| The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT (NCT02729350) | University of Florida | 2016-04-01 |
| Evaluating Thromboelastography (TEG) and ETP in Sickle Adults (NCT02770534) | Guy's and St Thomas' NHS Foundation Trust | 2016-04-01 |
| Coordinated HEalthcare for Complex Kids (NCT04057521) | University of Illinois at Chicago | 2016-04-01 |
| Improving Self-Management in Adolescents With Sickle Cell Disease (NCT02851615) | Children's Hospital Medical Center, Cincinnati | 2016-03-31 |
| Arginine Therapy for Sickle Cell Disease Pain (NCT02536170) | Emory University | 2016-02-01 |
| A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome (NCT02697240) | University of Mississippi Medical Center | 2016-02-01 |
| Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT) (NCT03609814) | University of California, San Francisco | 2016-01-26 |
| Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease (NCT02433158) | GlycoMimetics Incorporated | 2015-12-16 |
| A Study of Oral L-citrulline in Sickle Cell Disease (NCT02659644) | University of Mississippi Medical Center | 2015-12-01 |
| Sub-dissociative Intranasal Ketamine for Pediatric Sickle Cell Pain Crises (NCT02573714) | Cameroon Baptist Convention Health | 2015-12-01 |
| Dense Red Blood Cells in Sickle Cell Children (NCT02887118) | Centre Hospitalier Intercommunal Creteil | 2015-12-01 |
| Hematopoietic Stem Cell Transplant for Sickle Cell Disease (NCT02065596) | Case Comprehensive Cancer Center | 2015-10-19 |
| Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH) (NCT02522104) | Theravia | 2015-09-03 |
| A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease (NCT02630394) | University of Mississippi Medical Center | 2015-09-01 |
| Evaluation of the Hemostatic Potential in Sickle Cell Disease Patients (NCT02565082) | Brugmann University Hospital | 2015-09-01 |
| Prevention of Vaso-occlusive Painful Crisis by Using Omega-3 Fatty Acid Supplements (NCT02525107) | Sultan Qaboos University | 2015-09-01 |
| Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients (NCT03609827) | University of California, San Francisco | 2015-09-01 |
| A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease (NCT02620488) | University of California, Los Angeles | 2015-09-01 |
| A Single-Dose Relative Bioavailability Study Of GBT440 300 mg Capsules in Healthy Subjects (NCT02567695) | Global Blood Therapeutics | 2015-09-01 |
| Drug Interaction Study of GBT440 With Caffeine, S-warfarin, Omeprazole, and Midazolam in Healthy Subjects (NCT02567682) | Global Blood Therapeutics | 2015-09-01 |
| Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients (NCT02615847) | University of Zurich | 2015-08-01 |
| A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease (NCT02482298) | AstraZeneca | 2015-07-09 |
| SMART Mobile Application Technology Utilization in the Treatment of Sickle Cell Disease Post Day Hospital Discharge (NCT02475993) | Duke University | 2015-07-01 |
| Macitentan in Pulmonary Hypertension of Sickle Cell Disease (NCT02651272) | Boston University | 2015-07-01 |
| Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD (NCT02515838) | Modus Therapeutics AB | 2015-07-01 |
| Music Therapy in Sickle Cell Transition Study (NCT02466555) | University Hospitals Cleveland Medical Center | 2015-06-01 |
| Evaluation of Repeat Administration of Purified Poloxamer 188 (NCT02449616) | Mast Therapeutics, Inc. | 2015-06-01 |
| Study of Methodologies to Measure Blood Flow and Oxygenation in Adults With Sickle Cell Disease (NCT02447627) | Bioverativ Therapeutics Inc. | 2015-06-01 |
| Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias (NCT02443545) | ApoPharma | 2015-05-21 |
| Glucose Metabolism in Sickle Cell Disease (NCT02922296) | University of Illinois at Chicago | 2015-05-01 |
| Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease (NCT02447874) | Emory University | 2015-05-01 |
| Comparison of Patient Centered Outcomes for People With Sickle Cell Disease in the Acute Care Setting (NCT02411396) | Johns Hopkins University | 2015-04-01 |
| Preventing Sickle Cell Kidney Disease (NCT02373241) | University of Alabama at Birmingham | 2015-04-01 |
| Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease (NCT02222246) | Duke University | 2015-03-15 |
| Sickle Cell Anemia and Cerebral Microcirculation : Multimodal Exploration (NCT02909283) | Imagine Institute | 2015-03-02 |
| Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications (NCT02384590) | University of Pittsburgh | 2015-03-01 |
| Dose-Escalation Study of SCD-101 in Sickle Cell Disease (NCT02380079) | Invenux, LLC | 2015-02-01 |
| Apixaban in Patients With Sickle Cell Disease (NCT02179177) | Nirmish Shah | 2015-01-01 |
| Safety and Pharmacokinetics of SANGUINATE™ in Sickle Cell Disease (SCD) Patients (NCT01374165) | Prolong Pharmaceuticals | 2015-01-01 |
| Decision Aid for Therapeutic Options In Sickle Cell Disease (NCT02326597) | Emory University | 2015-01-01 |
| A Dose Escalation Study of Intravenous L-citrulline in Steady-state Sickle Cell Disease (NCT02314689) | Suvankar Majumdar | 2015-01-01 |
| Contraception in Women With Sickle Cell Disease (NCT02594462) | University of Sao Paulo | 2015-01-01 |
| Stem Cell Gene Therapy for Sickle Cell Disease (NCT02247843) | Donald B. Kohn, M.D. | 2014-12-01 |
| A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell Disease (NCT02285088) | Global Blood Therapeutics | 2014-12-01 |
| Biological, Genetic and Environmental Involved in the Complications of Sickle Cell Disease (NCT04205123) | Erasme University Hospital | 2014-10-20 |
| Vitamin D3 in Patients With Sickle Cell Disease (NCT03012555) | Icahn School of Medicine at Mount Sinai | 2014-10-01 |
| Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease (NCT02394899) | The University of The West Indies | 2014-10-01 |
| A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease (NCT02261480) | St. Jude Children's Research Hospital | 2014-10-01 |
| Sickle Cell Disease Biofluid Chip Technology (SCD BioChip) (NCT02824471) | University Hospitals Cleveland Medical Center | 2014-10-01 |
| Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease (NCT02193191) | Memorial Sloan Kettering Cancer Center | 2014-09-17 |
| Sleep Study in Adult Patients With Major Sickle Cell Disease With Paroxysmal Nocturnal Events (NCT02539771) | Assistance Publique - Hôpitaux de Paris | 2014-09-17 |
| Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell Disease (NCT02227472) | St. Jude Children's Research Hospital | 2014-09-08 |
| Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies (NCT02179359) | Masonic Cancer Center, University of Minnesota | 2014-09-02 |
| Novel Use Of Hydroxyurea in an African Region With Malaria (NCT01976416) | Indiana University | 2014-09-01 |
| Music Therapy in Sickle Cell Pain Mixed Methods Study (NCT02270060) | University Hospitals Cleveland Medical Center | 2014-09-01 |
| Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease (NCT02225132) | National Heart, Lung, and Blood Institute (NHLBI) | 2014-08-23 |
| Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease (NCT01771731) | University of California, San Francisco | 2014-08-01 |
| Cerebrovascular Reserve Measurements in Sickle Cell Disease (NCT02824406) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2014-08-01 |
| ElectroNic Hydroxyurea AdhereNCE: A Strategy to Improve Hydroxyurea Adherence in Patients With Sickle Cell Disease (NCT02578017) | Nationwide Children's Hospital | 2014-07-01 |
| PATient Navigator to rEduce Readmissions (NCT02114515) | University of Illinois at Chicago | 2014-07-01 |
| Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial (NCT02187445) | Vanderbilt University | 2014-06-01 |
| Realizing Effectiveness Across Continents With Hydroxyurea (REACH) (NCT01966731) | Children's Hospital Medical Center, Cincinnati | 2014-06-01 |
| Patient Centered Comprehensive Medication Adherence Management System in Patients With Sickle Cell Disease (NCT02371720) | Emory University | 2014-06-01 |
| Sickle Cell Disease (SCD) Decision Aid (NCT03224429) | Emory University | 2014-05-15 |
| Medication Adherence in Youth With Sickle Cell Disease (SCD) (NCT02143076) | St. Jude Children's Research Hospital | 2014-05-01 |
| Use of Mobile Technology for Intensive Training in Medication Management (NCT02133560) | Duke University | 2014-05-01 |
| Feasibility Study of Unfractionated Heparin in Acute Chest Syndrome (NCT02098993) | Craig Seaman | 2014-05-01 |
| Sickle Cell Hemoglobinopathies and Bone Health (NCT02306993) | UConn Health | 2014-05-01 |
| Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure (NCT02105766) | National Heart, Lung, and Blood Institute (NHLBI) | 2014-04-21 |
| Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias (NCT02041299) | ApoPharma | 2014-04-17 |
| Sickle Cell Clinical Research and Intervention Program (NCT02098863) | St. Jude Children's Research Hospital | 2014-04-15 |
| SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD (NCT02013375) | Damiano Rondelli, MD | 2014-04-10 |
| Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease (NCT02061202) | Jeffrey Glassberg | 2014-03-01 |
| Androgen Regulation of Priapism in Sickle Cell Disease (NCT01940718) | Johns Hopkins University | 2014-03-01 |
| Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease (NCT02410811) | Children's Hospital Medical Center, Cincinnati | 2014-01-31 |
| Sleep Respiratory Disorders Evaluation in Sickle Cell Disease Children (NCT01565954) | Assistance Publique - Hôpitaux de Paris | 2014-01-01 |
| Bone Marrow Transplant With Abatacept for Non-Malignant Diseases (NCT01917708) | Emory University | 2014-01-01 |
| Evaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell Disease (NCT01987908) | Baxalta now part of Shire | 2013-12-03 |
| Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital. (NCT02608580) | Brugmann University Hospital | 2013-12-01 |
| Nitrous Oxide Analgesia Vaso-occlusive Crisis (NCT01891812) | Columbia University | 2013-11-12 |
| Feasibility of a Stress Reduction Intervention Study in Sickle Cell Disease (NCT02501447) | University of Illinois at Chicago | 2013-11-01 |
| Added Value of Speckle Tracking in the Evaluation of Patients With Sickle Cell Disease (NCT02394431) | Brugmann University Hospital | 2013-11-01 |
| Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis (NCT01932554) | St. Louis University | 2013-11-01 |
| Evaluation of Sickle Cell Liver Disease (NCT01950429) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2013-10-16 |
| Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell Disease (NCT01959958) | St. Jude Children's Research Hospital | 2013-10-01 |
| Novel Dose Escalation to Predict Treatment With Hydroxyurea (NCT02042222) | Baylor College of Medicine | 2013-10-01 |
| Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis (NCT01925001) | Sangart | 2013-10-01 |
| Uganda Sickle Surveillance Study (US-3) (NCT06301893) | Children's Hospital Medical Center, Cincinnati | 2013-09-07 |
| Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT (NCT02029742) | Columbia University | 2013-09-01 |
| Web-MAP Intervention for Youth With Sickle Cell Disease (NCT02511769) | Connecticut Children's Medical Center | 2013-09-01 |
| Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease (NCT01732718) | University of North Carolina, Chapel Hill | 2013-09-01 |
| Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease (NCT01895998) | Duke University | 2013-08-01 |
| Improving Disease Knowledge in Adolescents With Sickle Cell Disease (NCT01945073) | The University of The West Indies | 2013-08-01 |
| Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises (NCT01895361) | Reprixys Pharmaceutical Corporation | 2013-07-01 |
| A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease (NCT02151526) | Genetix Biotherapeutics Inc. | 2013-06-07 |
| Exhaled Carbon Monoxide as a Marker of Hemolysis in Sickle Cell Disease- an Exploratory Study (NCT01888614) | University Hospitals Cleveland Medical Center | 2013-06-01 |
| Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC) (NCT01737814) | Mast Therapeutics, Inc. | 2013-05-01 |
| Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease (NCT01835496) | ApoPharma | 2013-05-01 |
| Non-Myeloablative Conditioning and Bone Marrow Transplantation (NCT01850108) | Vanderbilt-Ingram Cancer Center | 2013-05-01 |
| Study of SANGUINATE™ Versus Hydroxyurea in Sickle Cell Disease (SCD) Patients (NCT01848925) | Prolong Pharmaceuticals | 2013-05-01 |