| L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity (NCT05470998) | Tanta University | 2022-07-25 |
| Do Alemtuzumab Levels Predict T Cell Chimerism After MSD SCT for SCD? (NCT05905770) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2022-07-15 |
| TMLI and Alemtuzumab for Treatment of Sickle Cell Disease (NCT05384756) | City of Hope Medical Center | 2022-07-13 |
| Cooperative Assessment of Late Effects for SCD Curative Therapies (NCT05153967) | Vanderbilt University Medical Center | 2022-07-12 |
| A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001) (NCT05353647) | David Williams | 2022-07-12 |
| Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease. (NCT05470270) | Theravia | 2022-07-08 |
| Research Study Investigating How Well NDec Works in People With Sickle Cell Disease (NCT05405114) | Novo Nordisk A/S | 2022-07-07 |
| The Predictive Capacity of Machine Learning Models for Progressive Kidney Disease in Individuals With Sickle Cell Anemia (NCT05214105) | University of Tennessee | 2022-07-05 |
| Cognitive Remediation Intervention to Prepare for Transition of Care (NCT05336201) | University of Alabama at Birmingham | 2022-07-01 |
| Voxelotor Neurocognitive Function Study (NCT05228834) | Pfizer | 2022-06-24 |
| Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease (NCT05445128) | Ensoma | 2022-06-24 |
| Pilates Physical Activity in Sickle Cell Disease (NCT05519852) | Cairo University | 2022-06-22 |
| Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) (NCT05564845) | Dr. Marjon H. Cnossen MD PhD | 2022-06-20 |
| Alternative Dosing And Prevention of Transfusions (ADAPT) (NCT05662098) | Children's Hospital Medical Center, Cincinnati | 2022-06-16 |
| THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS) (NCT05033314) | University Health Network, Toronto | 2022-06-07 |
| Resolution of Sickle Cell Leg Ulcers With Voxelotor (NCT05561140) | Pfizer | 2022-05-30 |
| Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease (NCT05170412) | National Institutes of Health Clinical Center (CC) | 2022-05-26 |
| Efficacy of Designed Exercise Program on Pain and Quality of Sleeping in Patient With Sickle Cell Disease Anemia. (NCT05894161) | Imam Abdulrahman Bin Faisal University | 2022-05-20 |
| Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD) (NCT05329649) | Vertex Pharmaceuticals Incorporated | 2022-05-02 |
| A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease (NCT05348915) | Pfizer | 2022-03-29 |
| A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease (NCT04987489) | Forma Therapeutics, Inc. | 2022-03-28 |
| A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD). (NCT04912869) | Hoffmann-La Roche | 2022-03-26 |
| Pharmacokinetics and Pharmacodynamics of Rifaximin Novel Formulations in Patients With Sickle Cell Disease (NCT05098028) | Bausch Health Americas, Inc. | 2022-03-22 |
| Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients (NCT05255445) | Westat | 2022-03-16 |
| A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) (NCT05075824) | Hoffmann-La Roche | 2022-03-09 |
| Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme (NCT05143021) | Vanderbilt University Medical Center | 2022-02-14 |
| A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP) (NCT05031780) | Agios Pharmaceuticals, Inc. | 2022-02-11 |
| A Study to Learn About Sickle Cell Disease In Adult Patients (NCT05407805) | Pfizer | 2022-02-10 |
| Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease (NCT04983654) | Hospices Civils de Lyon | 2022-02-09 |
| Oxbryta® Product Registry An Observational Study Designed to Evaluate the Effect of Oxbryta in Individuals With SCD (NCT04930445) | Pfizer | 2022-02-04 |
| Nasopharyngeal Bacterial Carriage and Antibiotic Resistance in Children With Sickle Cell Disease in Ile-De-France (NCT05197205) | Assistance Publique - Hôpitaux de Paris | 2022-02-01 |
| Cutaneous Hydration Assessment in SCD (NCT05210114) | Enrico Novelli | 2022-01-21 |
| A Low-Interventional Study of an Electronic Sickle Cell Disease Patient Reported Outcomes in Sickle Cell Participants (NCT06503458) | Sanguine Biosciences | 2022-01-19 |
| Interest of Famotidine in Children With Sickle Cell Disease (NCT05084521) | Assistance Publique - Hôpitaux de Paris | 2022-01-12 |
| Algorithm for Apherisis Monitoring and Prescription Assistance in Sickle Cell Patients (ALGODREP) (NCT04076683) | Etablissement Français du Sang | 2022-01-05 |
| Glutamine Role in Preventing Vaso-occlusive Crisis Among SCD Patients (NCT05371184) | Ain Shams University | 2022-01-04 |
| Pilot Evaluation of a Motivational Interviewing Intervention Targeting Adherence Behaviors in Youth With Sickle Cell Disease (NCT04877054) | Johns Hopkins All Children's Hospital | 2021-12-30 |
| Severe Acute Respiratory Syndrome CoV 2 COVID-19 Survey and Vaccination Coverage in the Sickle Cell Population in Ile-De-France (NCT05153044) | Assistance Publique - Hôpitaux de Paris | 2021-12-30 |
| A Study of a Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive Crises (NCT04927247) | Pfizer | 2021-12-09 |
| COVID-19 Vaccine Response in Sickle Cell Disease (NCT05139992) | ASH Research Collaborative | 2021-12-01 |
| Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain (NCT04906447) | University of Illinois at Chicago | 2021-11-24 |
| Study to Assess Efficacy and Safety of VIT-2763 (Vamifeport) in Subjects With Sickle Cell Disease (NCT04817670) | Vifor (International) Inc. | 2021-11-18 |
| Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease (NCT04819841) | Kamau Therapeutics | 2021-11-15 |
| Prospective, Observational Study in Sickle Cell Disease Patients on Crizanlizumab Treatment in Middle East Countries and India (NCT05020873) | Novartis Pharmaceuticals | 2021-11-04 |
| Biotin-RBC Transfusion in SCD (NCT04426591) | Marianne Yee | 2021-10-29 |
| Home-Based Intervention for Chronic Pain in Adults With Sickle Cell Disease (NCT04906707) | Emory University | 2021-10-27 |
| Characteristics and Treatment Patterns of Patients With Sickle Cell Disease in Globin Research Network for Data and Discovery Registry (NCT06662812) | Novartis | 2021-10-06 |
| A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises (NCT04935879) | Pfizer | 2021-10-04 |
| Interest of Nutritional Care of Children With Sickle Cell Disease on Bone Mineral Density and Body Composition (NCT04754711) | Centre Hospitalier Régional d'Orléans | 2021-09-23 |
| Fitness Trial in Adults With Sickle Cell Disease (SCD Fit): A Feasibility Study (NCT04772391) | Memorial Healthcare System | 2021-09-01 |
| Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease (NCT05012631) | Children's Hospital Medical Center, Cincinnati | 2021-09-01 |
| Characteristics of Patients With Sickle Cell Disease (NCT05494541) | Novartis Pharmaceuticals | 2021-08-30 |
| Patient Characteristics and Treatment Patterns From Early Crizanlizumab Use in Real-world Setting: Preliminary Analysis From Select Sickle Cell Centers (NCT05833022) | Novartis Pharmaceuticals | 2021-07-30 |
| Low Dose Iron Chelation as TReatment of Oxidative Damage in Sickle Cell Disease (NCT05392101) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2021-07-20 |
| US Phase I Study of ECT-001-CB in Patients With Sickle-Cell Disease (NCT04594031) | ExCellThera inc. | 2021-07-13 |
| A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD (NCT04201210) | University of Regensburg | 2021-06-30 |
| Metabolic and Hemodynamic Reserve in Pediatric SCA (NCT04406818) | Washington University School of Medicine | 2021-06-30 |
| Integrative Medicine in Pain Management in Sickle Cell Disease (NCT05045820) | Indiana University | 2021-06-29 |
| Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial (NCT04839354) | Claudia R. Morris | 2021-06-21 |
| Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study (NCT04657822) | Novartis Pharmaceuticals | 2021-06-10 |
| Prevalence and Pathophysiology of Systemic Arterial Pressure Abnormalities in Childhood Sickle Cell Disease (NCT04911049) | Assistance Publique - Hôpitaux de Paris | 2021-06-01 |
| A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD) (NCT04983264) | Pfizer | 2021-05-21 |
| Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell Disease (NCT04285827) | CSL Behring | 2021-05-20 |
| Stroke Prevention in Young Adults With Sickle Cell Anemia (NCT04808778) | Vanderbilt University Medical Center | 2021-05-17 |
| Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia (NCT04380610) | University of Alabama at Birmingham | 2021-05-12 |
| A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY) (NCT04853576) | Editas Medicine, Inc. | 2021-05-04 |
| A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease (NCT04484272) | University of Florida | 2021-04-29 |
| Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease (NCT04476277) | National Heart, Lung, and Blood Institute (NHLBI) | 2021-04-19 |
| AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion (NCT04099966) | Mitchell Cairo | 2021-04-01 |
| Retrospective Real World Oxbryta® Data Collection and Analysis Study (NCT04930328) | Pfizer | 2021-03-20 |
| Avascular Bone Necrosis in Sickle Cell Disease: a Pediatric Study. (NCT05203991) | San Luigi Gonzaga Hospital | 2021-03-18 |
| A Voxelotor for Sickle Cell Anemia Patients at Highest Risk for Progression of Chronic Kidney Disease (NCT04335721) | University of Illinois at Chicago | 2021-03-16 |
| DREPAMASSE Study - Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass Spectrometry (NCT03985501) | Hospices Civils de Lyon | 2021-03-16 |
| Evaluation of Virtual Reality to Save Morphinic in the Treatment of Vaso-occlusive Seizures of Sickle Cell Patients Consulting in the Emergency Room (NCT04756375) | Assistance Publique - Hôpitaux de Paris | 2021-03-04 |
| The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD. (NCT04691323) | Ann & Robert H Lurie Children's Hospital of Chicago | 2021-03-02 |
| Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT (NCT04629430) | University of Virginia | 2021-02-19 |
| Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France (NCT04694976) | Hospices Civils de Lyon | 2021-02-04 |
| Safety Evaluation of DREPADOM - Home Care Services and Hospitalizations for Sickle Cell Disease Patients (NCT05649280) | Soutien aux Actions contre les Maladies du Globule Rouge | 2021-02-01 |
| A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS) (NCT04624659) | Forma Therapeutics, Inc. | 2021-01-29 |
| Building Adaptive Coping and Knowledge to Improve Daily Life (NCT04602728) | Emory University | 2021-01-27 |
| Sickle Cell Anemia WE CARE (NCT03716726) | Boston Medical Center | 2021-01-21 |
| A Long-term Follow-up Study in Participants Who Received CTX001 (NCT04208529) | Vertex Pharmaceuticals Incorporated | 2021-01-20 |
| SELF-BREATHE RCT for Chronic Breathlessness (NCT04574050) | King's College Hospital NHS Trust | 2021-01-11 |
| Primary Prevention of Stroke in Children With Sickle Cell Anaemia in Nigeria in the Community (NCT05434000) | Barau Dikko Teaching Hospital | 2021-01-06 |
| Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease Patients (NCT04684381) | Emmaus Medical, Inc. | 2021-01-04 |
| Evaluation of Left Ventricular Function by Speckle Tracking Echocardiography in Patient Hospitalised in Intensive Care Unit for Vaso-occlusive Crisis (NCT04864041) | Bicetre Hospital | 2021-01-01 |
| Evaluation of Therapeutic Adherence to Inciting Spirometry in Sickle Cell Patients (NCT04667325) | Centre Hospitalier Intercommunal Creteil | 2021-01-01 |
| Medication Adherence and Non-adherence in Adults With Rare Disease (NCT04541875) | Xperiome | 2021-01-01 |
| Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies (NCT04776850) | M.D. Anderson Cancer Center | 2020-12-29 |
| Actigraphy Improvement With Voxelotor (ActIVe) Study (NCT04400487) | Pfizer | 2020-12-21 |
| Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders (NCT04416178) | St. Jude Children's Research Hospital | 2020-12-17 |
| A Study to Evaluate GBT021601 in Single and Multiple Doses in Healthy Participants (NCT05036512) | Pfizer | 2020-12-09 |
| Utilizing A Single Session Problem-Solving Intervention With Caregivers of Pediatric Patients Receiving Chronic Transfusion to Treat Sickle Cell Disease (NCT04606160) | University of Texas Southwestern Medical Center | 2020-12-09 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat (NCT04610866) | National Heart, Lung, and Blood Institute (NHLBI) | 2020-12-09 |
| Isoquercetin in Sickle Cell Anemia (NCT04474626) | Jeffrey Zwicker, MD | 2020-12-01 |
| Crizanlizumab Pregnancy Outcomes Intensive Monitoring (NCT07554547) | Novartis Pharmaceuticals | 2020-11-15 |
| Integrative Diagnosis for SCD and Other RADs (NCT07206095) | Hospital Universitari Vall d'Hebron Research Institute | 2020-11-13 |
| Exercise in Child Health (NCT05359991) | University of California, Irvine | 2020-11-12 |
| Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease (NCT04218084) | Pfizer | 2020-11-11 |
| Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease (NCT04514510) | National Heart, Lung, and Blood Institute (NHLBI) | 2020-11-02 |