| Clinical Trial of Anusol Ointment for Symptom Relief in Patients With Haemorrhoids (NCT05157711) | Church & Dwight Company, Inc. | 2021-11-25 |
| Palliative UNConventional Hypofractionation Trial for Metastatic Bone Disease (NCT05115331) | University of Cincinnati | 2021-11-24 |
| The Efficacy and Safety of Cobitolimod in Participants With Moderate to Severe Active Left-Sided Ulcerative Colitis (NCT04985968) | InDex Pharmaceuticals | 2021-11-24 |
| Entospletinib Plus Intensive Induction/Consolidation Chemotherapy in Newly Diagnosed NPM1-mutated AML (NCT05020665) | Kronos Bio | 2021-11-24 |
| VIRTUOSE : Efficiency of Sildenafil on the Absolute Claudication Distance of Peripheral Arterial Disease Patients With Intermittent Claudication. (NCT03686306) | Rennes University Hospital | 2021-11-24 |
| Evaluate the Safety and Efficacy of Nirsevimab in Healthy Preterm and Term Infants in China (NCT05110261) | AstraZeneca | 2021-11-24 |
| A Trial of Dexmedetomidine Hydrochloride Nasal Spray in Preoperative Sedation of Children (NCT05111431) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2021-11-24 |
| A Study to Compare Sitavig (Acyclovir) Buccal Tablet With a Placebo in the Treatment of Herpes Labialis in Participants Whose Immune System Works Normally (NCT05098938) | Bayer | 2021-11-23 |
| Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II (NCT05001555) | Laboratorios Silanes S.A. de C.V. | 2021-11-23 |
| Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease (NCT05030428) | Novartis Pharmaceuticals | 2021-11-23 |
| Dapsone Coronavirus SARS-CoV-2 Trial (DAP-CORONA) COVID-19 (NCT04935476) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2021-11-22 |
| Phase 3 Study to Evaluate the Lot Consistency of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine (NCT05040789) | Medicago | 2021-11-22 |
| Study on Savolitinib Combined With Osimertinib in Treatment of Advanced NSCLC With MET Amplification (NCT05015608) | Hutchison Medipharma Limited | 2021-11-22 |
| Immunogenicity of Heterologous Versus Homologous Prime Boost Schedule With mRNA and Inactivated COVID-19 Vaccines (NCT05668065) | Institut Pasteur de Tunis | 2021-11-22 |
| AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department (NCT04669288) | University of Arizona | 2021-11-22 |
| A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction (NCT05126238) | Negovsky Reanimatology Research Institute | 2021-11-20 |
| Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection (NCT05109611) | Sanotize Research and Development corp. | 2021-11-20 |
| Ravulizumab Versus Placebo in Adult Participants With Dermatomyositis (NCT04999020) | Alexion Pharmaceuticals, Inc. | 2021-11-19 |
| Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas (NCT04924608) | AstraZeneca | 2021-11-19 |
| Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease (NCT04713982) | Vanderbilt University Medical Center | 2021-11-19 |
| Study Evaluating the Efficacy and Safety of WID-RGC20(Cariprazine) in Patients With Schizophrenia (NCT05168007) | Whanin Pharmaceutical Company | 2021-11-19 |
| The COCOA-PAD II Trial (NCT04794530) | Northwestern University | 2021-11-19 |
| Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3) (NCT05134974) | Ocuphire Pharma, Inc. | 2021-11-18 |
| A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry Eye (NCT05109702) | HanAll BioPharma Co., Ltd. | 2021-11-18 |
| A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer (NCT05091567) | Hoffmann-La Roche | 2021-11-18 |
| A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS) (NCT05130450) | Ionis Pharmaceuticals, Inc. | 2021-11-18 |
| Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis (NCT05134441) | Immunic AG | 2021-11-18 |
| A Study of Diroximel Fumarate (DRF) in Adult Participants From the Asia-Pacific Region With Relapsing Forms of Multiple Sclerosis (RMS) (NCT05083923) | Biogen | 2021-11-18 |
| Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter (NCT04856488) | Jan Calissendorff | 2021-11-18 |
| Open-Label Study of 18F-mFBG for Imaging Neuroblastoma (NCT04724369) | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 2021-11-18 |
| Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial (NCT04549311) | Sunnybrook Health Sciences Centre | 2021-11-18 |
| Simufilam 50 mg or 100 mg for Mild-to-Moderate Alzheimer's Disease (NCT05026177) | Cassava Sciences, Inc. | 2021-11-18 |
| Evaluation of the Early Use of Norepinephrine in Major Abdominal Surgery on Postoperative Organ Dysfunction (NCT05276596) | Centre Hospitalier Universitaire, Amiens | 2021-11-17 |
| VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial (NCT05139849) | Tiohundra AB | 2021-11-17 |
| A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia (NCT04812925) | argenx | 2021-11-17 |
| Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML (NCT05054543) | Apollomics Inc. | 2021-11-17 |
| Prevention of Maternal-fetal Cytomegalovirus Transmission After Primary Maternal Infection, GW ≤ 14 (PreCyssion) (NCT05170269) | Biotest | 2021-11-17 |
| Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors (NCT05145127) | Pfizer | 2021-11-17 |
| A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS) (NCT04958265) | Hoffmann-La Roche | 2021-11-17 |
| Study of Sacituzumab Govitecan (SG) Versus Docetaxel in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) (NCT05089734) | Gilead Sciences | 2021-11-17 |
| A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure (NCT04988295) | Janssen Research & Development, LLC | 2021-11-17 |
| Clinical Efficacy and Safety Evaluation of HCP1904-3 in Essential Hypertension Patients (NCT05199129) | Hanmi Pharmaceutical Company Limited | 2021-11-17 |
| A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age (NCT05127434) | ModernaTX, Inc. | 2021-11-17 |
| To Evaluate the Efficacy and Safety of JT-001 add-on in Paatients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin (NCT05101135) | Jeil Pharmaceutical Co., Ltd. | 2021-11-17 |
| Radiofrequency Ablation Versus I-131 for Solitary Autonomous Thyroid Nodules (NCT05142904) | Rijnstate Hospital | 2021-11-17 |
| A Study of Donanemab (LY3002813) Compared With Aducanumab in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 4) (NCT05108922) | Eli Lilly and Company | 2021-11-16 |
| Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in East Asian People Who Are Overweight or Living With Obesity (NCT05132088) | Novo Nordisk A/S | 2021-11-16 |
| Study of Efficacy and Safety of Ligelizumab in Adolescents and Adults With Chronic Inducible Urticaria Who Remain Symptomatic Despite Treatment With H1- Antihistamines (NCT05024058) | Novartis Pharmaceuticals | 2021-11-16 |
| A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221A (NCT05131997) | Addpharma Inc. | 2021-11-16 |
| High Dose Steroids in Children With Stroke (NCT04873583) | Insel Gruppe AG, University Hospital Bern | 2021-11-16 |
| A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is (NCT04786873) | AEterna Zentaris | 2021-11-16 |
| A Study To Assess the Safety of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence (NCT05134649) | AbbVie | 2021-11-16 |
| A Study of XZP-3287 in Combination With Fulvestrant in Patients With Advanced Breast Cancer (NCT05077449) | Xuanzhu Biopharmaceutical Co., Ltd. | 2021-11-16 |
| The Hemodynamic Effects of Different Volumes of Bupivacaine 0.25% Caudal Blocks in Pediatrics Undergoing Lower Abdominal Surgeries as Measured by Electrical Cardiometry (NCT05133687) | Kasr El Aini Hospital | 2021-11-15 |
| Effect of Jianpi Huatan Decoction on Advanced Colorectal Cancer (NCT05187481) | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 2021-11-15 |
| Perioperative Intravenous Lidocaine in Liver Surgery (NCT05153785) | Lund University Hospital | 2021-11-15 |
| Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer (NCT04940052) | Novartis Pharmaceuticals | 2021-11-15 |
| Cromolyn Sodium for Treatment of COVID-19 Pneumonia (NCT05077917) | Texas Tech University Health Sciences Center, El Paso | 2021-11-15 |
| EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN) (NCT05127525) | iRenix Medical, Inc. | 2021-11-15 |
| Adjuvant Anal Imiquimod Therapy in Anal HPV-lesions: AdAM-trial (NCT03289260) | Medical University Innsbruck | 2021-11-15 |
| To Evaluate the Efficacy and Safety in Patients With Dyslipidemia and Hypertension (NCT05331014) | JW Pharmaceutical | 2021-11-15 |
| A Trial of CP101 for the Prevention of Recurrent CDI (PRISM4) (NCT05153499) | Finch Research and Development LLC. | 2021-11-15 |
| A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders (NCT05112861) | Outlook Therapeutics, Inc. | 2021-11-15 |
| Motion Syros: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness (NCT04327661) | Vanda Pharmaceuticals | 2021-11-15 |
| Study on Precision Treatment of Diabetic Retinopathy Macular Edema Guided by Real-time OCT During Operation (NCT05138029) | Affiliated Hospital of Nantong University | 2021-11-15 |
| Investigation of Remimazolam in Children Undergoing Sedation for Medical Procedures (NCT04851717) | Acacia Pharma Ltd | 2021-11-15 |
| Testing P2Y12 Platelet Inhibitors Generics Beyond Bioequivalence (NCT05474053) | Cairo University | 2021-11-13 |
| Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis (NCT04925557) | State University of New York at Buffalo | 2021-11-13 |
| Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis (NCT05067127) | Apellis Pharmaceuticals, Inc. | 2021-11-12 |
| A Comparison of Three Regimens of Acute Pain Management: Methoxyflurane; Intranasal Fentanyl; Intravenous Morphine (NCT05137184) | Oslo University Hospital | 2021-11-12 |
| A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia (NCT05145413) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2021-11-12 |
| Safety and Immunogenicity of Adjuvanted SARS-CoV-2 (SCB-2019) Vaccine in Adults With Chronic Immune-Mediated Diseases (NCT05012787) | Clover Biopharmaceuticals AUS Pty | 2021-11-12 |
| Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer (NCT04628767) | National Cancer Institute (NCI) | 2021-11-12 |
| Moxifloxacin in Adjuvant Treatment of Patients With Operable Breast Cancer (NCT05114720) | Sun Yat-sen University | 2021-11-11 |
| SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma (NCT04967521) | Sarcoma Alliance for Research through Collaboration | 2021-11-11 |
| Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis (NCT05419427) | Lambda Therapeutic Research Ltd. | 2021-11-11 |
| Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features (NCT05255653) | Leiden University Medical Center | 2021-11-11 |
| Clinical Trial of YYC301 P3 for Treatment of Osteoarthritis of the Knee (NCT05362851) | Yooyoung Pharmaceutical Co., Ltd. | 2021-11-11 |
| Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying Therapy (NCT05028634) | Celgene | 2021-11-11 |
| Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries (NCT04979338) | Cedars-Sinai Medical Center | 2021-11-11 |
| Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer (NCT04774380) | AstraZeneca | 2021-11-11 |
| Sutimlimab (BIVV009) for the Adult Participants With Cold Agglutinin Disease (CAD) Who Have Completed Phase 3 Studies (CARDINAL or CADENZA) in Japan (NCT05132127) | Sanofi | 2021-11-11 |
| Clinical Efficacy of Platelet-Rich Plasma and Hyaluronic Acid Versus Hyaluronic Acid for Knee Osteoarthritis With MRI Analysis (NCT06636695) | Changi General Hospital | 2021-11-11 |
| Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute Pancreatitis (NCT04924868) | Hospital General Universitario de Alicante | 2021-11-10 |
| A Trial to Improve Quality of Life in People With Cirrhosis (NCT05061992) | University of Michigan | 2021-11-10 |
| A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007) (NCT05064059) | Merck Sharp & Dohme LLC | 2021-11-10 |
| Sisonke 2 - A COVID-19 Vaccine Boost Open Label Study. (NCT05148845) | Wits Health Consortium (Pty) Ltd | 2021-11-10 |
| Revefenacin in Chinese Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease(COPD) (NCT05046795) | Mylan Pharma UK Ltd. | 2021-11-10 |
| Circulating Tumour DNA guidEd Therapy for Stage IIB/C mElanoma After surgiCal resecTION (NCT04901988) | The Christie NHS Foundation Trust | 2021-11-08 |
| A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome (NCT04938427) | Takeda | 2021-11-08 |
| Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIR (NCT04672525) | Tourcoing Hospital | 2021-11-08 |
| A Study of Adeno-Associated Virus Serotype 8-Mediated Gene Transfer of Glucose-6-Phosphatase in Patients With Glycogen Storage Disease Type Ia (GSDIa) (NCT05139316) | Ultragenyx Pharmaceutical Inc | 2021-11-08 |
| A Study of Fezolinetant to Treat Hot Flashes in Women Going Through Menopause (NCT05033886) | Astellas Pharma Global Development, Inc. | 2021-11-08 |
| Treatment of Acute Ischemic Stroke (ReMEDy2 Trial) (NCT05065216) | DiaMedica Therapeutics Inc | 2021-11-07 |
| A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis (NCT05181137) | Reistone Biopharma Company Limited | 2021-11-05 |
| Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression (NCT05058287) | Hospital for Special Surgery, New York | 2021-11-05 |
| A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine (NCT05158348) | Kasr El Aini Hospital | 2021-11-05 |
| Study of BOTOX Injections in Prevention of Migraine in Adult Participants With Episodic Migraine (NCT05028569) | AbbVie | 2021-11-05 |
| Comparison of Nodal Staging in Endometrial Cancer (NCT04970368) | Frederick R. Ueland, M.D. | 2021-11-05 |
| Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1) (NCT04650074) | Hospices Civils de Lyon | 2021-11-05 |