| Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A) (NCT04626479) | Merck Sharp & Dohme LLC | 2020-12-16 |
| Safety and Effectivness of Quercetin & Dasatinib on Epigenetic Aging (NCT04946383) | TruDiagnostic | 2020-12-16 |
| Lamotrigine and Bupropion for Meniere's Disease (NCT05420350) | Dent Neuroscience Research Center | 2020-12-16 |
| Regorafenib Plus Tislelizumab as First-line Systemic Therapy for Patients With Advanced Hepatocellular Carcinoma (NCT04183088) | National Taiwan University Hospital | 2020-12-16 |
| XC8 in the Treatment of Patients With the Eosinophilic Phenotype of Bronchial Asthma (NCT04674137) | Chemlmmune Therapeutics LLC | 2020-12-16 |
| Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD) (NCT04443348) | Laura M. Spring, MD | 2020-12-16 |
| Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 (NCT04659109) | Acticor Biotech | 2020-12-16 |
| Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS) (NCT04358133) | Assistance Publique - Hôpitaux de Paris | 2020-12-16 |
| The Efficacy of JS001 Combined With Chemotherapy in Patients With Locally Advanced Colon Cancer (NCT03985891) | Xiangya Hospital of Central South University | 2020-12-16 |
| A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 (NCT04640194) | Boehringer Ingelheim | 2020-12-16 |
| Dose Finding Study to Evaluate The Safety, Tolerability and Immunogenicity of an Inactiviated, Adjuvanted SARS-CoV-2 Virus Vaccine Candidate Against Covid-19 in Healthy Subjects (NCT04671017) | Valneva Austria GmbH | 2020-12-16 |
| Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities (NCT04683250) | Taiho Pharmaceutical Co., Ltd. | 2020-12-16 |
| SYMPHONY-2, A Trial to Examine Combination of Tazemetostat With Rituximab in Subjects With Relapsed/Refractory Follicular Lymphoma (NCT04762160) | Epizyme, Inc. | 2020-12-15 |
| Gallium Ga 68 DOTA-NeoBOMB1 and Gallium Ga 68 PSMA-R2 PET/MRI in Diagnosing Participants With Recurrent Prostate Cancer (NCT03698370) | Andrei Iagaru | 2020-12-15 |
| Fecal Microbiome Transplantation (FMT) in Pediatric Patients Colonized With Antibiotic-resistant Pathogens Before Hematopoietic Stem Cell Transplantation (HSCT) (NCT04593368) | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 2020-12-15 |
| Low-Dose Pioglitazone in Patients With NASH (AIM 2) (NCT04501406) | University of Florida | 2020-12-15 |
| Induction of Transplant Tolerance in LDLT Via iTS (NCT04950842) | Juntendo University | 2020-12-15 |
| A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis (NCT04682639) | Pfizer | 2020-12-15 |
| Study of SC10914 in Patients With gBRCA1/2 Mutation Advanced Ovarian Cancer (NCT04556539) | Jiangxi Qingfeng Pharmaceutical Co. Ltd. | 2020-12-15 |
| LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors (NCT04666688) | PureTech | 2020-12-15 |
| Efficacy and Safety of Elpipodect (MK-8189) in Participants With an Acute Episode of Schizophrenia (MK-8189-008) (NCT04624243) | Merck Sharp & Dohme LLC | 2020-12-15 |
| A Combination Efficacy Study in Africa of Two DNA-MVA-Env Protein or DNA-Env Protein HIV-1 Vaccine Regimens With PrEP (NCT04066881) | MRC/UVRI and LSHTM Uganda Research Unit | 2020-12-15 |
| CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops (NCT04843839) | L.V. Prasad Eye Institute | 2020-12-15 |
| A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Participants With Previously Untreated Advanced Non-Squamous Non-Small Cell Lung Cancer (NCT04619797) | Hoffmann-La Roche | 2020-12-15 |
| Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder (NCT04352166) | Frances R Levin | 2020-12-15 |
| Photobiomodulation Effect on Vulvovaginal Atrophy in Postmenopausal Women. (NCT04487392) | University of Nove de Julho | 2020-12-15 |
| A Study of the Combination of Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (NCT04586426) | Janssen Research & Development, LLC | 2020-12-15 |
| Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH (NCT04702490) | Metacrine, Inc. | 2020-12-15 |
| Conversion Therapy of Camrelizumab Plus Chemoradiotherapy in Participants With Initial Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (NCT04631757) | Tianjin Medical University Cancer Institute and Hospital | 2020-12-15 |
| Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD (NCT04626128) | Clearside Biomedical, Inc. | 2020-12-15 |
| Ablation Combined With PD-1 in HCC: Phase II Study (NCT04652440) | Sun Yat-sen University | 2020-12-15 |
| COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection (NCT04666441) | Regeneron Pharmaceuticals | 2020-12-15 |
| Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin Toxicity (NCT04631731) | Western Sydney Local Health District | 2020-12-15 |
| A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy (NCT04354727) | Ascentage Pharma Group Inc. | 2020-12-15 |
| DiaBetter Together for Young Adults With Type 1 Diabetes (NCT04247620) | Baylor College of Medicine | 2020-12-15 |
| PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence (NCT04787341) | Gruppo Oncologico del Nord-Ovest | 2020-12-15 |
| To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL) (NCT04661007) | Incyte Biosciences Japan GK | 2020-12-15 |
| Study Evaluating Near-infrared Imaging Coupled With Indocyanine Green for Intraoperative Control of Resection Margins in ENT Surgery (NCT04842162) | Gustave Roussy, Cancer Campus, Grand Paris | 2020-12-15 |
| Depressed Mood Improvement Through Nicotine Dosing 2 (NCT04433767) | Vanderbilt University Medical Center | 2020-12-15 |
| Albumin-bound Paclitaxel Combination With Capecitabine Versus Capecitabine Monotherapy in Paclitaxel/Docetaxel-resistant Advanced Breast Cancer (NCT04780347) | Fudan University | 2020-12-15 |
| Sorafenib Maintenance for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3 Negative Acute Leukemia (NCT04674345) | Nanfang Hospital, Southern Medical University | 2020-12-15 |
| Acalabrutinib, Umbralisib, and Ublituximab (AU2) In Relapsed and Untreated CLL (NCT04624633) | Jennifer R. Brown, MD, PhD | 2020-12-15 |
| Fasudil fOr redUcing elopemeNt and Spatial Disorientation (NCT04793659) | Woolsey Pharmaceuticals | 2020-12-15 |
| To Evaluate the Efficacy and Safety of TG-1000 Compared With Placebo in Adult Patients With Acute Uncomplicated Influenza Virus Infection (NCT04706468) | TaiGen Biotechnology Co., Ltd. | 2020-12-15 |
| An Efficacy, Immunogenicity and Safety Study Investigating an Adjuvanted SARS-CoV-2 Influenza Vaccine to Protect Against COVID-19 in Adults Over Aged 18 Years-old and Older (NCT04806529) | Seqirus | 2020-12-15 |
| Clinical and Metabonomics Study on the Treatment of Heart Failure After Myocardial Infarction With Modified Wenxin Decoction (NCT04667598) | Jun Li | 2020-12-15 |
| Bonipar for Acute and Chronic Musculoskeletal Pain (NCT03471507) | Winston Parris, MD | 2020-12-15 |
| Durvalumab and Tremelimumab in Combination With Y-90 SIRT for Intermediate Stage HCC (NCT04522544) | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | 2020-12-15 |
| Efficacy and Safety of Norketotifen in Uncomplicated Influenza-like Illness (NCT04610047) | Emergo Therapeutics, Inc. | 2020-12-14 |
| Effect of Inhaled Aromatherapy on Chemo-Induced Nausea Vomiting (NCVI): CINVAROM (Chemotherapy Induced Nausea Vomiting and AROMatherapy) (NCT04560114) | Centre Francois Baclesse | 2020-12-14 |
| BT200 in Hereditary Bleeding Disorders (NCT04677803) | Medical University of Vienna | 2020-12-14 |
| SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Inhalation (NCT04631705) | University of Cologne | 2020-12-14 |
| A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis (NCT04631016) | AstraZeneca | 2020-12-14 |
| Ultramicronized Palmitoylethanolamide (PEA) Treatment in Hospitalized Participants With COVID-19 (NCT04619706) | Quantum Biopharma | 2020-12-14 |
| Study Evaluating the Safety and Efficacy of NCX 4251 Ophthalmic Suspension for the Treatment of Blepharitis (NCT04675242) | Nicox Ophthalmics, Inc. | 2020-12-14 |
| The CASCADE HF Soft Launch and Calibration Phase I and II (NCT04738279) | Endeavor Health | 2020-12-14 |
| EP0057 in Combination With Olaparib in Advanced Ovarian Cancer (NCT04669002) | Ellipses Pharma | 2020-12-14 |
| Using Romiplostim to Treat Low Platelet Counts During Chemotherapy in People With Lymphoma (NCT04673266) | Memorial Sloan Kettering Cancer Center | 2020-12-14 |
| GYNecological Cancers Treated with NETrin MAbs in Combination with Chemotherapy and /or Pembrolizumab (NCT04652076) | NETRIS Pharma | 2020-12-14 |
| A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001) (NCT04471727) | Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2020-12-14 |
| Thalidomide in the Treatment of Chronic Radiation Proctitis With Intractable Bleeding (NCT04680195) | Sixth Affiliated Hospital, Sun Yat-sen University | 2020-12-14 |
| A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline. (NCT04899271) | Dompé Farmaceutici S.p.A | 2020-12-14 |
| A Study to Assess Safety and Efficacy of PRL3-Zumab in Patients With Solid Tumors (NCT04452955) | Intra-IMMUSG Pte Ltd | 2020-12-12 |
| The Therapeutic Effect of Dau-Di-Wu-Gong in Patient With Ankle Fracture (NCT03805347) | Changhua Christian Hospital | 2020-12-12 |
| Osimertinib Combined With Anlotinib in EGFR T790M Mutated NSCLC Patients With Progression on Osimertinib Treatment (NCT04438902) | First Affiliated Hospital of Zhejiang University | 2020-12-12 |
| Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease (NCT04198922) | Fred Hutchinson Cancer Center | 2020-12-11 |
| [18F]Fluoroestradiol-PET/CT Imaging of Invasive Lobular Carcinoma (NCT04252859) | University of Utah | 2020-12-11 |
| LYT-100 in Post-acute COVID-19 Respiratory Disease (NCT04652518) | PureTech | 2020-12-11 |
| Convalescent Plasma for Treating Patients With COVID-19 Pneumonia Without Indication of Ventilatory Support (NCT04528368) | D'Or Institute for Research and Education | 2020-12-11 |
| A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older (NCT04652102) | CureVac | 2020-12-11 |
| Efficacy and Safety of hzVSF-v13 in Patients With COVID-19 Pneumonia (NCT04676971) | ImmuneMed, Inc. | 2020-12-11 |
| Evaluation of AMG 714 for Vitiligo (NCT04338581) | National Institute of Allergy and Infectious Diseases (NIAID) | 2020-12-11 |
| A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A Nephropathy (NCT04663204) | University of Leicester | 2020-12-10 |
| Local Anesthetic as Single Shot Versus Catheter in Patients Undergoing Video Assisted Thoracoscopic Surgery (NCT04559347) | Poovendran Saththasivam | 2020-12-10 |
| A Study of Romiplostim to Prevent Low Platelet Counts in Children and Young Adults Receiving Chemotherapy for Solid Tumors (NCT04671901) | Memorial Sloan Kettering Cancer Center | 2020-12-10 |
| Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia (NCT04662281) | Lexicon Pharmaceuticals | 2020-12-10 |
| The Safety and Efficacy Study of PROTOXIN in Subjects With Moderate to Severe Glabellar Lines (NCT04996810) | Protox Inc. | 2020-12-10 |
| Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease (NCT04588545) | H. Lee Moffitt Cancer Center and Research Institute | 2020-12-10 |
| A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteritis (NCT04633447) | Janssen Research & Development, LLC | 2020-12-10 |
| Dual-task Augmented Reality Treatment for Parkinson's Disease (NCT04634331) | The Cleveland Clinic | 2020-12-10 |
| Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema (NCT04697758) | AsclepiX Therapeutics, Inc. | 2020-12-10 |
| Adjuvant Apalutamide in Subjects With High-risk Localized or Locally Advanced Prostate Cancer After Radical Prostatectomy (NCT04295447) | Universität Münster | 2020-12-10 |
| Comparison of Clinical Efficiency of Photodynamic Therapy and Topical Corticosteroid in Treatment of Oral Lichen Planus (NCT04976673) | Wroclaw Medical University | 2020-12-10 |
| Using Cannabidiol to Treat Diabetic Peripheral Neuropathy of the Feet (NCT04679545) | Pure Green | 2020-12-10 |
| A Clinical Trial to Assess the Safety and Immunogenicity of Nanocovax in Heathy Volunteers (NCT04683484) | Nanogen Pharmaceutical Biotechnology Joint Stock Company | 2020-12-10 |
| Ivermectin in Adults With Severe COVID-19. (NCT04602507) | CES University | 2020-12-10 |
| Treating Anxiety in Parkinson's Disease With a Multi-Strain Probiotic (NCT03968133) | University of British Columbia | 2020-12-10 |
| Sintilimab Plus R-GemOx as Second-line Salvage Therapy in Patients With R/R DLBCL (NCT04659434) | Qian Wenbin | 2020-12-10 |
| Transplantation of Fibroblast for Correction of Nasolabial Folds (NCT03140319) | SCARM Institute, Tabriz, Iran | 2020-12-10 |
| Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19 (NCT04760821) | Ministry of Health, Brazil | 2020-12-10 |
| Neoadjuvant PD-1 Monoclonal Antibody Plus Cisplatin-based Chemotherapy in Locally Advanced Upper Tract Urothelial Carcinoma (NCT04672317) | RenJi Hospital | 2020-12-10 |
| Safety, Tolerability, and Efficacy Study of Valoctocogene Roxaparvovec in Hemophilia A With Active or Prior Inhibitors (NCT04684940) | BioMarin Pharmaceutical | 2020-12-10 |
| Assessing Safety, Hospitalization and Efficacy of rNAPc2 in COVID-19 (NCT04655586) | ARCA Biopharma, Inc. | 2020-12-10 |
| PRevention Using EPA Against coloREctal Cancer (NCT04216251) | Massachusetts General Hospital | 2020-12-09 |
| Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer (NCT04499053) | Georgetown University | 2020-12-09 |
| Effects of Tregalizumab on Allergen-induced Airway Responses and Airway Inflammation in Asthmatic Patients (NCT04673591) | T-Balance Therapeutics GmbH | 2020-12-09 |
| A Multiple-Dose Study of BLU-5937 in Chronic Pruritus Associated With Atopic Dermatitis (NCT04693195) | Bellus Health Inc. - a GSK company | 2020-12-09 |
| Bacteriophage Therapy in Patients With Urinary Tract Infections (NCT04287478) | Adaptive Phage Therapeutics, Inc. | 2020-12-09 |
| Efficacy and Safety of Paclitaxel (Albumin-bound) Combination With Carboplatin in Ovarian Cancer. (NCT04661696) | Chinese Academy of Medical Sciences | 2020-12-09 |
| Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 (NCT04563208) | University of Witwatersrand, South Africa | 2020-12-09 |