| Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery (NCT05624151) | Ain Shams University | 2022-11-25 |
| Comparison of JW-100 and EUCRISA for the Treatment of Atopic Dermatitis (NCT05016284) | Applied Biology, Inc. | 2022-11-24 |
| A Clinical Trial to Evaluate the Efficacy and Safety of CKD-391 and CKD-331 in Patients With Primary Hypercholesterolemia (NCT05657574) | Chong Kun Dang Pharmaceutical | 2022-11-24 |
| Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del (NCT05331183) | Vertex Pharmaceuticals Incorporated | 2022-11-23 |
| Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease (NCT05517421) | Immunovant Sciences GmbH | 2022-11-23 |
| A Study to Evaluate the Efficacy, Safety, and Immunogenicity of SARS-CoV-2 Variant (BA.4 /5) mRNA Vaccine (NCT05636319) | Suzhou Abogen Biosciences Co., Ltd. | 2022-11-23 |
| A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Alendronic Acid on Alveolar Bone Remodeling After Tooth Extraction (NCT05602493) | Xeolas Pharmaceuticals Limited | 2022-11-22 |
| Impact of a Treatment With Angiotensin Receptor Blocker on Outcome After Acute Kidney Injury in Patients Discharged From the ICU. (NCT05272878) | Assistance Publique - Hôpitaux de Paris | 2022-11-22 |
| Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement (NCT05641064) | University Hospital Dubrava | 2022-11-22 |
| A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body (NCT05568095) | Arcus Biosciences, Inc. | 2022-11-21 |
| A Study to Assess Safety, Tolerability and Efficacy of Garetosmab Versus Placebo Administered Intravenously (IV) in Adult Participants With Fibrodysplasia Ossificans Progressiva (FOP) (NCT05394116) | Regeneron Pharmaceuticals | 2022-11-21 |
| A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia (NCT05610280) | Ionis Pharmaceuticals, Inc. | 2022-11-21 |
| Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults (NCT05157685) | Centre Hospitalier Intercommunal Creteil | 2022-11-21 |
| A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (NCT05456191) | Novartis Pharmaceuticals | 2022-11-21 |
| Hulio Interchangeability to Humira®, Comparing Pharmacokinetics, Efficacy, Safety and Immunogenicity (NCT05637515) | Biocon Biologics Inc. | 2022-11-21 |
| Psoriatic Arthritis Study of Izokibep (NCT05623345) | ACELYRIN Inc. | 2022-11-21 |
| Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer (NCT05474846) | M.D. Anderson Cancer Center | 2022-11-21 |
| TNT of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer (NCT05646511) | National Cancer Center Hospital East | 2022-11-21 |
| Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III) (NCT05658510) | BioXcel Therapeutics Inc | 2022-11-21 |
| Fibrinogen Early In Severe Trauma StudY II (NCT05449834) | Australian and New Zealand Intensive Care Research Centre | 2022-11-21 |
| Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (NCT05468320) | Sanofi | 2022-11-21 |
| Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis (NCT05556096) | Alexion Pharmaceuticals, Inc. | 2022-11-21 |
| Laparoscopic Gastrectomy With D2 Lymphadenectomy Combined With Hyperthermic Intraperitoneal Chemotherapy (HIPEC) or Not (NCT05871099) | The Affiliated Hospital of Qingdao University | 2022-11-20 |
| PE-Bacon for Late Complications of Chronic Radiation-induced Rectal Injury (NCT05607927) | Sixth Affiliated Hospital, Sun Yat-sen University | 2022-11-20 |
| A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (NCT05614063) | Xenon Pharmaceuticals Inc. | 2022-11-18 |
| Pharmacogenomics of antiVEGF in Patients With Age-Associated Macular Degeneration (AMD) (NCT06952452) | Parc de Salut Mar | 2022-11-18 |
| A Trial to Determine the Efficacy and Safety of Presendin in IIH (NCT05347147) | Invex Therapeutics Ltd. | 2022-11-18 |
| Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic Conjunctivitis (NCT05591755) | Bausch & Lomb Incorporated | 2022-11-18 |
| A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES) (NCT05603754) | Biosplice Therapeutics, Inc. | 2022-11-18 |
| To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC (NCT05468489) | Shanghai Henlius Biotech | 2022-11-18 |
| PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study (NCT05276557) | ARJ Medical, Inc. | 2022-11-17 |
| Effects of Triptorelin Pamoate 6-month When Given to Adult Chinese Participants With Advanced Cancer in the Prostate (NCT05590793) | Ipsen | 2022-11-17 |
| Teen Driving Translation Study (NIH) (NCT05696353) | Ginger Yang | 2022-11-17 |
| A Phase 3 Study of F14 for Management of Pain Following Total Knee Replacement (NCT05603832) | Arthritis Innovation Corporation | 2022-11-17 |
| Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement (NCT05283980) | Beth Israel Deaconess Medical Center | 2022-11-17 |
| A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs) (NCT05321082) | Boehringer Ingelheim | 2022-11-16 |
| Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma (NCT05256225) | National Cancer Institute (NCI) | 2022-11-16 |
| Evaluation of Efficacy and Safety of ATB-1011+ATB-1012 Co-administration for Essential Hypertension and Type II Diabetes (NCT05573477) | Autotelicbio | 2022-11-16 |
| A Safety, Tolerability, and Efficacy Study of Veligrotug (VRDN 001) in Participants With Thyroid Eye Disease (TED) (NCT05176639) | Viridian Therapeutics, Inc. | 2022-11-16 |
| Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years (NCT05643534) | Ardelyx | 2022-11-15 |
| ProUrokinase for Mild Ischemic Cerebrovascular Events (PUMICE) (NCT05507645) | Beijing Tiantan Hospital | 2022-11-15 |
| Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis (NCT05511766) | Tanta University | 2022-11-15 |
| Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation (NCT05535738) | Wei-Che Ko | 2022-11-15 |
| Study Comparing Estradiol Vaginal Inserts 4mcg To IMVEXXY ® (Estradiol Vaginal Inerts 4 mcg) In The Treatment Of Dyspareunia in Women With Vulvur and Vaginal Atrophy (NCT05617820) | Teva Pharmaceuticals USA | 2022-11-15 |
| Efficacy and Safety of Zihua Wenfei Granules in Treatment of Postinfectious Cough (Wind-cold Invading Lungs Syndrome) (NCT05764668) | DoCare Pharmaceutial Technology Co.,Ltd | 2022-11-15 |
| A Clinical Study to Compare the Efficacy and Safety of HLX10 in Combination With HLX04 Versus Sorafenib as the First-line Treatment in Patients With Locally Advanced or Metastatic HCC (NCT04465734) | Shanghai Henlius Biotech | 2022-11-15 |
| Carotid Artery Stenting During Endovascular Treatment of Acute Stroke (NCT06511089) | University Medical Center Groningen | 2022-11-15 |
| A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita (NCT05643872) | Palvella Therapeutics, Inc. | 2022-11-15 |
| A Study of IBI362 in Participants With Obesity or Overweight (NCT05607680) | Innovent Biologics (Suzhou) Co. Ltd. | 2022-11-14 |
| A Comparative Study on Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl for Optimal Dose to be Used in Elderly Patients Undergoing Day Case Lower Abdominal and Urologic Surgeries. (NCT05726968) | Cairo University | 2022-11-14 |
| Efficacy and Safety of Subcutaneous Belimumab or Placebo in Addition of Rituximab in Persistent or Chronic Immune Thrombocytopenia (NCT05338190) | Assistance Publique - Hôpitaux de Paris | 2022-11-14 |
| A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension (NCT05167825) | Janssen Pharmaceutical K.K. | 2022-11-14 |
| Study of RAY1216 Tablets Compared With Placebo in Patients With Mild to Moderate COVID-19 (NCT05620160) | Guangdong Raynovent Biotech Co., Ltd | 2022-11-12 |
| Neoadjuvant Therapy of Sintilimab Combined With Chemotherapy for Resectable Squamous Cell NSCLC（neoSCORE Ⅱ） (NCT05429463) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-11-11 |
| Induction Chemotherapy Followed by IMRT or Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma (NCT05527470) | Wei Jiang | 2022-11-11 |
| Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-Syndrome (NCT05638633) | Wuerzburg University Hospital | 2022-11-11 |
| the Efficacy and Safety of Rulonilimab in Combination With Lenvatinib in Hepatocellular Carcinoma (NCT05408221) | Shandong New Time Pharmaceutical Co., LTD | 2022-11-11 |
| Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) Compared With Egg-Based Quadrivalent Influenza Vaccine (IIV4) in Participants Aged 3 to 8 Years (NCT05513391) | Sanofi Pasteur, a Sanofi Company | 2022-11-10 |
| Phase 2/Phase 3 Study To Evaluate The Efficacy And Safety Of Ramatroban Along With The Standard Of Care In Subjects Hospitalized For COVID Pneumonia (NCT05706454) | KARE Biosciences | 2022-11-10 |
| NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-Iberdomide (NCT05558319) | PETHEMA Foundation | 2022-11-10 |
| Intranasal Versus Nebulized Midazolam in Behaviuor Modification of Preschool Children Undergoing Dental Treatment (NCT05883150) | Nourhan M.Aly | 2022-11-10 |
| Efficacy of Traditional Chinese Medicine on Ameliorating IVF-ET Outcomes of Diminished Ovarian Reserve Patients (NCT05577455) | Peking University Third Hospital | 2022-11-10 |
| A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant (NCT05623020) | Pfizer | 2022-11-10 |
| Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis (NCT05583227) | AstraZeneca | 2022-11-10 |
| Oral Epalrestat Therapy in Pediatric Subjects With PMM2-CDG (NCT04925960) | Maggie's Pearl, LLC | 2022-11-10 |
| Effect of Dipeptidyl Peptidase- 4 Inhibitors on Non-Alcoholic Steatohepatitis and Type 1 Diabetes (NCT06348706) | Ain Shams University | 2022-11-10 |
| The Possible Protective Role of Ketotifen Against Oxaliplatin Induced Peripheral Neuropathy (NCT05624138) | Tanta University | 2022-11-09 |
| AK112 in Advanced Non-Small Cell Lung Cancer (NCT05499390) | Akeso | 2022-11-09 |
| A Trial of Absorbable Regenerated Oxidized Cellulose for Surgical Hemostasis) (NCT07764055) | Medprin Regenerative Medical Technologies Co., Ltd. | 2022-11-09 |
| Effectiveness of Cannabinoids on Appetite in Scleroderma (NCT05416697) | Khon Kaen University | 2022-11-09 |
| A Study to Evaluate the Efficacy and Safety of BR1015 Combination Therapy (NCT05878561) | Boryung Pharmaceutical Co., Ltd | 2022-11-09 |
| Budesonide Prophylaxis for Engraftment Syndrome After Hematopoietic Cell Transplantation (NCT05509933) | Henry Ford Health System | 2022-11-09 |
| Phase II/III Study of the AVX/COVID-12 Vaccine Against COVID-19 Applied as a Booster. (NCT05710783) | Laboratorio Avi-Mex, S.A. de C.V. | 2022-11-09 |
| A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria (NCT05457283) | Bayer | 2022-11-08 |
| Tezepelumab on Airway Structure and Function in Patients With Uncontrolled Moderate-to-severe Asthma (NCT05280418) | McMaster University | 2022-11-08 |
| A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy (NCT05444257) | Vertex Pharmaceuticals Incorporated | 2022-11-08 |
| A Study of Jincaopian Tablets on Chronic Pelvic Pain After Pelvic Inflammatory Disease (NCT05970783) | Beijing Konruns Pharmaceutical Co., Ltd. | 2022-11-08 |
| Evaluating the Efficacy and Safety of QL0911 in the Prevention of Chemotherapy- Induced Thrombocytopenia (NCT05554913) | Qilu Pharmaceutical Co., Ltd. | 2022-11-08 |
| An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia (NCT05643170) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2022-11-08 |
| Study to Assess the Effects of Cabotegravir (CAB) and Rilpivirine (RPV) Long-Acting (LA) Injections Following Sub-cutaneous (SC) Administration Compared With Intramuscular (IM) Administration in Adult Participants Living With Human Immunodeficiency Virus (HIV-1) Infection in the FLAIR Study (NCT05896748) | ViiV Healthcare | 2022-11-08 |
| The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD (NCT05374291) | University Medical Center Groningen | 2022-11-08 |
| Clinical and Radiographic Evaluation of Natural Bovine Bone With Hyaluronic Acid on Osseointegration of Immediate Implant. (NCT07199725) | Suez Canal University | 2022-11-08 |
| Repeated GON Injections in CCH (NCT05324748) | Leiden University Medical Center | 2022-11-07 |
| Trial Assessing the Immunogenicity and Safety of Two Influenza Vaccine Strategies Among Severe Obese Adult Patients (NCT05409612) | Assistance Publique - Hôpitaux de Paris | 2022-11-07 |
| Open-label Extension for Phase 3 Clinical Trials of Simufilam (NCT05575076) | Cassava Sciences, Inc. | 2022-11-07 |
| Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in Patients With Vascular Ehlers-Danlos Syndrome (NCT05432466) | Acer Therapeutics Inc. | 2022-11-07 |
| To Compare Pharmacokinetics, Efficacy, and Safety of CT-P17 With Humira in Patients With Moderate to Severe Chronic Plaque Psoriasis (NCT05495568) | Celltrion | 2022-11-07 |
| Study of the Efficacy and Safety of Broncho-munal®, Capsules, 7 mg for the Treatment of Acute Uncomplicated Respiratory Tract Infections (NCT05588804) | Sandoz | 2022-11-07 |
| Safety and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults 50 Years of Age or Older (V116-010, STRIDE-10) (NCT05569954) | Merck Sharp & Dohme LLC | 2022-11-07 |
| A Trial Evaluate the Immunogenicity and Safety of Recombinant COVID-19 Omicron-Delta Variant Vaccine (CHO Cell) (NCT05616754) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2022-11-07 |
| Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease (NCT05517447) | Immunovant Sciences GmbH | 2022-11-06 |
| Study of Obeldesivir in Participants With COVID-19 Who Have a High Risk of Developing Serious or Severe Illness (NCT05603143) | Gilead Sciences | 2022-11-05 |
| Phase III Clinical Trial of 13-valent Pneumococcal Conjugate Vaccine (Multivalent Conjugate) in Infants (NCT05759520) | Fosun Adgenvax Biopharmaceutical Co.,Ltd. | 2022-11-04 |
| Clinical Trial to Evaluate the Immunogenicity of an Adjuvanted Influenza Vaccine Among HCP (NCT06054269) | Centers for Disease Control and Prevention | 2022-11-04 |
| Recombinant COVID-19 Vaccine (CHO Cell, NVSI-06-09) Phase III Clinical Trial (NCT05599516) | National Vaccine and Serum Institute, China | 2022-11-04 |
| Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer (NCT05448547) | Sven Löffeler | 2022-11-04 |
| Comparative Study of Hexvix Blue Light Cystoscopy and White Light Cystoscopy in the Detection of Bladder Cancer (NCT05600322) | Photocure | 2022-11-03 |
| Asunercept for the Treatment of Patients With Moderate to Severe COVID-19 Disease (NCT05639192) | Apogenix GmbH | 2022-11-03 |
| Perampanel in Focal Status Epilepticus (NCT04309721) | Assistance Publique - Hôpitaux de Paris | 2022-11-02 |
| Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial - Follow Up Long Term Extension (IMPAHCT-FUL) (NCT05557942) | Aerovate Therapeutics | 2022-11-02 |