| Clinical Lot Consistency for RSVpreF in a Population of Healthy Adults 18 to ≤49 Years of Age (NCT05096208) | Pfizer | 2021-10-21 |
| Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS (NCT04708054) | M.D. Anderson Cancer Center | 2021-10-21 |
| A Study to Test the Efficacy, Safety and Tolerability of Romosozumab Treatment in Postmenopausal Chinese Women With Osteoporosis (NCT05067335) | UCB Biopharma SRL | 2021-10-21 |
| A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE) (NCT05113745) | Axsome Therapeutics, Inc. | 2021-10-20 |
| Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Laser-assisted in Situ Keratomileusis (LASIK) (NCT05082974) | Vance Thompson Vision ND | 2021-10-20 |
| Lasix for the Prevention of De Novo Postpartum Hypertension (NCT04752475) | Columbia University | 2021-10-20 |
| Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU) (NCT04859608) | University Hospital, Tours | 2021-10-20 |
| PARASTOP - Paracetamol With Strong Opioids (NCT05051735) | Oslo University Hospital | 2021-10-20 |
| Second-line Treatment of Primary Autoimmune Hemolytic Anemia (NCT05057468) | Assiut University | 2021-10-20 |
| Study to Assess Effectiveness and Adverse Events of JUVEDERM VOLBELLA With Lidocaine Injection in Correcting Infraorbital Hollowing in Chinese Adult Participants (NCT05088980) | Allergan | 2021-10-19 |
| A Study To Evaluate Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Patients With Generalized Myasthenia Gravis (NCT04963270) | Hoffmann-La Roche | 2021-10-19 |
| European Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata (NCT05041803) | Sun Pharmaceutical Industries, Inc. | 2021-10-19 |
| Low-dose Atropine for Myopia Control in Children (NCT03865160) | University Eye Hospital, Freiburg | 2021-10-19 |
| A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma (NCT05002569) | Bristol-Myers Squibb | 2021-10-19 |
| A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC) (NCT04779307) | Takeda | 2021-10-19 |
| Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain (NCT04809376) | Paradigm Biopharmaceuticals USA (INC) | 2021-10-19 |
| A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 1) (NCT05066997) | Oculis | 2021-10-19 |
| Single-agent Capecitabine as Metronomic Chemotherapy in LAHNSCC (CMHN) (NCT05044117) | Sun Yat-sen University | 2021-10-18 |
| The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients (Phase3) (NCT05084911) | Shin Poong Pharmaceutical Co. Ltd. | 2021-10-18 |
| Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use (NCT06770114) | Colgate Palmolive | 2021-10-18 |
| A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01) (NCT05104866) | AstraZeneca | 2021-10-18 |
| Efficacy and Safety of LXI-15028 Comparing With Lansoprazole in the Treatment of Duodenal Ulcer (NCT05010954) | Shandong Luoxin Pharmaceutical Group Stock Co., Ltd. | 2021-10-18 |
| Study to Investigate the Efficacy and Safety of FAB122 (Daily Oral Edaravone) in Patients With Amyotrophic Lateral Sclerosis (NCT05178810) | Ferrer Internacional S.A. | 2021-10-18 |
| A Long-term Extension Study of Ustekinumab in Pediatric Participants (NCT05092269) | Janssen Research & Development, LLC | 2021-10-18 |
| a Phase III Trial of Safety and Efficacy of Premedication With Dexmedetomidine and Midazolam in Pediatric Patients (NCT04356638) | King Faisal Specialist Hospital & Research Center | 2021-10-17 |
| Ahmed Valve Implantation Coated With Poly Lactic -Co-glycolic Acid (PLGA) Saturated With Mitomycin-C in the Management of Adult Onset Glaucoma in Sturge Weber Syndrome (NCT04735601) | Sohag University | 2021-10-15 |
| Comparing Efficacy of Azithromycin and Probiotics for Treatment of Acne Vulgaris (NCT05629468) | Pak Emirates Military Hospital | 2021-10-15 |
| Double-blind Comparative Randomized Multicenter (NCT06840158) | Innopharm LLC | 2021-10-15 |
| Сlinical Trial of Efficacy and Safety of Prospekta in the Treatment of Post-COVID-19 Asthenia. (NCT05074888) | Materia Medica Holding | 2021-10-15 |
| Open-Label Study to Evaluate the Safety and Efficacy of Avatrombopag and Remission Rates in Adults With ITP of ≤6 Months (NCT05046327) | Sobi, Inc. | 2021-10-14 |
| A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients. (NCT03998319) | University of Sydney | 2021-10-14 |
| A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy (NCT04455750) | Alliance for Clinical Trials in Oncology | 2021-10-14 |
| Alternative Antibiotics for Syphilis (NCT05069974) | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 2021-10-14 |
| Study of Vimseltinib for Tenosynovial Giant Cell Tumor (NCT05059262) | Deciphera Pharmaceuticals, LLC | 2021-10-14 |
| Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx (NCT04935177) | Hansa Biopharma AB | 2021-10-14 |
| A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (NCT05083169) | Janssen Research & Development, LLC | 2021-10-14 |
| Study to Assess the Efficacy and Safety of Garetosmab in Japanese Adult Patients With Fibrodysplasia Ossificans Progressiva (FOP) (NCT04577820) | Regeneron Pharmaceuticals | 2021-10-13 |
| Effectiveness of Periocular Drug Injection in CATaract Surgery (NCT05158699) | Luigi Rondas | 2021-10-13 |
| Asciminib Treatment Optimization in ≥ 3rd Line CML-CP (NCT04948333) | Novartis Pharmaceuticals | 2021-10-13 |
| Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal (FAI) Insert (NCT05070728) | EyePoint Pharmaceuticals, Inc. | 2021-10-13 |
| A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF) (NCT04969224) | Vertex Pharmaceuticals Incorporated | 2021-10-12 |
| Eosinophil-driven Corticotherapy for Patients Hospitalized for COPD Exacerbation (NCT04234360) | University Hospital, Montpellier | 2021-10-12 |
| The Effect of Eplerenone on the Evolution of Vasculopathy in Renal Transplant Patients. (NCT04450953) | Central Hospital, Nancy, France | 2021-10-12 |
| A Study to Evaluate an Updated Dexamethasone Intravitreal (Into the Eye) Applicator in Adult Participants With Macular Edema Due to Diseases of the Retina (NCT04976777) | AbbVie | 2021-10-12 |
| Efficacy Evaluation of Enobosarm Monotherapy in Treatment of AR+/ER+/HER2- Metastatic Breast Cancer (NCT04869943) | Veru Inc. | 2021-10-12 |
| A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment(SUPER-2) (NCT04998032) | Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. | 2021-10-12 |
| Improvement in the Appearance of Periorbital Wrinkles (NCT05082766) | Goldman, Butterwick, Fitzpatrick and Groff | 2021-10-11 |
| The Hemophilia Inhibitor Prevention Trial (NCT04303559) | Margaret Ragni | 2021-10-11 |
| Clinical Study of Clevidipine Butyrate Injection in the Treatment of Hypertensive Emergency and Sub-emergency (NCT05044364) | Shenzhen People's Hospital | 2021-10-11 |
| Adipose-derived Stem Cell Conditioned Media as a Novel Approach for Hair Regrowth in Male Androgenetic Alopecia (NCT05296863) | Dr. dr. Lili Legiawati, SpKK(K) | 2021-10-11 |
| Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis (NCT04973670) | Southeast University, China | 2021-10-11 |
| Does Electrocautery Increase Postoperative Pain in Primary Total Knee Arthroplasty (NCT06239038) | Police General Hospital, Thailand | 2021-10-11 |
| Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode (NCT03646058) | Centre Hospitalier Universitaire de Nīmes | 2021-10-10 |
| Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin (NCT06595355) | Isfahan University of Medical Sciences | 2021-10-10 |
| Lidocaine Patches After Cesarean Section (NCT04443569) | Yale University | 2021-10-10 |
| Effect of Pre-emptive Intravenous Immunoglobulin (IVIG) on the Incidence of Septic Episodes in Pediatric Burn Patients (NCT05134792) | Cairo University | 2021-10-10 |
| Direct Oral Anticoagulants for Prevention of lEft ventRIcular Thrombus After Anterior Acute Myocardial InFarction - APERITIF (NCT05077683) | Assistance Publique - Hôpitaux de Paris | 2021-10-10 |
| Obeticholic Acid Versus Placebo, in Combination with Ursodeoxycholic Acid in Patients with Primary Biliary Cirrhosis (NCT06715319) | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | 2021-10-09 |
| Intermediate Dose of IV MTX as CNS Prophylaxis for High Risk DLBCL (NCT05054426) | Peking Union Medical College Hospital | 2021-10-08 |
| A Study to Evaluate Immunogenicity and Safety of MVC-COV1901 Compared With AZD1222 Against COVID-19 in Adults (NCT05011526) | Medigen Vaccine Biologics Corp. | 2021-10-08 |
| An Open-label Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder (NCT05061719) | Intra-Cellular Therapies, Inc. | 2021-10-08 |
| A Study Evaluating the Immunogenicity of Different Clinical Trial Materials of Ad26.RSV.preF- Based Vaccine in Adults Aged 60 - 75 Years Old (NCT05083585) | Janssen Vaccines & Prevention B.V. | 2021-10-08 |
| Phase 3 Booster Vaccination Against COVID-19 (NCT05077176) | Health Institutes of Turkey | 2021-10-08 |
| Adjuvant Chemotherapy of Three-step Regimen in BRCA1/2 Wide Type Ovarian Cancer (ACTS-2) (NCT04520074) | Fudan University | 2021-10-08 |
| A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or Following a COVID-19 Booster Vaccine (NCT05047770) | GlaxoSmithKline | 2021-10-07 |
| Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (NCT05040126) | Tuberculosis Research Centre, India | 2021-10-07 |
| MYTHS - MYocarditis THerapy With Steroids (NCT05150704) | Niguarda Hospital | 2021-10-07 |
| Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel (NCT04862585) | Ohio State University Comprehensive Cancer Center | 2021-10-07 |
| Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Giant Cell Arteritis (GCA) (NCT04930094) | Novartis Pharmaceuticals | 2021-10-06 |
| Analgesic Ear Drops for Children With Acute Otitis Media (NCT05651633) | UMC Utrecht | 2021-10-06 |
| Combined Intravitreal Bevacizumab With Topical Timolol-Dorzolamide Eye Drops in Diabetic Macular Edema (NCT05083689) | Shahid Beheshti University of Medical Sciences | 2021-10-06 |
| Immune Non-Inferiority, Safety and Lot-to-Lot Consistency of Oral Cholera Vaccine-Simplified Compared to Shanchol™ (NCT04760236) | International Vaccine Institute | 2021-10-06 |
| Hypnosis Intervention for the Management of Pain Perception During Joint Lavage (NCT04547595) | Assistance Publique - Hôpitaux de Paris | 2021-10-06 |
| Efficacy and Safety Study of rhTSH for Adjuvant Radioiodine Ablation Therapy in Patients With Differentiated Thyroid Cancer (NCT04964284) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2021-10-06 |
| Imaging for the Evaluation of Transthyretin Cardiac Amyloidosis Prevalence of Patients Over 65 Hospitalized in Cardiology Wards (the IMPACT Study) (NCT05064839) | Poitiers University Hospital | 2021-10-06 |
| A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP (NCT04971226) | Novartis Pharmaceuticals | 2021-10-06 |
| Efficacy and Safety of Ingavirin®, 90 mg Capsules in Patients With COVID-19 (NCT05216497) | Valenta Pharm JSC | 2021-10-06 |
| Efficacy and Safety of Ergoferon for COVID-19 Prevention During Vaccination Against SARS-CoV-2 (NCT05069649) | Materia Medica Holding | 2021-10-06 |
| Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma (NCT04759586) | National Cancer Institute (NCI) | 2021-10-05 |
| Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis (NCT04926818) | Novartis Pharmaceuticals | 2021-10-05 |
| Use of an Investigational Digital Therapeutic in Patients With Type 2 Diabetes (NCT05094401) | Better Therapeutics | 2021-10-04 |
| A Study of an Ad26.RSV.preF-based Vaccine and High-dose Seasonal Influenza Vaccine, With and Without Coadministration, in Adults Aged 65 Years and Older (NCT05071313) | Janssen Vaccines & Prevention B.V. | 2021-10-04 |
| A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments (NCT05020236) | Pfizer | 2021-10-04 |
| A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer (NCT04975308) | Eli Lilly and Company | 2021-10-04 |
| A Comparative Study Between ABP 501 and Humira® in Participants With Moderate to Severe Plaque Psoriasis (NCT05073315) | Amgen | 2021-10-04 |
| A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises (NCT04935879) | Pfizer | 2021-10-04 |
| Effect of Cholecalciferol Supplementation on Disease Activity and Quality of Life of Systemic Lupus Erythematosus Patients . (NCT05326841) | Dr Cipto Mangunkusumo General Hospital | 2021-10-03 |
| "Prevention of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients" (NCT05189535) | Ain Shams University | 2021-10-03 |
| Comparison Between RCT in Single and Two Visits, With and Without Intracanal Dressing, in Apical Repair (NCT05256667) | New York University | 2021-10-02 |
| Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% to LUMIGAN® In The Treatment of Chronic Open-Angle Glaucoma (NCT04890106) | Mankind Pharma Limited | 2021-10-02 |
| Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis (NCT05064735) | Novo Nordisk A/S | 2021-10-01 |
| Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years (NCT05846243) | Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector" | 2021-10-01 |
| Chinese Herbal Medicine in Acute INtracerebral Haemorrhage (CHAIN) Trial (NCT05066620) | Guangzhou University of Traditional Chinese Medicine | 2021-10-01 |
| Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus (NCT04817215) | King Hamad University Hospital, Bahrain | 2021-10-01 |
| Efficacy, Immunogenicity and Safety of BBIBP-CorV Vaccine Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection. (NCT04984408) | International Vaccine Institute | 2021-10-01 |
| Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury. (NCT05008484) | VA Office of Research and Development | 2021-10-01 |
| COVID-19: A Trial Studying the SARS-CoV-2 mRNA Vaccine CVnCoV to Learn About the Immune Response, the Safety, and the Degree of Typical Vaccination Reactions When CVnCoV is Given at the Same Time as a Flu Vaccine Compared to When the Vaccines Are Separately Given in Adults 60 Years of Age and Older (NCT04848467) | Bayer | 2021-10-01 |
| Tucidinostat, Azacitidine Combined With CHOP Versus CHOP in Patients With Untreated Peripheral T-cell Lymphoma (NCT05075460) | Peking Union Medical College Hospital | 2021-10-01 |
| Hydroxychloroquine in Isolated Cutaneous Mastocytosis Patients or Indolent Systemic Mastocytosis With Associated Skin Involvement Patients (NCT05084872) | University Hospital, Toulouse | 2021-10-01 |
| Efficacy and Biomarker Development for Lung Cancer Treated With Immune Checkpoint Inhibitors (NCT05055908) | Hunan Province Tumor Hospital | 2021-10-01 |