| Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius) (NCT05158296) | Laboratoires Thea | 2021-12-08 |
| Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma (NCT04919642) | TransThera Sciences (Nanjing), Inc. | 2021-12-07 |
| Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (NCT05124678) | Makerere University | 2021-12-07 |
| SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC. (NCT05020457) | Sichuan Baili Pharmaceutical Co., Ltd. | 2021-12-07 |
| LYT-300 in Healthy Volunteers (NCT05129865) | PureTech | 2021-12-07 |
| Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types (NCT05000294) | University of Florida | 2021-12-07 |
| A Study of SAR444245 With or Without Other Anticancer Therapies for the Treatment of Adults and Adolescents With Relapsed or Refractory B Cell Lymphoma (Master Protocol) [Pegathor Lymphoma 205] (NCT05179603) | Sanofi | 2021-12-07 |
| The Study of Olaparib in Newly Diagnosed mCRPC Patients With HRR Gene Mutation (NCT05262608) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2021-12-07 |
| ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN (NCT04639024) | Gwynn Long, M.D. | 2021-12-07 |
| Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (NCT04997902) | Kura Oncology, Inc. | 2021-12-07 |
| Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia (NCT05182476) | Neurocrine Biosciences | 2021-12-07 |
| [18F]FPIA PET/CT Imaging in Patients With Solid Tumours (NCT04717674) | University College, London | 2021-12-07 |
| Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA) (NCT05002777) | Sanofi | 2021-12-07 |
| A Study of CIN-107 in Patients With Uncontrolled Hypertension (NCT05137002) | CinCor Pharma, Inc. | 2021-12-07 |
| NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies (NCT05023486) | Novita Pharmaceuticals, Inc. | 2021-12-07 |
| A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome (NCT05211830) | Sixera Pharma | 2021-12-07 |
| Oral Lactobacillus Rhamnosus TCELL-1 and Colorectal Cancer (NCT05570942) | National Taiwan University Hospital | 2021-12-07 |
| Chlorpheniramine Nasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: ACCROS-I (NCT05449405) | Dr. Ferrer BioPharma | 2021-12-07 |
| Depleted Donor Stem Cell Transplant in Children and Adults With Fanconi Anemia After Being Conditioned With a Regimen Containing Briquilimab (NCT04784052) | Porteus, Matthew, MD | 2021-12-07 |
| Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant (NCT05027425) | University of Cincinnati | 2021-12-07 |
| Pembrolizumab Monotherapy Following Tri-modality Treatment for Selected Patients With Muscle-invasive Bladder Cancer (NCT05072600) | Peking University First Hospital | 2021-12-07 |
| Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site (NCT05110781) | University of California, Davis | 2021-12-07 |
| A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder (NCT05103657) | Boehringer Ingelheim | 2021-12-07 |
| Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrophic Scars (NCT05196373) | Sirnaomics | 2021-12-07 |
| Frailty Score-guided Dosing of Lenalidomide, Dexamethasone and Daratumumab Induction Therapy (NCT04223661) | Attaya Suvannasankha | 2021-12-06 |
| BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy (NCT05116774) | BioCryst Pharmaceuticals | 2021-12-06 |
| The Efficacy and Safety of HLX208 in Adult Langerhans Cell Histiocytosis (LCH) and Erdheim-Chester Disease (ECD) With BRAF V600E Mutation (NCT05092815) | Shanghai Henlius Biotech | 2021-12-06 |
| COVID Protection After Transplant-Immunosuppression Reduction (NCT05077254) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-12-06 |
| Short-term Pre-OPerative Durvalumab (MEDI 4736) in Early Small Triple Negative Breast Cancer Patients (POP-Durva) (NCT05215106) | Gustave Roussy, Cancer Campus, Grand Paris | 2021-12-06 |
| Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer (NCT04821284) | Flemming Forsberg | 2021-12-06 |
| Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA (NCT05079035) | BioTissue Holdings, Inc | 2021-12-06 |
| A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET) (NCT05122650) | Jazz Pharmaceuticals | 2021-12-06 |
| Extension Study of Infigratinib in Children With Achondroplasia (ACH) (NCT05145010) | QED Therapeutics, a BridgeBio company | 2021-12-06 |
| Outpatient Liquid Aspirin (OLA) (NCT04937088) | Louisiana State University Health Sciences Center in New Orleans | 2021-12-06 |
| A Safety and Tolerability Study of NC318 in Combination With Chemotherapy for Subjects With Advanced or Metastatic NSCLC (NCT04430933) | NextCure, Inc. | 2021-12-06 |
| Study of Efficacy and Safety of CML-CP Patients Treated With Asciminib Versus Best Available Therapy, Previously Treated With 2 or More Tyrosine Kinase Inhibitors (NCT04795427) | Novartis Pharmaceuticals | 2021-12-06 |
| A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Vaccine Boosters (NCT05137236) | ModernaTX, Inc. | 2021-12-06 |
| The Effect of Minocycline and N-acetylcysteine for the Treatment of Fibromyalgia (NCT04594733) | Medical University of South Carolina | 2021-12-06 |
| Phase 1/2 Dose Confirmation Study of FLT180a in Hemophilia B (NCT05164471) | Spur Therapeutics | 2021-12-06 |
| 68Ga-DOTATATE Neuroblastoma Imaging Pilot (NCT04559217) | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | 2021-12-06 |
| EFFECTIVENESS of PROBIOTICS in ADULTS with MODERATE to SEVERE PERSISTENT ASTHMA (NCT06657066) | King Edward Medical University | 2021-12-06 |
| Letermovir for CMV Prevention After Lung Transplantation (NCT05041426) | Fernanda P Silveira, MD, MS | 2021-12-06 |
| A Study of XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors (NCT04996121) | Xuanzhu Biopharmaceutical Co., Ltd. | 2021-12-06 |
| KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer (NCT05027867) | Kartos Therapeutics, Inc. | 2021-12-06 |
| Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma (NCT04852328) | Washington University School of Medicine | 2021-12-06 |
| Donafenib Plus Sintilimab for Advanced HCC (NCT05162352) | Second Affiliated Hospital of Guangzhou Medical University | 2021-12-04 |
| Long-term Safety and Efficacy Profile of ABX464 in Subjects With Moderate to Severe Active Ulcerative Colitis (NCT05177835) | Abivax S.A. | 2021-12-03 |
| Trial in AML Secondary to MPNs Patients, Unfit for Intensive Chemotherapy, Investigating a Treatment Combination Including Decitabine and Venetoclax (NCT04763928) | Gruppo Italiano Malattie EMatologiche dell'Adulto | 2021-12-03 |
| Envafolimab Combined With Chemotherapy and Recombinant Human Endostatin in the First-line Treatment of Sq-NSCLC (NCT05243355) | Qilu Hospital of Shandong University | 2021-12-03 |
| A Phase I/II Clinical Trial in Healthy People Aged 18 Years and Above (NCT05144139) | Stemirna Therapeutics | 2021-12-03 |
| Anti-NKG2A Monoclonal Antibody for AML or MDS Patients Undergoing Haploidentical Transplantation (NCT06892223) | Istituto Clinico Humanitas | 2021-12-03 |
| Efficacy and Biomarker Explanation of IBI-322 Plus Lenvatinib on Extensive Stage Small Cell Lung Cancer (NCT05296603) | Hunan Province Tumor Hospital | 2021-12-03 |
| Contrast Enhanced Ultrasound for Renal Obstruction (NCT05090800) | University of Michigan | 2021-12-03 |
| Belantamab Mafodotin, Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma (NCT04896658) | University of Maryland, Baltimore | 2021-12-03 |
| A Study to Evaluate the Safety and Tolerability of AZD7442 in Chinese Adults (NCT05184062) | AstraZeneca | 2021-12-03 |
| Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcohol Use Disorder (NCT05093296) | Central Institute of Mental Health, Mannheim | 2021-12-02 |
| A Study to Test Whether BI 706321 Combined With Ustekinumab Helps People With Crohn's Disease (NCT04978493) | Boehringer Ingelheim | 2021-12-02 |
| Phase 1/2 Study of TU2218 Alone and in Combination With Checkpoint Inhibitors in Patients With Advanced Solid Tumors (NCT05204862) | TiumBio Co., Ltd. | 2021-12-02 |
| Trial of High-Dose Vitamin D in the Treatment of Complicated Severe Acute Malnutrition (NCT04270643) | Queen Mary University of London | 2021-12-02 |
| A Proof-of-concept Trial to Evaluate the Safety and Efficacy of UB-421 Plus Chidamide in Changing HIV Reservoirs (NCT05056974) | United BioPharma | 2021-12-02 |
| Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GMCSF) and Isotretinoin for Consolidation of Patients With High-Risk Neuroblastoma in First Remission. (NCT04909515) | Y-mAbs Therapeutics | 2021-12-02 |
| Efficacy of Erenumab in Chronic Cluster Headache (NCT04970355) | Charite University, Berlin, Germany | 2021-12-02 |
| Treatment Interrupts Depression Early (NCT05002309) | Nova Scotia Health Authority | 2021-12-02 |
| A Study of Amivantamab in People With Esophagogastric Cancer (NCT05117931) | Memorial Sloan Kettering Cancer Center | 2021-12-02 |
| Extension Study to PTR-01-002 (A Study in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Patients Previously Treated With PTR-01) (NCT05143190) | Phoenix Tissue Repair, Inc. | 2021-12-02 |
| Study of Trans Sodium Crocetinate in Patients With Interstitial Lung Disease (NCT05079126) | Diffusion Pharmaceuticals Inc | 2021-12-02 |
| A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH) (NCT05036135) | Aerovate Therapeutics | 2021-12-02 |
| Salvage Immunotherapy and Chemotherapy in Esophageal Squamous Cell Carcinoma Patients Nonresponding to Initial Neoadjuvant Chemoradiotherapy (NCT05103501) | Shanghai Chest Hospital | 2021-12-01 |
| Exploratory Study on Dosage of Qizhi Weitong Granules in the Treatment of Irritable Bowel Syndrome （IBS) (NCT05113888) | China Resources Sanjiu Medical & Pharmaceutical Co., Ltd. | 2021-12-01 |
| Riboflavin for Glutamate Reduction in Alcohol Withdrawal (NCT04232800) | Oregon Health and Science University | 2021-12-01 |
| Induction Chemotherapy Sequential Sintilimab Combined With Dual Epigenetic Drugs for ENKTL-HLH (NCT05008666) | Sun Yat-sen University | 2021-12-01 |
| Selective Estrogen Modulation and Melatonin in Early COVID-19 (NCT04531748) | Reena Mehra, MD | 2021-12-01 |
| Decitabine and HQP1351-based Chemotherapy Regimen for the Treatment Advanced CML (NCT05376852) | Nanfang Hospital, Southern Medical University | 2021-12-01 |
| IIT Assessing OC-01Nasal Spray on Symptoms of DED Following CXL (NCT05136924) | Vance Thompson Vision - MT | 2021-12-01 |
| Donafenib Combined With TACE as Adjuvant Therapy of Patients With Hepatocellular Carcinoma (NCT05161143) | Peking Union Medical College Hospital | 2021-12-01 |
| Anlotinib Plus Everolimus as First-line Treatment for Advanced Non Clear Cell Renal Cell Carcinoma (NCT05124431) | Fudan University | 2021-12-01 |
| Consolidative Radiotherapy Combined With Camrelizumab and Chemotherapy for Oligometastatic Nasopharyngeal Carcinoma (NCT05128201) | Jiangxi Provincial Cancer Hospital | 2021-12-01 |
| Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer (NCT05136326) | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 2021-12-01 |
| Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging (NCT04120766) | Gregory Jicha, MD, PhD | 2021-12-01 |
| the Effect of Preoperative Sodium Ibuprofen on Postoperative Endodontic Pain (NCT04964622) | Cairo University | 2021-12-01 |
| AZA Combined With NAC for PIT After HSCT (NCT05126004) | The First Affiliated Hospital of Soochow University | 2021-12-01 |
| Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma (NCT04910022) | Nerviano Medical Sciences | 2021-12-01 |
| An Extension Study of Belcesiran in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATLD) (NCT05146882) | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | 2021-12-01 |
| MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients (NCT04646603) | MedRegen LLC | 2021-12-01 |
| A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal Mesothelioma (NCT05041062) | University of Chicago | 2021-12-01 |
| Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern (NCT05168813) | COVID-19 Prevention Network | 2021-12-01 |
| Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema (NCT04898309) | AO GENERIUM | 2021-12-01 |
| Safety and Feasibility of Argatroban As Anticoagulant in Adults with ECMO (NCT05226442) | Medical University of Vienna | 2021-12-01 |
| Safety & Efficacy of AlloRx SC® in PTHS Patients (NCT05165017) | Vitro Biopharma Inc. | 2021-12-01 |
| A Study to Assess the Effectiveness and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP). (NCT05039515) | Clementia Pharmaceuticals Inc. | 2021-12-01 |
| Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM) (NCT05130047) | Michael Camilleri, MD | 2021-12-01 |
| A Clinical Trial to Evaluate TQB2858 Injection Combined With Anlotinib Hydrochloride Capsule in the Treatment of Recurrent or Metastatic Advanced Endometrial Carcinoma (NCT05121363) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-12-01 |
| Local Betamethasone Versus Triamcinolone Injection in Management of Thyroid Eye Disease (NCT04976816) | Assiut University | 2021-12-01 |
| Effects of Low Protein Diet Supplemented With Ketoanalogues on Preservation of Kidney Function in Incremental Dialysis (NCT05030168) | Chulalongkorn University | 2021-12-01 |
| Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy (NCT05169554) | Fundacion Agencia Aragonesa para la Investigacion y Desarrollo (ARAID) | 2021-12-01 |
| The Safety, Tolerability and Immunogenicity of COVID-19 Vaccine (SCTV01C) in Healthy, Unvaccinated Adults (NCT05148091) | Sinocelltech Ltd. | 2021-12-01 |
| Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms. (NCT05096468) | Beijing Tiantan Hospital | 2021-12-01 |
| Ensatinib Treat Second-generation ALK-TKI Resistance After Second-generation ALK-TKI Resistance (NCT05178511) | Li Zhang, MD | 2021-12-01 |
| Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient With Both Multidrug-resistant TB and COVID-19 (NCT05077813) | Kafrelsheikh University | 2021-12-01 |
| Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism (NCT03446807) | Loma Linda University | 2021-12-01 |