| Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases (NCT03367546) | Masonic Cancer Center, University of Minnesota | 2018-07-02 |
| Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease (NCT03629678) | Vanderbilt University Medical Center | 2018-07-01 |
| A Phase Ib Study of NVX-508 in Sickle Cell Disease (NCT03013426) | Amma Owusu-Ansah, MD | 2018-07-01 |
| Phosphodiesterase Type-5 Inhibitor Therapy in Sickle Cell People With Pulmonary Hypertension (NCT03572036) | National Heart, Lung, and Blood Institute (NHLBI) | 2018-06-20 |
| Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation (NCT03513328) | University of Florida | 2018-06-15 |
| Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031 (NCT03573882) | Pfizer | 2018-06-06 |
| Sleep Apnea in Sickle Cell Disease (NCT03753854) | Hospices Civils de Lyon | 2018-05-28 |
| Adherence to HU and HRQOL in Patients With Sickle Cell Disease: An Intervention Study Using HU-Go App (NCT04675645) | Ann & Robert H Lurie Children's Hospital of Chicago | 2018-05-15 |
| Quantitative MRI for Patients With Sickle Cell Disease Undergoing Hematopoietic Cell Transplant (NCT03458897) | University of Michigan | 2018-05-03 |
| Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease (NCT03587272) | Robert Nickel | 2018-04-17 |
| Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers (NCT02863068) | caterina P minniti | 2018-04-06 |
| Stem Cell Transplant in Patients With Severe Sickle Cell Disease (NCT03421756) | Kathleen Dorritie | 2018-03-29 |
| PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4) (NCT03492931) | AstraZeneca | 2018-03-28 |
| Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease (NCT03029468) | University of Pittsburgh | 2018-03-28 |
| Hemoglobin Desaturation in Sickle Cell Disease (NCT03908385) | University Hospitals Cleveland Medical Center | 2018-03-23 |
| Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease (NCT02987725) | University of California, Los Angeles | 2018-03-16 |
| Self-Management for Youth and Families Living With SCD - SMYLS (NCT03585543) | Medical University of South Carolina | 2018-03-16 |
| Distracting Through Procedural Pain and Distress (NCT04892160) | Medical College of Wisconsin | 2018-02-15 |
| Transfusion in Sickle Cell Disease: Screening of Sickle Cell Disease Trait in Blood Donors (NCT03405688) | Hanane EL KENZ | 2018-02-13 |
| Gene Transfer for Sickle Cell Disease (NCT03282656) | David Williams | 2018-02-13 |
| Transfusion in Sickle Cell Disease: Risk Factors for Alloimmunization (NCT03405402) | Hanane EL KENZ | 2018-02-13 |
| Stigma, Self-management, & Quality of Life in SCD (NCT03488264) | Duke University | 2018-02-13 |
| Evaluating Barriers to Stroke Screening and Prevention in Children With Sickle Cell Disease (NCT03621826) | Medical University of South Carolina | 2018-02-12 |
| Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD) (NCT03387033) | Duke University | 2018-02-05 |
| Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease (NCT03353584) | St. Jude Children's Research Hospital | 2018-02-05 |
| Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease (NCT03279094) | City of Hope Medical Center | 2018-02-02 |
| A Phase - IIa - IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD (NCT03247218) | HaEmek Medical Center, Israel | 2018-02-02 |
| Risk Factors for Allo-immunization in Sickle Cell Disease (NCT03401125) | Hanane EL KENZ | 2018-02-01 |
| Steroid Injection for Sickle Cell Arthropathy Pain Therapy (NCT05983055) | Salem Anaesthesia Pain Clinic | 2018-01-30 |
| A Study of IMR-687 in Adult Participants With Sickle Cell Anemia (Homozygous HbSS or Sickle-β0 Thalassemia) (NCT03401112) | Cardurion Pharmaceuticals, Inc. | 2018-01-26 |
| Omega-3 Fatty Acids in Sickle Cell Disease (NCT02947100) | Robin E. Miller | 2018-01-25 |
| HRV-B for Symptom Management in Sickle Cell Patients (NCT03383913) | Prisma Health-Upstate | 2018-01-22 |
| sPLA2 in EBC During Acute Chest Syndrome (NCT03250585) | Virginia Commonwealth University | 2018-01-19 |
| Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome (NCT03805581) | New York Medical College | 2018-01-12 |
| Sickle Cell Pro-Inflammatory Response to Interval Training Study (NCT03653676) | Ann & Robert H Lurie Children's Hospital of Chicago | 2018-01-02 |
| iCanCope With Sickle Cell Pain (NCT03201874) | Seattle Children's Hospital | 2018-01-01 |
| A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD) (NCT03285178) | Cyclerion Therapeutics | 2017-12-22 |
| Mesenchymal Stromal Cells for Haplo Hematopoietic Cell Transplantation for Sickle Cell Disease (NCT03298399) | Emory University | 2017-12-21 |
| Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer (NCT03333486) | Roswell Park Cancer Institute | 2017-12-07 |
| Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealth (NCT03344900) | St. Jude Children's Research Hospital | 2017-12-05 |
| Kidney Function in Sickle Cell Anemia (NCT03277547) | Kenneth Ataga MD | 2017-11-17 |
| Sleep and Pain in Sickle Cell Disease (NCT03150433) | Johns Hopkins University | 2017-11-05 |
| Age of Blood in Sickle Cell Transfusion (NCT03704922) | University of North Carolina, Chapel Hill | 2017-10-04 |
| Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507) (NCT03263559) | Medical College of Wisconsin | 2017-10-03 |
| Sickle Cell Disease: Targeting Alloantibody Formation Reduction; Risk Factors, and Genetics (NCT03288012) | Sanquin Research & Blood Bank Divisions | 2017-09-20 |
| Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease (NCT03243812) | Hospices Civils de Lyon | 2017-09-15 |
| The Implementation of the Automated Erythrocytapheresis in Egyptian Sickle Cell Disease Center (NCT03903289) | Ain Shams University | 2017-08-16 |
| HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease (NCT03240731) | Centre Hospitalier Intercommunal Creteil | 2017-08-10 |
| Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas (NCT03128515) | Indiana University | 2017-07-26 |
| Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients (NCT03226691) | National Heart, Lung, and Blood Institute (NHLBI) | 2017-07-25 |
| Sickle Cell Disease, Hemechip (NCT03948516) | University Hospitals Cleveland Medical Center | 2017-07-11 |
| Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor (NCT03214354) | University of Calgary | 2017-07-05 |
| Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease (NCT02675959) | New York Medical College | 2017-07-01 |
| Epidemiology of Silent and Overt Strokes in Sickle Cell Disease (NCT03376893) | Vanderbilt University Medical Center | 2017-06-02 |
| Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines (NCT03037021) | Duke University | 2017-05-31 |
| Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients (NCT03609840) | University of California, San Francisco | 2017-05-24 |
| Substudy of CADRE: for People With Extreme Phenotype: BIOCADRE (NCT03352986) | Cardiologie et Développement | 2017-05-15 |
| A Study to Compare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are Administered (NCT03126695) | AstraZeneca | 2017-05-12 |
| Examining the Knowledge, Attitudes, and Beliefs of Sickle Cell Disease Patients, Parents of Patients With Sickle Cell Disease, and Providers Towards the Integration of CRISPR in Clinical Care (NCT03167450) | National Human Genome Research Institute (NHGRI) | 2017-04-28 |
| A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease (NCT03132324) | Incyte Corporation | 2017-04-20 |
| A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases (NCT02633397) | Mark Gladwin | 2017-04-11 |
| Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease (NCT03077542) | National Heart, Lung, and Blood Institute (NHLBI) | 2017-04-06 |
| Home-based Assessment of PRO Measures in SCD Using A Smartphone App Platform: A Feasibility Study (NCT04678037) | Ann & Robert H Lurie Children's Hospital of Chicago | 2017-04-04 |
| Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease (NCT03121001) | University of Illinois at Chicago | 2017-03-20 |
| Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) (NCT02766465) | Medical College of Wisconsin | 2017-03-16 |
| Evaluation of Knowledge Among Adolescents With Sickle Cell Disease. (NCT03235011) | Adele CARLIER-GONOD | 2017-03-10 |
| Fetal Hemoglobin Induction Treatment Metformin (NCT02981329) | Baylor College of Medicine | 2017-03-02 |
| Dose-Finding Study of SC411 in Children With Sickle Cell Disease (NCT02973360) | Micelle BioPharma Inc | 2017-03-02 |
| Hemoglobinopathy Nursing Program and Pediatric Nursing Students (NCT05389891) | Beni-Suef University | 2017-02-27 |
| Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain Management (NCT03291613) | Klein Buendel, Inc. | 2017-01-15 |
| Hydoxycarbamide and L-Carnitine Therapy in Sickle Cell Anemia (NCT05081349) | Assiut University | 2017-01-10 |
| Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa (NCT02675790) | Vanderbilt University Medical Center | 2017-01-01 |
| A Pilot Study of Fecal Microbiome and Neutrophil Cellular Adhesion Molecules in Patients With Sickle Cell Disease (SCD) (NCT03007849) | Rhode Island Hospital | 2017-01-01 |
| Acute Kidney Injury in Patients With Sickle Cell Disease (NCT03105271) | University of Alabama at Birmingham | 2017-01-01 |
| Sickle-cell Disease Registry of the GPOH (NCT03327428) | University Hospital Heidelberg | 2016-12-15 |
| Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions (NCT02731157) | Duke University | 2016-12-01 |
| Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) (NCT03036813) | Pfizer | 2016-12-01 |
| SCD-PROMIS: A Software Platform to Enhance Self-efficacy and Patient-provider Engagement for Patients With Sickle Cell Pain (NCT03006718) | Julia Finkel | 2016-11-01 |
| Measurement of Cerebral Blood Flow Using Transcranial Doppler Ultrasound in Children With Sickle Cell Disease (NCT02090881) | Imperial College Healthcare NHS Trust | 2016-11-01 |
| A Study of IMR-687 in Healthy Adult Volunteers (NCT02998450) | Cardurion Pharmaceuticals, Inc. | 2016-10-18 |
| Monocytic Expression of Heme Oxidase-1 (HO-1) in Sickle Cell Patients and Correlation With the Humoral Immune Response to Vaccine and With Allo-immunization. (NCT03111589) | Francis Corazza | 2016-10-01 |
| Point-of-Delivery Prenatal Test Results Through mHealth to Improve Birth Outcome (NCT03027258) | University of Nevada, Las Vegas | 2016-09-01 |
| Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell Disease (NCT02960503) | Vanderbilt University | 2016-09-01 |
| An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001 (NCT03041909) | Global Blood Therapeutics | 2016-08-01 |
| Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II (NCT02560935) | Vanderbilt University Medical Center | 2016-07-19 |
| Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease (NCT02850406) | Pfizer | 2016-07-05 |
| Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease (NCT02867800) | Monica Bhatia | 2016-07-01 |
| Ketamine as an Adjuvant Therapy for Acute Vaso Occlusive Crisis in Pediatric Patients With Sickle Cell Disease (NCT02801292) | Augusta University | 2016-07-01 |
| Investigation of the Genetics of Hematologic Diseases (NCT02720679) | St. Jude Children's Research Hospital | 2016-06-17 |
| Endothelial Monocyte-activating Polypeptide-II in Egyptian Sickle Patients (NCT03903133) | Ain Shams University | 2016-06-01 |
| Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis (NCT03296345) | UCSF Benioff Children's Hospital Oakland | 2016-06-01 |
| Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya (NCT03293641) | Lucas Otieno Tina, MD MSc | 2016-05-20 |
| Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease (NCT02721472) | Theravia | 2016-05-17 |
| Study of Hydroxyurea to Treat Sickle Cell Disease (NCT02868138) | Mersin University | 2016-05-01 |
| HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen (NCT02776202) | National Guard Health Affairs | 2016-05-01 |
| Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease (NCT02678143) | Washington University School of Medicine | 2016-04-26 |
| Allogeneic SCT of CordIn™, in Patients With Hemoglobinopathies (NCT02504619) | Gamida Cell ltd | 2016-04-04 |
| The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient (NCT02729363) | University of Florida | 2016-04-01 |
| Neurovascular Determinants of Cognitive Function in Adults With Sickle Cell Disease (NCT02946905) | University of Pittsburgh | 2016-04-01 |
| Improving Quality by Maintaining Accurate Problems in the EHR (NCT02596087) | Brigham and Women's Hospital | 2016-04-01 |