| A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation (NCT07566052) | Astellas Pharma Global Development, Inc. | 2026-04-28 |
| A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA) (NCT07221669) | Biogen | 2026-04-28 |
| Safinamide vs Placebo for Pain in Patients With Parkinson's Disease and Motor Fluctuations (NCT07761936) | Universita di Verona | 2026-04-28 |
| Open-Label Study of Dimethyl Fumarate in Adults With Type 1 Diabetes (NCT07548996) | Nanjing Medical University | 2026-04-27 |
| Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study (NCT07516132) | Ocular Therapeutix, Inc. | 2026-04-27 |
| Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy (NCT07493057) | Gan & Lee Pharmaceuticals. | 2026-04-27 |
| A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A (NCT07416604) | Hoffmann-La Roche | 2026-04-27 |
| FMT Capsules for rCDI (NCT07458984) | Helsinki University Central Hospital | 2026-04-25 |
| Yulinzhu for Women With Diminished Ovarian Reserve (NCT07550998) | The University of Hong Kong | 2026-04-24 |
| MDT-0123 Japan Study (NCT07414745) | Medtronic Spinal and Biologics | 2026-04-24 |
| A Clinical Study on the Treatment of LACC With Cadonilimab Combined With Chemotherapy Followed by CCRT (NCT07400536) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2026-04-24 |
| A Study to Investigate NPS and Symptoms in Chinese Adult Participants With CRSwNP Initiating Treatment With Tezepelumab (NCT07520162) | AstraZeneca | 2026-04-24 |
| Effect of Semaglutide on Healing of Foot Ulcers in Type 2 Diabetes Patients (NCT07581145) | Ole Lander Svendsen | 2026-04-24 |
| A Study of Lebrikizumab in Adults With Nummular Eczema (NCT07542483) | Almirall, S.A. | 2026-04-24 |
| Vancomycin Taper to Prevent Recurrent Clostridioides Difficile (NCT07328971) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2026-04-24 |
| Efficacy and Safety of IBI362 in Hypertensive Patients With Overweight/Obesity (NCT07469800) | Innovent Biologics (Suzhou) Co. Ltd. | 2026-04-23 |
| ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL (NCT07342478) | Newave Pharmaceutical Inc | 2026-04-23 |
| Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications (NCT07565428) | Minerva Neurosciences | 2026-04-23 |
| A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031) (NCT07419295) | Merck Sharp & Dohme LLC | 2026-04-23 |
| A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD (NCT07285655) | Liquidia Technologies, Inc. | 2026-04-23 |
| 52-week Open Label Safety-Tolerability Study (NCT07369154) | LB Pharmaceuticals Inc. | 2026-04-23 |
| A Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex in Participants With Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma (NCT07582432) | Grifols Biologicals, LLC | 2026-04-23 |
| An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH) (NCT07365332) | Inhibikase Therapeutics | 2026-04-23 |
| Ongericimab Injection Reducing Recurrence of Ischemic Stroke (NCT07242599) | Beijing Tiantan Hospital | 2026-04-22 |
| Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Posterior Circulation Large Vessel Occlusion Stroke (NCT07509645) | Capital Medical University | 2026-04-22 |
| A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer (NCT07365995) | BioNTech SE | 2026-04-22 |
| A Study to Test the Effects and Safety of Palopegteriparatide in Adolescents With Long-term Hypoparathyroidism (NCT07706764) | Ascendis Pharma A/S | 2026-04-22 |
| A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2 (NCT07502443) | Alkermes, Inc. | 2026-04-22 |
| A Phase III Study to Evaluate the Efficacy and Safety of Libevitug in Participants With Chronic HDV Infection (D-clear Study) (NCT07499544) | Huahui Health | 2026-04-22 |
| Clinical Study to Compare Efficacy and Safety of AVT29 and Eylea HD in Participants With Diabetic Macular Edema (NCT07489131) | Alvotech Swiss AG | 2026-04-22 |
| Donidalorsen Treatment in Children With Hereditary Angioedema (NCT07298447) | Ionis Pharmaceuticals, Inc. | 2026-04-21 |
| A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease (NCT07499232) | Janssen Research & Development, LLC | 2026-04-21 |
| Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients. (NCT07319208) | Nantes University Hospital | 2026-04-21 |
| AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss (NCT07503210) | Novo Nordisk A/S | 2026-04-21 |
| Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial (NCT05379153) | Alliance for Clinical Trials in Oncology | 2026-04-21 |
| Study to Evaluate the Therapeutic Equivalence and Safety of Fluticasone Furoate and Vilanterol Inhalation Powder 100 mcg/25 mcg and BREO ELLIPTA 100 mcg/25 mcg in Participants With Asthma (NCT07223294) | Sandoz | 2026-04-21 |
| Continuous Antibiotic Infusion In Children (NCT07575009) | Tampere University Hospital | 2026-04-21 |
| Ivabradine in the Acute Management of Cardiogenic Shock (NCT07714746) | National Institute of Cardiovascular Diseases, Pakistan | 2026-04-20 |
| AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain (NCT07509307) | Novo Nordisk A/S | 2026-04-20 |
| Phase III Clinical Trial of Telitacicept Injection in the Treatment of Patients With Connective Tissue Disease-related Interstitial Lung Disease (NCT07495033) | RemeGen Co., Ltd. | 2026-04-20 |
| Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty. (NCT07582835) | Cardiocentro Ticino | 2026-04-20 |
| Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity (NCT07476443) | Ain Shams University | 2026-04-20 |
| Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer (NCT07528209) | Sun Yat-sen University | 2026-04-20 |
| Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty (NCT06902714) | University of Alabama at Birmingham | 2026-04-20 |
| OLE Study With Filgotinib in JIA (NCT07553182) | Alfasigma S.p.A. | 2026-04-20 |
| A Seamless Phase II/III, Observer-blind, to Evaluate Immunogenicity and Safety of Chikungunya Virus Vaccine in Healthy Subjects 12-65Years of Age. (NCT07555392) | Bharat Biotech International Limited | 2026-04-20 |
| QLC5508 vs. Chemotherapy in Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (NCT07463573) | Qilu Pharmaceutical Co., Ltd. | 2026-04-20 |
| Safety and Efficacy Study of QL0911 to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients (NCT07455006) | Qilu Pharmaceutical Co., Ltd. | 2026-04-20 |
| Transcutaneous Electrical Acupoint Stimulation at Jing-Well Points for Disorders of Consciousness (NCT07535593) | Xijing Hospital | 2026-04-20 |
| Prehospital Pulse-dose Glucocorticoid in Patients With ST-segment Elevation Myocardial Infarction 2 - The PULSE-MI 2 Trial (NCT07478003) | Thomas Engstrom | 2026-04-20 |
| This is a 96-week, Multicenter Study in Patients With Neovascular AMD That Evaluates OCUL101 for Efficacy, Safety, Durability, and Pharmacokinetics, Comparing it With Another Treatment. The Study Will be Conducted in Two Parts, Part A and Part B. (NCT07520318) | Shenzhen Oculgen Biomedical Technology Co., Ltd. | 2026-04-17 |
| A Phase III Study of MG-K10 in Adolescents With Moderate-to-Severe Atopic Dermatitis (NCT07540442) | Shanghai Mabgeek Biotech.Co.Ltd | 2026-04-17 |
| A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression (NCT07546500) | K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc | 2026-04-17 |
| Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors (NCT07444723) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2026-04-16 |
| Visugromab in Cachexia International Trial (NCT07112196) | CatalYm GmbH | 2026-04-16 |
| Remibrutinib Open Label Roll-over Post-trial Access Protocol (NCT07456891) | Novartis Pharmaceuticals | 2026-04-16 |
| A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia (NCT07286032) | Jiangsu HengRui Medicine Co., Ltd. | 2026-04-16 |
| A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) or Microvascular Inflammation (MVI) (TRANSCEND/TRANSPIRE LTE) (NCT07444489) | Biogen | 2026-04-16 |
| A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation (NCT07487818) | Mayo Clinic | 2026-04-15 |
| A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis (NCT07158242) | Hoffmann-La Roche | 2026-04-15 |
| Study of Nogapendekin Alfa Inbakicept and iNKT Cells in Critically Ill Adults With Severe Community-Acquired Pneumonia (NCT07492875) | ImmunityBio, Inc. | 2026-04-15 |
| Endoscopic Ultrasound-Guided Loco-regional Chemotherapy Injection as Adjuvant Therapy for Locally Advanced Pancreatic Cancer. (NCT07429643) | Assiut University | 2026-04-15 |
| A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) (NCT07496567) | EyeBiotech Ltd. | 2026-04-15 |
| Clinical Study on the Efficacy and Safety of LM-302 Injection Combined With Tislelizumab and Tislelizumab Combined Chemotherapy for the Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma. (NCT07385703) | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | 2026-04-15 |
| Impact on Delirium of the Use of DEXmedetomidine as First-line Sedation in PEDIAtric Intensive Care (NCT07542990) | University Hospital, Tours | 2026-04-15 |
| Improving Postoperative Analgesia After Functional Endoscopic Surgery (NCT07555821) | South Egypt Cancer Institute | 2026-04-15 |
| Comparison of the Therapeutic Effects of Methylprednisolone and Dexamethasone on Peritumoral Edema During Radiotherapy for Brain Metastases: (NCT07542288) | The Second Affiliated Hospital of Hainan Medical University | 2026-04-15 |
| Virtual Menstrual Pain Approaches in Females (NCT07497711) | Nanyang Technological University | 2026-04-15 |
| Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer (NCT07412613) | Akeso | 2026-04-15 |
| A Study of MG-K10 in Chronic Spontaneous Urticaria (NCT07546487) | Shanghai Mabgeek Biotech.Co.Ltd | 2026-04-14 |
| The POWER Trial: Personalised Dose Optimisation With Adjuvant Tamoxifen Therapy in Breast cancER (NCT07502820) | Karolinska Institutet | 2026-04-14 |
| Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) On-Demand Treatment (NCT07663903) | Hangzhou Gensciences Biopharmaceutical Co., Ltd. | 2026-04-14 |
| A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain (NCT07481630) | Novo Nordisk A/S | 2026-04-13 |
| A Study to Evaluate Efficacy and Safety of HM11260C in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin (NCT07379333) | Hanmi Pharmaceutical Company Limited | 2026-04-13 |
| A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus (NCT07430306) | AstraZeneca | 2026-04-13 |
| AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight (NCT07533175) | Novo Nordisk A/S | 2026-04-13 |
| DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy (NCT07472517) | Boehringer Ingelheim | 2026-04-13 |
| An Extension of SKY-0515 in Participants With Huntington's Disease (NCT07537075) | Skyhawk Therapeutics, Inc. | 2026-04-10 |
| A Phase 3 Clinical Study of MIL62 in Systemic Lupus Erythematosus (NCT07405970) | Beijing Mabworks Biotech Co., Ltd. | 2026-04-10 |
| Efficacy and Safety of Butylphthalide in the Treatment of Multiple System Atrophy (NCT07518810) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-04-10 |
| Pancreatic Enzyme Replacement in Acute Necrotizing Pancreatitis (NCT07441824) | Asian Institute of Gastroenterology, India | 2026-04-10 |
| VAH vs VA in Newly Diagnosed Elderly AML (NCT07469046) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2026-04-10 |
| Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a Single-Center, Prospective Randomized Controlled Trial. (NCT07537998) | Pei-Rong Ding | 2026-04-10 |
| A Study of CP-COV03 Compared With Placebo in Participants With Dengue (Part 1) and Dengue-like Illness (Part 2) (NCT07576868) | Hyundai Bioscience Co., Ltd. | 2026-04-09 |
| A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034) (NCT07489495) | Merck Sharp & Dohme LLC | 2026-04-09 |
| A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma (NCT07522073) | Incyte Corporation | 2026-04-09 |
| Caffeine for Hypoxic Ischemic Encephalopathy (NCT06855108) | NICHD Global Network for Women's and Children's Health | 2026-04-08 |
| Targeting Vascular INflammation in Patients With Community-Acquired Pneumonia (NCT06710080) | Ottawa Heart Institute Research Corporation | 2026-04-08 |
| A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine (NCT07500506) | Pfizer | 2026-04-08 |
| Effect of Bismuth Add-on to Dual Therapy for Helicobacter Pylori Eradication (NCT07576959) | National Taiwan University Hospital | 2026-04-08 |
| Optimisation of High Flow Oxygen Therapy Settings During Hypoxaemic Respiratory Distress Based on Non-contact Measurement of Lung Volumes by Depth Camera (NCT06819644) | University Hospital, Brest | 2026-04-08 |
| High-Dose Dexamethasone Combined With Orelabrutinib Versus High-Dose Dexamethasone Combined With Placebo in Adult Patients With Newly Diagnosed Primary Immune Thrombocytopenia (NCT07559331) | Shandong University | 2026-04-08 |
| Phase Ⅲ Study of Efficacy and Safety of HSK39297 Tablet in Treatment of Patients With Primary IgAN (NCT07390123) | Haisco Pharmaceutical Group Co., Ltd. | 2026-04-07 |
| Efficacy of Early Argipressin in the Management of Intensive Care Patients With Norepinephrine-refractory Vasoplegic Shock (NCT07063680) | Centre Hospitalier Universitaire Dijon | 2026-04-07 |
| Evaluate the Efficacy and Safety of GZR33 Injection in Patients With Type 2 Diabetes (NCT07527078) | Gan & Lee Pharmaceuticals. | 2026-04-07 |
| A Gaucher Disease Gene Therapy Trial With FLT201 (NCT07223944) | Spur Therapeutics | 2026-04-07 |
| A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively (NCT07424404) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2026-04-07 |
| Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery (NCT06969287) | Washington University School of Medicine | 2026-04-06 |
| A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1 (NCT07455383) | Alkermes, Inc. | 2026-04-06 |
| Proteinuria in Normotensive Diabetic Patients: ARBs Alone or in Combination of SGLT2i (NCT07586371) | Dr Mudassar Saeed Pansota | 2026-04-06 |