| Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma (NCT06647953) | Children's Oncology Group | 2025-03-21 |
| Methadone to Treat Painful Chemotherapy Induced Peripheral Neuropathy (NCT05786599) | University of British Columbia | 2025-03-21 |
| A Study to Evaluate the Efficacy and Safety of Subcutaneous Tildrakizumab in Subjects With Moderate to Severe Genital Psoriasis. (NCT06611163) | Sun Pharmaceutical Industries Limited | 2025-03-21 |
| TQC2731 Clinical Trial for the Treatment of Severe Asthma With Injection (NCT06829784) | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | 2025-03-21 |
| A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (NCT06840392) | Novartis Pharmaceuticals | 2025-03-20 |
| Efficacy, Safety, Pharmacokinetics of ICP-488 in Patients With Moderate to Severe Plaque Psoriasis (NCT06842199) | Beijing InnoCare Pharma Tech Co., Ltd. | 2025-03-20 |
| Deep Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Patients Undergoing Primary Repair of Septal Defects Via Median Sternotomy (NCT06873906) | Ain Shams University | 2025-03-20 |
| Phase 3 Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease (NCT06925594) | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 2025-03-20 |
| Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate: Exploring Its Role in Optimizing Surgical Outcomes (NCT07733167) | Benha University | 2025-03-20 |
| Effect of Semaglutide in Patients With Psoriasis and Obesity (NCT06937060) | The University of Hong Kong | 2025-03-20 |
| Walking With Overground Robotic Exoskeletons to Improve Arrousal in Individuals With Disorders of Consciousness (NCT06780280) | Craig Hospital | 2025-03-20 |
| A Study of Navenibart in Participants With Hereditary Angioedema (NCT06842823) | Astria Therapeutics, Inc. | 2025-03-20 |
| Phase II/III Seamless Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Treatment of Seasonal Allergic Rhinitis (NCT06846385) | Shanghai Mabgeek Biotech.Co.Ltd | 2025-03-20 |
| Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01) (NCT06819007) | Daiichi Sankyo | 2025-03-19 |
| Interleukin-2 for Refractory Chronic Spontaneous Urticaria (NCT06924762) | Second Xiangya Hospital of Central South University | 2025-03-19 |
| Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea (NCT06533865) | Massachusetts General Hospital | 2025-03-19 |
| A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006) (NCT06883305) | AstraZeneca | 2025-03-18 |
| A Pivotal Study of N-Acetyl-L-Leucine on Ataxia-Telangiectasia (A-T) (NCT06673056) | IntraBio Inc | 2025-03-18 |
| Safety and Efficacy Evaluation of NH002 as a Contrast Agent in Subjects Undergoing Cardiac Echocardiography (NCT06815627) | Trust Bio-sonics, Inc. | 2025-03-18 |
| Pegylated Liposomal Doxorubicin Plus Adebrelimab With or Without Mirabegron in Relapsed Ovarian Cancer (NCT06791460) | Obstetrics & Gynecology Hospital of Fudan University | 2025-03-18 |
| An Open-Label Study of Azetukalner in Major Depressive Disorder (NCT06922110) | Xenon Pharmaceuticals Inc. | 2025-03-18 |
| Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight (NCT06858878) | Amgen | 2025-03-17 |
| A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease (NCT06819878) | Hoffmann-La Roche | 2025-03-17 |
| Study of IBI354 Versus Investigator's Choice of Chemotherapy in Patients With Platinum-resistant Ovarian, Primary Peritoneal, or Fallopian Tube Cancer (NCT06834672) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-03-17 |
| Phase III Clinical Study of VC004 in Patients With Localized Advanced/ Metastatic Solid Tumors (NCT06658353) | Jiangsu vcare pharmaceutical technology co., LTD | 2025-03-17 |
| A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011) (NCT06841354) | Merck Sharp & Dohme LLC | 2025-03-16 |
| A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty (NCT06825416) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2025-03-16 |
| Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children. (NCT06389110) | Laboratorios Sophia S.A de C.V. | 2025-03-15 |
| Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers (NCT06910579) | British University In Egypt | 2025-03-15 |
| Jianzhong Qushi in Chronic RRI (NCT06837597) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-03-15 |
| Evaluation of Early Administration of Levetiracetam in the Prevention and Treatment Encephalopathy in Septic Shock: Randomized, Double-blind, Placebo-controlled Trial (NCT06851078) | Assistance Publique - Hôpitaux de Paris | 2025-03-15 |
| Ripertamab for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (NCT06858722) | Zhongming Qiu | 2025-03-15 |
| Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors (NCT06493552) | Vasgene Therapeutics, Inc | 2025-03-15 |
| Thrombolysis in Factor Xa-inhibitors Trial (NCT06878066) | Guri Hagberg | 2025-03-14 |
| Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin (NCT06677060) | AstraZeneca | 2025-03-14 |
| Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer (NCT06661720) | Alliance for Clinical Trials in Oncology | 2025-03-14 |
| Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab (NCT06869785) | Novartis Pharmaceuticals | 2025-03-13 |
| A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer (NCT06764485) | Celgene | 2025-03-13 |
| Evaluation of the Anti-cavity Efficacy of Three Dentifrices Using an Intra-oral Enamel Demineralization - Remineralization In-Situ Model (NCT06732518) | Colgate Palmolive | 2025-03-13 |
| Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention (NCT06748625) | LuciLab | 2025-03-13 |
| A Study of SHR-A1811 in Subjects With Ovarian Cancer (NCT06828354) | Jiangsu HengRui Medicine Co., Ltd. | 2025-03-13 |
| HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer (NCT06855069) | Hansoh BioMedical R&D Company | 2025-03-13 |
| A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic Arthritis (NCT06869551) | Bristol-Myers Squibb | 2025-03-13 |
| Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight (NCT06858839) | Amgen | 2025-03-12 |
| Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer (NCT06580314) | NRG Oncology | 2025-03-12 |
| A Phase III Clinical Study of QY201 Tablet in Subjects With Moderate to Severe Atopic Dermatitis. (NCT07180511) | E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd. | 2025-03-12 |
| L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML (NCT06788756) | Moleculin Biotech, Inc. | 2025-03-12 |
| A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection (NCT06903338) | Vir Biotechnology, Inc. | 2025-03-12 |
| A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2) (NCT06615479) | Juno Therapeutics, Inc., a Bristol-Myers Squibb Company | 2025-03-12 |
| Newly-diagnosed Pediatric T-cell ALL Protocol (NCT06855810) | Institute of Hematology & Blood Diseases Hospital, China | 2025-03-11 |
| Safety and Efficacy of VDPHL01 in Males With AGA (NCT06972264) | Veradermics, Inc. | 2025-03-11 |
| Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301) (NCT06846515) | Arthrosi Therapeutics | 2025-03-11 |
| A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine (NCT06641466) | Pfizer | 2025-03-11 |
| An Open-label Study to Evaluate the Pharmacokinetics and Safety of Bimekizumab in Pediatric Study Participants With Active Juvenile Idiopathic Arthritis Subtypes Enthesitis-related Arthritis (Including Juvenile-onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis (NCT06668181) | UCB Biopharma SRL | 2025-03-11 |
| A Long-term Extension Clinical Study of TLL-018 in Patients With Rheumatoid Arthritis (NCT06887127) | Hangzhou Highlightll Pharmaceutical Co., Ltd | 2025-03-10 |
| Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage (NCT06322953) | Walton Centre NHS Foundation Trust | 2025-03-10 |
| The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure (NCT07008365) | Instituto de Investigación Sanitaria Aragón | 2025-03-10 |
| Evaluating the Safety and Efficacy of Duloxetine in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis (NCT06860984) | Tanta University | 2025-03-10 |
| Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1) (NCT06822049) | State University of New York at Buffalo | 2025-03-10 |
| A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines (NCT06671496) | Takeda | 2025-03-10 |
| Dexamethasone as ESPB Adjuvant in Lumbar Laminectomy (NCT07429708) | Udayana University | 2025-03-10 |
| Clinical Study of Geranium Wilfordii Combined With Androgen Deprivation in Neoadjuvant Therapy of Prostate Cancer (NCT06861166) | baotai Liang | 2025-03-10 |
| Randomized Controlled Physical Activity App Intervention for Black Women (NCT07114900) | Stony Brook University | 2025-03-09 |
| Corticosteroids for Doxorubicin Liposome-Induced Hand-Foot-Skin Reactions (NCT07362914) | Fudan University | 2025-03-07 |
| 52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism (NCT06689085) | Halozyme Therapeutics | 2025-03-07 |
| A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women (NCT06592586) | Minervax ApS | 2025-03-07 |
| Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases (NCT06391242) | Canadian Cancer Trials Group | 2025-03-07 |
| LINX vs Fundoplication (NCT07093359) | University of Oxford | 2025-03-06 |
| Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog Alfa (NCT06716814) | Swedish Orphan Biovitrum | 2025-03-06 |
| Meniscal INfiltration of Corticosteroid Guided With Ultra Sonography (NCT06527235) | University Hospital, Toulouse | 2025-03-06 |
| A Study to Determine the Safety and Efficacy of NT-501 With MHFM (NCT06397131) | Neurotech Pharmaceuticals | 2025-03-06 |
| Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness (NCT06821295) | University of Oklahoma | 2025-03-05 |
| A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With Obesity (NCT06859268) | Eli Lilly and Company | 2025-03-05 |
| A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL) (NCT06742996) | BeOne Medicines | 2025-03-05 |
| Progesterone-modified Natural Cycle for FET (NCT06644794) | Shandong University of Traditional Chinese Medicine | 2025-03-05 |
| Local Antibiotic Delivery for Community Acquired Pneumonia (NCT06859450) | Copenhagen Respiratory Research | 2025-03-04 |
| Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial (NCT06500481) | NRG Oncology | 2025-03-04 |
| Dentinal Hypersensitivity Reduction Efficacy Study (NCT06960148) | Colgate Palmolive | 2025-03-04 |
| Bevacizumab-based Chemotherapy Adapted to Bevacizumab Pharmacokinetics in 1st-line Treatment (NCT06642844) | University Hospital, Tours | 2025-03-04 |
| Multiple Micronutrient Supplementation for Maternal Anemia Prevention in Tanzania (NCT06079918) | George Washington University | 2025-03-03 |
| Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy (NCT06947330) | Kholoud Usama | 2025-03-03 |
| A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure (NCT06742723) | AstraZeneca | 2025-03-03 |
| 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration (NCT06864988) | 4D Molecular Therapeutics | 2025-03-03 |
| Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder (NCT06830044) | Vanda Pharmaceuticals | 2025-03-03 |
| A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines (NCT06671483) | Takeda | 2025-03-03 |
| Newly-diagnosed Low Risk Pediatric B-cell ALL Protocol (NCT06882057) | Institute of Hematology & Blood Diseases Hospital, China | 2025-03-03 |
| Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients (NCT06619912) | Xijing Hospital | 2025-03-03 |
| Therapeutic Effect of Proliferative Therapy (Prolotherapy) on Pain Using Injectable Hypertonic Dextrose 25% Versus Injectable Dextrose 10% in Retrodiscal Tissues in Patients With Anterior Disc Displacement With Reduction: A Randomized Clinical Trial . (NCT06859034) | Cairo University | 2025-03-03 |
| Effect of Probiotics "Psychobiotics" on Depression and Metabolic Syndrome in Saudi Arabia (NCT06765057) | Roaa Ahmed Alkreadees | 2025-03-02 |
| Impact of Varying Doses of Prucalopride on Improving Gut Function Recovery After Elective Colorectal Surgery (NCT06816407) | Future University in Egypt | 2025-03-02 |
| The Effectiveness and Safety of Cleanser Containing Triethyl Citrate, Pyruvic Acid, Combination Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic Acid and Spot Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Honokiol (NCT06775314) | Dr.dr.Irma Bernadette, SpKK (K) | 2025-03-01 |
| Hydration and Acceptability of the Genital and Skin Mucosa of a Vaginal Moisturizer in Menopausal Women (NCT06564883) | Biolab Sanus Farmaceutica | 2025-03-01 |
| Clinical Study on the Intervention of Xuesaitong Soft Capsules in Post-Intervention Patients with Acute Coronary Syndrome and Clinical Research Protocol (NCT06845254) | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 2025-03-01 |
| Medication Withdrawal in Stable HF With Improved LVEF (NCT07489547) | Hospital de Clinicas de Porto Alegre | 2025-03-01 |
| Observation of the Effect of Preoperative Use of Dexmedetomidine Hydrochloride Nasal Spray on Optimizing Awake Sedation During Breast-Conserving Surgery for Breast Cancer and Postoperative Awake Status (NCT07350928) | Tianjin Medical University Cancer Institute and Hospital | 2025-03-01 |
| CRYoablation for Small Tumors As Local Treatment - SIX Trial (NCT06839001) | Hospital do Coracao | 2025-03-01 |
| The Effect of Oral Gabapentin on Emergence Agitation and Delirium in Adult Patients After Nasal Surgery. (NCT06887998) | Cairo University | 2025-03-01 |
| The Effect of Discontinuation of Renin Angiotensin System Inhibitors on the Perioperative Myocardial Injury in Adult Patients Undergoing Colorectal Cancer Surgery (NCT06862115) | Kasr El Aini Hospital | 2025-03-01 |
| A Clinical Study Comparing Chemotherapy Combined With PD-1 Inhibitor Versus Concurrent Chemoradiotherapy in Cervical Cancer Patients With Positive Lymph Nodes After Surgery: A Multicenter Randomized Controlled Clinical Trial (NCT06866951) | Women's Hospital School Of Medicine Zhejiang University | 2025-03-01 |
| Comparison of Bupivacaine Wound Infiltration Versus Wound Instillation to Minimize Postoperative Pain After Thyroid Surgery (NCT06789575) | Assiut University | 2025-03-01 |