| A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy (NCT07021976) | Shandong Suncadia Medicine Co., Ltd. | 2025-08-11 |
| A Long-Term Study of JNT-517 in Participants With Phenylketonuria (NCT06628128) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2025-08-11 |
| Nanocrystalline Megestrol for Managing Chemotherapy-Induced Nausea and Vomiting (NCT07124195) | The First Affiliated Hospital of Xinxiang Medical College | 2025-08-10 |
| Clinical Trial to Evaluate the Efficacy and Safety of EEC for the Diagnosis of Mycobacterium Tuberculosis Infection in People Aged 3 Years and Above (NCT07152639) | Chengdu CoenBiotech Co., Ltd | 2025-08-09 |
| Intra-arterial Methylprednisolone After Successful Endovascular Thrombectomy Anterior Circulation Large Vessel Occlusion (NCT07141303) | Tang-Du Hospital | 2025-08-08 |
| A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression) (NCT07172516) | Xenon Pharmaceuticals Inc. | 2025-08-08 |
| Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis (NCT07109869) | pH-D Feminine Health LLC | 2025-08-08 |
| A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism (NCT07007793) | AstraZeneca | 2025-08-07 |
| The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled Trial (NCT07114640) | Far Eastern Memorial Hospital | 2025-08-07 |
| Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung Cancer (NCT06732401) | National Cancer Institute (NCI) | 2025-08-07 |
| A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes (NCT07088068) | Sanofi | 2025-08-06 |
| Nudging Effective and Equitable Delivery of Specialty Palliative Care (NCT06596577) | University of Pennsylvania | 2025-08-06 |
| A Pilot Trial Comparing Full Dose Rivaroxaban to Prophylactic Dose Rivaroxaban in Patients With Superficial Vein Thrombosis in the Leg (NCT06965998) | Ottawa Hospital Research Institute | 2025-08-06 |
| A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer (NCT06774131) | UroGen Pharma Ltd. | 2025-08-06 |
| A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients (NCT07103668) | Suzhou Immunofoco Biotechnology Co., Ltd | 2025-08-06 |
| A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma (NCT06624644) | Linnaeus Therapeutics, Inc. | 2025-08-06 |
| A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation (NCT06952803) | AstraZeneca | 2025-08-06 |
| Y-6 Sublingual Tablets for Patients With Acute Ischemic Stroke (NCT07040085) | Beijing Tiantan Hospital | 2025-08-05 |
| Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata (NCT07133308) | Sun Pharmaceutical Industries, Inc. | 2025-08-05 |
| Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy (NCT07075016) | Stichting Hemato-Oncologie voor Volwassenen Nederland | 2025-08-05 |
| A Study of mRNA-1345 Following a Primary Dose of a Licensed Protein Subunit Respiratory Syncytial Virus (RSV) Vaccine in Adult Participants ≥60 Years of Age (NCT07117487) | ModernaTX, Inc. | 2025-08-05 |
| Therapeutic Effect of Microfragmented Adipose Tissue (Lipogems) Injection on Maximum Interincisal Opening Versus Injectable Platelet-rich Plasma (PRP) for the Treatment of Anterior Disc Displacement With Reduction : A Randomized Clinical Trial (NCT07107399) | Cairo University | 2025-08-05 |
| A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment. (NCT07062965) | Pfizer | 2025-08-05 |
| Evaluation of 611 in Chinese Adolescents With Moderate to Severe Atopic Dermatitis (NCT07042126) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2025-08-05 |
| Improving Mobility After Revascularization in Peripheral Artery Disease (NCT06686121) | Northwestern University | 2025-08-04 |
| Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR (NCT06790784) | Jaeb Center for Health Research | 2025-08-04 |
| A Multicenter Study of IBI343 Monotherapy Versus Placebo in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, Pancreatic Cancer(G-HOPE-002) (NCT07066098) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-08-04 |
| ASKC202 Combined With Limertinib Versus Platinum-based Chemotherapy in Treatment of Locally Advanced or Metastatic NSCLC With MET Amplification/Overexpression After Failure of EGFR-TKI Therapy (NCT07109531) | Jiangsu Aosaikang Pharmaceutical Co., Ltd. | 2025-08-04 |
| Heparin for RAO Post-Transradial Angiography in AIS (NCT07162064) | Xiang Luo | 2025-08-04 |
| A Study Comparing BL-B01D1 With the Investigator's Choice of Chemotherapy in Patients With Platinum-resistant Recurrent Epithelial Ovarian Cancer(PANKU-GYN01) (NCT06994195) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-08-04 |
| A Study of Dotinurad Versus Allopurinol in Tophaceous Gout (NCT07089888) | Crystalys Therapeutics | 2025-08-04 |
| A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer (NCT07005102) | AbbVie | 2025-08-03 |
| Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK) (NCT07095842) | Sohag University | 2025-08-03 |
| Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff Pressure (NCT07315490) | PAEC General Hospital, Islamabad | 2025-08-02 |
| Tranexamic Acid : Nebulization vs IV Route for Hemoptysis (NCT07212452) | University of Health Sciences Lahore | 2025-08-01 |
| GM1 Prophylaxis for Nab-paclitaxel-associated Chemotherapy-induced Peripheral Neuropathy (CIPN) in Patients With Breast Cancer (NCT06994507) | Qilu Pharmaceutical Co., Ltd. | 2025-08-01 |
| Investigating the Adjunctive Use of Mirabegron in the Early Post-Rezum Procedure Period (NCT07017439) | University of Manitoba | 2025-08-01 |
| Organoid-guided vs Topotecan Therapy in Relapsed Extensive-Stage Small Cell Lung Cancer (NCT07106528) | Peking Union Medical College Hospital | 2025-08-01 |
| Clinical Study on the Efficacy and Safety of Telitacicept in the Treatment of Pediatric IgA Nephropathy or IgA Vasculitis Nephritis (NCT07052981) | Guixia Ding | 2025-08-01 |
| Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder (NCT06559995) | University of Pennsylvania | 2025-08-01 |
| Clinical Trial to Evaluate the Protective Efficacy and Safety of a Nasal Spray Live Attenuated Influenza Vaccine (LAIV) in Adults Aged 18-59 Years Post-Vaccination (NCT07133802) | Changchun BCHT Biotechnology Co. | 2025-08-01 |
| Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner (NCT07103551) | Al-Azhar University | 2025-08-01 |
| Effect of Baclofen in Management of Patients With Gastroesophageal Reflux Disease Symptoms (NCT07063576) | Adnan Imtiaj Rahul | 2025-08-01 |
| Shrinking the Anterior Border of CTV2 for Nasopharyngeal Carcinoma to Reduce the Radiation of Nasal Cavity (NCT07072000) | Hai-Qiang Mai,MD,PhD | 2025-08-01 |
| Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT) (NCT07462260) | Sindh Institute of Cardiovascular Diseases | 2025-08-01 |
| Chamomile Gummies and Pediatric Dental Anxiety (NCT07138391) | Ain Shams University | 2025-08-01 |
| Virtual Reality for Pain and Anxiety Relief During Peripheral Angioplasty (NCT07057752) | Kastamonu University | 2025-08-01 |
| A Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Suraxavir Marboxil for Suspension (NCT07113392) | Jiangxi Kvvit Pharmaceutical Co., Ltd. | 2025-08-01 |
| A Study of Dotinurad Versus Allopurinol in Participants With Gout (NCT07089875) | Crystalys Therapeutics | 2025-08-01 |
| Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome (NCT07135167) | Woolfson Eye Institute | 2025-08-01 |
| 1HP Versus 3HR in the Treatment of Tuberculosis Infection in Vietnam (NCT06191692) | Freundeskreis Für Internationale Tuberkulosehilfe e.V | 2025-08-01 |
| Treatment of Acute Ischemic Stroke With Edaravone Dexborneol Sublingual Tablets in Small Vessel Disease (NCT06674460) | Peking Union Medical College Hospital | 2025-08-01 |
| Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases (NCT07124910) | Woolfson Eye Institute | 2025-08-01 |
| Mandibular Advancement Devices for Reflux in Obstructive Sleep Apnea (NCT07049315) | Tuiuti University of Paraná | 2025-08-01 |
| A Phase III Clinical Study of H077 Sustained-Release Tablets Compared With Silodosin Capsules in the Treatment of Benign Prostatic Hyperplasia (NCT07146386) | Shanghai Huilun Pharmaceutical Co., Ltd. | 2025-08-01 |
| A Study to Evaluate Safety and Efficacy of PBK_M2502 (NCT07114406) | Pharmbio Korea Co., Ltd. | 2025-08-01 |
| Trial to Assess the Efficacy and Safety During Convective Radiofrequency Water Vapor Thermal Therapy (REZUM) for Benign Prostate Hyperplasia (NCT07017452) | University of Manitoba | 2025-08-01 |
| Phase III Clinical Study on the Efficacy and Safety of Semaglutide and Ozempic® in Patients With Type 2 Diabetes (NCT07046273) | Shandong New Time Pharmaceutical Co., LTD | 2025-08-01 |
| Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01) (NCT07044336) | AstraZeneca | 2025-08-01 |
| Unilateral Right-Sided Erector Spinae Plane Block for Analgesia in Laparoscopic Cholecystectomy: Does the Volume Matter? A Randomized Controlled Trial (NCT07027540) | Assiut University | 2025-08-01 |
| A Study of Collagen Scaffold for the Repair of Elbow Cartilage Injury (NCT07149896) | Beijing Jishuitan Hospital | 2025-08-01 |
| Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 Study (NCT07132463) | Fudan University | 2025-08-01 |
| SLGT2i for Neuroprotection in Patients With Acute Ischemic Stroke (NCT07105917) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-08-01 |
| A Phase III Study to Evaluate the Efficacy and Safety of ZM-H1505R in Patients With CHB (NCT07095855) | Shanghai Zhimeng Biopharma, Inc. | 2025-08-01 |
| A Prospective Multicenter RCT Study of Deep Jugular Lymphovenous Anastomosis in the Treatment of Alzheimer's Disease (NCT07060391) | Shanghai Jiao Tong University School of Medicine | 2025-07-31 |
| A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata (NCT07029711) | Pfizer | 2025-07-31 |
| A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011) (NCT07044297) | Merck Sharp & Dohme LLC | 2025-07-31 |
| Clinical Trial of Freeze-dried Human Rabies Vaccine (Human Diploid Cells) (NCT07028801) | Ningbo Rongan Biological Pharmaceutical Co., Ltd. | 2025-07-31 |
| Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial (NCT06949228) | ProMedica Health System | 2025-07-30 |
| A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide (NCT07128550) | Vir Biotechnology, Inc. | 2025-07-30 |
| Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ischemic Stroke (NCT07047014) | Beijing Tiantan Hospital | 2025-07-30 |
| Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial (NCT06850090) | Shandong Cancer Hospital and Institute | 2025-07-30 |
| A Clinical Trial of Anaprazole for Treating Reflux Esophagitis. (NCT07010107) | Xuanzhu Biopharmaceutical Co., Ltd. | 2025-07-30 |
| Efficacy and Safety of Efsubaglutide Alfa Injection 3 Mg Q2W in T2D Patients (NCT06900075) | Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. | 2025-07-30 |
| Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee (NCT04433572) | Mercator MedSystems, Inc. | 2025-07-30 |
| A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK (NCT06990399) | Kodiak Sciences Inc | 2025-07-30 |
| A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease (NCT06328608) | Chiesi Farmaceutici S.p.A. | 2025-07-29 |
| Non-invasive Ventilation and Dexmedetomidine in Critically Ill Adults (NCT06259565) | St. Joseph's Healthcare Hamilton | 2025-07-29 |
| Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps (NCT06850805) | Optinose US Inc. | 2025-07-28 |
| NEO-BLAST: Neoadjuvant Therapy for Bladder Cancer Followed by Active Surveillance vs Treatment (NCT06537154) | Peter Black | 2025-07-28 |
| Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B (NCT07080905) | CSL Behring | 2025-07-28 |
| A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients for Postoperative Pain Treatment in Orthopedic Surgery (NCT07186426) | Haisco Pharmaceutical Group Co., Ltd. | 2025-07-28 |
| Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy. (NCT06858319) | Novartis Pharmaceuticals | 2025-07-28 |
| A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis (NCT07071519) | AbbVie | 2025-07-28 |
| A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4) (NCT06911502) | Celgene | 2025-07-28 |
| A Prospective, Open-label, Pivotal Study to Assess Spectacle Hearing Aid Safety and Efficacy (NCT07282028) | Nuance Hearing | 2025-07-27 |
| A Phase III Study Evaluating the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity (NCT06974851) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2025-07-25 |
| Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387 (NCT07010159) | Kiniksa Pharmaceuticals International, plc | 2025-07-25 |
| Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity (NCT07037433) | Amgen | 2025-07-25 |
| A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis (NCT06989567) | Asklepion Pharmaceuticals, LLC | 2025-07-25 |
| Ultra-Short Regimen for Elderly DS-TB (NCT07076225) | Shenzhen Third People's Hospital | 2025-07-25 |
| TQB2930 Injection for the Treatment of HER2-positive Advanced Breast Cancer (NCT07047365) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2025-07-25 |
| Efficacy and Safety of HRS9531 in Participants With Type 2 Diabetes Treated With Basal Insulin (NCT07060456) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2025-07-25 |
| Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA) (NCT07146022) | Veradermics, Inc. | 2025-07-25 |
| To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis (NCT06901505) | Akebia Therapeutics | 2025-07-24 |
| Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2) (NCT06757634) | Celcuity Inc | 2025-07-24 |
| A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema (NCT06807268) | Pfizer | 2025-07-24 |
| To Evaluate the Efficacy, Safety and Population Pharmacokinetics of GST-HG141 in Patients With Chronic Hepatitis B (CHB) Who Have an Inadequate Response to Antiviral Drug Treatment (NCT07090759) | Fujian Akeylink Biotechnology Co., Ltd. | 2025-07-24 |
| The Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in Russia (NCT07232134) | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 2025-07-24 |
| Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke (NCT05691244) | Pharmazz, Inc. | 2025-07-24 |