| Impact on General Functionality of an Immediate Prosthetic Functionalization Protocol in People Over 70 Years of Age With Deficient Removable Prostheses (NCT05595304) | Gerardo F Fasce Pineda, MD | 2020-11-03 |
| The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort (NCT04500158) | Virginia Commonwealth University | 2020-11-03 |
| A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES) (NCT04512235) | Alexion Pharmaceuticals, Inc. | 2020-11-03 |
| The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient (NCT04689971) | Duta Wacana Christian University | 2020-11-03 |
| Therapeutic Effectiveness of Different Machines in Intense Pulsed Light Treatment of Meibomian Gland Dysfunction (NCT06034626) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2020-11-03 |
| Short-course Versus Long-course Pre-operative Chemotherapy With mFOLFIRINOX or PAXG (CASSANDRA TRIAL) (NCT04793932) | Associazione Italiana per lo Studio del Pancreas | 2020-11-03 |
| Monosialoganglioside in Acute Ischemic Stroke: a Randomized, Blinded and Multicenter Confirmatory Study (NCT06742216) | Qilu Pharmaceutical Co., Ltd. | 2020-11-03 |
| The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient (NCT04689984) | Duta Wacana Christian University | 2020-11-03 |
| The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient (NCT04689958) | Duta Wacana Christian University | 2020-11-03 |
| (Revival) Study to Investigate the Efficacy and Safety of Alkaline Phosphatase in Patients With Sepsis-Associated AKI (NCT04411472) | AM-Pharma | 2020-11-02 |
| A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes (NCT04596631) | Novo Nordisk A/S | 2020-11-02 |
| Ocrelizumab VErsus Rituximab Off-Label at the Onset of Relapsing MS Disease (NCT04578639) | Haukeland University Hospital | 2020-11-02 |
| Neo-adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma Beyond Milan/UCSF Criteria Who Underwent Liver Transplantation (NCT04595864) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2020-11-01 |
| The DENOCHARCOT Trial (NCT04547348) | Ole Lander Svendsen | 2020-11-01 |
| A Phase III Study of Ciprofloxacin Plus Fluocinolone in Acute Otitis Externa (AOE) (NCT04636957) | Lee's Pharmaceutical Limited | 2020-11-01 |
| Effect of Liraglutide on the Metabolic Profile in Patients With Type 2 Diabetes and Cardiovascular Disease (NCT04057261) | RWTH Aachen University | 2020-11-01 |
| Midodrine and Albumin in Patients With Refractory Ascites (NCT04621617) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2020-11-01 |
| Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma (NCT04829097) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2020-11-01 |
| Clinical Trial of the Immunogenicity, Safety, and Efficacy of the Gam-COVID-Vac Vaccine Against COVID-19 in Venezuela (NCT04642339) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2020-11-01 |
| The Effect of Higher Protein Dosing in Critically Ill Patients Ultrasound a Sub-study (NCT04242966) | Clinical Evaluation Research Unit at Kingston General Hospital | 2020-11-01 |
| Accuracy of VABB Elite 10G Versus BARD 14G CNB (NCT04612439) | Fudan University | 2020-11-01 |
| Esophageal Dysfunction Associated With Opioids: Clinical Response and Manometric Findings After Opioid Discontinuation (NCT06522633) | Hospital Clinic of Barcelona | 2020-11-01 |
| A Phase 3 Study of TAS-205 in Patients With Duchenne Muscular Dystrophy(REACH-DMD) (NCT04587908) | Taiho Pharmaceutical Co., Ltd. | 2020-11-01 |
| A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19 (NCT04605926) | Biocon Limited | 2020-11-01 |
| Nicardipine to Avoid Spasm in Trans Radial Percutaneous Coronary Intervention (NCT04538534) | Pr. Semir Nouira | 2020-11-01 |
| Biofreeze and the Effect on Knee Osteoarthritis (NCT04351594) | Memorial University of Newfoundland | 2020-11-01 |
| Effects of Sevoflurane on Extravascular Lung Water and Pulmonary Vascular Permeability in Patients With ARDS (NCT04530188) | Bicetre Hospital | 2020-11-01 |
| Efficacy of Tranexamic Acid in Upper Gastrointestinal Bleeding (NCT04788121) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2020-11-01 |
| A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19 (NCT04540185) | Biomed Industries, Inc. | 2020-11-01 |
| Effects of Oral Magnesium Supplementation on Patients With Type 2 Diabetes (NCT04636411) | Samar Fares, MD | 2020-11-01 |
| Adjuvant Chemotherapy for High-risk Postenucleation Retinoblastoma (NCT05080010) | Sun Yat-sen University | 2020-11-01 |
| Carbon Ion RT for Locally Advanced Pancreatic Cancer (NCT04592861) | Albert Einstein College of Medicine | 2020-11-01 |
| SSI Rates in Patients Undergoing Mastectomy Without Reconstruction- A Multicenter, Double-blinded RCT. (NCT04577846) | Aga Khan University | 2020-11-01 |
| Alfacalcidol Supplementation on Levator Ani Muscle Strength of Menopausal Pelvic Organ Prolapse Patients (NCT05505253) | Universitas Padjadjaran | 2020-11-01 |
| A Study to Compare LY09004 and Eylea in the Treatment of Wet Age-related Macular Degeneration(wAMD) (NCT04572698) | Luye Pharma Group Ltd. | 2020-11-01 |
| PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome Patients (NCT04711434) | Sun Yat-sen University | 2020-11-01 |
| 18F-2-fluoro-2-deoxy-D-glucose in Positron Emission Tomography Computed Tomography (NCT04615156) | Eastern Health, Canada | 2020-11-01 |
| Primary Prophylaxis for Spontaneous Bacterial Peritonitis (NCT04775329) | Changi General Hospital | 2020-11-01 |
| PREFERENTIAL Study (NCT04563559) | Duke University | 2020-11-01 |
| Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver Disease (NCT05768334) | Helwan University | 2020-11-01 |
| Efficacy of 400 mg Efavirenz Versus Standard 600 mg Dose in HIV/TB Co-infected Patients (NCT04513379) | Shanghai Public Health Clinical Center | 2020-11-01 |
| Nebulised Heparin in Patients With Severe COVID-19 (NCT04545541) | Australian National University | 2020-11-01 |
| Proxalutamide Treatment for COVID-19 Female Outpatients (NCT04853134) | Applied Biology, Inc. | 2020-11-01 |
| Analgesic Efficacy of Dexmedetomidine as Adjuvant to Levobupivacaine in Ultrasound-guided Erector Spinae Plan Block for Modified Radical Mastectomy (NCT04732377) | South Egypt Cancer Institute | 2020-11-01 |
| NGA-01 Gel for the Treatment of Osteoarthritis With Joint Pain (NCT04612283) | Nutrin GmbH | 2020-10-31 |
| Study of the Commercial Scale SARS-CoV-2 Vaccine Against the Pilot Scale Among Adults, and Bridging Study of the Immunogenicity in Elderly Against That in Adults (NCT04617483) | Sinovac Research and Development Co., Ltd. | 2020-10-31 |
| Efficacy, Safety and Immunogenicity of Rotavirus RV3 Vaccine (Bio Farma) in Neonates (NCT04185545) | PT Bio Farma | 2020-10-30 |
| Pharmacodynamic Study Goserelin 3.6mg Injection Administered Subcutaneously in Premenopausal Patients with Breast Cancer (NCT03936933) | Eurofarma Laboratorios S.A. | 2020-10-30 |
| A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma (NCT04540211) | Hoffmann-La Roche | 2020-10-30 |
| TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS) (NCT04526951) | Oslo University Hospital | 2020-10-30 |
| Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial (NCT04472611) | Yale University | 2020-10-30 |
| Dose Escalation Study to Determine the Pharmacokinetics of Atazanavir Administered With RIfampicin to HIV Positive Adults on sEcond-line ART Regimen With Suppressed HIV-1 Viral Load (NCT04121195) | University of Liverpool | 2020-10-30 |
| A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010/LEAP-010)-China Extension (NCT05523323) | Merck Sharp & Dohme LLC | 2020-10-30 |
| Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT (NCT04560218) | Department of Medical Services Ministry of Public Health of Thailand | 2020-10-30 |
| Anakinra in the Management of COVID-19 Infection (NCT04643678) | Hamad Medical Corporation | 2020-10-30 |
| Treatment of PH With Angiotensin II Receptor Blocker and Neprilysin Inhibitor in HFpEF Patients With CardioMEMS Device (NCT04753112) | Germans Trias i Pujol Hospital | 2020-10-29 |
| Nintedanib for the Treatment of SARS-Cov-2 Induced Pulmonary Fibrosis (NCT04541680) | Assistance Publique - Hôpitaux de Paris | 2020-10-29 |
| Hypochlorous Acid Disinfection Prior to Cataract Surgery (NCT04568213) | Loma Linda University | 2020-10-29 |
| Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS) (NCT04577404) | Shionogi | 2020-10-29 |
| Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen (NCT04459117) | Institut National de la Santé Et de la Recherche Médicale, France | 2020-10-29 |
| Self-Management Program and Survivorship Care Plan in Improving the Health of Cancer Survivors After Stem Cell Transplant (NCT03125070) | Fred Hutchinson Cancer Center | 2020-10-29 |
| Electrocautery Ablation for the Prevention of Lung Cancer (NCT03870152) | University College, London | 2020-10-29 |
| Clinical Efficacy and Safety Evaluation of HCP1904-2 in Essential Hypertension Patients (NCT04830449) | Hanmi Pharmaceutical Company Limited | 2020-10-29 |
| A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous Pemphigoid (NCT04206553) | Regeneron Pharmaceuticals | 2020-10-28 |
| Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail (NCT04408313) | Friends Research Institute, Inc. | 2020-10-28 |
| A Pilot Study on the Use of Methoxyflurane (Penthrox®) for Pain Control in the Emergency Department (NCT04618497) | Hospital Authority, Hong Kong | 2020-10-28 |
| Sacituzumab Govitecan in Primary HER2-negative Breast Cancer (NCT04595565) | GBG Forschungs GmbH | 2020-10-28 |
| Timolol Maleate Gel for the Treatment of Infantile Hemangioma (NCT06677853) | Auson Pharmaceuticals Inc. | 2020-10-28 |
| Gleolan for Visualization of Newly Diagnosed or Recurrent Meningioma (NCT04305470) | NX Development Corp | 2020-10-28 |
| Tralokinumab in Combination With Topical Corticosteroids in Japanese Subjects With Moderate-to-severe Atopic Dermatitis (NCT04587453) | LEO Pharma | 2020-10-27 |
| Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections (NCT04579640) | Queen Mary University of London | 2020-10-27 |
| Randomized Trial in Adult Participants With Acute Migraines (NCT04571060) | Pfizer | 2020-10-27 |
| Early Prophylactic Low-molecular-weight Heparin (LMWH) in Symptomatic COVID-19 Positive Patients (NCT04492254) | Thrombosis Research Institute | 2020-10-27 |
| A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS (NCT04517253) | Eli Lilly and Company | 2020-10-27 |
| The Outcomes of Intracavernosal Umbilical Cord Mesenchymal Stem Cells Implantation in Patients With Diabetic Erectile Dysfunction (NCT04972890) | Indonesia University | 2020-10-27 |
| Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis (NCT04597775) | Regional Center for Disease Control and Prevention, Jordan | 2020-10-27 |
| Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin (NCT04452591) | CG Oncology, Inc. | 2020-10-27 |
| Clinical Efficacy and Safety Evaluation of HCP1904-1 in Essential Hypertension Patients (NCT04820907) | Hanmi Pharmaceutical Company Limited | 2020-10-27 |
| A Study of Sodium Oligomannate (GV-971) in Participants With Mild to Moderate Alzheimer's Disease (NCT04520412) | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | 2020-10-27 |
| Bicalutamide to Block TMPRSS2 in Males With COVID-19 Infection (NCT04509999) | University of Florida | 2020-10-26 |
| Placebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NCT04475939) | GlaxoSmithKline | 2020-10-26 |
| An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2) (NCT04599972) | Orasis Pharmaceuticals Ltd. | 2020-10-26 |
| Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases (NCT04410133) | Blue Earth Diagnostics | 2020-10-26 |
| A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis (NCT04544449) | Hoffmann-La Roche | 2020-10-26 |
| Comparison of Two Different Doses of Bemiparin in COVID-19 (NCT04604327) | Clinica Universidad de Navarra, Universidad de Navarra | 2020-10-26 |
| Efficacy and Safety of Rituximab in the Treatment of Good Prognosis Microscopic Polyangiitis (NCT03920722) | Assistance Publique - Hôpitaux de Paris | 2020-10-24 |
| Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients (NCT04188418) | M.D. Anderson Cancer Center | 2020-10-23 |
| Neoadjuvant FOLFOX Chemotherapy for Patients With Locally Advanced Colon Cancer (NCT03426904) | Kyungpook National University Hospital | 2020-10-23 |
| Canakinumab in Patients With COVID-19 and Type 2 Diabetes (NCT04510493) | University Hospital, Basel, Switzerland | 2020-10-23 |
| Phone-based Intervention Under Nurse Guidance After Stroke 2 (NCT04404166) | Northern California Institute of Research and Education | 2020-10-23 |
| Efficacy and Safety of Suvorexant (MK-4305) for Reducing Incidence of Delirium in Japanese Participants at High Risk of Delirium (MK-4305-085) (NCT04571944) | Merck Sharp & Dohme LLC | 2020-10-22 |
| Treatment for Moderate/Severe COVID-19 in a Fragile and Vulnerable Population, Admitted to a Geriatric Hospital Unit or in a Transicional Care Center (NCT04492358) | Maria Joyera Rodríguez | 2020-10-22 |
| Efficacy of Nicotine in Preventing COVID-19 Infection (NCT04583410) | Assistance Publique - Hôpitaux de Paris | 2020-10-22 |
| Efficacy and Safety of Acetylcysteine for the Treatment of Acute Uncomplicated Rhinosinusitis (NCT04123405) | Sandoz | 2020-10-22 |
| Safety and Efficacy Trial of BHV3000 (Rimegepant) 75 mg for the Acute Treatment of Migraine (NCT04574362) | Pfizer | 2020-10-22 |
| Triplet Combination of Cytotoxics as First-line Treatment for Metastatic Gastric Cancer (NCT04358354) | Sixth Affiliated Hospital, Sun Yat-sen University | 2020-10-22 |
| Phase 3 Study to Evaluate the Efficacy and Safety of Co-administrated AD-2021 and AD-2022 (NCT06448962) | Addpharma Inc. | 2020-10-22 |
| Venous Thromboembolism Prophylaxis After Gynecological Pelvic Cancer Surgery With Rivaroxaban vs Enoxaparin (NCT04999176) | André Luiz Malavasi Longo de Oliveira | 2020-10-22 |
| Drug Repurposing - Statins as Microbiota Modulating Agents in Ulcerative Colitis (NCT04883840) | Universitaire Ziekenhuizen KU Leuven | 2020-10-22 |
| A Multi-Center, Open-Label Long-Term Extension Study of CNM-Au8 In Patients With Stable Relapsing Multiple Sclerosis (NCT04626921) | Clene Nanomedicine | 2020-10-22 |