| Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius) (NCT05158296) | Laboratoires Thea | 2021-12-08 |
| Efficacy and Safety of QGE031 (Ligelizumab) in Patients With Peanut Allergy (NCT04984876) | Novartis Pharmaceuticals | 2021-12-07 |
| Study Describing the Immunogenicity and Safety of Quadrivalent Recombinant Influenza Vaccine (RIV4) Versus a Licensed Quadrivalent-inactivated Influenza Vaccine (IIV4) (Fluarix® Quadrivalent) in Participants 18 Years of Age and Older in South Korea (NCT05144945) | Sanofi Pasteur, a Sanofi Company | 2021-12-07 |
| A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures (NCT05077904) | UCB Biopharma SRL | 2021-12-07 |
| Chlorpheniramine Nasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: ACCROS-I (NCT05449405) | Dr. Ferrer BioPharma | 2021-12-07 |
| A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery (NCT04702581) | Hospices Civils de Lyon | 2021-12-07 |
| Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes (NCT05054842) | Jiangsu HengRui Medicine Co., Ltd. | 2021-12-06 |
| A Trial of SHR1701 Plus Chemotherapy in Patients With Gastric or Gastroesophageal Cancer (NCT04950322) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2021-12-06 |
| A Phase 3 Clinical Study Patients With Androgenetic Alopecia (AGA) (NCT05135468) | Cutia Therapeutics（Wuxi）Co.,Ltd | 2021-12-06 |
| Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction (NCT05161221) | Rothman Institute Orthopaedics | 2021-12-06 |
| Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418) (NCT05008809) | Dominik Paul Modest | 2021-12-06 |
| Clinical Trial of Doxycycline VS BPG for Early Syphilis (SY-DOXY) (NCT04838717) | Assistance Publique - Hôpitaux de Paris | 2021-12-06 |
| EFFECTIVENESS of PROBIOTICS in ADULTS with MODERATE to SEVERE PERSISTENT ASTHMA (NCT06657066) | King Edward Medical University | 2021-12-06 |
| Durvalumab and Low-dose PCI vs Durvalumab and Observation in Radically Treated Patients With Stage III NSCLC (NVALT28) (NCT04597671) | Association NVALT Studies | 2021-12-06 |
| Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial (NCT05050084) | NRG Oncology | 2021-12-06 |
| Study of Anti-PD-1 Antibody SHR-1210 Plus Apatinib vs SHR-1210 as Second-Line Treatment of Advanced Esophageal Squamous Cell (NCT05049681) | Feng Wang | 2021-12-05 |
| AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation (NCT05035277) | Oslo University Hospital | 2021-12-04 |
| Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage (NCT04431999) | Direction Centrale du Service de Santé des Armées | 2021-12-04 |
| Mineralocorticoid Use in COVID-19 Patients (NCT05453214) | Ain Shams University | 2021-12-04 |
| To Evaluate the Efficacy and Safety of SAL056 for Postmenopausal Women With Osteoporosis at High Fracture Risk (NCT07028320) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2021-12-03 |
| OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE) (NCT05139810) | Ionis Pharmaceuticals, Inc. | 2021-12-03 |
| Efficacy and Safety of Tolebrutinib (SAR442168) Tablets in Adult Participants With Generalized Myasthenia Gravis (NCT05132569) | Sanofi | 2021-12-03 |
| Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Indian Women (NCT04773353) | Ferring Pharmaceuticals | 2021-12-03 |
| Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial (NCT03496883) | Joseph Broderick, MD | 2021-12-03 |
| Fight INflammation to Improve Outcome After Aneurysmal Subarachnoid HEmorRhage (NCT05132920) | University Hospital, Bonn | 2021-12-03 |
| Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects (NCT05172726) | Organon and Co | 2021-12-02 |
| Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcohol Use Disorder (NCT05093296) | Central Institute of Mental Health, Mannheim | 2021-12-02 |
| A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors (NCT05053139) | Novo Nordisk A/S | 2021-12-02 |
| Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET) (NCT05182970) | Karolinska Institutet | 2021-12-02 |
| Estrogen Administration for the Treatment of NASH in Postmenopausal Women (NCT04833140) | Massachusetts General Hospital | 2021-12-02 |
| Droperidol on Prevention of Cannabis Hyperemesis Syndrome (NCT05244460) | Mercy Health Ohio | 2021-12-02 |
| A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers (NCT05152147) | Jazz Pharmaceuticals | 2021-12-02 |
| A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH) (NCT05036135) | Aerovate Therapeutics | 2021-12-02 |
| [18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor (NCT04265209) | GE Healthcare | 2021-12-01 |
| Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers (NCT05194878) | Sun Yat-sen University | 2021-12-01 |
| Efficacy and Safety of Lima Association in the Control of Type II Diabetes Mellitus. (NCT03766750) | EMS | 2021-12-01 |
| Integrated Traditional Chinese and Clinical Medicine for Chronic Hepatitis B and Its Complication (NCT05128305) | Qianfoshan Hospital | 2021-12-01 |
| A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine (NCT05164172) | H. Lundbeck A/S | 2021-12-01 |
| Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern (NCT05168813) | COVID-19 Prevention Network | 2021-12-01 |
| Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema (NCT04898309) | AO GENERIUM | 2021-12-01 |
| Orelabrutinib Maintenance Therapy After ASCT in Primary Central Nervous System Lymphoma (NCT05334238) | Ruijin Hospital | 2021-12-01 |
| Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department (NCT05325580) | University of Monastir | 2021-12-01 |
| Safety and Feasibility of Argatroban As Anticoagulant in Adults with ECMO (NCT05226442) | Medical University of Vienna | 2021-12-01 |
| Local Betamethasone Versus Triamcinolone Injection in Management of Thyroid Eye Disease (NCT04976816) | Assiut University | 2021-12-01 |
| Effects of Low Protein Diet Supplemented With Ketoanalogues on Preservation of Kidney Function in Incremental Dialysis (NCT05030168) | Chulalongkorn University | 2021-12-01 |
| Shortened vs Standard Chemotherapy Combined With Immunotherapy for the Initial Treatment of Patients With High Tumor Burden Follicular Lymphoma (NCT05058404) | Fondazione Italiana Linfomi - ETS | 2021-12-01 |
| Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002) (NCT04807673) | Tianjin Medical University Cancer Institute and Hospital | 2021-12-01 |
| Clinical & Radiographic Evaluation of LSTR in Non-vital Primary Molars Using Two Different Vehicles (NCT05079802) | Ain Shams University | 2021-12-01 |
| A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1-antihistamines (NCT05032157) | Novartis Pharmaceuticals | 2021-12-01 |
| Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms. (NCT05096468) | Beijing Tiantan Hospital | 2021-12-01 |
| Low-dose Methotrexate for Change in Global Initiative for Asthma Step 5 Medications in Chronic Severe Asthma (NCT02124226) | University of Catania | 2021-12-01 |
| Adipose Stromal Cells Injection in the Myocardium for Induction of Revascularization (NCT04005989) | Hospital do Coracao | 2021-12-01 |
| Hip Denervation and Intra-articular Hydration in Damaged Hip in Axial Spondyloarthritis Patients (NCT05219084) | Sohag University | 2021-12-01 |
| Open Multicenter Study for Assessment of Efficacy and Safety of Molnupiravir in Adult Patients With COVID-19 (NCT05595824) | Promomed, LLC | 2021-12-01 |
| Tumescent Anesthesia Antibiotic Delivery (TAAD) (NCT03226626) | HK Surgical, Inc. | 2021-12-01 |
| Mechanical Thrombectomy of Medium Sized Vessels "M2 of MCA". (NCT05091320) | Assiut University | 2021-12-01 |
| Efficacy of Mirabegron Versus Tamsulosin Versus Solifenacin for Treatment of Ureteral Stents-Related Symptoms (NCT04325880) | Mansoura University | 2021-12-01 |
| Efficacy of Intralesional PRP in Treatment of Onychomycosis (NCT05128916) | Sohag University | 2021-12-01 |
| Effect of Topically Administered Levobupivacaine- Fentanyl Versus Levobupivacaine- Dexamethasone Combination in the Control of Pain After Endoscopic Sinus Surgery (NCT05145543) | Assiut University | 2021-12-01 |
| The Response to Intralesional IL-2 and/or BCG Treatment for Cutaneous Metastatic Melanoma (NCT03928275) | Carman Giacomantonio | 2021-12-01 |
| First-Line Treatment for Advanced Non-squamous Non-Small-Cell Lung Cancer With Negative Driver Gene: a Single-center, Single-Arm Trial (NCT05648071) | Qianfoshan Hospital | 2021-12-01 |
| Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children (NCT05313958) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2021-12-01 |
| Surgery Vs Chemoradiation for Oropharyngeal Cancer- A Phase II/III Integrated Design Randomized Control Trial (NCT05144100) | Tata Memorial Centre | 2021-12-01 |
| Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers (NCT04747054) | UNICANCER | 2021-12-01 |
| A Trial Comparing - Robotic Assisted Versus Laparoscopic Partial Nephrectomy For Small Renal Masses (NCT02933398) | St. Joseph's Healthcare Hamilton | 2021-12-01 |
| A Study to Assess Subcutaneous AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (NCT05152563) | Allakos Inc. | 2021-12-01 |
| Bintrafusp Alfa Program Rollover Study (NCT05061823) | EMD Serono Research & Development Institute, Inc. | 2021-12-01 |
| Tranexamic Acid During Excisional Burn Surgery (NCT05507983) | Maasstad Hospital | 2021-12-01 |
| Immunization With BCG Vaccine to Prevent Tuberculosis Infection (NCT04453293) | Henry M. Jackson Foundation for the Advancement of Military Medicine | 2021-12-01 |
| A Clinical Trial to Evaluate the Efficacy of RUTI® to Reduce the Severity of SARS-CoV-2 Infection (COVID-19) (NCT05115019) | PT. Innovative Pharma Solutions | 2021-12-01 |
| Cycled Testosterone Administration During Pulmonary Rehabilitation in Early Stage COPD (NCT03674320) | The University of Texas Medical Branch, Galveston | 2021-12-01 |
| Investigating the Effects of QVM149 on MRI Ventilation Defects (NCT04206761) | Dr. Grace Parraga | 2021-12-01 |
| A Study of Sotatercept in Participants With PAH WHO FC III or FC IV at High Risk of Mortality (MK-7962-006/ZENITH) (NCT04896008) | Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA | 2021-12-01 |
| An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C) (NCT05112965) | Hoffmann-La Roche | 2021-12-01 |
| Oral Baidi Quzhi Granule Combined With Ju Ying Cream for Acne Vulgaris (NCT05035979) | Shanghai Yueyang Integrated Medicine Hospital | 2021-12-01 |
| Rituxmab Versus IL-6 in Treating ILD (NCT05963048) | Assiut University | 2021-12-01 |
| Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis (NCT04303312) | Ghada zaki | 2021-12-01 |
| Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC) (NCT05136898) | UroGen Pharma Ltd. | 2021-11-30 |
| A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT) (NCT04770779) | Agios Pharmaceuticals, Inc. | 2021-11-30 |
| Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007) (NCT04938830) | Merck Sharp & Dohme LLC | 2021-11-30 |
| A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1 Antihistamines (NCT05030311) | Novartis Pharmaceuticals | 2021-11-30 |
| Pain Management After Surgery (NCT05154682) | Rothman Institute Orthopaedics | 2021-11-30 |
| A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Insulin Glargine Taken Daily With Insulin Aspart (COMBINE 3) (NCT05013229) | Novo Nordisk A/S | 2021-11-30 |
| (HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis (NCT04910685) | Blueprint Medicines Corporation | 2021-11-30 |
| A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II (NCT05208281) | AO GENERIUM | 2021-11-30 |
| A Study of the Efficacy and Safety of Secukinumab 300 mg in Patients With Thyroid Eye Disease (TED) (NCT04737330) | Novartis Pharmaceuticals | 2021-11-29 |
| Gemcitabine Versus Water Irrigation in Upper Tract Urothelial Carcinoma (NCT04865939) | University of Texas Southwestern Medical Center | 2021-11-29 |
| Efficacy and Safety of Fixed-dose Combination of Etoricoxib/Tramadol vs Acetaminophen/Tramadol for Acute Low Back Pain (NCT04968158) | Laboratorios Silanes S.A. de C.V. | 2021-11-29 |
| A Phase 3 Study of Efficacy and Safety of AK101 in Subjects With Psoriasis (NCT05120297) | Akeso | 2021-11-29 |
| The Effectiveness of a Topical Palmitoylethanolamide (PEA) Formulation (Levagen+) for Reducing Symptoms of Eczema (NCT05003453) | RDC Clinical Pty Ltd | 2021-11-29 |
| A Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia Congenita (NCT05180708) | Palvella Therapeutics, Inc. | 2021-11-29 |
| Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (NCT05105633) | University of Melbourne | 2021-11-29 |
| Journey Study: Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as Adjunctive Treatment for Schizophrenia (NCT05110157) | Neurocrine Biosciences | 2021-11-29 |
| Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure (NCT05165290) | TearClear Corp | 2021-11-29 |
| Safety and Immunogenicity of COVID-19 Vaccine, Inactivated in Healthy Population Aged From 3 to 11 Years (NCT05137418) | Sinovac Research and Development Co., Ltd. | 2021-11-27 |
| Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma (NCT04749108) | Institut du Cancer de Montpellier - Val d'Aurelle | 2021-11-26 |
| Clinical Trial to Evaluate the Efficacy and Safety of DWKH (NCT05683951) | Daewon Pharmaceutical Co., Ltd. | 2021-11-26 |
| InDuctIon TREatment with SubCuTaneous Infliximab for Crohn's Disease (NCT06059989) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2021-11-25 |
| A Study to Test How Well a Medicine Called Nintedanib Helps People in China With Progressive Lung Fibrosis (NCT05065190) | Boehringer Ingelheim | 2021-11-25 |
| Sulodexide in the Treatment of Chronic Primary Venous Disease of the Lower Extremities (NCT05005052) | Value Outcomes Ltd. | 2021-11-25 |