| Safety and Preliminary Efficacy of TSHA-102 Gene Therapy in Pediatric Females Aged >2 to <4 Years With Rett Syndrome (NCT07480564) | Taysha Gene Therapies, Inc. | 2026-05-08 |
| A Clinical Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis (NCT07548840) | Taisho Pharmaceutical Co., Ltd. | 2026-05-08 |
| GAPP Induction and Concurrent Chemoradiotherapy for High-risk Locoregionally Advanced NPC. (NCT07540390) | Sun Yat-sen University | 2026-05-08 |
| A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Adult Japanese Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps (NCT07484230) | Sanofi | 2026-05-08 |
| VABu Conditioning in Elderly AML HSCT (NCT07583888) | The First Affiliated Hospital of Soochow University | 2026-05-07 |
| Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With Diabetes (NCT07428746) | Emory University | 2026-05-07 |
| Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer (NCT06197425) | Centre Hospitalier Universitaire Dijon | 2026-05-07 |
| Clinical Study of Adebrelimab Therapy in the Perioperative Treatment of Gastric Cancer or Gastroesophageal Junction Cancer (NCT07522151) | Shanghai Shengdi Pharmaceutical Co., Ltd | 2026-05-07 |
| A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism (NCT07081997) | Ascendis Pharma Bone Diseases A/S | 2026-05-07 |
| A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03) (NCT07549412) | EMD Serono Research & Development Institute, Inc. | 2026-05-06 |
| Artificial Intelligence Model-Guided Neoadjuvant Anti-HER2 Targeted Therapy (NCT07528716) | Fudan University | 2026-05-06 |
| Circulating Tumor DNA MRD-Guided Adjuvant Therapy for Curatively Resected Locally Advanced Esophageal Squamous Cell Carcinoma (NCT06914011) | Asan Medical Center | 2026-05-06 |
| Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days (NCT07614958) | A. Menarini International Licensing S.A. | 2026-05-06 |
| Prevention of RSV Infection in Infants by Administering Nirsevimab to Infants, With or Without Maternal RSV Vaccination (NCT07232706) | Centre Hospitalier Annecy Genevois | 2026-05-06 |
| A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD) (NCT05199688) | Hoffmann-La Roche | 2026-05-06 |
| AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea (NCT07571005) | Novo Nordisk A/S | 2026-05-05 |
| Long-term Safety and Tolerability of Tozorakimab in Patients With COPD and History of Exacerbations (NCT07566195) | AstraZeneca | 2026-05-05 |
| A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD) (NCT07555483) | Grifols Therapeutics LLC | 2026-05-05 |
| A Study to Evluate Efficacy and Safety of HRS-8080 Combined With Dalpiciclib in Patients With Advanced or Metastatic Breast Cancer Resistant to Adjuvant Endocrine Therapy. (NCT07354022) | Shandong Suncadia Medicine Co., Ltd. | 2026-05-05 |
| Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV) (NCT07509151) | AstraZeneca | 2026-05-05 |
| Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN (NCT07264075) | Groupe Oncologie Radiotherapie Tete et Cou | 2026-05-05 |
| Postoperative Radiotherapy With Nimotuzumab ± Benmelstobart in Intermediate-Risk Head and Neck Squamous Cell Carcinoma (NCT07535567) | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 2026-05-05 |
| A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants (NCT07573462) | Pfizer | 2026-05-04 |
| A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014) (NCT07513376) | Merck Sharp & Dohme LLC | 2026-05-04 |
| 1% Clascoterone Cream for the Treatment Acne Vulgaris (NCT07457294) | Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd. | 2026-05-04 |
| Superparamagnetic Iron Oxide for Sentinel Lymph Node Localization in Patients With Cutaneous Melanoma, a Randomized Phase III Multi-center Non- Inferiority Trial: MagMen-II (NCT07552597) | Vastra Gotaland Region | 2026-05-04 |
| The SELEQT-HF (SELEnium and CoQ10 NuTrition for Heart Failure) Study Will Evaluate the Effect of Adding Selenium/and coQ10 on Top of Standard HF Therapy in Patients With HF and Will do so Using a Pragmatic, Registry Based Randomized Controlled Trial in the Netherlands. (NCT07234422) | Netherlands Heart Institute | 2026-05-04 |
| AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01) (NCT07611110) | AstraZeneca | 2026-05-04 |
| InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression (NCT06781697) | Sunnybrook Health Sciences Centre | 2026-05-03 |
| Methotrexate Treatment in Hand Osteoarthritis Refractory to Usual Treatments (NCT07501507) | Centre Hospitalier Universitaire de Nice | 2026-05-02 |
| Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related High-grade Squamous Intraepithelial Lesions (NCT07431502) | Gustave Roussy, Cancer Campus, Grand Paris | 2026-05-01 |
| Luspatercept in Preventing Poor Erythroid Engraftment for Hematological Malignancies With Moderate to Severe Myelofibrosis (NCT07539779) | Nanfang Hospital, Southern Medical University | 2026-05-01 |
| Comparison of Rabeprazole and Vonoprazan in the Prevention of Post-endoscopic Variceal Ligation Ulcer in Patients With Cirrhosis (NCT07608536) | King George's Medical University | 2026-05-01 |
| Partner4Exercise Randomized Controlled Trial (NCT07408128) | McMaster University | 2026-05-01 |
| Tenecteplase for Late-Window Stroke Guided by DWI-FLAIR Mismatch (NCT07540416) | The First Affiliated Hospital of Zhengzhou University | 2026-05-01 |
| HSK3486 (Cipepofol) Injectable Emulsion for Induction of General Anesthesia in Pediatric Subjects Undergoing Elective Surgery (NCT07510945) | Haisco Pharmaceutical Group Co., Ltd. | 2026-05-01 |
| Lu-177 PSMA Treatment in Cell Renal Carcinoma (NCT06959433) | Ankara University | 2026-05-01 |
| IO Vancomycin Spine (NCT06748144) | The Methodist Hospital Research Institute | 2026-05-01 |
| RAIRI Model-Guided Adjuvant Therapy in Nasopharyngeal Carcinoma (NCT07590024) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-05-01 |
| Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Controlled Trial (NCT07524335) | Montreal Heart Institute | 2026-05-01 |
| Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis (NCT07435051) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-05-01 |
| Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder (NCT06943573) | Lakshmi N Yatham | 2026-05-01 |
| The Impact of Time-of-day Administration of EV/P on Objective Response Rate in Adults With Advanced Bladder Cancer (NCT07346053) | Guliz Ozgun | 2026-05-01 |
| Behavioural Intervention to Decrease Exposure to Emerging Chemical Pollutants (NCT07465315) | Universidad de Granada | 2026-05-01 |
| Adebrelimab Combined With Chemoradiotherapy in Patients With Large Bulky Stage III Unresectable Non-Small Cell Lung Cancer (NCT07560358) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-05-01 |
| Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries (NCT07573969) | Ain Shams University | 2026-05-01 |
| Biologic Augmentation of TMJ Arthroscopy Using BMAC (NCT07536399) | Weill Medical College of Cornell University | 2026-05-01 |
| A Study to Evaluate the Efficacy and Safety of MG-K10 in Participants Who Have Atopic Dermatitis (NCT07479615) | Shanghai Mabgeek Biotech.Co.Ltd | 2026-05-01 |
| Role of UC-MSC and CM to Inhibit Vision Loss in Retinitis Pigmentosa Phase I/II (NCT05909488) | PT. Prodia Stem Cell Indonesia | 2026-05-01 |
| Antenatal Magnesium Sulphate in High-Risk Preterm Patients (NCT07524972) | Cairo University | 2026-05-01 |
| Investigating the Efficacy of Tranexamic Acid as a Prophylactic Agent in Reducing Postpartum Hemorrhage Among Patients Undergoing Cesarean Section in SQUH (NCT07474077) | Sultan Qaboos University | 2026-05-01 |
| Comparison of Perioperative Immunotherapy, Adjuvant Immunotherapy or Neoadjuvant Immunotherapy for Resectable Stage II-IIIA NSCLC (NCT07554846) | Fudan University | 2026-05-01 |
| MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib (NCT07463651) | The First Affiliated Hospital of Soochow University | 2026-05-01 |
| A Study of 9MW2821 Versus Chemotherapy in Participants With Previously Treated Locally Advanced or Metastatic Triple-Negative Breast Cancer (NCT07556848) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2026-05-01 |
| Neoadjuvant SF-SBRT Plus Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC. (NCT07608159) | Shanghai Pulmonary Hospital, Shanghai, China | 2026-05-01 |
| A Study of Adjuvant NDV-01 (Sustained-release Gemcitabine-docetaxel) for the Treatment of Intermediate Risk NMIBC Following TURBT (NCT07313891) | Relmada Therapeutics, Inc. | 2026-05-01 |
| Effects of VALsartan On atRIAl Mitral Regurgitation (NCT07539298) | Jonathan Beaudoin | 2026-05-01 |
| Comparison of Ferrous Salt vs. Liposomal Iron in Adult Women With Iron-Deficiency Anemia (NCT07556731) | Hospital General de Mexico | 2026-05-01 |
| A Novel Extracorporeal Liver Support Therapy In ALCF and to Evaluate the Efficacy of DIALIVE 2.0, a Liver Dialysis Device. (NCT07347275) | Yaqrit Ltd | 2026-05-01 |
| QLC7401 in Participants With Heterozygous Familial Hypercholesterolemia (HeFH) (NCT07450378) | Qilu Pharmaceutical Co., Ltd. | 2026-05-01 |
| Jianpi Lishi Jiedu Granules for Prevention of Postoperative Recurrence in Colorectal Advanced Adenomas (NCT07505056) | Nanjing First Hospital, Nanjing Medical University | 2026-05-01 |
| Protective Efficacy , Immunogenicity and Safety of the Tetravalent Inactivated Enterovirus Vaccine (Vero Cell). (NCT07611513) | Sinovac Biotech Co., Ltd | 2026-05-01 |
| Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases (NCT07321847) | Immunophotonics, Inc. | 2026-05-01 |
| Safety and Efficacy of Remote Ischemic Conditioning in Patients With Acute Myocardial Injury Following Acute Ischemic Stroke (NCT07531394) | Capital Medical University | 2026-05-01 |
| MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES) (NCT07538284) | Sixth Affiliated Hospital, Sun Yat-sen University | 2026-05-01 |
| PRECISE Phenotyping to Guide Therapies for Coronary Microvascular Dysfunction (NCT07533747) | King's College London | 2026-05-01 |
| "Dapagliflozin vs Dapagliflozin-Finerenone for Albuminuria in CKD With Type 2 Diabetes" (NCT07598864) | Chittagong Medical College | 2026-05-01 |
| Clinical Trial of PCV13 in Infants Aged Approximately 2 Months (42 to 89 Days) (NCT07593924) | Sinovac Life Sciences Co., Ltd. | 2026-05-01 |
| Confirmatory Study of Govorestat in CMT-SORD (NCT07191912) | Applied Therapeutics, Inc. | 2026-05-01 |
| Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department (NCT06315920) | Oman Medical Speciality Board | 2026-05-01 |
| Phosphate-Containing Replacement Fluid for Patients Undergoing CRRT (NCT07550894) | Sun Yat-sen University | 2026-05-01 |
| Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery (NCT07539623) | Icahn School of Medicine at Mount Sinai | 2026-05-01 |
| The Comparison Between DEDTI BR and T/E BR (NCT07593846) | West China Hospital | 2026-05-01 |
| Stratification and Treatment in Early Psychosis Study - PROMOTE (NCT07434973) | University of Oxford | 2026-05-01 |
| Tiaoshen Anti-cancer Protocol and CBT for Insomnia and Survival in Ovarian Cancer (NCT07550205) | Shanghai Municipal Hospital of Traditional Chinese Medicine | 2026-05-01 |
| Clinical Study of DA-001 as a Treatment for Hair Shedding Reduction and Hair Re-Growth (NCT06648850) | Applied Biology, Inc. | 2026-05-01 |
| To Evaluate the Efficacy, Safety, and Tolerability of Dronabinol Oral Solution for Agitation in Patients With Alzheimer's Disease (NCT07422311) | Benuvia Therapeutics Inc. | 2026-05-01 |
| Anti-CD25 Monoclonal Antibody for Prevention of Acute GVHD After Haploidentical HSCT (NCT07689630) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2026-05-01 |
| SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer (NCT07551479) | Fudan University | 2026-05-01 |
| Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease (NCT07017634) | CGBio Inc. | 2026-05-01 |
| Intranasal Insulin to Prevent Intensive Care Unit Delirium (NCT07532577) | Radboud University Medical Center | 2026-04-30 |
| Autologous Whole Blood Therapy in Chronic Idiopathic Urticaria Patients. (NCT07486583) | Cairo University | 2026-04-30 |
| A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder (NCT07573176) | Janssen Research & Development, LLC | 2026-04-30 |
| Donanemab (LY3002813) Trial in Chinese Participants With Cognitively Unimpaired (Preclinical) Alzheimer's Disease (NCT07571161) | Eli Lilly and Company | 2026-04-30 |
| A Study Of SHR-1918 In Participants With Hypercholesterolemia With Inadequate Lipid Control on Statins Plus PCSK9 Inhibitors (NCT07404553) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2026-04-30 |
| A Pivotal Clinical Trial of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Injection (HiCM-188) for the Treatment of Advanced Heart Failure(NYHA III-IV) (NCT07496372) | HELP Therapeutics Co., Ltd. | 2026-04-30 |
| Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL (NCT07321652) | Alliance for Clinical Trials in Oncology | 2026-04-30 |
| A Clinical Trial Evaluating the Efficacy and Safety of Sanhuang Jingshiming Pills in the Treatment of nAMD (NCT07269769) | Tasly Pharmaceutical Group Co., Ltd | 2026-04-30 |
| A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma (NCT07490301) | AbbVie | 2026-04-30 |
| A Study of the Effectiveness and Safety of JS1-1-01 Tablet in Patients With Moderate to Severe Depression (NCT07485595) | Tasly Pharmaceutical Group Co., Ltd | 2026-04-30 |
| VAG Versus Standard Chemotherapy With FLT3 Inhibitor in Adult Patients With FLT3-Mutated AML (NCT07407140) | Institute of Hematology & Blood Diseases Hospital, China | 2026-04-30 |
| Traditional Chinese Medicine for the Prevention of Radiotherapy-Induced Oral Mucositis (RTOM) (NCT07543978) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2026-04-30 |
| Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma (NCT07000253) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2026-04-29 |
| PREcision MEDicine In Achalasia (PREMEDIA) (NCT07293650) | Northwestern University | 2026-04-29 |
| Azacitidine + Venetoclax VS Azacitidineas Maintenance Therapy in AML (NCT07539818) | Institute of Hematology & Blood Diseases Hospital, China | 2026-04-29 |
| Adaptive Platform Trial of Treatments for Respiratory Infections in Community Settings (TreatResp) (NCT07314905) | Unity Health Toronto | 2026-04-29 |
| Open-Label Safety Study of AXS-14 in Subjects With Fibromyalgia (NCT07637162) | Axsome Therapeutics, Inc. | 2026-04-29 |
| Precision Radiotherapy for Refractory Brain Metastases: A Multicenter Study (NCT07586657) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-04-28 |
| Proton Versus Photon Therapy in Head and Neck Squamous Cell Carcinomas. (NCT07580300) | Oslo University Hospital | 2026-04-28 |
| COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular Comorbidities (NCT07245680) | Assistance Publique - Hôpitaux de Paris | 2026-04-28 |