| Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa (NCT06834035) | M. Peter Marinkovich | 2025-08-04 |
| Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in Adolescent Females With Type 1 Diabetes Mellitus (NCT07319286) | Ain Shams University | 2025-08-04 |
| Response-adaptive to Epcoritamab In First Relapse: Study to Evaluate the Efficacy of Eptoritamab in Patients With Relapse/Refractory Large B Cell Lymphoma (NCT07126236) | Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea | 2025-08-04 |
| A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer (NCT07005102) | AbbVie | 2025-08-03 |
| 177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia (NCT07025512) | M.D. Anderson Cancer Center | 2025-08-03 |
| Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK) (NCT07095842) | Sohag University | 2025-08-03 |
| Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff Pressure (NCT07315490) | PAEC General Hospital, Islamabad | 2025-08-02 |
| Evaluate the Long-term Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia (NCT07133815) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2025-08-01 |
| 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer (NCT06298916) | Lantheus Medical Imaging | 2025-08-01 |
| A Prospective, Multicenter Clinical Study of Hetrombopag in the Prevention of Thrombocytopenia Caused by Lung Cancer Therapy (NCT07101627) | Shanghai Pulmonary Hospital, Shanghai, China | 2025-08-01 |
| A Study of Disitamab Vedotin + Bicalutamide in HER2/AR-Positive Scrotal Paget's Disease (NCT07117851) | Fudan University | 2025-08-01 |
| Tranexamic Acid : Nebulization vs IV Route for Hemoptysis (NCT07212452) | University of Health Sciences Lahore | 2025-08-01 |
| Oral Changes With Caloric and no Caloric Sweeteners (NCT05852145) | Hospital Infantil de Mexico Federico Gomez | 2025-08-01 |
| Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease (NCT06919081) | University of Illinois at Chicago | 2025-08-01 |
| Organoid-guided vs Topotecan Therapy in Relapsed Extensive-Stage Small Cell Lung Cancer (NCT07106528) | Peking Union Medical College Hospital | 2025-08-01 |
| Clinical Study of Thiopegfilgrastim for Preventing Bone Marrow Suppression in Thoracic Tumor Chemoradiotherapy (NCT07205536) | Affiliated Hospital of Nantong University | 2025-08-01 |
| SHR-1811 Combined With Carboplatin in the Treatment of Advanced Breast Cancer With HER2 Expression (NCT07047443) | Anhui Provincial Cancer Hospital | 2025-08-01 |
| Phase 2a Study for PK/PD of nC-001 (NCT06798675) | nephCentric | 2025-08-01 |
| The Efficacy and Safety of Puerarin in Obesity Treatment (NCT06968208) | Ruijin Hospital | 2025-08-01 |
| Comparing the Combination of Trastuzumab and Regorafenib With Regorafenib Monotherapy for Advanced Hepatocellular Carcinoma After First-line Treatment (NCT07078305) | Tianjin Medical University Cancer Institute and Hospital | 2025-08-01 |
| Anti-CD38 Antibody Treating Elderly Patients With Primary Immune Thrombocytopenia (ITP) (NCT07063199) | Institute of Hematology & Blood Diseases Hospital, China | 2025-08-01 |
| Study of TYK-00540 Combined With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer（mCRPC） (NCT07104643) | TYK Medicines, Inc | 2025-08-01 |
| 9MW2821 Combined With Toripalimab in Perioperative Patients With Urothelial Cancer (NCT07314723) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2025-08-01 |
| Camrelizumab in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-negative Breast Cancer (NCT07107217) | Blokhin's Russian Cancer Research Center | 2025-08-01 |
| Reduced Intensity Conditioning for MDS (NCT07085156) | Ruijin Hospital | 2025-08-01 |
| Tislelizumab Combined With Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma Followed by CRT or Surgery (NCT07046221) | Fujian Cancer Hospital | 2025-08-01 |
| A Phase II, Single-Arm, Prospective Trial on the Efficacy and Safety of QL1706 Combination Regimen as Second-Line Therapy for Targeted-Immunotherapy-Resistant Hepatocellular Carcinoma (NCT07138885) | Sun Yat-sen University | 2025-08-01 |
| Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder (NCT06559995) | University of Pennsylvania | 2025-08-01 |
| Gentian Violet Treatment for Hidradenitis Suppurativa (NCT04388163) | Wake Forest University Health Sciences | 2025-08-01 |
| Senicapoc in Patients With Worsening Fibrotic Interstitial Lung Disease (NCT06714123) | Vejle Hospital | 2025-08-01 |
| A Phase II/III Study of IBB0979 in Combination With Topotecan Versus Topotecan in Relapsed Small Cell Lung Cancer (NCT07076095) | SUNHO（China）BioPharmaceutical CO., Ltd. | 2025-08-01 |
| Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC (NCT07098988) | CatalYm GmbH | 2025-08-01 |
| An Open-label Single Center, Proof of Concept Study Evaluating the Efficacy of Roflumilast Foam 0.3% in Pediatric Patients With Non-Segmental Vitiligo (NSV) (NCT07105254) | Derm Texas, PLLC | 2025-08-01 |
| A Study Evaluating the Efficacy and Safety of RCI001 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (NCT07068958) | ORA, Inc. | 2025-08-01 |
| Effect of Baclofen in Management of Patients With Gastroesophageal Reflux Disease Symptoms (NCT07063576) | Adnan Imtiaj Rahul | 2025-08-01 |
| Tislelizumab , Cyclophosphamide, Mitoxantrone Liposomes, Chidamide, and Prednisone in the Treatment of New Diagnosed AITL (NCT07168317) | The Affiliated Hospital of Xuzhou Medical University | 2025-08-01 |
| Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT) (NCT07462260) | Sindh Institute of Cardiovascular Diseases | 2025-08-01 |
| KANGFUPEN Liquid Dressing for Chronic Radiation-Induced Rectal Injury (NCT07065175) | Peking Union Medical College Hospital | 2025-08-01 |
| A Phase II Study of QL1706 With Anti-angiogenesis Therapy and Chemotherapy in Extensive-stage Small Cell Lung Cancer. (NCT07083375) | Zhijie Wang | 2025-08-01 |
| Safety and Efficacy of Oral Artesunate for Pre-cervical Cancer (NCT07095478) | Metanoic Health Ltd. | 2025-08-01 |
| Chamomile Gummies and Pediatric Dental Anxiety (NCT07138391) | Ain Shams University | 2025-08-01 |
| Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma (NCT06356883) | Université de Sherbrooke | 2025-08-01 |
| Virtual Reality for Pain and Anxiety Relief During Peripheral Angioplasty (NCT07057752) | Kastamonu University | 2025-08-01 |
| Phase 2 Clinical Trial of KH617 (NCT07138001) | Sichuan Honghe Biotechnology Co., Ltd. | 2025-08-01 |
| Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers (NCT07087860) | Mayo Clinic | 2025-08-01 |
| Tislelizumab Combined With Thoracic Radiotherapy as Neoadjuvant Therapy for Resectable NSCLC (NCT07050056) | Northern Jiangsu People's Hospital | 2025-08-01 |
| QL1706/Bevacizumab ± Chemotherapy in Post-ICI Non-Squamous NSCLC (NCT07134413) | Guangdong Association of Clinical Trials | 2025-08-01 |
| A Randomized, Two-cohort, Prospective Phase II Clinical Study of the Second-line Treatment of Advanced Biliary System Tumors With Liposomal Irinotecan (II) Combination Regimen (NCT07099794) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-08-01 |
| Gingival Hyperpigmentation Treatment (NCT07595705) | Cairo University | 2025-08-01 |
| Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the Endometrium (NCT06073184) | University Health Network, Toronto | 2025-08-01 |
| Toripalimab Combined With Chemotherapy as Adjuvant Therapy for Incidental Small Cell Lung Cancer After Radical Resection of Lung Cancer: A Single-Center, Randomized Controlled Clinical Study Protocol Number: LungMate-033 (NCT07097948) | Shanghai Pulmonary Hospital, Shanghai, China | 2025-08-01 |
| Study of ZG006 in Participants With Neuroendocrine Prostate Cancer (NCT07024277) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2025-08-01 |
| Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) (NCT06948019) | BlackfinBio Ltd | 2025-08-01 |
| Phase II Trial of BrECADD in HIV-Positive Patients With Advanced-Stage Classical Hodgkin Lymphoma (NCT06919679) | University of Cologne | 2025-08-01 |
| Ivonescimab (PD-1/VEGF Bispecific Antibody) Plus Radiofrequency Ablation for Multiple Advanced Tumors After PD-1 Therapy Failure (NCT07095803) | Sheng Zhang | 2025-08-01 |
| A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy) (NCT06557460) | Regenerative Patch Technologies, LLC | 2025-08-01 |
| An Open-Label Study of Effectiveness of Immunomodulatory Medications for Patients With Relapsing Polychondritis (NCT06941376) | University of Pennsylvania | 2025-08-01 |
| Efficacy Study of Digoxin Combined With Serplulimab and Chemotherapy in First-Line Treatment of MSS Advanced Colorectal Cancer (NCT07025850) | Fudan University | 2025-08-01 |
| Exploring a Natural Solution for Childhood Obesity (NCT07033767) | Western University | 2025-08-01 |
| The Safety and Efficacy of Benmelstobart Injection in Patients With Advanced Biliary Tract Malignant Tumors (NCT07109167) | The Second Affiliated Hospital of Shandong First Medical University | 2025-08-01 |
| PD-1 Inhibitor Therapy Versus Radiotherapy in MPR Patients With Locally Advanced HNSCC After Neoadjuvant Immunochemotherapy (HNC-SYSU-006) (NCT07090707) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2025-08-01 |
| ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer (NCT06970912) | Peking University People's Hospital | 2025-08-01 |
| Efficacy and Safety of Simultaneous Integrated Boost Radiotherapy in HR/VHR Prostate Cancer With EPLNI (NCT07693075) | Ain Shams University | 2025-08-01 |
| Exploration of Manidipine to Reverse Aortic Valve Calcification (NCT07091136) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-08-01 |
| A Phase II Study to Evaluate GFH375 in Patients With KRAS G12D Mutant Metastatic Pancreatic Cancer (NCT07026916) | Genfleet Therapeutics (Shanghai) Inc. | 2025-08-01 |
| Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine (NCT07185815) | Mapi Pharma Ltd. | 2025-08-01 |
| Autologous Hematopoietic Stem Cell Infusion for Prolonged Cytopenia After CAR-T Cell Therapy (NCT07127289) | Institute of Hematology & Blood Diseases Hospital, China | 2025-08-01 |
| A Tumor Immune Biomarker Guided Approach for Improving Response to BCG in Patients With High-risk NMIBC. (NCT07064863) | Queen's University | 2025-08-01 |
| A Phase I/II Clinical Study of FH-006 for Injection in Patients With Malignant Solid Tumors (NCT07136142) | Jiangsu HengRui Medicine Co., Ltd. | 2025-08-01 |
| Pharmacokinetic and Safety Study of Metronidazole Oral Suspension in Pediatric Patients With Anaerobic Bacterial Infection (NCT07146217) | Saptalis Pharmaceuticals LLC | 2025-08-01 |
| Effectiveness and Safety of Blinatumomab and Donor Lymphocyte Infusion in Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation for High-risk Ph Negative B Cell Acute Lymphoblastic Leukemia (NCT07105579) | First Affiliated Hospital of Zhejiang University | 2025-08-01 |
| Autologous Neoantigen-Specific T-Cell Therapy for Advanced Hepatocellular Carcinoma (NCT07123545) | Zhejiang University | 2025-08-01 |
| Combination CAR-T Cell Therapy Targeting Hematological Malignancies (NCT03125577) | Shenzhen Geno-Immune Medical Institute | 2025-08-01 |
| Exploration of Treatment Effect of Novel Hormone Therapy Combined With Local Treatment Based on PSMA PET/CT Evaluation in mHSCP Patients (NCT06832774) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2025-08-01 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VT7208 in Healthy Participants and MS Patients (NCT07085507) | Vidya Therapeutics Inc | 2025-08-01 |
| Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis (NCT07307989) | Chang Gung Memorial Hospital | 2025-08-01 |
| Evaluating the Efficacy of Hyperthermic Intraperitoneal Treatment to Enhance the Sensitivity of Immune Checkpoint Inhibitor in Patients With Advanced Ovarian Cancer： A Single-arm Study (NCT07068178) | Jing Li | 2025-08-01 |
| Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory Trial (NCT07118059) | North-West University, South Africa | 2025-08-01 |
| Phase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord Injury (NCT06677229) | Technophage, SA | 2025-08-01 |
| JDB153 Combined With Penpulimab for Hepatocellular Carcinoma After Standard Treatment Failure (NCT07075419) | West China Hospital | 2025-08-01 |
| A Study on the Safety and Efficacy of TQB3473 Tablets in the Treatment of Persistent or Chronic Primary Immune Thrombocytopenia (ITP) in Adults (NCT07083739) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2025-08-01 |
| Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of Recurrence (NCT06954116) | Tongji Hospital | 2025-08-01 |
| Comparing the Combination of Sullumab and Fruquintinib in Postoperative Adjuvant Therapy for High Recurrence Risk Non Transparent Renal Cell Carcinoma (NCT07488533) | Sun Yat-sen University | 2025-08-01 |
| Efficacy and Safety of VAH as a Bridging Regimen to Allo-HCT in Relapsed/Refractory AML (NCT07091006) | Ruijin Hospital | 2025-08-01 |
| Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer (NCT07154316) | Fudan University | 2025-08-01 |
| Iparomlimab and Tuvonralimab Combined With 2 or 4 Cycles of Chemotherapy as Neoadjuvant Therapy for Resectable NSCLC (NCT07129161) | Sun Yat-sen University | 2025-08-01 |
| Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer (NCT07182279) | The Methodist Hospital Research Institute | 2025-08-01 |
| Autologous Adipose Cells Therapy (NCT06869252) | CERM INC. | 2025-08-01 |
| Oncolytic Virus in Esophageal Squamous Cell Carcinoma (NCT07061704) | Sichuan University | 2025-08-01 |
| Study of TY-302 Capsules Combined With Abiraterone in Patients With Metastatic Castration-resistant Prostate Cancer（mCRPC） (NCT07104617) | TYK Medicines, Inc | 2025-08-01 |
| A Clinical Study to Evaluate the Safety and Pharmacokinetics of Topical RSS0393 Ointment in Children and Adolescents With Plaque Psoriasis (NCT07102888) | Jiangsu HengRui Medicine Co., Ltd. | 2025-08-01 |
| Activated Charcoal Use in Chronic Kidney Disease Patients (NCT06906874) | Mansoura University | 2025-08-01 |
| Lactoferrin Supplementation in Diabetic Nephropathy (NCT07764991) | Ain Shams University | 2025-08-01 |
| Study of Sivelestat Sodium in OPCABG (NCT07118930) | Affiliated Hospital of Nantong University | 2025-08-01 |
| Multiple CAR-T Cell Therapy Targeting AML (NCT04010877) | Shenzhen Geno-Immune Medical Institute | 2025-08-01 |
| Romiplostim N01 for Chemotherapy-induced Thrombocytopenia (NCT07063225) | Institute of Hematology & Blood Diseases Hospital, China | 2025-08-01 |
| Safety and Efficacy of Radiotherapy Combined with Immunotherapy for Advanced Malignant Tumors. (NCT06173219) | China-Japan Friendship Hospital | 2025-08-01 |
| Study Evaluating the Efficacy and Safety of Artesunate (NCT06853184) | Amivas Inc. | 2025-08-01 |
| Intervention of Bladder Cancer by CAR-T (NCT03185468) | Shenzhen Geno-Immune Medical Institute | 2025-08-01 |
| Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease (NCT07369063) | Northwell Health | 2025-08-01 |