| Hippocampal Response to Acute Oral Doses of CBD During an fMRI Memory Task (NCT04778644) | Hartford Hospital | 2021-12-15 |
| Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste) (NCT05176717) | Laboratoires Thea | 2021-12-15 |
| The DESyne BDS Plus RCT: A Randomized Clinical Trial to Assess the Elixir DESyne BDS Plus Drug Eluting Coronary Stent System for the Treatment of de Novo Native Coronary Artery Lesions (NCT05033964) | Elixir Medical Corporation | 2021-12-15 |
| Montelukast Use in Rheumatoid Arthritis (NCT05447520) | Noha Mansour | 2021-12-15 |
| Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy (NCT05167721) | Mayo Clinic | 2021-12-15 |
| Study of Magrolimab Combination Therapy in Patients With Non-Surgically Removable Locally Advanced or Metastatic Triple-Negative Breast Cancer (NCT04958785) | Gilead Sciences | 2021-12-14 |
| Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM (NCT04791969) | Glenn-Milo Santos | 2021-12-14 |
| A Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse." (NCT04998786) | Nantes University Hospital | 2021-12-14 |
| Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor (NCT05198310) | Kiniksa Pharmaceuticals, Ltd. | 2021-12-14 |
| Tadalafil as Adjuvant Therapy for DMD (NCT05195775) | University of Florida | 2021-12-14 |
| Hypofractionated Radiation Therapy for Merkel Cell Carcinoma (NCT05100095) | M.D. Anderson Cancer Center | 2021-12-14 |
| Ticagrelor Monotherapy After Stenting (NCT05149560) | Vastra Gotaland Region | 2021-12-14 |
| Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer (NCT04731844) | University of Rochester | 2021-12-14 |
| Contrast-Enhanced Ultrasound for the Prediction of Bile Duct Cancer Response to Radioembolization Treatment (NCT05328167) | Thomas Jefferson University | 2021-12-14 |
| Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma (NCT04019262) | John Flickinger | 2021-12-14 |
| Cabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1 Inhibitors (NCT04767906) | University of Leipzig | 2021-12-14 |
| Mobile App for Smoking Cessation and Mental Health (NCT04887558) | University of Oklahoma | 2021-12-14 |
| Tranexamic Acid Dosing for Major Joint Replacement Surgery (NCT05075200) | Sunnybrook Health Sciences Centre | 2021-12-14 |
| Safety, Tolerability, and Treatment Effect of Belnacasan in Patients With COVID-19 (NCT05164120) | MedStar Health | 2021-12-14 |
| to Assess the Accuracy and Reliability of the Ga68-Dolacga Positron Emission Tomography Compared to Computer Tomography Volumetry and Indocyanine Green Retention Test for Measurement of Liver Reserve (NCT05007548) | National Atomic Research Institute, Taiwan | 2021-12-14 |
| Evaluation of the Hemocompatibility of the Direct Oral Anti-Coagulant Apixaban in Left Ventricular Assist Devices (NCT04865978) | Palak Shah | 2021-12-14 |
| Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 Parosmia (NCT05216614) | Washington University School of Medicine | 2021-12-14 |
| Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial Malignancies (NCT04648826) | National Cancer Institute (NCI) | 2021-12-14 |
| Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure) (NCT04954859) | GlaxoSmithKline | 2021-12-14 |
| Neoadjuvant HS-10296 (Almonertinib) Therapy for Potential Resectable Stage III EGFR Mutation-Positive Non-small Cell Lung Cancer (NCT04685070) | Shanghai Pulmonary Hospital, Shanghai, China | 2021-12-14 |
| The Efficacy And Safety Of Mitizodone Phosphate Tablets In The Treatment of Patient With Major Depressive Disorder (NCT04984512) | Sunshine Lake Pharma Co., Ltd. | 2021-12-14 |
| Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer (NCT04847466) | National Cancer Institute (NCI) | 2021-12-14 |
| Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens (NCT04821141) | University of Kansas Medical Center | 2021-12-14 |
| Fixed-duration Therapy With Ibrutinib and Obinutuzumab (GA-101) in Treatment-naïve Patients With CLL (NCT04908228) | Paolo Ghia | 2021-12-13 |
| Oral Minoxidil for the Treatment of Recurrent Platinum Resistant Epithelial Ovarian Cancer (NCT05272462) | Loyola University | 2021-12-13 |
| Efficacy and Safety of LEO 152020 Tablets for the Treatment of Adults With Moderate to Severe Atopic Dermatitis (NCT05117060) | JW Pharmaceutical | 2021-12-13 |
| A Study of KN046 in Patients With Thymic Carcinoma Who Failed Immune Checkpoint Inhibitors (NCT04925947) | Weill Medical College of Cornell University | 2021-12-13 |
| SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma. (NCT05022654) | Sichuan Baili Pharmaceutical Co., Ltd. | 2021-12-13 |
| Study to Assess the Safety, Tolerability, and Effects of CHI-202 to Support Recovery From Physical Activity (NCT05026164) | Canopy Growth Corporation | 2021-12-13 |
| Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS (NCT04741945) | Kirsten Grønbæk | 2021-12-13 |
| Safety and Efficacy of 50 mg NYX-783 QD vs. Placebo in PTSD (NCT05181995) | Aptinyx | 2021-12-13 |
| Human Laboratory Study of ASP8062 for Alcohol Use Disorder (NCT05096117) | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 2021-12-13 |
| Tangningtongluo Tablet for People With Prediabetes (NCT05126251) | Beijing University of Chinese Medicine | 2021-12-13 |
| Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca (NCT04988074) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2021-12-13 |
| Caring Relationships Expression Study (NCT05627687) | Arizona State University | 2021-12-13 |
| ALTO-300 in Depression (NCT05118750) | Alto Neuroscience | 2021-12-13 |
| Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy (NCT05020912) | Case Comprehensive Cancer Center | 2021-12-13 |
| GEN1047 for Solid Tumors - First in Human (FIH) Trial (NCT05180474) | Genmab | 2021-12-13 |
| Study Testing Response Effect of KY1005 Against Moderate-to-Severe Atopic Dermatitis, The STREAM-AD Study (NCT05131477) | Kymab Limited | 2021-12-13 |
| Drug-drug Interaction Study of SPH3127 (NCT05359055) | Shanghai Pharmaceuticals Holding Co., Ltd | 2021-12-13 |
| A Phase II Safety and Tolerability Study of TCB008 in Patients With COVID-19 (NCT04834128) | TC Biopharm | 2021-12-13 |
| A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP) (NCT04993768) | Transposon Therapeutics, Inc. | 2021-12-12 |
| Efficacy and Safety of Belimumab in Neuromyelitis Optica Spectrum Disorders (NCT05154734) | Tianjin Medical University General Hospital | 2021-12-12 |
| Palbociclib Combine With Anti-HER2 Therapy in Triple Positive ABC (NCT05969184) | Peking University Cancer Hospital & Institute | 2021-12-12 |
| Tislelizumab（Anti PD-1), Lenvatinib and GEMOX Transformation in the Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer (NCT05156788) | Shanghai Zhongshan Hospital | 2021-12-12 |
| Comparison of Different Volumes Spread of Erector Spinae Block in Post Mastectomy Pain Syndrome Management (NCT05192278) | Mansoura University | 2021-12-12 |
| Proof of Concept Study of Rilzabrutinib in Adult Participants With Moderate-to-severe Asthma (NCT05104892) | Sanofi | 2021-12-12 |
| Dengue Controlled Human Infection Model in Dhaka, Bangladesh (NCT05229354) | Beth Kirkpatrick | 2021-12-11 |
| Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Moderate to Severe Acne Vulgaris With Photodynamic Therapy in Adults (NCT05080764) | Biofrontera Inc. | 2021-12-10 |
| The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs (NCT05159245) | Helsinki University Central Hospital | 2021-12-10 |
| A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children Aged 2-17 Years With CAH (NCT05128942) | Spruce Biosciences | 2021-12-10 |
| Perioperative Leucovorin, Oxaliplatin, Docetaxel and S-1 (LOTS) For Locally Advanced Gastric or Gastroesophageal Junction Cancer (NCT04999332) | National Cheng-Kung University Hospital | 2021-12-10 |
| Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Untreated Salivary Gland Malignant Neoplasms (NCT05000892) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2021-12-10 |
| ADMIRAL Trial: Adaptive Mediastinal Radiation With Chemo-Immunotherapy (NCT04372927) | University of Washington | 2021-12-10 |
| Platelet Rich Fibrin Versus Melatonin Around Dental Implants (NCT05593731) | Misr University for Science and Technology | 2021-12-10 |
| The Efficacy and Safety of HLX208 in Advanced Anaplastic Thyroid Cancer (ATC) With BRAF V600 Mutation (NCT05102292) | Shanghai Henlius Biotech | 2021-12-10 |
| Safety, Pharmacokinetics and Clinical Activity of AZD0171 in Combination With Durvalumab and Chemotherapy in Locally Advanced or Metastatic Solid Tumours (NCT04999969) | AstraZeneca | 2021-12-10 |
| Optimization of Immunotherapy Treatment for Advanced Melanoma in the Context of the Public Brazilian Health System (OTIMAS) (NCT07376317) | Instituto do Cancer do Estado de São Paulo | 2021-12-10 |
| A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) (NCT04907851) | Redx Pharma Ltd | 2021-12-10 |
| Neuromodulatory Effects of Transcranial Pulsed Current Stimulation in Fibromyalgia (NCT05321693) | Centro Universitario La Salle | 2021-12-10 |
| Safety and Efficacy of Topical Moxifloxacin for Prevention of Post-Traumatic Endophthalmitis: Randomized Controlled Clinical Trial (NCT05162625) | University of Campinas, Brazil | 2021-12-10 |
| Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low Viremia (NCT05203055) | Fuzhou General Hospital | 2021-12-10 |
| To Evaluate the Safety and Primary Immunogenicity of Cell-free (Three-component) Combination Vaccine for Phase I Immunogenicity in Children and Infants (NCT05189548) | Changchun BCHT Biotechnology Co. | 2021-12-10 |
| Atezolizumab in Patients With MSI-h/MMR-D Stage II High Risk and Stage III Colorectal Cancer Ineligible for Oxaliplatin (NCT05118724) | AIO-Studien-gGmbH | 2021-12-10 |
| NTLA-2002 in Adults With Hereditary Angioedema (HAE) (NCT05120830) | Intellia Therapeutics | 2021-12-10 |
| Surufatinib in Patients With Osteosarcoma and Soft Tissue Sarcoma (NCT05106777) | Sun Yat-sen University | 2021-12-10 |
| Namodenoson in the Treatment of Non-Alcoholic Steatohepatitis (NASH) (NCT04697810) | Can-Fite BioPharma | 2021-12-10 |
| Bladder Cancer and ExeRcise Training During IntraVesical ThErapy (NCT04593862) | University of Alberta | 2021-12-09 |
| Concomitant Radiotherapy, Tremelimumab & Durvalumab for Advanced NSCLC Patients Progressing on First-line Immunotherapy (NCT05000710) | Sheba Medical Center | 2021-12-09 |
| Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies (NCT05013099) | ImaginAb, Inc. | 2021-12-09 |
| Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma (NCT04977375) | Chirag G. Patil | 2021-12-09 |
| Letrozole and Misoprostol for Termination of Pregnancy up to 63 Days' Gestation (NCT05207644) | Gynuity Health Projects | 2021-12-09 |
| Efficacy and Safety of Furmonertinib in EGFR-Mutant, PD-L1+ Patients With Locally Advanced or Metastatic NSCLC (FUTURE) (NCT05255406) | Fudan University | 2021-12-09 |
| A Study Evaluating the Safety and Efficacy of Tirofiban in Combination With Alteplase in Acute Ischemic Stroke (NCT05188417) | GrandPharma (China) Co., Ltd. | 2021-12-09 |
| 4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration (NCT05197270) | 4D Molecular Therapeutics | 2021-12-09 |
| Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/Refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide in MSS Metastatic Colorectal Carcinoma (mCRC) (NCT05061017) | Diwakar Davar | 2021-12-09 |
| A Study of Stereotactic Body Radiation Therapy (SBRT) Without Androgen Deprivation Therapy (ADT) in People With Unfavorable Intermediate-Risk Prostate Cancer (NCT05169970) | Memorial Sloan Kettering Cancer Center | 2021-12-09 |
| A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203) (NCT05104567) | Sanofi | 2021-12-09 |
| A Study on the Safety and Effectiveness of Tislelizumab Combined With Axitinib for Neoadjuvant Treatment of ccRCC (NCT05172440) | Hongqian Guo | 2021-12-09 |
| MITO 35a: Olaparib Maintenance Therapy in Newly Diagnosed BRCA Wild-type Advanced Ovarian, Fallopian Tube and Primitive Peritoneal Cancer (NCT05233982) | National Cancer Institute, Naples | 2021-12-09 |
| RESET-medication Glucocorticoid Receptor (GR) Blockade As Disease Modifying Treatment for Depression with Childhood Trauma (NCT05217758) | Amsterdam UMC, location VUmc | 2021-12-09 |
| A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's Disease (NCT05111249) | Novartis Pharmaceuticals | 2021-12-08 |
| A Trial of Palliative Chemotherapy, Radiation and Immune Treatment for Oesophageal Cancer: PALEO Study (NCT06290505) | Australasian Gastro-Intestinal Trials Group | 2021-12-08 |
| Mycophenolate in Limited Cutaneous Systemic Sclerosis (MINIMISE-Pilot) (NCT04927390) | University College, London | 2021-12-08 |
| Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes (NCT06286878) | University of Sao Paulo | 2021-12-08 |
| Early Infant Micronutrition and Development (NCT05005897) | Sykehuset Innlandet HF | 2021-12-08 |
| A Study of Isatuximab Added to Standard CyBorD Induction and Lenalidomide Maintenance Treatments in ND-TEMM (NCT04786028) | Canadian Myeloma Research Group | 2021-12-08 |
| Famitinib Plus SHR6390 and Endocrine Therapy in the Treatment of HR-positive, HER2-negative Advanced Breast Cancer (NCT05176080) | Henan Cancer Hospital | 2021-12-08 |
| Phase II Clinical Study of Pyrotinib in First-line Treatment of Primary HER2-amplified/Mutated Advanced Non-small Cell Lung Cancer (NCT05751018) | Peking Union Medical College Hospital | 2021-12-08 |
| A Phase II Study of Fruquintinib Combined With Capecitabine as First-line Treatment for Advanced Metastatic Colorectal Cancer Unsuitable for Intravenous Chemotherapy (NCT04866108) | Beijing Friendship Hospital | 2021-12-08 |
| A Study to Assess the Effects of Nemolizumab on Cytochrome P450 Substrates in Participants With Moderate-to-Severe Atopic Dermatitis (NCT04562116) | Galderma R&D | 2021-12-08 |
| A Study to Assess YH003 in Combination with Toripalimab(anti-PD-1 MAb) Injection in Patients with Cancers (NCT05031494) | Eucure (Beijing) Biopharma Co., Ltd | 2021-12-08 |
| Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma (NCT04817254) | National Cancer Institute (NCI) | 2021-12-08 |
| First-in-human Study of SAR443579 Infusion in Male and Female Children and Adult Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) (NCT05086315) | Sanofi | 2021-12-08 |
| Trilaciclib in Patients Receiving Sacituzumab Govitecan-hziy for Triple Negative Breast Cancer (NCT05113966) | G1 Therapeutics, Inc. | 2021-12-08 |