| The Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult Patients (NCT06901297) | Materia Medica Holding | 2025-04-03 |
| Clinical Trial to Evaluate the Efficacy and Safety of Co-administration of JW0108+C2407 in Patients With Dyslipidemia (NCT06955104) | JW Pharmaceutical | 2025-04-03 |
| A Study of the Efficacy and Safety of Cyclosporin Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease (NCT06766357) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2025-04-03 |
| A Study to Evaluate the Efficacy and Safety of Glumetinib Combined With Osimertinib Mesylate Versus Platinum-based Doublet Chemotherapy in Non-Small Cell Lung Cancer Patients After Resistance to EGFR-TKIs (NCT06829459) | Shanghai JMT-Bio Inc. | 2025-04-03 |
| Efficacy and Safety of SLIT in Patients With Rhinitis/RC With/Without Mild-moderate Asthma, Due to Dpt and/or Df (NCT07348302) | Inmunotek S.L. | 2025-04-02 |
| A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203) (NCT06615050) | Incyte Corporation | 2025-04-02 |
| Efficacy of Antibiotic Treatment for Patients With Chronic Low Back Pain and Modic Type I Changes - Randomized Placebo-controlled Trial (NCT06771492) | Bart Koes | 2025-04-02 |
| A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During Surgery (NCT06664775) | Corza Medical GmbH | 2025-04-02 |
| Effect of Remimazolam Sedation on Outcomes of Mechanically Ventilated Patients in the ICU (NCT07596589) | Southeast University, China | 2025-04-01 |
| Evaluation of Efficacy and Safety of Intradiscal Gelified Ethanol in Refractory Cervical Discogenic Pain (NCT05969392) | Gelscom SAS | 2025-04-01 |
| Phase 2/3 Study of TLC590 for Postsurgical Pain Management (NCT05161637) | Taiwan Liposome Company | 2025-04-01 |
| Nebivolol ANOCA Treatment Randomized Trial (NCT06755801) | Spanish Society of Cardiology | 2025-04-01 |
| To Investigate the Efficacy and Safety of UB-421 Monotherapy in HIV-1 Infected Adults (NCT03149211) | United BioPharma | 2025-04-01 |
| Pre-Operative Treatment in REseCTable COlon CanceR (NCT06899477) | Dominik Paul Modest | 2025-04-01 |
| Tailoring Obesity Treatment Trial (NCT06619015) | Esbjerg Hospital - University Hospital of Southern Denmark | 2025-04-01 |
| Phase 3 Trial Comparing IMRT or IMPT Plus CIRT for Patients With NPC (NCT06846450) | Lin Kong, MD | 2025-04-01 |
| A Study to Evaluate the Efficacy and Safety of HLX15-IV Versus DARZALEX® in Combination with Lenalidomide-Dexamethasone (Rd) in Transplant-ineligible Patients with Newly Diagnosed Multiple Myeloma (NCT06895512) | Shanghai Henlius Biotech | 2025-04-01 |
| Comparison of Curcumin and Intralesional Steroids in Oral Submucous Fibrosis (NCT06758739) | Services Institute of Medical Sciences, Pakistan | 2025-04-01 |
| Effect of Colloids Versus Crystalloids on Heart Mechanics: a Double-blind Cross Over Randomized Trial (NCT06900972) | University of Monastir | 2025-04-01 |
| Reducing Dose and Irradiated Volume in Cervical Prophylactic Irradiation for Nasopharyngeal Cancer (NCT06775756) | Fujian Cancer Hospital | 2025-04-01 |
| Sirolimus for Injection (Albumin-bound) Combined With Fulvestrant for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Previously Treated With CDK4/6 Inhibitors (NCT06929325) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2025-04-01 |
| Oral Bisoprolol Vs IV Diltiazem in Atrial Fibrillation or Flutter With Rapid Ventricular Rate. (NCT06276127) | Oman Medical Speciality Board | 2025-04-01 |
| The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin (NCT05961501) | Wroclaw Medical University | 2025-04-01 |
| Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP (NCT06859099) | Sanofi | 2025-04-01 |
| Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution Working (NCT06980493) | Sohag University | 2025-04-01 |
| Trifluridine/Tipiracil Plus Regorafenib vs Trifluridine/Tipiracil Plus Bevacizumab for Refractory Metastatic Colorectal Cancer (NCT06992648) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-04-01 |
| Glumetinib Combined With Osimertinib Treatment for Non-Small Cell Lung Cancer Patients (NCT06908772) | Shanghai JMT-Bio Inc. | 2025-04-01 |
| Phase III Clinical Trial to Evaluate INR101 Injection for PET/CT Imaging in Patients With Prostate Cancer. (NCT06922903) | Yunhe Pharmaceutical (Tianjin) Co., Ltd | 2025-04-01 |
| ZyVac-TCV Bangladesh Study (NCT06757283) | International Centre for Diarrhoeal Disease Research, Bangladesh | 2025-04-01 |
| Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions (NCT07113847) | British University In Egypt | 2025-04-01 |
| Comparative Study Between the Effect of Dexmedetomidine ,Midazolam or Bupivacaine Packing During FESS on Surgical Field Visualization (NCT07013955) | Minia University | 2025-04-01 |
| Non-interference Study of MR and Yellow Fever Vaccines Among Bangladeshi Infants Aged 9-12 Months (NCT06815835) | International Centre for Diarrhoeal Disease Research, Bangladesh | 2025-04-01 |
| Preoperative Block for Anterior Cervical Spine Surgery (NCT06867510) | Tanta University | 2025-04-01 |
| Paclitaxel Lipid Suspension for Patients with Platinum-Resistant /Refractory Ovarian Cancer (NCT06867562) | Jina Pharmaceuticals Inc. | 2025-04-01 |
| Randomized Controlled Trial of Remote Symptoms Monitoring With Resilience PRO Compared to Care As Usual Only (NCT06867705) | Resilience | 2025-04-01 |
| A Phase Ⅲ Comparative Study of QL2108 to Dupixent® (NCT06884891) | Qilu Pharmaceutical Co., Ltd. | 2025-04-01 |
| Blinatumomab for Treatment of Refractory Myasthenia Gravis (NCT06836973) | Da, Yuwei, M.D. | 2025-04-01 |
| Tissue Repair Gel in Venous Leg Ulcers in AU/US (NCT06707103) | TR Therapeutics | 2025-04-01 |
| Antimicrobial Adjuvants to Revert the Imbalance of Skin Microbiota for Improved Outcomes of Complicated Cutaneous Leishmaniasis Treatment in Ethiopia (NCT06695143) | Institute of Tropical Medicine, Belgium | 2025-04-01 |
| A Clinical Trial to Evaluate The Effects of Semaglutide and Empagliflozin Combined to Automated Insulin Delivery on Diabetes Control in Adults Living With Type 1 Diabetes (NCT06894784) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2025-04-01 |
| Immediate Versus Delayed Treatment With Azathioprine or Rituximab in Anti-MOG Antibodies Associated Acute Demyelinating Syndromes in Children: a Randomized Controlled Clinical Trial (NCT05545384) | Assistance Publique - Hôpitaux de Paris | 2025-04-01 |
| A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's (NCT04664634) | Northwestern University | 2025-04-01 |
| Alginate vs Sucralfate for GERD Symptomatic Relief (NCT07310927) | CMH Lahore Medical College and Institute of Dentistry | 2025-04-01 |
| Insulin Producing Stem Cell Transplantation Clinical Trial in Type 1 Diabetes (NCT06951074) | Ain Shams University | 2025-04-01 |
| Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial (NCT06498635) | National Cancer Institute (NCI) | 2025-04-01 |
| Low Dose Edoxaban in Elderly Patients With AF and a History of Stroke (NCT06900725) | National Taiwan University Hospital | 2025-04-01 |
| Methylprednisolone With Endovascular Thrombectomy for Large Ischemic Stroke (NCT06870448) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2025-04-01 |
| AZA+Lus VS AZA Monotherapy in HR-MDS (NCT06927232) | Peking Union Medical College Hospital | 2025-04-01 |
| A Multicenter, Open-label, Prospective Phase III Clinical Trial to Evaluate INR101 Injection for PET/CT Imaging in Participants With Suspected Recurrent Prostate Cancer After Radical Treatment (NCT06922929) | Yunhe Pharmaceutical (Tianjin) Co., Ltd | 2025-04-01 |
| Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients (NCT06935292) | Tanta University | 2025-04-01 |
| A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata (NCT06873945) | Pfizer | 2025-04-01 |
| NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) (NCT06911112) | Neurocrine Biosciences | 2025-03-31 |
| Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains. (NCT06866613) | Teikoku Seiyaku Co., Ltd. | 2025-03-31 |
| Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II (NCT06615102) | Universität Münster | 2025-03-31 |
| To Evaluate the Clinical Study of GS1191-0445 Injection in the Treatment of Hemophilia A (NCT06833983) | Gritgen Therapeutics Co., Ltd. | 2025-03-31 |
| The Efficacy and Safety of Efsubaglutide Alfa Injection in Overweight and Obese Subjects (ENLIGHT) (NCT06921486) | Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. | 2025-03-31 |
| An Open-label Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Immunogenicity of SKP-0141 for the Treatment and Prophylaxis in Severe Hemophilia a Patients (NCT06738901) | SK Plasma Co., Ltd. | 2025-03-31 |
| Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III) (NCT06832917) | Wan He | 2025-03-31 |
| The Effect of Music on the Sedation Quality Among Children in the Emergency Department. (NCT06876194) | Tehran University of Medical Sciences | 2025-03-31 |
| An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant (NCT06832410) | Vertex Pharmaceuticals Incorporated | 2025-03-31 |
| Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC（SYNSTAR01） (NCT06927986) | CSPC Megalith Biopharmaceutical Co.,Ltd. | 2025-03-30 |
| Olanzapine in the Prevention and Treatment of Anorexia-Cachexia Syndrome in Patients Receiving Neoadjuvant/Preoperative Chemotherapy (NCT07633236) | Blokhin's Russian Cancer Research Center | 2025-03-28 |
| LC-Plasma for Preventing URTIs and Reducing Symptoms (NCT06827327) | RDC Clinical Pty Ltd | 2025-03-28 |
| Evaluating the Efficacy of RELiZORB in Managing Exocrine Pancreatic Insufficiency in Tube-fed Pancreatitis Patients (NCT06691893) | Massachusetts General Hospital | 2025-03-28 |
| Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment (NCT06750289) | AstraZeneca | 2025-03-28 |
| Evaluate the Safety and Efficacy of HDM1002 Tablets in Chinese Overweight and Obese Adults (NCT06885021) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2025-03-28 |
| Newly-diagnosed Pediatric Ph-positive B-ALL Protocol (NCT07152041) | Institute of Hematology & Blood Diseases Hospital, China | 2025-03-28 |
| Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment (NCT06589804) | National Cancer Institute (NCI) | 2025-03-27 |
| Gemcitabine Plus Nab-paclitaxel as Switch Maintenance Versus Continuation of Modified FOLFIRINOX as 1st Line Chemotherapy in Patients With Advanced Pancreatic Cancer. (NCT06897644) | Gruppo Oncologico del Nord-Ovest | 2025-03-27 |
| DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer (NCT06989112) | AstraZeneca | 2025-03-27 |
| Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (NCT06443606) | Assistance Publique - Hôpitaux de Paris | 2025-03-27 |
| A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer. (NCT06844357) | Zhejiang Raygene Pharmaceuticals Co., Ltd | 2025-03-27 |
| Study of Yupingfeng Powder Treating Allergic Rhinitis (AR) (NCT06608017) | Chinese University of Hong Kong | 2025-03-27 |
| Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer (NCT06890598) | Eli Lilly and Company | 2025-03-27 |
| Evaluation of D-Fi for the Treatment of Wounds Due to DEB (NCT06892639) | Castle Creek Biosciences, LLC. | 2025-03-27 |
| A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01) (NCT06644781) | Daiichi Sankyo | 2025-03-27 |
| ENERGY 2: Evaluation of the Efficacy and Safety of INZ-701 in Infants With ENPP1 Deficiency (NCT07473973) | Inozyme Pharma | 2025-03-26 |
| Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS (NCT06126315) | Mario Negri Institute for Pharmacological Research | 2025-03-26 |
| P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety (NCT06973577) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2025-03-26 |
| Phase 3 Clinical Trial to Evaluate Paracetamol /Fexofenadine /Phenylephrine in Flu and Cold Treatment (NCT05118672) | Eurofarma Laboratorios S.A. | 2025-03-26 |
| Phase III Clinical Trial of STSP-0601 for Injection in Hemophilia Patients (NCT06922045) | Jiangsu BioJeTay Biotechnology Co., Ltd. | 2025-03-26 |
| Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer (NCT06028737) | Ukrainian Society of Clinical Oncology | 2025-03-25 |
| Clinical Trial of MG-K10 in Stage III of Moderate to Severe Asthma (NCT06837922) | Shanghai Mabgeek Biotech.Co.Ltd | 2025-03-25 |
| A Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (NCT06907290) | Mirum Pharmaceuticals, Inc. | 2025-03-25 |
| A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Urothelial Carcinoma(PANKU-Bladder01) (NCT06857175) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-03-25 |
| Anticholinergics for Cervical Edema in Labor (NCT06702670) | The University of Texas Health Science Center, Houston | 2025-03-25 |
| Nicotine Patch Plus Nicotine Mouth Spray Versus Nicotine Reduction for Vaping Cessation (NCT06832098) | University of Auckland, New Zealand | 2025-03-25 |
| Safety and Efficacy Study of YZJ-1139 Tablets in Insomnia Disorder (NCT06975514) | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | 2025-03-25 |
| A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007) (NCT06878261) | AstraZeneca | 2025-03-25 |
| Memantine as an Additive Therapy in Patients With Traumatic Brain Injury (NCT06914310) | Mansoura University | 2025-03-25 |
| Effect of Biofeedback Tongue Strengthening Program on Tongue Pressure and Swallowing Performance (NCT07080996) | Mahidol University | 2025-03-25 |
| Neoadjuvant Chemotherapy in Combination With Toripalimab for HR+/HER2- Breast Cancer : a Randomized, Open-label, Parallel-controlled, Multi-center Phase III Study (NEOTORCH-BREAST04) (NCT06977893) | First Affiliated Hospital of Zhejiang University | 2025-03-24 |
| Evaluation of the Effect of a Toothpaste Containing 0.3% Chlorhexidine in Subjects With Established Dental Plaque and Gingivitis (NCT06732466) | Colgate Palmolive | 2025-03-24 |
| Canadian Critical Care Comparative Effectiveness Platform (NCT06605144) | Université de Sherbrooke | 2025-03-23 |
| Inter-lot Consistency Clinical Trial of Adsorbed Cell-free DTP (Three-component) Combined Vaccine (NCT06857370) | CanSino Biologics Inc. | 2025-03-23 |
| The Efficacy and Safety of Dapagliflozin in the Treatment of Hereditary Kidney Disease With Proteinuria in Children (NCT06890143) | Children's Hospital of Fudan University | 2025-03-22 |
| Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART) (NCT06922240) | Suqiao Yang | 2025-03-21 |
| Alternative RUTFs for Treatment of Child Wasting (NCT06912620) | International Food Policy Research Institute | 2025-03-21 |
| Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis (NCT06911424) | Baxis Pharmaceuticals, Inc. | 2025-03-21 |
| Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004) (NCT06726265) | Immutep S.A.S. | 2025-03-21 |