| Design and Rationale of the COLT Study (NCT07432529) | Azienda Sanitaria Locale ASL 6, Livorno | 2026-06-01 |
| Comparative Analysis of Immunological Responses to Vitamin D Replacement Therapy in Black and West African Men Diagnosed With Prostate Cancer: Elucidating Differential Effects on Immune Function Between Patients With Localized Disease and Those With Metastatic Progression (NCT07598032) | University of Ilorin Teaching Hospital | 2026-06-01 |
| A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (NCT07518186) | Janssen Research & Development, LLC | 2026-05-31 |
| A Study Evaluating Aprocitentan Tablets(SYH9108) for the Treatment of Resistant Hypertension (NCT07635914) | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 2026-05-31 |
| A Phase III Clinical Trial to Evaluate the Efficacy and Safety of Octreotide Long-acting Injection in Patients With Acromegaly (NCT07623824) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2026-05-31 |
| Phase III Clinical Trial of Changji'an Capsules in the Treatment of Irritable Bowel Syndrome With Predominant Diarrhea (Liver-Qi Invading Spleen Syndrome) (NCT07610434) | Beijing Hospital of Traditional Chinese Medicine | 2026-05-31 |
| Colchicine for the Reduction of Dependency and Vascular Events After an Acute Intracerebral Hemorrhage (NCT06587737) | Population Health Research Institute | 2026-05-30 |
| A Study to Evaluate the Safety, Efficacy, and PK of ONO-2017 in Japanese Patients With POS 2 to 17 Year Olds (NCT07594158) | Ono Pharmaceutical Co., Ltd. | 2026-05-30 |
| A Prospective, Multicenter, Randomized, Parallel-controlled, Superiority Trial (NCT07534995) | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine | 2026-05-30 |
| ATRA for Management of Primary ITP (NCT07597395) | Peking University People's Hospital | 2026-05-30 |
| Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS) (NCT07468448) | Population Health Research Institute | 2026-05-30 |
| Local Consolidation After Sintilimab Plus Lenvatinib for Metastatic Liver Cancer (NCT07537946) | Tongji Hospital | 2026-05-30 |
| Chidamide for Maintenance Treatment of HBV-infected Diffuse DLBCL in Patients Initially Treated With R-CHOP (NCT07493109) | Ou Bai, MD/PHD | 2026-05-30 |
| Fixed-dose Combination of Etoricoxib + Cyclobenzaprine for Pain Relief After Third Molar Extraction in Brazil (NCT05683574) | Eurofarma Laboratorios S.A. | 2026-05-30 |
| A Study to Learn About How a New Pneumococcal Vaccine Works in Infants. (NCT07629440) | Pfizer | 2026-05-29 |
| Phase III Study of HRS-7535 for Hypertension With Overweight or Obesity (NCT07528027) | Shandong Suncadia Medicine Co., Ltd. | 2026-05-29 |
| A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence (NCT07598708) | Centessa Pharmaceuticals (UK) Limited | 2026-05-29 |
| Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer (NCT07480356) | Protara Therapeutics | 2026-05-29 |
| A Phase III Study To Evaluate the Efficacy And Safety Of HRS9531 In Participants With Atherosclerotic Cardiovascular Disease (NCT07551492) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2026-05-29 |
| A Phase 3 Study of Extended-release Tacrolimus in Subjects With Pulmonary Arterial Hypertension and Functional Limitations (NCT07612657) | VIVUS LLC | 2026-05-29 |
| A Study of HS-10506 in Chinese Patients With Insomnia Disorder (NCT07587385) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2026-05-29 |
| A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle (NCT06915233) | Vericel Corporation | 2026-05-28 |
| Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research (NCT07623668) | Oculis | 2026-05-28 |
| A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer (NCT07459751) | Shanghai Henlius Biotech | 2026-05-27 |
| A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration (NCT07614776) | Amgen | 2026-05-27 |
| A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis (NCT07463521) | UCB Biopharma SRL | 2026-05-27 |
| Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial (NCT07567040) | Ohio State University | 2026-05-27 |
| Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia (NCT07022678) | Children's Oncology Group | 2026-05-26 |
| An Efficacy, Safety, and Immunogenicity Study of CHIKV VLP Vaccine for the Prevention of Chikungunya Disease in Adolescents and Adults (NCT07467707) | Bavarian Nordic | 2026-05-26 |
| Efficacy of the Use of Neoadjuvant With/Without Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Colon Cancer (NCT06783491) | Maimónides Biomedical Research Institute of Córdoba | 2026-05-26 |
| Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment (NCT07444567) | AstraZeneca | 2026-05-25 |
| INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV) (NCT07429266) | Ono Pharmaceutical Co., Ltd. | 2026-05-25 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase III Study of HSK39004 Inhalation Powder for the Treatment of COPD (NCT07583849) | Haisco Pharmaceutical Group Co., Ltd. | 2026-05-24 |
| A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis (NCT07577856) | Janssen Research & Development, LLC | 2026-05-23 |
| Study on the Effect of Oral Diammonium Glycyrrhizinate in Attenuating Toxicity and Enhancing Efficacy of CAR-T Cell Therapy (NCT07616271) | Tongji Hospital | 2026-05-22 |
| BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease (NCT07492641) | BeOne Medicines | 2026-05-22 |
| Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy (NCT07479797) | Kite, A Gilead Company | 2026-05-22 |
| PROlonged Corticosteroid Treatment or N-ACetylcysteine for Severe Alcoholic Hepatitis (NCT06956482) | University Hospital, Lille | 2026-05-22 |
| A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer (NCT07525206) | AbbVie | 2026-05-22 |
| A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease (NCT07577843) | Janssen Research & Development, LLC | 2026-05-22 |
| A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). (NCT07602582) | Eli Lilly and Company | 2026-05-22 |
| Radiotherapy With GX Regimen as Adjuvant Therapy for High-risk Patients Following Pancreatic Cancer Surgery (NCT07632118) | Tianjin Medical University Cancer Institute and Hospital | 2026-05-22 |
| Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 ) (NCT07621718) | Revolution Medicines, Inc. | 2026-05-22 |
| A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM) (NCT07393282) | Regeneron Pharmaceuticals | 2026-05-21 |
| A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions (NCT07422480) | Takeda | 2026-05-21 |
| Safety, Tolerability, Pharmacokinetics, and Efficacy of Filgotinib for the Treatment of Polyarticular-course Juvenile Idiopathic Arthritis in Children and Adolescents (NCT07554495) | Alfasigma S.p.A. | 2026-05-21 |
| A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight (NCT07564414) | Novo Nordisk A/S | 2026-05-21 |
| SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC (NCT07549399) | Sixth Affiliated Hospital, Sun Yat-sen University | 2026-05-20 |
| Selective Mediastinal Lymph Node Sampling Versus Systematic medIastinal Lymph Node Dissection After Neoadjuvant Chemoimmunotherapy for Non-small Cell Lung Cancer (SCIENCE Study) (NCT07617389) | Wen-zhao ZHONG | 2026-05-20 |
| A Phase III Study of SYHA1813 for Recurrent or Progressive High-Grade Meningiomas (NCT07613450) | Shanghai Runshi Pharmaceutical Technology Co., Ltd | 2026-05-20 |
| Study of Becotatug Vedotin Added to Standard Treatment for Advanced Bile Duct Cancer With EGFR Mutations (NCT07598318) | Sir Run Run Shaw Hospital | 2026-05-20 |
| Use of Steroid Injections to Prevent the Recurrence of Tracheal Stenosis in Idiopathic Subglottic Stenosis (NCT07228104) | Johns Hopkins University | 2026-05-20 |
| AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight (NCT07400107) | Novo Nordisk A/S | 2026-05-20 |
| Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency (NCT06948214) | Lumos Pharma | 2026-05-20 |
| A Clinical Study of Liposomal Irinotecan for Second-Line Therapy in Metastatic Colorectal Cancer (NCT07585279) | Hebei Medical University Fourth Hospital | 2026-05-20 |
| Remote Ischemic Conditioning for High Altitude Polycythemia in High-Altitude Immigrant Populations (NCT07562464) | Capital Medical University | 2026-05-20 |
| Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP) (NCT07594301) | Xiang Luo | 2026-05-19 |
| A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar (NCT07284511) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2026-05-19 |
| Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis (NCT07356284) | ProMedica Health System | 2026-05-19 |
| Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea (NCT07332442) | Yale University | 2026-05-18 |
| A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005) (NCT07570173) | Merck Sharp & Dohme LLC | 2026-05-18 |
| Study of the Efficacy and Safety of Goflikicept and Olokizumab as the Second-line Therapy in Patients With Still's Disease (NCT07625384) | R-Pharm International, LLC | 2026-05-18 |
| Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults at High Risk of Delayed Graft Function (DGF) Following Kidney Allograft Transplantation (NCT07020832) | Apellis Pharmaceuticals, Inc. | 2026-05-18 |
| MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder (NCT07118839) | VA Office of Research and Development | 2026-05-18 |
| Sac-TMT Sequential Capecitabine Versus Capecitabine in Early-Stage High-Risk Triple-Negative Breast Cancer Without BRCA Mutations (NCT07628504) | Fudan University | 2026-05-18 |
| Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients (NCT06807021) | Birch BioMed Inc | 2026-05-15 |
| Ultrasound Guided Erectror Spinae Block Versus Intracavitary During Medical Thoracoscopy (NCT07572019) | Kafrelsheikh University | 2026-05-15 |
| Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Cessation in Adults Using Nicotine-Containing E Cigarettes (NCT07392125) | Achieve Life Sciences | 2026-05-15 |
| Boostability Assessment of Three Rabies Pre-Exposure Regimens in Healthy Volunteers 5 Years Following Priming. (NCT07455318) | Institute of Tropical Medicine, Belgium | 2026-05-15 |
| A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A (NCT07416526) | Hoffmann-La Roche | 2026-05-15 |
| HAIC vs. TACE Combined With Sintilimab and Bevacizumab for Intermediate HCC (Beyond Up-To-Seven) (NCT07594340) | Binkui Li | 2026-05-15 |
| A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in Patients With Claudin (CLDN)18.2-Positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GC/GEJC) Who Have Received Prior First-Line Treatment (NCT07518147) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-05-15 |
| ANKTIVA Plus BCG Versus BCG Monotherapy In Participants With BCG-Naïve/BCG-Exposed High-Grade Non-Muscle Invasive Papillary Bladder Cancer (NCT07551544) | ImmunityBio, Inc. | 2026-05-15 |
| A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer (NCT07113275) | Tao Zhang | 2026-05-15 |
| IS-001 Injection in Patients Undergoing Robotic-Assisted Colorectal Surgery (NCT07346066) | Intuitive Surgical | 2026-05-14 |
| Levetiracetam for Seizure Prevention After Brain Tumor Surgery (NCT07239115) | Beijing Tiantan Hospital | 2026-05-14 |
| Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1 (NCT07486934) | Dyne Therapeutics | 2026-05-14 |
| Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer (NCT07392892) | Pfizer | 2026-05-14 |
| Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive Ventilation (NCT07530146) | Helwan University | 2026-05-13 |
| A Study of VRT106, Combined With Camrelizumab, and Apatinib for Advanced HCC (NCT07589244) | Guangzhou Virotech Pharmaceutical Co., Ltd. | 2026-05-13 |
| Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations (NCT06998940) | SWOG Cancer Research Network | 2026-05-13 |
| A Clinical Study of TS-172 in Hyperphosphatemia Patients on Peritoneal Dialysis (NCT07548853) | Taisho Pharmaceutical Co., Ltd. | 2026-05-13 |
| Comparison of Early Pleural Irrigation Strategy With Saline to the Standard of Care for the Management of Complicated Pleural Infections. (NCT07666464) | Centre Hospitalier Universitaire, Amiens | 2026-05-13 |
| A Phase Ⅱ/Ⅲ Clinical Trial of RC148 Plus Chemotherapy as 1L Therapy for Unresectable or Metastatic Colorectal Cancer (NCT07462143) | RemeGen Co., Ltd. | 2026-05-12 |
| Phase III Clinical Study of VC005 in Adult and Adolescents With Mild to Moderate Atopic Dermatitis (NCT07592585) | Jiangsu vcare pharmaceutical technology co., LTD | 2026-05-12 |
| A Study to Learn Safety and Immune Response to Study Vaccine -RSVpreF in Adults at High Risk of Severe RSV Disease. (NCT07543380) | Pfizer | 2026-05-11 |
| Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Analgesia in Abdominal Surgery (NCT07709598) | Shanghai Huilun Pharmaceutical Co., Ltd. | 2026-05-11 |
| To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis. (NCT07605338) | Colgate Palmolive | 2026-05-11 |
| A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity (NCT07567001) | Novo Nordisk A/S | 2026-05-11 |
| A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer (NCT07265674) | J-Pharma Co., Ltd. | 2026-05-11 |
| Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH) (NCT07575399) | Amgen | 2026-05-11 |
| Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309) (NCT07566156) | Astellas Pharma Global Development, Inc. | 2026-05-11 |
| Efficacy and Safety of NB003 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) (NCT07379047) | Ningbo Newbay Technology Development Co., Ltd | 2026-05-11 |
| An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) (NCT07517263) | Novartis Pharmaceuticals | 2026-05-11 |
| Efficacy of Remote Ischemic Conditioning for Hypertension in High-Altitude Immigrant Populations (NCT07562477) | Capital Medical University | 2026-05-10 |
| Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample: a Study Protocol of a Randomized Clinical Trial (NCT07574658) | University of Sao Paulo | 2026-05-10 |
| A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend) (NCT07592689) | Definium Therapeutics US, Inc. | 2026-05-10 |
| Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Analgesia in Orthopedic Surgery (NCT07699601) | Shanghai Huilun Pharmaceutical Co., Ltd. | 2026-05-09 |
| SCTB41 Combined With Chemotherapy in Advanced Squamous Non-Small Cell Lung Cancer (NCT07662395) | Sinocelltech Ltd. | 2026-05-09 |
| Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TB (NCT06568484) | Johns Hopkins University | 2026-05-08 |