| A Study to Learn How Safe ACT-777991 is and How Well it Works in Adults With Non-segmental Vitiligo (NCT07667569) | Idorsia Pharmaceuticals Ltd. | 2026-06-01 |
| A Drug-drug Interaction Trial in Healthy Female Participants to Investigate the Effect of Aprocitentan on Combined Hormonal Contraceptives (NCT06799884) | Idorsia Pharmaceuticals Ltd. | 2025-01-18 |
| Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ® (NCT06498128) | Idorsia Pharmaceuticals Ltd. | 2024-11-21 |
| Database Study to Provide Information on Pregnancy and Infant Outcomes Among Women Exposed to QUVIVIQ (Daridorexant) (NCT06393504) | Idorsia Pharmaceuticals Ltd. | 2023-11-30 |
| A Phase 1 Trial to Investigate the Biological Equivalence of 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese Participants (NCT05877222) | Idorsia Pharmaceuticals Ltd. | 2023-06-23 |
| A Study to Find Out if Daridorexant is Safe and Efficacious in Patients With Insomnia and Comorbid Nocturia (NCT05597020) | Idorsia Pharmaceuticals Ltd. | 2023-02-16 |
| A Study to Measure Daridorexant in Breast Milk of Healthy Lactating Women (NCT05632393) | Idorsia Pharmaceuticals Ltd. | 2023-01-16 |
| A Study of the Effect of Daridorexant on Nighttime Body Posture, the Noise Level Required to Wake up, and the Ability to Remember Words Previously Presented (NCT05702177) | Idorsia Pharmaceuticals Ltd. | 2023-01-05 |
| A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male Subjects (NCT05549531) | Idorsia Pharmaceuticals Ltd. | 2022-10-01 |
| Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia Disorder (NCT05423717) | Idorsia Pharmaceuticals Ltd. | 2022-09-06 |
| A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Dabigatran and Rosuvastatin in Healthy Male Subjects (NCT05480475) | Idorsia Pharmaceuticals Ltd. | 2022-09-03 |
| A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Midazolam and Warfarin in Healthy Male Subjects (NCT05480488) | Idorsia Pharmaceuticals Ltd. | 2022-08-23 |
| A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During Sleep (NCT05458193) | Idorsia Pharmaceuticals Ltd. | 2022-08-17 |
| A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy Subjects (NCT05254548) | Idorsia Pharmaceuticals Ltd. | 2022-02-18 |
| Bioequivalence Study of Different Aprocitentan Tablet Formulations (NCT05196399) | Idorsia Pharmaceuticals Ltd. | 2022-02-02 |
| Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470 (NCT05123820) | Idorsia Pharmaceuticals Ltd. | 2021-11-13 |
| A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control Subjects (NCT04899219) | Idorsia Pharmaceuticals Ltd. | 2021-06-16 |
| Multicenter Study to Evaluate the Efficacy and Safety of Oral ACT-539313 in the Treatment of Adults With Moderate to Severe Binge Eating Disorder (NCT04753164) | Idorsia Pharmaceuticals Ltd. | 2021-02-16 |
| A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects (NCT04798209) | Idorsia Pharmaceuticals Ltd. | 2021-01-29 |
| A Placebo-controlled Phase 1 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects (NCT04608513) | Idorsia Pharmaceuticals Ltd. | 2020-11-16 |
| A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478 (NCT04452006) | Idorsia Pharmaceuticals Ltd. | 2020-07-20 |
| Study in Healthy Subjects to Examine the Safety and Tolerability of ACT-1004-1239 Given as Multiple, Gradually Increasing Doses and to Examine the Effects of ACT-1004-1239 on the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-1004-1239 (NCT04286750) | Idorsia Pharmaceuticals Ltd. | 2020-07-11 |
| The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics (NCT04252495) | Idorsia Pharmaceuticals Ltd. | 2020-06-26 |
| A Study in Healthy Male Subjects to Investigate the Effect of Famotidine and Efavirenz on the Way the Body Takes up, Distributes, and Gets Rid of Daridorexant. (NCT04390334) | Idorsia Pharmaceuticals Ltd. | 2020-05-13 |
| To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and Women (NCT04281342) | Idorsia Pharmaceuticals Ltd. | 2020-01-14 |
| A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease. (NCT04162366) | Idorsia Pharmaceuticals Ltd. | 2020-01-01 |
| A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects (NCT04183686) | Idorsia Pharmaceuticals Ltd. | 2019-11-25 |
| Study of the Way the Body Takes up, Distributes, and Gets Rid of ACT-541468 in Subjects With Abnormal Kidney Function Compared to Healthy Subjects (NCT04024332) | Idorsia Pharmaceuticals Ltd. | 2019-09-24 |
| Natural History Study for Pediatric Patients With Early Onset of Either GM1 Gangliosidosis, GM2 Gangliosidoses, or Gaucher Disease Type 2 (NCT04470713) | Idorsia Pharmaceuticals Ltd. | 2019-07-31 |
| A Study to Evaluate ID-085 in People With Mild, Moderate, and Severe Kidney Disease (NCT03913000) | Idorsia Pharmaceuticals Ltd. | 2019-04-29 |
| A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female Subjects (NCT03907215) | Idorsia Pharmaceuticals Ltd. | 2019-04-09 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects (NCT03869320) | Idorsia Pharmaceuticals Ltd. | 2019-03-25 |
| A Clinical Study to Assess Next-day Driving Performance Following Administration of ACT-541468 in Middle-aged and Elderly Subjects (NCT03892902) | Idorsia Pharmaceuticals Ltd. | 2019-03-25 |
| A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep Apnea (NCT03765294) | Idorsia Pharmaceuticals Ltd. | 2019-03-14 |
| A Clinical Study to Investigate the Food Effect on the Pharmacokinetics of ACT-541468 in Healthy Male Subjects (NCT03799978) | Idorsia Pharmaceuticals Ltd. | 2019-03-09 |
| A Study in Healthy Subjects to Investigate Whether Administration of Lucerastat Can Affect Normal Heart Function (NCT03832452) | Idorsia Pharmaceuticals Ltd. | 2019-02-14 |
| Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain (NCT03585270) | Idorsia Pharmaceuticals Ltd. | 2019-02-03 |
| A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease (NCT03737214) | Idorsia Pharmaceuticals Ltd. | 2018-12-18 |
| A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary Disease (NCT03646864) | Idorsia Pharmaceuticals Ltd. | 2018-11-15 |
| A Study to Evaluate the Effect of ACT-774312 in Subjects With Bilateral Nasal Polyposis (NCT03688555) | Idorsia Pharmaceuticals Ltd. | 2018-10-19 |
| Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep (NCT03679884) | Idorsia Pharmaceuticals Ltd. | 2018-10-09 |
| A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart Function (NCT03657446) | Idorsia Pharmaceuticals Ltd. | 2018-09-18 |
| Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users (NCT03657355) | Idorsia Pharmaceuticals Ltd. | 2018-09-07 |
| A Study to Investigate the Drug-drug Interactions Between ACT-541468 and Ethanol in Healthy Subjects (NCT03609775) | Idorsia Pharmaceuticals Ltd. | 2018-08-28 |
| A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of Clazosentan (NCT03596294) | Idorsia Pharmaceuticals Ltd. | 2018-07-19 |
| A Study to Evaluate How Aprocitentan is Safe and How it is Absorbed and Broken Down in the Body of Japanese and Caucasian Subjects (NCT03586570) | Idorsia Pharmaceuticals Ltd. | 2018-07-17 |
| Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease (NCT03425539) | Idorsia Pharmaceuticals Ltd. | 2018-06-21 |
| A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety (NCT03541174) | Idorsia Pharmaceuticals Ltd. | 2018-06-18 |
| Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder (NCT03545191) | Idorsia Pharmaceuticals Ltd. | 2018-06-04 |
| Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep (NCT03575104) | Idorsia Pharmaceuticals Ltd. | 2018-05-29 |
| A Study to Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment (NCT03713242) | Idorsia Pharmaceuticals Ltd. | 2018-02-26 |
| A Study to Evaluate if ID-085 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects (NCT03372629) | Idorsia Pharmaceuticals Ltd. | 2018-01-12 |
| Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects (NCT03380455) | Idorsia Pharmaceuticals Ltd. | 2018-01-09 |
| Pharmacokinetic Interaction Between Midazolam and ID-082 in Healthy Subjects (NCT03363984) | Idorsia Pharmaceuticals Ltd. | 2017-11-27 |
| A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin (NCT03339752) | Idorsia Pharmaceuticals Ltd. | 2017-10-30 |
| A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients (NCT03239691) | Idorsia Pharmaceuticals Ltd. | 2017-10-06 |