 2021-02-18 |
| DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma (NCT04334759) | PrECOG, LLC. | 2021-02-18 |
| Eptinezumab in Adults With Migraine and Medication Overuse Headache (NCT04772742) | H. Lundbeck A/S | 2021-02-17 |
| Sisonke (Together): OPEN LABEL TRIAL COVID-19 (NCT04838795) | Wits Health Consortium (Pty) Ltd | 2021-02-17 |
| Open Multicentre Study of the Safety and Efficacy Against COVID-19 of Nirmatrelvir/Ritonavir in the Adult Population (NCT05601167) | Promomed, LLC | 2021-02-17 |
| Favipiravir in High-risk COVID-19 Patients (NCT04818320) | Penang Hospital, Malaysia | 2021-02-16 |
| Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction (NCT04764916) | Carilion Clinic | 2021-02-16 |
| Trial of Tolerability, Safety and Immunogenicity of the Flu-M Vaccine in Children Between 6 Months and 9 Years Old (NCT05470582) | St. Petersburg Research Institute of Vaccines and Sera | 2021-02-16 |
| Upamostat, a Serine Protease Inhibitor, or Placebo for Treatment of COVID-19 Disease (NCT04723537) | RedHill Biopharma Limited | 2021-02-16 |
| A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism (NCT04701203) | Ascendis Pharma Bone Diseases A/S | 2021-02-16 |
| Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia (NCT04659863) | Novartis Pharmaceuticals | 2021-02-16 |
| To Evaluate the Safety, Tolerability, and Immunogenicity of BNT162b2 Against COVID-19 in Healthy Pregnant Women 18 Years of Age and Older (NCT04754594) | BioNTech SE | 2021-02-16 |
| A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma (NCT04576117) | National Cancer Institute (NCI) | 2021-02-16 |
| A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones (NCT04387617) | Mayo Clinic | 2021-02-15 |
| The Potential Protective Role of Venlafaxine Versus Memantine in Paclitaxel Induced Peripheral Neuropathy (NCT04737967) | Mendel AI | 2021-02-15 |
| Antiviral Agents Against COVID-19 Infection (NCT04468087) | Hospital do Coracao | 2021-02-15 |
| Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 (NCT04360096) | APR Applied Pharma Research s.a. | 2021-02-15 |
| A Phase 3 Study to Evaluate the Safety, Tolerability, and Immunogenicity of Multiple Production Lots and Dose Levels of BNT162b2 RNA-Based COVID-19 Vaccines Against COVID-19 in Healthy Participants (NCT04713553) | BioNTech SE | 2021-02-15 |
| Immunogenicity, Safety, Reactogenicity and Persistence of an Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above (NCT04732871) | GlaxoSmithKline | 2021-02-15 |
| Pharmacogenetics of Torasemide and Spironolactone in Hypertension Treatment (NCT06413082) | Ospedale San Raffaele | 2021-02-15 |
| Use of Hypochlorous Acid as Prophylaxis in Health Personnel at High Risk of Infection by SARS-CoV 2 (COVID19) (NCT04684550) | Hospital Universitario San Ignacio | 2021-02-15 |
| Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy (NCT04379570) | Alliance for Clinical Trials in Oncology | 2021-02-15 |
| White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial (NCT04994314) | University of Baghdad | 2021-02-15 |
| COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis (NCT04650087) | Thomas L. Ortel | 2021-02-15 |
| Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy (NCT04356326) | Centre Hospitalier Intercommunal Creteil | 2021-02-15 |
| Pharmacological Reduction of Right Ventricular Enlargement (NCT04345796) | Asan Medical Center | 2021-02-15 |
| Study to Assess the Effect of Meplazumab on COVID-19 (NCT04586153) | Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd | 2021-02-15 |
| Use of Autologous Plasma Rich in Platelets and Extracellular Vesicles in the Surgical Treatment of Chronic Middle Ear Infections (NCT04761562) | University Medical Centre Ljubljana | 2021-02-14 |
| Study on Efficacy and Safety of Reparixin in the Treatment of Hospitalized Patients With Severe COVID-19 Pneumonia. (NCT04878055) | Dompé Farmaceutici S.p.A | 2021-02-14 |
| Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (NCT04751487) | Sanofi | 2021-02-12 |
| Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer. (NCT04648020) | Monopar Therapeutics | 2021-02-11 |
| Safety and Immunogenicity of Oxford AstraZeneca Vaccine Against COVID-19 Infection (NCT04756271) | Zagazig University | 2021-02-11 |
| Comparative Effect of Nigella Sativa and Conventional Management for OSMF (NCT04476420) | Ziauddin University | 2021-02-11 |
| Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery (NCT04711837) | Haisco-USA Pharmaceuticals, Inc. | 2021-02-11 |
| Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia (NCT04756713) | Brigham and Women's Hospital | 2021-02-11 |
| Fluoxetine vs CBT in Childhood Anxiety Disorders (NCT04760275) | Children's Hospital Los Angeles | 2021-02-10 |
| Expanded Access Program With Lanadelumab for Japanese People With Hereditary Angioedema (NCT04687137) | Takeda | 2021-02-10 |
| Statins for Venous Event Reduction in Patients With Venous Thromboembolism (NCT04319627) | Ottawa Hospital Research Institute | 2021-02-10 |
| Safety and Immunogenicity of V114 in Healthy Infants in South Korea (V114-036) (NCT04633226) | Merck Sharp & Dohme LLC | 2021-02-10 |
| Hypofractionated LocoRegional Radiotherapy in Breast Cancer (NCT04228991) | Ontario Clinical Oncology Group (OCOG) | 2021-02-10 |
| AZD7442 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial) (NCT05780437) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-02-10 |
| Partners in Caring for Anxious Youth (NCT04598230) | Ann & Robert H Lurie Children's Hospital of Chicago | 2021-02-09 |
| Long-term Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) With Venglustat (NCT04705051) | Sanofi | 2021-02-09 |
| ADORE: Efficacy of DORavirine in Adults Living With HIV Experiencing Virological Failure on First-line Efavirenz-based Antiretroviral Therapy With NNRTI Resistance (NCT04429152) | Professor Francois Venter | 2021-02-09 |
| Behavioral Mechanism of Energy Compensation With Exercise (NCT04651218) | Kyle Flack | 2021-02-09 |
| A Study of IBI306 in Participants With Hypercholesterolemia (NCT04709536) | Innovent Biologics (Suzhou) Co. Ltd. | 2021-02-09 |
| Treatment of Moderate to Severe Glabellar Lines (BMI2006) (NCT05531968) | BMI Korea | 2021-02-09 |
| Study of the Efficacy and Safety of Somatropin in Japanese Participants With PWS (NCT04697381) | Pfizer | 2021-02-09 |
| Efficacy Confirmation Study of NPC-09 (NCT04671472) | Nobelpharma | 2021-02-08 |
| Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome (NCT04797780) | Syros Pharmaceuticals | 2021-02-08 |
| ITCH Trial: Protocol for a Randomized, Double Blind Placebo-controlled Trial (NCT04742205) | Kathmandu Medical College and Teaching Hospital | 2021-02-08 |
| Impact on Atrial Remodeling of Dapaglifozin in Patients With Heart Failure . (NCT04707352) | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | 2021-02-08 |
| Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL) (NCT04574960) | University Health Network, Toronto | 2021-02-08 |
| Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure (NCT05093621) | Yale University | 2021-02-08 |
| Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure (NCT04705987) | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | 2021-02-08 |
| Azithromycin Plus Hydroxychloroquine for COVID-19 Infection (NCT05026801) | Iterum Therapeutics, International Limited | 2021-02-08 |
| PRevention of COVID-19 With Oral Vitamin D Supplemental Therapy in Essential healthCare Teams (NCT04483635) | St. Justine's Hospital | 2021-02-08 |
| Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2 (NCT04229979) | Sellas Life Sciences Group | 2021-02-08 |
| Proxalutamide Treatment for COVID-19 Patients in Intensive Care Unit (NCT04853927) | Applied Biology, Inc. | 2021-02-08 |
| ExclUsive endocRine Therapy Or Radiation theraPy for Women Aged ≥70 Years Early Stage Breast Cancer (NCT04134598) | Azienda Ospedaliero-Universitaria Careggi | 2021-02-08 |
| Clinical Trial of Dimolegin (DD217) in Prevention of Thrombotic Complications in Patients With COVID-19 (NCT05185804) | PharmaDiall Ltd. | 2021-02-08 |
| Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS) (NCT04607005) | GlaxoSmithKline | 2021-02-08 |
| A Study to Compare the Effectiveness and Safety of IBI310 Combined With Sintilimab Versus Sorafenib in the First-line Treatment of Advanced HCC (NCT04720716) | Innovent Biologics (Suzhou) Co. Ltd. | 2021-02-07 |
| Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous Meningitis (NCT04145258) | ANRS, Emerging Infectious Diseases | 2021-02-07 |
| Long-term Safety and Efficacy of Adjunctive Brivaracetam in Chinese Patients With Uncontrolled Focal Epilepsy (NCT07563634) | Jiangxi Qingfeng Pharmaceutical Co. Ltd. | 2021-02-07 |
| Evaluating the Pharmacodynamic Noninferiority of Efgartigimod PH20 SC Administered Subcutaneously as Compared to Efgartigimod Administered Intravenously in Patients With Generalized Myasthenia Gravis (NCT04735432) | argenx | 2021-02-05 |