| Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer (NCT04493060) | Mayo Clinic | 2020-12-28 |
| Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable (NCT04730232) | Tianjin Medical University Second Hospital | 2020-12-27 |
| Perioperative Therapy for Hepatocellular Carcinoma (NCT04653389) | Zhejiang University | 2020-12-26 |
| Dexamethasone Solution and Dexamethasone in Mucolox™ (NCT04540133) | University of California, San Francisco | 2020-12-26 |
| Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma (NCT04417660) | National Cancer Institute (NCI) | 2020-12-26 |
| HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB) (NCT04684914) | Altimmune, Inc. | 2020-12-26 |
| TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine (NCT04671459) | Prof. Franciszek Lukaszczyk Memorial Oncology Center | 2020-12-26 |
| Neoadjuvant Nivolumab for Upper Tract Urothelial Carcinoma (NCT05160285) | YULISU | 2020-12-25 |
| Zanubrutinib Combined With Standard Chemotherapy in the Treatment for Patients With Diffuse Large B Cell Lymphoma (NCT04668365) | Henan Cancer Hospital | 2020-12-25 |
| Role of Alprazolam in the Management of Acute Coronary Syndrome (NCT04715269) | Sohaib Ashraf | 2020-12-25 |
| Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas (NCT04620187) | Dana-Farber Cancer Institute | 2020-12-24 |
| A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden (NCT04145115) | National Cancer Institute (NCI) | 2020-12-24 |
| Toripalimab Plus Bevacizumab and Chemotherapy as Neoadjuvant Therapy in Advanced MSI-H or dMMR Colorectal Cancer (NCT04988191) | Peking University | 2020-12-24 |
| Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study (NCT04690348) | Memorial Sloan Kettering Cancer Center | 2020-12-24 |
| Clinical Trial of CNCT19 Cell Injection in the Treatment of Relapsed or Refractory Acute Lymphoblastic Leukemia (NCT04684147) | Juventas Cell Therapy Ltd. | 2020-12-24 |
| Evaluating the Efficacy and Safety of ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects (NCT04228926) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2020-12-24 |
| Umbilical Cord Lining Stem Cells (ULSC) in Patients With COVID-19 ARDS (NCT04494386) | Restem, LLC. | 2020-12-23 |
| A Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer (NCT03989336) | Chinese PLA General Hospital | 2020-12-23 |
| RCT of Fomitopsis Officinalis and Trametes Versicolor to Treat COVID-19 (NCT04667247) | Gordon Saxe | 2020-12-23 |
| REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL) (NCT04523428) | Stichting Hemato-Oncologie voor Volwassenen Nederland | 2020-12-23 |
| MTX and Steroid for aGVHD Treatment (NCT04677868) | Peking University People's Hospital | 2020-12-23 |
| 'Re-Priming' RT After Incomplete Response to CAR-T in R/R NHL (NCT04601831) | University of Texas Southwestern Medical Center | 2020-12-23 |
| Efficacy and Safety of Calcifediol vs Placebo in Subjects With Vitamin D Deficiency (NCT04735926) | Faes Farma, S.A. | 2020-12-23 |
| "QUAD SHOT" Radiotherapy With Pembrolizumab in Patients With Recurrent Head & Neck Cancer (NCT04373642) | University of Oklahoma | 2020-12-23 |
| Efficacy and Safety of Pemafibrate for Nonalcoholic Fatty Liver Disease (NCT06623539) | Yokohama City University | 2020-12-23 |
| Study of Atezolizumab Combined With Split-dose Gemcitabine Plus Cisplatin in Urothelial Carcinoma (NCT04602078) | Spanish Oncology Genito-Urinary Group | 2020-12-23 |
| Colchicine for the Treatment of Cardiac Injury in Hospitalized Patients With COVID-19 (COLHEART-19) (NCT04762771) | Baptist Health South Florida | 2020-12-23 |
| UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC (NCT04940637) | University of Turin, Italy | 2020-12-23 |
| Nebulised Heparin to Reduce COVID-19 Induced Acute Lung Injury (NCT04511923) | University College Hospital Galway | 2020-12-23 |
| Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury (NCT04458324) | Spaulding Rehabilitation Hospital | 2020-12-22 |
| CT Evaluating the Efficacy of Pre-incisional Local Analgesia With Ropivacaine + Dexamethasone in Pain Management After Tonsillectomy (NCT05504967) | Clinical Academic Center (2CA-Braga) | 2020-12-22 |
| Neoadjuvant Immunotherapy With Tavo + Electroporation in Combination With Nivo. in Melanoma Patients (NCT04526730) | H. Lee Moffitt Cancer Center and Research Institute | 2020-12-22 |
| Treatment of Angiotensin Converting Enzyme Inhibitor-induced Angioedema (NCT04679311) | Washington University School of Medicine | 2020-12-22 |
| A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB) (NCT04441788) | Ionis Pharmaceuticals, Inc. | 2020-12-22 |
| Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma (NCT04205240) | Srinivas Devarakonda | 2020-12-22 |
| Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aeruginosa Lung Infections and Cystic Fibrosis (NCT04596319) | Armata Pharmaceuticals, Inc. | 2020-12-22 |
| AD109 Dose Finding in Mild to Moderate OSA (NCT04631107) | Apnimed | 2020-12-22 |
| MIS-C Comparative Effectiveness Study (NCT04898231) | University of California, San Diego | 2020-12-22 |
| Pemetrexed, Cisplatin With Soft Tissue Sarcoma (NCT04605770) | Yonsei University | 2020-12-22 |
| Predictive Biomarker for Efficacy and Safety of Combination of Chemotherapy and Tislelizumab in NSCLC (NCT05244837) | Hao Long | 2020-12-22 |
| Efficacy and Safety of MM-II for Treatment of Knee Pain in Subjects With Symptomatic Knee Osteoarthritis (NCT04506463) | Sun Pharmaceutical Industries Limited | 2020-12-22 |
| First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBV (NCT04778904) | Barinthus Biotherapeutics | 2020-12-22 |
| 'SOURCE - LUNG' Stereotactic Ablative Radiation Therapy Of UltRaCEntral LUNG Tumours (SOURCE Lung) (NCT04375904) | Cancer Trials Ireland | 2020-12-22 |
| Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathy (NCT04678895) | Dartmouth-Hitchcock Medical Center | 2020-12-22 |
| Zanubrutinib in Participants With Active Proliferative Lupus Nephritis (NCT04643470) | BeiGene | 2020-12-22 |
| Safety And Efficacy Of TKI Cessation For CML Patients With Stable Molecular Response In A Real World Population (NCT04626024) | Baylor College of Medicine | 2020-12-22 |
| An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors (NCT04305795) | Rakuten Medical, Inc. | 2020-12-21 |
| Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer (NCT04418219) | Thomas Jefferson University | 2020-12-21 |
| A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation (NCT04625270) | Verastem, Inc. | 2020-12-21 |
| Study To Assess Efficacy, Safety, Tolerability And Pharmacokinetics Of PF-07038124 Ointment In Participants With Atopic Dermatitis Or Plaque Psoriasis (NCT04664153) | Pfizer | 2020-12-21 |
| A Study Evaluating the Efficacy and Safety of CKD-314 in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia (NCT04628143) | Chong Kun Dang Pharmaceutical | 2020-12-21 |
| A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers (NCT04626635) | Regeneron Pharmaceuticals | 2020-12-21 |
| Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (NCT04300309) | Novartis Pharmaceuticals | 2020-12-21 |
| Efficacy and Safety of Tocotrienols in CADASIL (NCT04658823) | Hovid Berhad | 2020-12-21 |
| Ablation Plus Tislelizumab Versus Ablation Alone for Intrahepatic Recurrent Early Stage HCC (NCT04663035) | Ming Zhao | 2020-12-21 |
| Efficacy and Safety of Standard of Care Plus Durvalumab in Patients With Limited Disease Small Cell Lung Cancer (DOLPHIN) (NCT04602533) | Michael Hopp | 2020-12-21 |
| InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O ) (NCT04426201) | Revimmune | 2020-12-20 |
| Mecapegfilgrastim(PEG-G-CSF) for Prophylaxis of Chemotherapy-induced Neutropenia in Patients With Lymphoma (NCT04460508) | The First Hospital of Jilin University | 2020-12-20 |
| Comparison of Duloxetine Versus Pregabalin (NCT04727502) | National Cancer Institute, Egypt | 2020-12-20 |
| Oral Camostat Compared With Standard Supportive Care in Mild-Moderate COVID-19 Patients (NCT04524663) | Stanford University | 2020-12-19 |
| A Dose-ranging Pediatric Study of an Adjuvanted Pandemic Influenza Vaccine (NCT04669691) | Seqirus | 2020-12-19 |
| Combination of Nimotuzumab and Radiotherapy for Recurrent Uterine Cervical Squamous Carcinoma (NCT04664244) | Lei Li | 2020-12-19 |
| Tamoxifen Therapy for Myotubular Myopathy (NCT04915846) | James Dowling | 2020-12-18 |
| A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) (NCT04702568) | BioCryst Pharmaceuticals | 2020-12-18 |
| A Phase Ⅱ Trial of Neoadjuvant Toripalimab Plus Platinum-doublet Chemotherapy in Locally Advanced NSCLC. (NCT04606303) | Peking University Cancer Hospital & Institute | 2020-12-18 |
| Nivolumab Plus Axitinib in Patients With Anti-PD1 Refractory Advanced Melanoma (NCT04493203) | Yana Najjar | 2020-12-18 |
| Mouth Rinses for Inactivation of COVID-19 (NCT04584684) | University of North Carolina, Chapel Hill | 2020-12-18 |
| CHF6563 in Babies With Neonatal Opioid Withdrawal Syndrome (NCT04104646) | Chiesi Farmaceutici S.p.A. | 2020-12-18 |
| Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients (NCT04721873) | University of California, San Diego | 2020-12-18 |
| Neurocircuit Strategy to Decrease Cocaine Cue Reactivity (NCT04155632) | Medical University of South Carolina | 2020-12-18 |
| A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy (NCT04640623) | Janssen Research & Development, LLC | 2020-12-18 |
| Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial) (NCT04692740) | Michele Reni | 2020-12-18 |
| Niraparib + Dostarlimab In BRCA Mutated Breast Cancer (NCT04584255) | Dana-Farber Cancer Institute | 2020-12-18 |
| Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations (NCT04641442) | Novartis Pharmaceuticals | 2020-12-18 |
| A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC) (NCT04663308) | Mirum Pharmaceuticals, Inc. | 2020-12-18 |
| Pharmacokinetics and Pharmacodynamics of Tranexamic Acid in Women Having Caesarean Section Birth [WOMAN-PharmacoTXA] (NCT04274335) | London School of Hygiene and Tropical Medicine | 2020-12-18 |
| A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy (NCT04666740) | Memorial Sloan Kettering Cancer Center | 2020-12-18 |
| SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI) (NCT04344184) | Virginia Commonwealth University | 2020-12-18 |
| HEALEY ALS Platform Trial - Regimen D Pridopidine (NCT04615923) | Merit E. Cudkowicz, MD | 2020-12-18 |
| Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis (NCT04384692) | Fred Hutchinson Cancer Center | 2020-12-18 |
| Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03) (NCT04626518) | Merck Sharp & Dohme LLC | 2020-12-17 |
| Ketamine for the Treatment of Opioid Use Disorder and Depression (NCT04177706) | Medical University of South Carolina | 2020-12-17 |
| SHR7390 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer (NCT04676607) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2020-12-17 |
| A Trial of HR021618 in Postsurgical Pain Management (NCT04699175) | Jiangsu HengRui Medicine Co., Ltd. | 2020-12-17 |
| A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL) (NCT04546399) | National Cancer Institute (NCI) | 2020-12-17 |
| A Phase II/III Study of Sargramostim (NCT04642950) | Nobelpharma | 2020-12-17 |
| Vactosertib in Combination with Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects (NCT04515979) | MedPacto, Inc. | 2020-12-17 |
| A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide (NCT04669665) | Seelos Therapeutics, Inc. | 2020-12-17 |
| Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension (NCT04742283) | Santen Inc. | 2020-12-17 |
| Tricaprilin Phase 2 Pilot Study in Migraine (NCT04437199) | Cerecin | 2020-12-17 |
| ALL SCTped 2012 FORUM Add-on Study Blina Post HSCT (NCT04785547) | Prof. Christina Peters | 2020-12-17 |
| COMPARATIVE ANALYSIS OF INNOVATIVE BONE HEALING TECHNIQUES (NCT05480631) | Dow University of Health Sciences | 2020-12-17 |
| Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency (NCT04098237) | Andrew Hendifar, MD | 2020-12-17 |
| Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal (NCT04218240) | University of Pennsylvania | 2020-12-17 |
| Efficacy and Safety of hzVSF-v13 in Moderate to Severe Patients With COVID-19 Pneumonia (NCT04679415) | ImmuneMed, Inc. | 2020-12-17 |
| A Study to Assess the Efficacy and Safety of Vatiquinone for the Treatment of Participants With Friedreich Ataxia (NCT04577352) | PTC Therapeutics | 2020-12-17 |
| Fluzoparib in Patients With Metastatic Non-clear Cell Renal Cell Carcinoma (NCT04535687) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2020-12-17 |
| Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis (NCT04430179) | University of South Florida | 2020-12-17 |
| Efficacy of Olanzapine, Netupitant and Palonosetron in Controlling Nausea and Vomiting Associated With Highly Emetogenic Chemotherapy in Patients With Breast Cancer (NCT04669132) | Instituto Brasileiro de Controle do Cancer | 2020-12-17 |
| Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung Cancer (NCT04622228) | Hoffmann-La Roche | 2020-12-16 |