| COVID-19 Testing in Underserved and Vulnerable Populations (NCT05315908) | Jesse Nodora | 2020-11-01 |
| Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease (NCT04584528) | Duke University | 2020-10-27 |
| Safety, Tolerability and Pharmacokinetics of FTX-6058 (NCT04586985) | Fulcrum Therapeutics | 2020-10-26 |
| Long-term Follow-up of Subjects with Sickle Cell Disease Treated with Ex Vivo Gene Therapy (NCT04628585) | Genetix Biotherapeutics Inc. | 2020-10-21 |
| Role of Inflammasome in Platelet Activation in Sickle Cell Disease Patient (NCT06986837) | Centre Hospitalier Universitaire de la Guadeloupe | 2020-10-14 |
| Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease. (NCT04244240) | Hospices Civils de Lyon | 2020-10-13 |
| The BENeFiTS Trial in Beta Thalassemia Intermedia (NCT04432623) | Phoenicia BioScience | 2020-10-05 |
| ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders (NCT04398628) | American Thrombosis and Hemostasis Network | 2020-09-30 |
| An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease (NCT04688411) | Ann & Robert H Lurie Children's Hospital of Chicago | 2020-09-28 |
| Preliminary Feasibility and Efficacy of Behavioral Intervention to Reduce Pain-Related Disability in Pediatric SCD (NCT04388241) | Children's National Research Institute | 2020-09-23 |
| Daily Vitamin D for Sickle-cell Respiratory Complications (NCT04170348) | Columbia University | 2020-09-15 |
| Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD) (NCT04443907) | Novartis Pharmaceuticals | 2020-08-25 |
| ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study (NCT04707235) | Theravia | 2020-08-21 |
| A Study of IMR-687 in Subjects With Sickle Cell Disease (NCT04474314) | Cardurion Pharmaceuticals, Inc. | 2020-08-13 |
| Designing an Implementation Strategy for Delivering Routine Mental Health Screening and Treatment (NCT04587661) | University of Pittsburgh | 2020-08-12 |
| A Study Aimed to Assess the Needs of Subjects With Sickle Cell Disease and Healthcare Professionals Managing Sickle Cell Disease Patients in Selected Nigerian Centres (NCT04505969) | Fondazione per la Ricerca Farmacologica Gianni Benzi Onlus | 2020-08-11 |
| Deferoxamine for Sickle Cell Chronic Leg Ulcer Treatment (NCT04058197) | TauTona Group | 2020-07-21 |
| SMYLS: A Self-management Program for Youth Living With Sickle Cell Disease (NCT04289311) | Medical University of South Carolina | 2020-07-13 |
| RHD Genotype Matched Red Cells for Anti-D (NCT04156906) | Children's Hospital of Philadelphia | 2020-07-08 |
| Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease. (NCT04293172) | AstraZeneca | 2020-06-30 |
| Prevalence of Osteoporosis in Sickle Cell Disease (NCT04299594) | Hospices Civils de Lyon | 2020-06-18 |
| Living With Sickle Cell Disease in the COVID-19 Pandemic (NCT04417673) | National Human Genome Research Institute (NHGRI) | 2020-06-15 |
| Qualitative Survey of Potential Exercise Activity in Adults With Sickle Cell Anemia (SCA) (NCT04181944) | Memorial Healthcare System | 2020-06-14 |
| Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. (NCT03919266) | Assistance Publique - Hôpitaux de Paris | 2020-06-02 |
| Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies (NCT04523376) | Timothy Olson | 2020-05-14 |
| Reduced Intensity Transplantation for Severe Sickle Cell Disease (NCT04362293) | St. Jude Children's Research Hospital | 2020-04-30 |
| ASH Research Collaborative Data Hub (NCT05775224) | ASH Research Collaborative | 2020-04-29 |
| High-flow Oxygen for Vaso-occlusive Pain Crisis (NCT03976180) | Assistance Publique - Hôpitaux de Paris | 2020-04-27 |
| ERN-EuroBloodNet Registry on Patients With Rare Red Blood Cell Defects and COVID-19 (NCT06831799) | Hospital Universitari Vall d'Hebron Research Institute | 2020-04-15 |
| Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease (NCT04207320) | University of Chicago | 2020-04-07 |
| The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria (NCT04800809) | Vanderbilt University Medical Center | 2020-04-01 |
| Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia (NCT04109820) | University of Pittsburgh | 2020-03-01 |
| Imatinib for Pain in Sickle Cell Anemia (NCT03997903) | Indiana University | 2020-02-26 |
| A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease (NCT04293185) | Genetix Biotherapeutics Inc. | 2020-02-14 |
| Acupuncture for Adults With Sickle Cell Disease (SCD): A Feasibility Study (NCT04156399) | University of Illinois at Chicago | 2020-01-15 |
| FOCUS for Pediatric Sickle Cell Disease and Cancer (NCT04075877) | Georgia State University | 2020-01-10 |
| Dose Escalation Study to Evaluate the Safety, Tolerability, PK and PD of Voxelotor in Patients With SCD (NCT04247594) | Pfizer | 2020-01-09 |
| Is the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative Complications (NCT04264871) | Queen Fabiola Children's University Hospital | 2020-01-01 |
| Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation (NCT04093986) | Children's Hospital Medical Center, Cincinnati | 2019-12-22 |
| Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED (NCT04150757) | Abigail Nixon | 2019-12-19 |
| Open-Label Extension of Voxelotor (NCT04188509) | Pfizer | 2019-11-18 |
| Safety and Efficacy of Gene Therapy of the Sickle Cell Disease by Transplantation of an Autologous CD34+ Enriched Cell Fraction That Contains CD34+ Cells Transduced ex Vivo With the GLOBE1 Lentiviral Vector Expressing the βAS3 Globin Gene in Patients With Sickle Cell Disease (DREPAGLOBE) (NCT03964792) | Assistance Publique - Hôpitaux de Paris | 2019-11-12 |
| Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia (NCT04301336) | Beni-Suef University | 2019-11-01 |
| Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions (NCT03938324) | Duke University | 2019-10-29 |
| A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease (NCT04166526) | Boston Children's Hospital | 2019-10-25 |
| Collect of Cord Blood From Subjects at Risk for Sickle Cell Disease, for the Purpose of Laboratory Research (NCT03876821) | Institut National de la Santé Et de la Recherche Médicale, France | 2019-10-23 |
| A Study of SHP655 (rADAMTS13) in Sickle Cell Disease (NCT03997760) | Shire | 2019-10-21 |
| Cerebral Oxygen Metabolism in Children (NCT04157179) | Washington University School of Medicine | 2019-10-17 |
| Comparison of Allogeneic Matched Related Haematopoietic Stem Cell Transplantation After a Reduced Intensity Conditioning Regimen With Standard of Care in Adolescents and Adults With Severe Sickle Cell Disease (NCT04046705) | Assistance Publique - Hôpitaux de Paris | 2019-10-15 |
| Health Literacy - Neurocognitive Screening in Pediatric SCD (NCT04917783) | Medical College of Wisconsin | 2019-09-25 |
| Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants (NCT03937817) | National Institute of Allergy and Infectious Diseases (NIAID) | 2019-09-25 |
| To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease (NCT04134299) | Axcella Health, Inc | 2019-09-25 |
| New Hemolysis Parameters in Sickle Cell Disease (NCT03040908) | Queen Fabiola Children's University Hospital | 2019-09-01 |
| Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease (NCT03933397) | Duke University | 2019-08-13 |
| Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease (NCT03978156) | Yale University | 2019-07-26 |
| Neuropathic Pain in Jamaicans With Sickle Cell Disease (NCT04015401) | The University of The West Indies | 2019-07-15 |
| Sickle Cell Pain: Intervention With Capsaicin Exposure (NCT03899246) | Children's Hospital of Michigan | 2019-07-03 |
| Sickle Cell Uric Acid (SCUA) - Cohort Repository (NCT04190888) | Virginia Commonwealth University | 2019-07-01 |
| Near Infrared Spectroscopy in Sickle Cell Pediatric Patients (NCT04031521) | Children's National Research Institute | 2019-06-26 |
| Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702) (NCT03904134) | Center for International Blood and Marrow Transplant Research | 2019-06-14 |
| Hydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere (NCT03825341) | St. Jude Children's Research Hospital | 2019-06-10 |
| SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial) (NCT03806452) | Theravia | 2019-05-28 |
| Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle Nephropathy (NCT03958643) | National Heart, Lung, and Blood Institute (NHLBI) | 2019-05-24 |
| An Extension Study of IMR-687 in Adult Patients With Sickle Cell Anemia (NCT04053803) | Imara, Inc. | 2019-05-22 |
| Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products (NCT03886753) | Children's Hospital of Philadelphia | 2019-05-15 |
| TAPS2 Transfusion Antenatally in Pregnant Women With SCD (NCT03975894) | Guy's and St Thomas' NHS Foundation Trust | 2019-05-02 |
| Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation (NCT04018937) | Emory University | 2019-03-22 |
| Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS) (NCT03528434) | Indiana University | 2019-03-14 |
| Exploring Adherence Monitoring in Sickle Cell Disease (NCT03708731) | St. Jude Children's Research Hospital | 2019-03-12 |
| A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease (NCT03653247) | Sangamo Therapeutics | 2019-03-06 |
| A Sickle CEll Disease ComplicatioN Trial (NCT02604368) | Micelle BioPharma Inc | 2019-03-01 |
| Hydroxyurea Optimization Through Precision Study (NCT03789591) | Lifespan | 2019-01-17 |
| Community Health Workers and mHealth for Sickle Cell Disease Care (NCT03648710) | Children's Hospital of Philadelphia | 2019-01-15 |
| LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study) (NCT03593395) | Wake Forest University Health Sciences | 2019-01-10 |
| A Blood Stem Cell Transplant for Sickle Cell Disease (NCT03249831) | City of Hope Medical Center | 2019-01-04 |
| Pharmacokinetics of Oral Hydroxyurea Solution (NCT03763656) | Nova Laboratories Limited | 2019-01-03 |
| A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients (NCT03815695) | Forma Therapeutics, Inc. | 2018-12-11 |
| Outcomes Mandate National Integration With Cannabis as Medicine (NCT03944447) | OMNI Medical Services, LLC | 2018-12-01 |
| Vitamin D Supplementation in Children With Sickle Cell Disease (NCT03417947) | St. Justine's Hospital | 2018-11-30 |
| Inhaled Mometasone to Promote Reduction in Vasoocclusive Events 2 (NCT03758950) | Jeffrey Glassberg | 2018-11-29 |
| A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease (NCT03745287) | Vertex Pharmaceuticals Incorporated | 2018-11-27 |
| Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease (NCT03694548) | Emory University | 2018-11-08 |
| Disseminating NIH Evidence Based Sickle Cell Recommendations in North Carolina (NCT03253211) | Duke University | 2018-11-06 |
| Impact on the Length of Stay in Incentive Spirometry and Pain in the Decompensation of Sickle Cell Disease: . (NCT04041180) | Centre Hospitalier Régional d'Orléans | 2018-11-06 |
| Hydroxyurea and Transfusion (NCT03644953) | Children's National Research Institute | 2018-10-30 |
| Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research (NCT03709303) | National Institutes of Health Clinical Center (CC) | 2018-10-29 |
| Acupuncture for Pain in Sickle Cell Disease (NCT04122378) | Deepika Darbari | 2018-10-23 |
| Early Check: Expanded Screening in Newborns (NCT03655223) | RTI International | 2018-10-15 |
| Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease (NCT03615924) | AstraZeneca | 2018-09-26 |
| Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease (NCT03664830) | City of Hope Medical Center | 2018-09-19 |
| Sickle Cell Disease, Neurocognitive Disorders, Social Participation (NCT04793854) | Centre Hospitalier Universitaire de la Guadeloupe | 2018-09-19 |
| PINPOINT: Gaming Technology for SCD Pain (NCT04579926) | Klein Buendel, Inc. | 2018-09-19 |
| Study of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell Disease (NCT03977532) | Assistance Publique Hopitaux De Marseille | 2018-09-14 |
| MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS) (NCT03556657) | University Hospitals Cleveland Medical Center | 2018-08-27 |
| Rifaximin to Modify the Disease Course in Sickle Cell Disease (NCT03719729) | New York Medical College | 2018-08-22 |
| Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial (NCT03462511) | Columbia University | 2018-08-15 |
| Efficacy of a Decision Aid for Hydroxyurea in Sickle Cell Disease (NCT03577691) | Emory University | 2018-08-03 |
| Assessing the Safety of Buprenorphine in People With Sickle Cell Disease (NCT03492099) | Johns Hopkins University | 2018-08-01 |
| Predictors and Outcomes in Patients With Sickle Cell Disease (NCT03431935) | St. Jude Children's Research Hospital | 2018-07-31 |
| Cerebrovascular Reserve and White Matter Disease in Patients with Chronic Anemia (NCT03715972) | Children's Hospital Los Angeles | 2018-07-15 |