| CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG) (NCT05681351) | Ionis Pharmaceuticals, Inc. | 2022-12-13 |
| Latino Semaglutide Study (NCT05087342) | Loma Linda University | 2022-12-13 |
| Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen (NCT05624450) | AstraZeneca | 2022-12-13 |
| A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28) (NCT05668988) | Dizal Pharmaceuticals | 2022-12-13 |
| Xian-Hua-Cha for Relieving Hyperlipidemia With Obesity (NCT05632068) | Chang Gung Memorial Hospital | 2022-12-13 |
| A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus (NCT05648500) | Viatris Innovation GmbH | 2022-12-13 |
| Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE) (NCT05730699) | Biocad | 2022-12-12 |
| Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population (NCT05724446) | Salvat | 2022-12-12 |
| Impact of Peri-operative tEstosterone Levels on oNcological and Functional Outcomes in RadiCal prostatEctomy (NCT04833426) | Canisius-Wilhelmina Hospital | 2022-12-12 |
| Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19 (NCT05619653) | Valentina Puentmann | 2022-12-12 |
| Safety Study of a Vaccine to Help Protect Against Lyme Disease in Healthy Children (NCT05634811) | Pfizer | 2022-12-12 |
| Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp (NCT05662202) | Biofrontera Inc. | 2022-12-12 |
| Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63) (NCT05633654) | Gilead Sciences | 2022-12-12 |
| Icaritin Soft Capsule Versus Huachansu Tablet in the First-line Treatment of Unresectable Hepatocellular Carcinoma With Poor Conditions and Biomarker Enrichment (Biomarker Enrichment Study of Poor Prognosis HCC Patients, BESTPOP) (NCT05594927) | Beijing Shenogen Biomedical Co., Ltd | 2022-12-12 |
| Immunogenicity and Safety of Vaccine Against Tetanus and Diphtheria. (NCT05480462) | IBSS Biomed S.A. | 2022-12-12 |
| Didroxyprogesterone Promotes Natural Pregnancy in Infertile Patients With Endometriosis (NCT05467852) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2022-12-10 |
| A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B (NCT05611801) | Pfizer | 2022-12-09 |
| An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib (NCT05513001) | Novartis Pharmaceuticals | 2022-12-09 |
| DLBS2411 Treatment For Functional Dyspepsia (NCT05248802) | Dexa Medica Group | 2022-12-09 |
| A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females (NCT05584332) | Shanghai Bovax Biotechnology Co., Ltd. | 2022-12-09 |
| A Study to Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC) (NCT05644665) | Bristol-Myers Squibb | 2022-12-09 |
| Efficacy and Safety in Chinese Patients with Immunoglobulin a Nephropathy (IgAN) Who Have Completed Study Nef-301 (NCT05534919) | Everest Medicines (Singapore) Pte. Ltd. | 2022-12-09 |
| Immunogenicity and Safety Study of Heterologous Booster Vaccination of a SARS-CoV-2 Recombinant Protein Nanoparticle Vaccine(GBP510) Adjuvanted with AS03 in Adults Aged 18 Years and Older (NCT05501522) | SK Bioscience Co., Ltd. | 2022-12-09 |
| Enteral Resuscitation Nepal (NCT05559489) | Nepal Health Research Council | 2022-12-08 |
| A Study of QL1706 Combined With Platinum-containing Chemotherapy in Adjuvant Treatment of Stage II-IIIB Non-small Cell Lung Cancer After Complete Surgical Resection. (NCT05487391) | Qilu Pharmaceutical Co., Ltd. | 2022-12-08 |
| A Study to Assess the Safety and Efficacy of Vatiquinone in Participants With Friedreich Ataxia (NCT05515536) | PTC Therapeutics | 2022-12-08 |
| Integrating Financial Coaching and Smoking Cessation Coaching (NCT05154669) | NYU Langone Health | 2022-12-08 |
| Improving HIV-1 Control in Africa with Long Acting Antiretrovirals (NCT05546242) | MRC/UVRI and LSHTM Uganda Research Unit | 2022-12-08 |
| Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1) (NCT05501886) | Celcuity Inc | 2022-12-08 |
| Efficacy and Safety of Brodalumab in Adolescents From 12 to 17 Years of Age With Moderate-to-severe Plaque Psoriasis (NCT04305327) | LEO Pharma | 2022-12-07 |
| Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 1) (NCT05630807) | GlaxoSmithKline | 2022-12-07 |
| Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer (NCT05646316) | NRG Oncology | 2022-12-07 |
| ADC189 Tablets on Influenza A Virus Infection/Influenza B Virus Infection (NCT06342921) | Jiaxing AnDiCon Biotech Co.,Ltd | 2022-12-07 |
| A Two-Stage Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics and Immunogenicity of Various Doses of Levilimab When Administered Intravenously and Subcutaneously to Healthy Subjects and Subjects With Active Rheumatoid Arthritis (NCT05800327) | Biocad | 2022-12-07 |
| Long-term Aspirin Therapy as a Predictor of Decreased Susceptibility to SARS-CoV-2 Infection in Aspirin-Exacerbated Respiratory Disease (NCT05797597) | Lucyna Mastalerz | 2022-12-07 |
| Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study. (NCT05439005) | Institut Curie | 2022-12-07 |
| Incidence of Caesarean Scar Defect in Cases of Cesarean Section With and Without Bladder Flap Dissection (NCT06503627) | Alexandria University | 2022-12-07 |
| Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure (NCT05652322) | Jan Kochanowski University | 2022-12-07 |
| Colchicine Use for Primary Prevention of Coronary Artery Disease (NCT05175274) | Qingdao Central Hospital | 2022-12-06 |
| Study of B013 and Nab-Paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer (NCT05555706) | Shanghai Jiaolian Drug Research and Development Co., Ltd | 2022-12-06 |
| A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain (NCT05658874) | Jocelyn Fitzgerald | 2022-12-06 |
| Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B (B-Well 2) (NCT05630820) | GlaxoSmithKline | 2022-12-06 |
| Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial (NCT05047198) | Ottawa Heart Institute Research Corporation | 2022-12-06 |
| A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy (NCT05550532) | Janssen Research & Development, LLC | 2022-12-06 |
| Role of Vit-D Supplementation on BioNTech, Pfizer Vaccine Side Effect and Immunoglobulin G Response (NCT05851313) | Sulaimani Polytechnic University | 2022-12-05 |
| A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke (NCT05643573) | Bayer | 2022-12-05 |
| A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (NCT05600777) | Bellus Health Inc. - a GSK company | 2022-12-05 |
| The Role of Colchicine in Reducing The Rate of Myocardial Reperfusion Injury (NCT05734612) | Indonesia University | 2022-12-04 |
| Endovascular Thrombectomy With and Without Intravenous Thrombolysis in Extended Time Window (NCT05634382) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-12-03 |
| Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection. (NCT06220344) | HITEC-Institute of Medical Sciences | 2022-12-02 |
| Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid Arthritis (NCT05480878) | Tanta University | 2022-12-02 |
| Study of Efficacy and Safety of AIN457/Secukinumab in Patients With Rotator Cuff Tendinopathy (NCT05569174) | Novartis Pharmaceuticals | 2022-12-02 |
| Romiplostim Plus Dexamethasone vs Dexamethasone in Patients With Newly Diagnosed Primary Immune Thrombocytopenia (NCT05325593) | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 2022-12-02 |
| Bringing Optimised COVID-19 Vaccine Schedules To ImmunoCompromised Populations (BOOST-IC): an Adaptive Randomised Controlled Clinical Trial (NCT05556720) | Monash University | 2022-12-01 |
| Dapagliflozin Effect on Rheumatic Mitral Stenosis (NCT05618223) | Universitas Sebelas Maret | 2022-12-01 |
| [18F]PI-2620 Phase 3 Histopathological Study (NCT05641688) | Lantheus Biosciences Ltd. | 2022-12-01 |
| Phase 3 Study of KP-100LI in Subjects With Vocal Fold Scar (NCT05627648) | Kringle Pharma, Inc. | 2022-12-01 |
| Risk of Hypoglycemia in the Transition From Inpatient to Outpatient Setting. Comparative Study of Basal-bolus Insulin Versus Basal Insulin Plus GLP-1 Analogue (NCT05767255) | Hospital Universitario San Ignacio | 2022-12-01 |
| Xian-Lian-Jie-Du Optimization Decoction As an Adjuvant Treatment for Prevention of Recurrence of Colon Cancer (NCT05709249) | Jiangsu Famous Medical Technology Co., Ltd. | 2022-12-01 |
| Observation on the Efficacy and Mechanism of SLIT With Dust Mite Allergen for PAR (NCT05570383) | People's Hospital of Anshun City of Guizhou Province | 2022-12-01 |
| Using Acetylcysteine and Vitamin E With Psoriasis Vulgaris (NCT05906498) | Badr University | 2022-12-01 |
| Magnesium Treating Subarachnoid Hemorrhage Vasospasm (NCT04613960) | General Committee of Teaching Hospitals and Institutes, Egypt | 2022-12-01 |
| Opioid Sparing Anesthesia in Patients With Liver Cirrhosis Undergoing Liver Resection (NCT05674877) | Cairo University | 2022-12-01 |
| Interleukin-2 on Active Dermatomyositis (NCT05495321) | Peking University People's Hospital | 2022-12-01 |
| Pirfenidone in Adult Hospitalized Patients With COVID-19 (NCT05713292) | Capital Medical University | 2022-12-01 |
| Evaluating the Safety and Efficacy of AD17002 Intranasal Spray in Treating Participants With Mild to Moderate COVID-19 (NCT05541510) | Advagene Biopharma Co. Ltd. | 2022-12-01 |
| Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain (NCT05608733) | Universidad de Antioquia | 2022-12-01 |
| Effect of Melatonin in Pediatric Hemodialysis Patients (NCT05570526) | Ain Shams University | 2022-12-01 |
| To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in Healthy Children Aged From 24mons-15yrs (NCT05613127) | Boryung Biopharma Co., Ltd. | 2022-12-01 |
| Study of Early Stage Endometrial Cancer Based on Molecular Classification and Traditional Risk Stratification to Guide Adjuvant Radiotherapy Decisions (NCT05524389) | Peking Union Medical College Hospital | 2022-12-01 |
| Efficacy and Safety Evaluation for the Treatment of HDM Induced Allergic Asthma and Rhinitis/Rhinoconjunctivitis (NCT05400811) | Inmunotek S.L. | 2022-12-01 |
| A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) Tranquillo (NCT05583526) | Pfizer | 2022-12-01 |
| Effects of Curcumin on Inflammation and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study (NCT05627843) | Ain Shams University | 2022-12-01 |
| Role of Combined Therapy of Propranolol and Gabapentin in Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury (NCT05427474) | Zagazig University | 2022-12-01 |
| VCMX, PRF and SCTG Treatment in the Gingival Recessions (NCT07345520) | Bulent Ecevit University | 2022-12-01 |
| Shaping Care Home COVID-19 Testing Policy (NCT05639205) | University College, London | 2022-12-01 |
| CBP-201 in Adolescent and Adult Patients With Moderate-to-severe Atopic Dermatitis (NCT05614817) | Connect Biopharm LLC | 2022-12-01 |
| The Phase Ⅱ/Ⅲ Trial of LYB001 (NCT05602558) | Yantai Patronus Biotech Co., Ltd. | 2022-12-01 |
| Safety and Immunogenicity of Inactivated Heterologous Booster Vaccination (NCT05545683) | Centro de Estudios en Infectogía Pediatrica | 2022-12-01 |
| Effects of Vaginal Oxytocin Gel on Vaginal Cytologic Parameters in Postmenopausal Woman (NCT05627791) | Department of Medical Services Ministry of Public Health of Thailand | 2022-11-30 |
| A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Participants With Guillain-Barré Syndrome (GBS) (NCT05494619) | Hoffmann-La Roche | 2022-11-30 |
| A Study of Navicixizumab in Patients With Platinum Resistant Ovarian Cancer (NCT05043402) | OncXerna Theraputics, Inc. | 2022-11-30 |
| Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension (NCT05678621) | Monash University | 2022-11-30 |
| A Study to Evaluate the Safety and Immunogenicity of Ad5-vector Based Vaccine Against Coronavirus Variants in Adults (≥18 Years) Immunized With 2 Doses of mRNA Vaccines Plus One Dose of Booster AZD1222 Vaccine (NCT05442684) | CanSino Biologics Inc. | 2022-11-30 |
| Evaluating the Efficacy of NTI164 in Young People With Autism Spectrum Disorder (NCT05626959) | Fenix Innovation Group | 2022-11-30 |
| An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM) (NCT05667493) | Ionis Pharmaceuticals, Inc. | 2022-11-30 |
| Active-control Randomized Trial Comparing 4-factor Prothrombin Complex Concentrate With Frozen Plasma in Cardiac Surgery (NCT05523297) | Octapharma | 2022-11-30 |
| Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer (NCT05522660) | ETOP IBCSG Partners Foundation | 2022-11-30 |
| Fluorocholine PET/CT Basket Trial (NCT04150458) | Sir Mortimer B. Davis - Jewish General Hospital | 2022-11-30 |
| 3TR (Taxonomy, Treatment, Targets and Remission) Systemic Lupus Erithematosus Study Protocol (NCT05458622) | University Hospital, Brest | 2022-11-29 |
| Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD) (NCT04939935) | The University of Queensland | 2022-11-29 |
| Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple Sclerosis (NCT05809414) | Hospital San Carlos, Madrid | 2022-11-28 |
| Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis (NCT05428488) | University Hospital, Montpellier | 2022-11-28 |
| Multi-center Trial of Ferric Derisomaltose in Children 0 to <18 Years of Age With Iron Deficiency Anemia (NCT05179226) | Pharmacosmos A/S | 2022-11-28 |
| Erector Spinae Plane Block Versus Caudal Epidural Analgesia (NCT06815094) | National Cancer Institute, Egypt | 2022-11-28 |
| A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03) (NCT05629585) | AstraZeneca | 2022-11-28 |
| A Study to Evaluate Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis (NCT05601882) | AbbVie | 2022-11-28 |
| Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal (NCT05470205) | Thomas Jefferson University | 2022-11-28 |
| Prophylactic Antibiotic Use in Transarterial Chemoembolization for Hepatocellular Carcinoma (NCT05654896) | Nadeem Iqbal | 2022-11-26 |
| SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19 (NCT05629962) | Atea Pharmaceuticals, Inc. | 2022-11-25 |