| Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome (NCT07238465) | University of Colorado, Denver | 2026-04-06 |
| Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers (NCT07560150) | Amphastar Pharmaceuticals, Inc. | 2026-04-06 |
| Bacteriophage Therapy for Orthopedic Implant-Associated Infections (NCT07533292) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-04-05 |
| Evaluating the Efficacy and Safety of of HSK44459 in People With Progressive Pulmonary Fibrosis (NCT07503587) | Haisco Pharmaceutical Group Co., Ltd. | 2026-04-05 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of HSK44459 Tablets in Patients With Idiopathic Pulmonary Fibrosis (NCT07519070) | Haisco Pharmaceutical Group Co., Ltd. | 2026-04-05 |
| Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable (NCT07430956) | Regeneron Pharmaceuticals | 2026-04-03 |
| RC148 Plus Platinum-Based Chemotherapy vs Tislelizumab Plus Platinum-Based Chemotherapy for First-Line Squamous Non-Small Cell Lung Cancer (sqNSCLC) (NCT07416474) | RemeGen Co., Ltd. | 2026-04-03 |
| A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With Risdiplam (NCT07444476) | Biogen | 2026-04-03 |
| Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to Standard of Care for Maintenance Treatment of Participants With Recurrent Platinum-sensitive Ovarian Cancer After Second-line (2L) Platinum-based Doublet Chemotherapy (NCT07225270) | Genmab | 2026-04-03 |
| Phase IIb and III Safety and Efficacy Study Chlorin E6 Gel Photodynamic Therapy for Diabetic Foot Ulcers: (NCT07488247) | United Medical and Dental College | 2026-04-02 |
| An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1) (NCT07456696) | Transcend Therapeutics | 2026-04-02 |
| Efficacy and Safety of Minocycline in Acute Spontaneous Intracerebral Hemorrhage (NCT07338175) | Beijing Tiantan Hospital | 2026-04-02 |
| Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE) (NCT07428499) | ADARx Pharmaceuticals, Inc. | 2026-04-02 |
| Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children (NCT07145645) | University of Calgary | 2026-04-02 |
| A Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (NCT07540221) | Grifols Therapeutics LLC | 2026-04-02 |
| A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2) (NCT07355218) | EMD Serono Research & Development Institute, Inc. | 2026-04-01 |
| A Study of SHR-1918 In Participants With Hypertriglyceridemia (NCT07349615) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2026-04-01 |
| International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020) (NCT07476729) | Charite University, Berlin, Germany | 2026-04-01 |
| Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement (NCT07090343) | Leiden University Medical Center | 2026-04-01 |
| Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial (NCT07454707) | Sunnybrook Health Sciences Centre | 2026-04-01 |
| Unknown Time of Onset Stroke RePerfusIon Without Advanced Imaging (NCT07475949) | First Affiliated Hospital of Guangxi Medical University | 2026-04-01 |
| A Phase III Study of First-line Anlotinib Combined With Benmelstobart in Patients With Advanced Esophageal Squamous Cell Carcinoma (NCT07446335) | The First Affiliated Hospital of Zhengzhou University | 2026-04-01 |
| A Phase III Study of SYS6010 Versus Chemotherapy in HER2-Negative, EGFR-Positive Recurrent or Metastatic Breast Cancer (NCT07406542) | CSPC Megalith Biopharmaceutical Co.,Ltd. | 2026-04-01 |
| Enarodustat + CsA vs CsA in Newly Diagnosed TD-NSAA (NCT07548671) | Peking Union Medical College Hospital | 2026-04-01 |
| TGRX-678 Chinese Phase III in Chronic Myelogenous Leukemia (CML) Patients (NCT07489755) | Shenzhen TargetRx Co., Ltd. | 2026-04-01 |
| A Phase 3, Double-blind/Double-dummy, Safety/Efficacy/Superiority of Sibutramine/Topiramate XR in Adults With Overweight (NCT05209984) | Eurofarma Laboratorios S.A. | 2026-04-01 |
| Feasibility of the Application of a New Six-month Treatment for Multidrug-resistant Tuberculosis (MDR-TB) Patients in France (FAST-MDR) (NCT07486024) | Assistance Publique - Hôpitaux de Paris | 2026-04-01 |
| PCSK9 Inhibitors in the Treatment of Calcific Aortic Stenosis (NCT07256197) | Beijing Anzhen Hospital | 2026-04-01 |
| Stop Air Leak by Talc or Autologous Blood Patch Therapy (NCT06883188) | Chinese University of Hong Kong | 2026-04-01 |
| Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral Neuropathy (NCT06715462) | Eurofarma Laboratorios S.A. | 2026-04-01 |
| Selenium Intervention Registry Randomized Trial in Heart Failure (NCT07543562) | Skane University Hospital | 2026-04-01 |
| A Study Comparing the MAGICTouch™ Sirolimus-coated Balloon With a Paclitaxel-coated Balloon for Treating Severe Narrowing or Blockage in the Femoropopliteal Arteries. (NCT07359807) | Concept Medical Inc. | 2026-04-01 |
| Cetuximab Combined With Pembrolizumab or Finotonlimab and Chemotherapy in R/M HNSCC (NCT07509099) | Ji Dongmei | 2026-04-01 |
| Octreotide Microspheres for Preventing Pancreatic Fistula (NCT07479784) | Shanghai Zhongshan Hospital | 2026-04-01 |
| Phase III Clinical Trial of Hepalatide in Patients With Chronic Hepatitis D (NCT07309380) | Shanghai HEP Pharmaceutical Co., Ltd. | 2026-04-01 |
| A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies (NCT07554807) | First Affiliated Hospital of Zhejiang University | 2026-04-01 |
| Intra-Arterial Tirofiban After Complete Recanalization for Acute Intracranial Large-Vessel Occlusion (NCT07537933) | Shandong Provincial Hospital | 2026-04-01 |
| Topical Chlorhexidine Spray for the Prevention of Acute Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma: (NCT07559877) | Jiangxi Provincial Cancer Hospital | 2026-04-01 |
| Safety and Efficacy of a Phased Transition From Epogen to Three Times Weekly Oral Vadadustat for the Treatment of Anemia in Subjects Receiving In-Center Hemodialysis (NCT07565701) | Geoff Block | 2026-04-01 |
| Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major Depressive Disorder (NCT07703722) | Khyber Medical University Peshawar | 2026-04-01 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of RSS0393 Ointment in Adult Patients With Plaque Psoriasis. (NCT07543224) | Reistone Biopharma Company Limited | 2026-04-01 |
| A Controlled Study to Evaluate the Efficacy of Allogeneic MesenCure for the Treatment of Patients With ARDS (NCT05497401) | BonusBio Group Ltd | 2026-04-01 |
| Effect of Aspirin and Folic Acid for Sudden Sensorineural Hearing Loss (NCT07113158) | Assistance Publique - Hôpitaux de Paris | 2026-04-01 |
| Study of Cannabidiol in Sanfilippo Syndrome (NCT06333041) | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 2026-04-01 |
| Reducing Chronic Pain After Lung Surgery: A Trial of Limiting NSAIDs During Recovery (NCT07108582) | University Hospital, Strasbourg, France | 2026-04-01 |
| Efficacy of a Toothpaste in Reducing Plaque, Gingivitis, and Gingival Bleeding (NCT07499115) | Colgate Palmolive | 2026-04-01 |
| Pembrolizumab Adjuvant in Patients With Early-stage Triple Negative Breast Cancer With Residual Disease After Neoadjuvant Pembrolizumab Plus Chemotherapy (NCT07486687) | The Netherlands Cancer Institute | 2026-04-01 |
| Stroke Minimization Through Additive Anti-atherosclerotic Agents in Routine Treatment II Study (SMAART II) (NCT05963568) | Northern California Institute of Research and Education | 2026-04-01 |
| A Phase 2/3 Study on the Efficacy and Safety of Mangaciclanol for Contrast-Enhanced MRI of CNS or Body in Adult Patients (NCT07472491) | GE Healthcare | 2026-04-01 |
| DEC3-VEN vs. Venetoclax-Based vs. DA Regimens in Newly Diagnosed AML (NCT07712848) | The Second Affiliated Hospital of Kunming Medical University | 2026-04-01 |
| Androgenic Alopecia TH07 Clinical Trial (NCT07435012) | Triple Hair Inc | 2026-04-01 |
| Study to Evaluate Efficacy and Safety of Gyntima® Balance in Preventing Recurrences of Bacterial Vaginosis (NCT07527572) | Kaneka Americas Holding Inc. | 2026-04-01 |
| VEN+IDAC vs IDAC in AML (NCT07537257) | Guangdong Second Provincial General Hospital | 2026-04-01 |
| Comparison of Topical Photodynamic Therapy With Topical Calcipotriol in Management of Oral Leukoplakia (NCT07453472) | Dr. Shalini Gupta | 2026-04-01 |
| Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls. (NCT06692712) | Elpida Therapeutics SPC | 2026-04-01 |
| Normal Saline Infusion After Intravenous Thrombolysis in Stroke (NCT07497542) | Tianjin Medical University General Hospital | 2026-04-01 |
| The Impact of Time-of-day-Dependent Administration of Nivolumab-Ipilimumab (ICI/ICI) Combination on Overall Survival in Adults With Advanced Kidney Cancer: A Pragmatic Multicenter, Randomized Controlled Trial. (NCT07338981) | Guliz Ozgun | 2026-04-01 |
| Comparison of Two Etoposide Initiation Strategies for Severe Hemophagocytic Lymphohistiocytosis (NCT07497438) | Assistance Publique - Hôpitaux de Paris | 2026-04-01 |
| Megestrol Acetate for First-Line Treatment of Malnourished Non-Small Cell Lung Cancer (NCT07477808) | Hunan Province Tumor Hospital | 2026-04-01 |
| Becotatug Vedotin (MRG003) With PD-1 Blockade and Chemoradiotherapy in High-Risk Locoregionally Advanced Nasopharyngeal Carcinoma (NCT07524413) | Sun Yat-sen University | 2026-04-01 |
| IBI306 Monotherapy in Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia (NCT07473960) | Innovent Biologics (Suzhou) Co. Ltd. | 2026-04-01 |
| Cryoablation Versus Lumpectomy in Early-Stage Breast Cancer (NCT07483996) | Franciscus Gasthuis & Vlietland (Hospital) | 2026-04-01 |
| To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless (NCT07266974) | Jaweria Gul Keyani | 2026-04-01 |
| DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. (NCT07440290) | Cancer Research UK | 2026-04-01 |
| Chiauranib Plus PD-1 Inhibitor, Albumin-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (NCT07445295) | Chipscreen Biosciences, Ltd. | 2026-03-31 |
| Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas (NCT07407803) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2026-03-31 |
| Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung (NCT07499674) | Vergent Bioscience, Inc. | 2026-03-31 |
| A Study to Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia on a Background of Lipid-lowering Therapy (NCT07421284) | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 2026-03-31 |
| A Phase III Study of HS-20093 Injection Combined With Adebrelimab Versus Docetaxel in Previously Treated Patients With Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Without Actionable Genomic Alterations (NCT07464327) | Hansoh BioMedical R&D Company | 2026-03-31 |
| Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma (NCT07152821) | Canadian Cancer Trials Group | 2026-03-31 |
| A Study Comparing C Pola R-CHP+X With CR-CHOP in the Treatment of Previously Untreated DEL Under the Guidance of Genotyping (NCT07511114) | Ruijin Hospital | 2026-03-31 |
| Neuronavigation-assisted Stereotactic Minimally Invasive Puncture With Tenecteplase for Acute Lobar Intracerebral Hemorrhage (NCT07471256) | Beijing Tiantan Hospital | 2026-03-31 |
| Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial (NCT07200830) | Alliance for Clinical Trials in Oncology | 2026-03-31 |
| A Study of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Post-COVID Condition (NCT07184385) | StemCyte, Inc. | 2026-03-31 |
| CDK4/6 Inhibitors Intensification for Chemotherapy Omission in Small Size High-risk ER-positive Breast Cancer（Cinnamon） (NCT07432178) | Fudan University | 2026-03-31 |
| A Study of AK104 (SC) in Combination With Oxaliplatin and Capecitabine (XELOX) Versus AK104 (IV) in Combination With XELOX in Participants With Unresectable Locally Advanced or Metastatic Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma (NCT07449780) | Akeso | 2026-03-31 |
| A Study to Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) (NCT07465263) | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 2026-03-31 |
| Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome (NCT06405178) | Beni-Suef University | 2026-03-30 |
| A Study of SHR-A2102 Versus Investigator's Choice of Chemotherapy in Patients With Platinum-based Chemotherapy and PD-(L)1 Inhibitor Treatment Failed Recurrent or Metastatic Cervical Cancer (NCT07418749) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-03-30 |
| Trial of a Virtual Exercise-based Rehabilitation Program to Treat Persistent Chemotherapy-Induced Peripheral Neuropathy (CIPN) (NCT07481149) | University Health Network, Toronto | 2026-03-30 |
| A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients (NCT07549321) | Renaissance Pharma Ltd. | 2026-03-30 |
| Intra-Sinus Povidone-Iodine and Budesonide After Endoscopic Sinus Surgery for Chronic Rhinosinusitis (NCT07383402) | Amin Javer | 2026-03-30 |
| Clinical Trial to Evaluate the Efficacy and Safety of the Aurora® Digital Medical Device in Adult Patients With Moderate to Severe Generalized Anxiety Disorder (NCT07477990) | Psicofarma, S.A. De C.V. | 2026-03-29 |
| Golidocitinib Versus Placebo as Maintenance Therapy for Peripheral T-Cell Lymphoma (NCT07300514) | Fudan University | 2026-03-27 |
| Hypofractionated vs Conventional RT After Prosthetic Breast Reconstruction (NCT07084519) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-03-27 |
| Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex (NCT07326540) | BioVersys SAS | 2026-03-27 |
| A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) (NCT07440225) | EyeBiotech Ltd. | 2026-03-27 |
| A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use (NCT07446439) | Vanda Pharmaceuticals | 2026-03-27 |
| A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment. (NCT07490262) | Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. | 2026-03-27 |
| A Study of Methylprednisolone in People Having Liver Surgery (NCT07507643) | Memorial Sloan Kettering Cancer Center | 2026-03-27 |
| A Study of HDM1005 in Participants With T2DM Not Controlled With Metformin Alone or in Combination With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor (NCT07417306) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2026-03-27 |
| Effect of Tributyrin Supplementation on Glycemic Control, Inflammation, and Cardiovascular Risk in Patients With Type 2 Diabetes (NCT07503548) | Ain Shams University | 2026-03-26 |
| Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial (NCT07424846) | University of Washington | 2026-03-26 |
| The Effect of Lactoferrin on Pain Management Following Cesarean Section (NCT07502235) | Ain Shams University | 2026-03-26 |
| The Effect of Adjunctive Melatonin With Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial Infections (NCT07503600) | Ain Shams University | 2026-03-26 |
| Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial (NCT07413055) | Oman Ministry of Health | 2026-03-25 |
| Phase 3 Study to Assess Safety and Efficacy of 177Lu-TLX250 in Advanced Relapsed or Recurrent ccRCC (NCT07197580) | Telix Pharmaceuticals (Innovations) Pty Limited | 2026-03-25 |
| Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia (NCT07363577) | LB Pharmaceuticals Inc. | 2026-03-25 |
| Efficacy and Safety of Intra-arterial Tenecteplase in Acute Ischemic Stroke Patients With Medium Vessel Occlusion Stroke (DATE-MeVO) (NCT07469293) | Southwest Hospital, China | 2026-03-25 |
| A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5) (NCT06947941) | Bristol-Myers Squibb | 2026-03-25 |