| Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Japanese Adults 60 Years of Age and Older (NCT04498832) | Sanofi Pasteur, a Sanofi Company | 2020-10-21 |
| INB03 for the Treatment of Pulmonary Complications From COVID-19 (NCT04370236) | Inmune Bio, Inc. | 2020-10-21 |
| Efficacy and Safety of AG10 in Subjects with Transthyretin Amyloid Polyneurophathy (NCT04418024) | Eidos Therapeutics, a BridgeBio company | 2020-10-21 |
| Aggrenox To Treat Acute Covid-19 (NCT04410328) | Rutgers, The State University of New Jersey | 2020-10-21 |
| Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer (NCT04464226) | Bayer | 2020-10-20 |
| Economic Evaluation of New MDR TB Regimens (NCT04207112) | Medecins Sans Frontieres, Netherlands | 2020-10-20 |
| Clinical Study to Evaluate the Efficacy and Safety of TQB2440 Injection/Perjeta® Combined With Trastuzumab and Docetaxel in the Treatment of Patients With Early or Locally Advanced Breast Cancer. (NCT05985187) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2020-10-20 |
| Effect of AD128 to Treat Obstructive Sleep Apnea (NCT04394143) | Raphael Heinzer | 2020-10-20 |
| Prevention of Dysrhythmias on the Cardiac Intensive Care Unit - Does Maintenance of High-normal Serum Potassium Levels Matter (NCT04053816) | Barts & The London NHS Trust | 2020-10-20 |
| Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries (NCT04518462) | Pacira Pharmaceuticals, Inc | 2020-10-20 |
| Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC (NCT04550260) | AstraZeneca | 2020-10-19 |
| Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis (NCT04610476) | University of Erlangen-Nürnberg Medical School | 2020-10-19 |
| Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC (NCT04446117) | Exelixis | 2020-10-19 |
| Study Comparing Continuous Subcutaneous Infusion Of ABBV-951 With Oral Carbidopa/Levodopa Tablets For Treatment Of Motor Fluctuations In Adult Participants With Advanced Parkinson's Disease (NCT04380142) | AbbVie | 2020-10-19 |
| A Single Arm Study Evaluating the Efficacy, Safety and Tolerability of Ofatumumab in Patients With Relapsing Multiple Sclerosis (NCT04486716) | Novartis Pharmaceuticals | 2020-10-19 |
| A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin (NCT04537923) | Eli Lilly and Company | 2020-10-19 |
| Pregnancy Outcome and Vitamin D Level Among Vitamin D Supplementation During Pregnancy (NCT04591847) | Department of Medical Services Ministry of Public Health of Thailand | 2020-10-19 |
| An Exploratory Study of PQ Grass 27600 SU (NCT04687059) | Allergy Therapeutics | 2020-10-19 |
| Efficacy and Safety of Molnupiravir (MK-4482) in Hospitalized Adult Participants With COVID-19 (MK-4482-001) (NCT04575584) | Merck Sharp & Dohme LLC | 2020-10-19 |
| Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized Adult Participants With COVID-19 (MK-4482-002) (NCT04575597) | Merck Sharp & Dohme LLC | 2020-10-19 |
| An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-1) (NCT04599933) | Orasis Pharmaceuticals Ltd. | 2020-10-18 |
| Efficacy and Safety of Cladribine Combined With BEAC Pretreatment Regimen in the Treatment of Peripheral T-cell Lymphoma: a Multicenter Clinical Study (NCT04880746) | Ruijin Hospital | 2020-10-17 |
| PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD (NCT04556656) | Prilenia | 2020-10-16 |
| Management of Placenta Accreta Spectrum (NCT04609527) | Assiut University | 2020-10-16 |
| Phase 3 Study to Evaluate the Safety and Efficacy of YPEG-rhG-CSF in Malignancies Receiving Chemotherapy (NCT04466137) | Xiamen Amoytop Biotech Co., Ltd. | 2020-10-16 |
| Medically Ill Hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis With Rivaroxaban ThErapy: The MICHELLE Trial (NCT04662684) | Science Valley Research Institute | 2020-10-16 |
| Efficacy and Safety of Lacidofil® STRONG as an Adjuvant for Helicobacter Pylori Treatment in Non-ulcer Dyspepsia (NCT04473079) | Lallemand Health Solutions | 2020-10-16 |
| Pre-emptive Topical Lidocaine 5% Plaster for Prevention of Post-craniotomy Pain (NCT04169854) | Beijing Tiantan Hospital | 2020-10-15 |
| JUVÉDERM VOLUX® for Chin Retrusion in China (NCT04559984) | Allergan | 2020-10-15 |
| Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection (NCT04553068) | Evofem Inc. | 2020-10-15 |
| An Open Label Study to Determine the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A. (NCT04456387) | Zhengzhou Gensciences Inc | 2020-10-15 |
| Impact of Tissue Plasminogen Activator (tPA) Treatment for an Atypical Acute Respiratory Distress Syndrome (COVID-19) (NCT04453371) | Negovsky Reanimatology Research Institute | 2020-10-15 |
| Efficacy and Safety of Favipiravir in Covid-19 Patients in Indonesia (NCT04613271) | Ina-Respond | 2020-10-15 |
| Percutaneous Coronary Intervention Followed by Antiplatelet Monotherapy in the Setting of Acute Coronary Syndromes (NCT04360720) | Hospital Israelita Albert Einstein | 2020-10-15 |
| Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis (NCT04440189) | GID BIO, Inc. | 2020-10-15 |
| Myasthenia Gravis Inebilizumab Trial (NCT04524273) | Amgen | 2020-10-15 |
| Efficacy of Fecal Microbial Transplantation Treatment in Adults With Atopic Dermatitis (NCT04283968) | Tel-Aviv Sourasky Medical Center | 2020-10-15 |
| Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients (NCT04534959) | University of Colorado, Denver | 2020-10-15 |
| Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC (NCT04723004) | Shanghai Junshi Bioscience Co., Ltd. | 2020-10-15 |
| Immune Modulators for Treating COVID-19 (NCT04593940) | Daniel Benjamin | 2020-10-15 |
| Efficacy and Safety of LY01005 in Patients With Breast Cancer Compared to ZOLADEX® (NCT05110170) | Luye Pharma Group Ltd. | 2020-10-15 |
| Effects of Mass Drug Administration of Azithromycin on Mortality and Other Outcomes Among 1-11 Month Old Infants in Mali (NCT04424511) | Tampere University | 2020-10-15 |
| Amcenestrant (SAR439859) Plus Palbociclib as First Line Therapy for Patients With ER (+) HER2(-) Advanced Breast Cancer (NCT04478266) | Sanofi | 2020-10-14 |
| Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women (NCT07184827) | TCM Biotech International Corp. | 2020-10-14 |
| A Study to Evaluate the Efficacy and Safety of SHR0302 in Patients With Ankylosing Spondylitis (NCT04481139) | Jiangsu HengRui Medicine Co., Ltd. | 2020-10-14 |
| Fulvestrant or Capecitabine Combined With Pyrotinib in HR+/HER2+ Metastatic Breast Cancer (NCT04646759) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2020-10-14 |
| 5% KOH Solution vs. Placebo and Diclofenac Gel for the Treatment of Actinic Keratosis (NCT04552327) | Infectopharm Arzneimittel GmbH | 2020-10-14 |
| PBF-1681 (Ferric Citrate) for the Treatment of IDA in Patients With NDD-CKD (NCT04543812) | Panion & BF Biotech Inc. | 2020-10-14 |
| Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery (NCT04433390) | CMC Ambroise Paré | 2020-10-14 |
| The Effect of the Interaction of Glucagon and Insulin on Endogenous Glucose Production in Humans (NCT04461015) | Adrian Vella | 2020-10-14 |
| Comparison of Immunogenicity and Safety of DTP-HB-Hib (Bio Farma) With Pentabio® Vaccine Primed With Recombinant Hepatitis B (NCT04071379) | PT Bio Farma | 2020-10-13 |
| Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer (NCT04340141) | Alliance for Clinical Trials in Oncology | 2020-10-13 |
| A Study Comparing the Efficacy and Safety Between H-CHOP and R-CHOP in Untreated CD20-Positive Diffuse Large B-cell Lymphoma Patients (NCT05040906) | Shandong New Time Pharmaceutical Co., LTD | 2020-10-13 |
| A Study of Cytisinicline for Smoking Cessation in Adult Smokers (NCT04576949) | Achieve Life Sciences | 2020-10-13 |
| A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions (NCT04538664) | Janssen Research & Development, LLC | 2020-10-13 |
| Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care (the CoV-Early Study) (NCT04589949) | Erasmus Medical Center | 2020-10-12 |
| Fecal Microbiota Transplantation for Carbapenem-resistant Enterobacteriaceae (NCT04146337) | Rambam Health Care Campus | 2020-10-12 |
| Philippine Trial to Determine Efficacy and Safety of Favipiravir for COVID-19 (NCT05014373) | University of the Philippines | 2020-10-12 |
| REMdesivir-HU Clinical Study and Severe Covid-19 Patients (NCT04610541) | University of Pecs | 2020-10-12 |
| Phase II/III of Live Attenuated Mumps (F-genotype) Vaccine (Human Diploid Cell, KMB-17) in Healthy Children Aged 5-11 (NCT04591405) | Institute of Medical Biology, Chinese Academy of Medical Sciences | 2020-10-12 |
| Antibioprophylaxis for Excision-graft Surgery in Burn Patient (A2B-TRIAL) (NCT04292054) | Assistance Publique - Hôpitaux de Paris | 2020-10-11 |
| Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adults in Thaïland (NCT04594551) | Sanofi Pasteur, a Sanofi Company | 2020-10-11 |
| Treatment of Patients With Atherosclerotic Disease With Methotrexate-associated to LDL Like Nanoparticles (NCT04616872) | University of Sao Paulo General Hospital | 2020-10-10 |
| Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients (NCT04329624) | Medical University of Vienna | 2020-10-10 |
| Vortioxetine in the Treatment of Depression Associated With Head and Neck Cancers Undergoing Radiotherapy (NCT04818099) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2020-10-10 |
| Dopamine Versus Norepinephrine Under General Anesthesia (NCT04536194) | Children's Hospital of Fudan University | 2020-10-10 |
| Safety and Efficacy Study of Sofpironium Bromide in Subjects With Axillary Hyperhidrosis (BBI-4000-CL-301) (NCT03836287) | Botanix Pharmaceuticals | 2020-10-09 |
| Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan and Other ARBs on Outcomes of Coronavirus Infection? (NCT04606563) | University of British Columbia | 2020-10-09 |
| A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer) (NCT04546009) | Hoffmann-La Roche | 2020-10-09 |
| Adductor Canal Block (NCT04513145) | OrthoCarolina Research Institute, Inc. | 2020-10-09 |
| Research Study to Compare a New Medicine "Fast-acting Insulin Aspart" to Another Medicine "Insulin Aspart" in Chinese People With Diabetes (NCT04588259) | Novo Nordisk A/S | 2020-10-09 |
| Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma (NCT04307277) | Institut Claudius Regaud | 2020-10-09 |
| A Study To Evaluate The Efficacy And Safety Of a Novel Niclosamide Suspension Formulation For COVID-19 (NCT04558021) | Imuneks Farma ilac San. Tic. A.S. | 2020-10-08 |
| A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312) (NCT04529772) | Acerta Pharma BV | 2020-10-08 |
| MRI-visible Enlarged Perivascular Spaces and the Alteration of Lymphatic Drainage System in CAA (NCT04604587) | National Taiwan University Hospital | 2020-10-08 |
| Inpatient Treatment of COVID-19 With Anti-Coronavirus Immunoglobulin (ITAC) (NCT04546581) | University of Minnesota | 2020-10-08 |
| Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging (NCT04423211) | ECOG-ACRIN Cancer Research Group | 2020-10-08 |
| A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors (NCT04434092) | Hoffmann-La Roche | 2020-10-08 |
| Prophylaxis of Diarrhea in Adult Cancer Patients Receiving Targeted Cancer Therapy (NCT04538625) | Napo Pharmaceuticals, Inc. | 2020-10-07 |
| Al18F-NOTA-octreotide PET Imaging in Neuroendocrine Tumors (NCT04552847) | Universitaire Ziekenhuizen KU Leuven | 2020-10-07 |
| Study of Niclosamide in Moderate and Severe Hospitalized Coronavirus-19 (COVID-19) Patients (NCT04603924) | NeuroBo Pharmaceuticals Inc. | 2020-10-07 |
| Clinical Trial of Favipiravir Treatment of Patients With COVID-19 (NCT04600999) | University of Pecs | 2020-10-07 |
| Comparing the Efficacy and Safety of Intra-peritoneal Infusion of Catumaxomab and Treatment of Investigator Choice in Patients With Advanced Gastric Carcinoma With Peritoneal Metastasis (NCT04222114) | LintonPharm Co.,Ltd. | 2020-10-06 |
| Efficacy and Safety Evaluation for the Treatment of Allergy Against Mites (NCT04435990) | Inmunotek S.L. | 2020-10-06 |
| Tolerability, Safety and Immunogenicity Trial of the Flu-M Quadro, Tetravalent Inactivated Split Influenza Vaccine (NCT05869201) | St. Petersburg Research Institute of Vaccines and Sera | 2020-10-06 |
| A Study of a 2-dose Ebola Vaccine Regimen of Ad26.ZEBOV Followed by MVA-BN-Filo in Healthy Pregnant Women (NCT04556526) | Janssen Vaccines & Prevention B.V. | 2020-10-05 |
| Double-blind, Randomized, Placebo-controlled, Prospective Phase III Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients With Chronic Lymphocytic Leukemia ("PRO-SID" Study) (NCT04502030) | Octapharma | 2020-10-05 |
| Phase III Efficacy and Tolerability Trial of the Fixed Dose Combination of Etodolac 400 mg and Cyclobenzaprine 10 mg Versus Isolated Active Substances in Pain Control After Impacted Third Molar Extraction (NCT03127592) | Apsen Farmaceutica S.A. | 2020-10-05 |
| A Test and Treat Strategy in New HIV Diagnosis. (NCT04416906) | Judit Pich Martínez | 2020-10-05 |
| Heparin vs Placebo for Cardiac Catheterization (NCT04374799) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2020-10-05 |
| A Study of Oral Venetoclax Tablet in Combination With Subcutaneous Low-Dose Cytarabine (LDAC) Injection to Assess Adverse Events in Adult Japanese Participants With Acute Myeloid Leukemia (AML) (NCT04509622) | AbbVie | 2020-10-05 |
| A Phase 2/3 Study to Evaluate the Efficacy and Safety of CT-P59 in Patients With Mild to Moderate SARS-CoV-2 Infection (NCT04602000) | Celltrion | 2020-10-05 |
| Thrombolysis of Urokinase for Minor Stroke (NCT04420351) | The First Affiliated Hospital of Zhengzhou University | 2020-10-04 |
| A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive (NCT04473521) | GlaxoSmithKline | 2020-10-04 |
| A Study to Assess Efficacy and Safety of Bezafibrate in Patients With Primary Biliary Cholangitis (NCT04751188) | Instituto Mexicano del Seguro Social | 2020-10-02 |
| Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer (NCT04590963) | AstraZeneca | 2020-10-02 |
| Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis (NCT03654053) | VA Office of Research and Development | 2020-10-02 |
| The Effect of Pretreatment With Roc on Succinylcholine Myalgias (NCT04581395) | Indiana University | 2020-10-02 |
| Bacteriophage Therapy in Tonsillitis (NCT04682964) | Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan | 2020-10-02 |
| Efficacy and Safety of AngongNiuhuang Pill in Patients With Acute Ischemic Stroke (ANGONG TRIAL) (NCT04475328) | Peking Union Medical College Hospital | 2020-10-01 |