| Blinatumomab Combined With Low-dose DLI as Maintenance Therapy After Transplantation for B-ALL (NCT07677878) | Liping Dou | 2024-12-01 |
| BIOmarker-guided Study to Evaluate the Efficacy and Safety of cemipLimab for advancEd Cutaneous T-cell Lymphoma (NCT05538988) | AHS Cancer Control Alberta | 2024-12-01 |
| Drug Screening Using Novel IMD in Renal Cell Carcinoma (NCT05700461) | Oliver Jonas | 2024-12-01 |
| Auto-HSCT-Supported Dose-Dense Chemotherapy with Adebrelimab As First-Line Treatment for ES-SCLC (NCT06597513) | Zhou Chengzhi | 2024-12-01 |
| Preemptive Infusion of Donor Lymphocytes Depleted of TCR + T Cells + CD19+ B Cells Following ASCT (NCT03939585) | Leland Metheny | 2024-12-01 |
| Phase I Study of BM2216 ER vs. Melogabalin Besilate: Safety, PK, and Food Effect in Healthy Adults (NCT06846567) | Zhejiang Anglikang Pharmaceutical Co., Ltd. | 2024-12-01 |
| Study of Airway Inflammatory Responses to Experimental Rhinovirus Infection (NCT03508479) | University of North Carolina, Chapel Hill | 2024-12-01 |
| Clinical Utility and Safety of Human Umbilical Cord Mesenchymal Stem Cell Secretome in Drug Resistant Epilepsy Single Center, Non-randomized, Phase I Clinical Trial (NCT06638970) | Baermed | 2024-12-01 |
| Subjects With Advanced or Metastatic Solid Tumor Malignancies (NCT05474859) | Xenthera, Inc. | 2024-12-01 |
| Intrathecal Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells for Children With Cerebral Palsy (NCT07763028) | Gadjah Mada University | 2024-12-01 |
| A Multiple Ascending Dose Study of PUL-042 in Stem Cell Transplant Recipients (NCT03097796) | Pulmotect, Inc. | 2024-12-01 |
| HY1272 in Patients With Locally Advanced or Metastatic Solid Tumors or Locally Advanced or Metastatic EGFRm+ NSCLC (NCT06218940) | Newsoara Biopharma Co., Ltd. | 2024-12-01 |
| UC-MSC Transplantation for Left Ventricular Dysfunction After AMI (NCT03902067) | Shanghai Life Science & Technology | 2024-12-01 |
| Optimizing Transcranial Magnetic Stimulation for Stimulant Use Disorder (NCT06790576) | University of Minnesota | 2024-12-01 |
| A Single Arm Clinical Study of Dendritic Cell Vaccine Loaded With Circular RNA Encoding Cryptic Peptide for Patients With HER2-negative Advanced Breast Cancer (NCT06530082) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2024-12-01 |
| Study of EPI-003 in Select Nucleos(t)Ide Analogue-Treated, Chronic Hepatitis B Patients (NCT06661148) | Epigenic Therapeutics, Inc | 2024-12-01 |
| A Study to Assess the Relative Bioavailability of Three Immediate-Release Tablet Formulations of ABBV-903 in Healthy Adult Volunteers (NCT06078202) | AbbVie | 2024-12-01 |
| Impact of Recombinant Humanized Type III Collagen on the Immediate and Long-term Effects of Breast Tumor Surgery (NCT06725082) | Peking University People's Hospital | 2024-12-01 |
| A Study of MFA-370 in Patients with Metastatic Urothelial Cancer (NCT05390645) | Ectin Research AB | 2024-12-01 |
| Gene-Environment-Interaction: Influence of the COMT Genotype on the Effects of Different Cannabinoids - a PET Study (NCT02492074) | Central Institute of Mental Health, Mannheim | 2024-12-01 |
| CD70-CAR-NK Cell Therapy for T Cell Lymphoma and Acute Myeloid Leukemia (NCT06696846) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-12-01 |
| Methylglyoxal (MGO) Lowering Cocktail to Reduce Appetite in Obese Individuals (NCT05083546) | University of California, San Francisco | 2024-12-01 |
| A Study to Evaluate the Pharmacokinetics and Safety Between Single Oral Administration of BR3006 and Co-administration of BR3006A, BR3006B and BR3006C in Healthy Adult Volunteers Under Fasting Conditions (NCT06890286) | Boryung Pharmaceutical Co., Ltd | 2024-12-01 |
| Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis (NCT06626984) | Belfast Health and Social Care Trust | 2024-12-01 |
| IIT PH1 KDS-1001 in Patients With CML (NCT04808115) | Duke University | 2024-12-01 |
| AK137 (Bispecific Antibody Targeting CD73 and LAG-3) in Patients With Advanced Malignant Tumors (NCT06691360) | Akeso | 2024-12-01 |
| Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles Infusion Treatment for ARDS (NCT05127122) | Direct Biologics, LLC | 2024-12-01 |
| Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant (NCT06725121) | University Health Network, Toronto | 2024-12-01 |
| Irinotecan Liposomes Combined with Temozolomide and Vincristine in the Treatment of Pediatric Patients with Solid Tumors (NCT06710821) | Yizhuo Zhang | 2024-12-01 |
| CAR-T Technology for Recurrent/Refractory Malignant Hematological and Lymphatic Tumors (NCT06647329) | Mingzhi Zhang | 2024-12-01 |
| Clinical Study of Cord Blood-derived IL-10/IL-15 CD19-CAR NK in the Treatment of Refractory/Relapsed B-cell NHL (NCT06707259) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-12-01 |
| Diclofenac Dose Response Study (NCT06636227) | University of Maryland, Baltimore | 2024-12-01 |
| Exploring Nasal Drop Therapy With Small Extracellular Vesicles for ALS (NCT06598202) | Xuanwu Hospital, Beijing | 2024-12-01 |
| Safety and Feasibility of Human Umbilical Cord Mesenchymal Stem Cell-Derived Secretome in the Treatment of Liver Cirrhosis: a Comprehensive Evaluation of Fibrosis Reduction, Immunomodulation, and Hepatic Regeneration: a Single Center, Randomized, Phase I Clinical Trial (NCT06629909) | Baermed | 2024-12-01 |
| Safety of Cultured Autologous Adult Adipose Derived Mesenchymal Stem Cell Versus Cultured Allogeneic Adult Umbilical-cord Derived Mesenchymal Stem Cell Intrathecal Injection for SCI (NCT05018793) | The Foundation for Orthopaedics and Regenerative Medicine | 2024-12-01 |
| Use of Extracellular Vesicles (EV) for Diabetic Foot Ulcers (NCT06825884) | University of Jordan | 2024-12-01 |
| A Study to Evaluate of PM8002 Combined With PM1009 in Patients With First-line HCC (NCT06584071) | Biotheus Inc. | 2024-12-01 |
| Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma (NCT03811886) | Case Comprehensive Cancer Center | 2024-12-01 |
| Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) (NCT06960369) | The First Affiliated Hospital of Soochow University | 2024-12-01 |
| Linperlisib Combined With EZH2 Inhibitor in Relapsed/Refractory Peripheral T-cell Lymphoma (PTCL) (NCT06712173) | Institute of Hematology & Blood Diseases Hospital, China | 2024-12-01 |
| Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study (NCT06752486) | Research Institute of Ophthalmology, Egypt | 2024-12-01 |
| Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2) (NCT04073433) | Resilient Pharmaceuticals | 2024-12-01 |
| HER2-PET Imaging in HER2-low Breast Cancers (NCT06732336) | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | 2024-12-01 |
| YL-13027 and/or HY-0102 Combined With AG Regimen Chemotherapy for Metastatic Pancreatic Cancer (NCT06662669) | Shanghai YingLi Pharmaceutical Co. Ltd. | 2024-11-30 |
| Efficacy, Safety Profile, and Post-Acne Sequelae of 0.025% Retinoic Acid Cream vs. 0.1% Adapalene Cream in Mild Acne Vulgaris in Fitzpatrick Skin Types III-V (NCT07015931) | Indonesia University | 2024-11-30 |
| Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-T (NCT05617651) | Il-Yang Pharm. Co., Ltd. | 2024-11-30 |
| SYN023 With Rabies Vaccine in Healthy Pediatric Subjects (NCT07342257) | Synermore Biologics (Suzhou) Co., Ltd. | 2024-11-30 |
| A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and Drug-Drug Interaction Study of NX-5948 in Healthy Volunteers (NCT06717269) | Nurix Therapeutics, Inc. | 2024-11-30 |
| The Safety and Efficacy of Coenzyme I for Injection in Promoting Hematopoietic Recovery of Patients After sUCBT (NCT06558253) | Anhui Provincial Hospital | 2024-11-29 |
| Comparison of Diclofenac Systemic Exposure From Two Different Products (AMZ001 and Diclofenac Diethylammonium 1.16% Gel) in Healthy Participants After Repeated Topical Administrations for 7 Days. (NCT06729073) | Amzell | 2024-11-29 |
| Phase 1b, Open-label Study of Tune-401 to Assess Safety, PK and PD in Adults With Chronic Hepatitis B (NCT06671093) | Tune Therapeutics, Inc. | 2024-11-29 |
| Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases (NCT06685042) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2024-11-29 |
| Study of HS235 for Assessing the Pharmacokinetics, Safety, and Pharmacodynamics in Overweight/Obese Healthy Subjects (NCT06714825) | 35Pharma Inc | 2024-11-28 |
| A Comparative Study of the Pharmacokinetics of SIM0718 Injection in Healthy Adult Subjects in China (NCT06701149) | Simcere Pharmaceutical Co., Ltd | 2024-11-28 |
| A Clinical Study of TQB2029 for Injection in Subjects With Multiple Myeloma (NCT06700395) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2024-11-28 |
| Dose-escalation and Food Effect Study of ZT006 in Healthy, Overweight and Obese Participants (NCT07307638) | Beijing QL Biopharmaceutical Co.,Ltd | 2024-11-28 |
| Study of Pazopanib Combined With Palbociclib for Refractory Solid Tumors With Co-amplified in the 11q13(FGF3/4/19/CCND1) (NCT06895733) | Tianjin Medical University Second Hospital | 2024-11-27 |
| A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes (NCT06712680) | Sichuan Huiyu Pharmaceutical Co., Ltd | 2024-11-27 |
| Clinical Study to Evaluate Drug-drug Interaction and Safety After Co-administration of D352 and D794 in Healthy Adult Volunteers (NCT06758661) | Chong Kun Dang Pharmaceutical | 2024-11-27 |
| A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma (NCT06622226) | Ono Pharmaceutical Co., Ltd. | 2024-11-27 |
| A Phase I Study to Investigate the Safety and Tolerability of KGX101 Monotherapy and Combination Therapy With Envafolimab in Advanced or Metastatic Solid Tumor Patients (NCT07260305) | Kangabio AUSTRALIA LTD PTY | 2024-11-27 |
| A Study to Learn How Different Amounts of the Study Medicine Called PF-08049820 Are Tolerated and Act in the Body in Healthy Adults (NCT06686797) | Pfizer | 2024-11-27 |
| Healing Assessment of External Inflammatory Root Resorption After Revascularization Technique of Avulsed Permanent Central Incisor (Case Study) (NCT06785961) | Badr University | 2024-11-27 |
| A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies (NCT06634589) | BeOne Medicines | 2024-11-27 |
| Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer (NCT06236139) | Fred Hutchinson Cancer Center | 2024-11-26 |
| A Study of SPY002-091 in Healthy Volunteers (NCT06672718) | Spyre Therapeutics, Inc. | 2024-11-26 |
| A Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of Briquilimab in Participants With Allergic Asthma (NCT06592768) | Jasper Therapeutics, Inc. | 2024-11-26 |
| A Study to Evaluate the Tolerability, Safety, and Efficacy of an Anti-CD19 CAR-T Product in Patients With B-cell Lymphoproliferative Disorders (NCT06705530) | National Research Center for Hematology, Russia | 2024-11-26 |
| Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies (NCT06343376) | Roswell Park Cancer Institute | 2024-11-26 |
| A Single Dose Study to Assess Adverse Events and How Oral Icalcaprant Moves Through the Body in Healthy Adult Japanese and Han Chinese Participants (NCT06722417) | AbbVie | 2024-11-26 |
| Prophylactic CD45RA-depleted DLI After Haploidentical Transplantation/RIC (NCT05066412) | University Hospital, Geneva | 2024-11-26 |
| A Study of Tetrathiomolybdate (TM) Plus Capecitabine (NCT06134375) | Dartmouth-Hitchcock Medical Center | 2024-11-26 |
| Study on Mass Balance of [14C]HMPL-306（Isocitrate Dehydrogenase Inhibitor） in Healthy Chinese Adult Male Subjects (NCT06671873) | Hutchmed | 2024-11-26 |
| Mezigdomide and Elranatamab for Relapsed and/or Refractory Multiple Myeloma (NCT06645678) | YOUNGIL KOH | 2024-11-26 |
| Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HRS-5965 in Subjects With Hepatic Impairment (NCT06674915) | Chengdu Suncadia Medicine Co., Ltd. | 2024-11-26 |
| Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product MediReg® (NCT06869863) | Lomonosov Moscow State University Medical Research and Educational Center | 2024-11-26 |
| Multicenter, Phase I/II Study to Evaluate the Safety, Tolerability, PK and Efficacy of SCT520FF in Patients With nAMD (NCT06672536) | Sinocelltech Ltd. | 2024-11-26 |
| Evaluating the Safety and Efficacy of BioTTT001 in Patients With Recurrent/Progressive High-grade Glioma. (NCT06763965) | Beijing Bio-Targeting Therapeutics Technology Co., Ltd | 2024-11-26 |
| Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays (NCT06607003) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-11-26 |
| A Trial to Assess Bioavailability of AMG 133 in Participants With Overweight or Obesity (NCT07717814) | Amgen | 2024-11-26 |
| Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases (NCT06411639) | Novartis Pharmaceuticals | 2024-11-25 |
| Phase 1 Single Ascending Dose Study (NCT06934941) | Neuramedy Co. Ltd. | 2024-11-25 |
| Safety and PK of Multiple Doses of MT1988 (NCT06728176) | Monument Therapeutics Limited | 2024-11-25 |
| Safety, Tolerability, and Pharmacokinetics of Single Doses of HC022 in Healthy Subjects. (NCT06657703) | HC Biopharma Inc. | 2024-11-25 |
| Personalized Antisense Oligonucleotide Therapy for A Single Participant With TARDBP ALS (NCT07095712) | n-Lorem Foundation | 2024-11-25 |
| Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development (NCT06379971) | University of Colorado, Denver | 2024-11-25 |
| Creating an Engaging BCI/FES Therapy for Children With Perinatal Stroke Using Social Media (NCT07133347) | University of Calgary | 2024-11-25 |
| Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer (NCT06613100) | Amgen | 2024-11-25 |
| A Study of NP-201 Acetate Injection in Healthy Adult Volunteers and in Patients With Mild-To-Moderate Active Ulcerative Colitis (NCT06681389) | NIBEC Co., Ltd. | 2024-11-25 |
| A Clinical Trial to Evaluate the Safety and Immunogenicity of CH505M5 N197D mRNA-gp160 Followed by CH505 TF mRNA-gp160 in Adults in Overall Good Health Without HIV (NCT06557785) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-11-25 |
| The Safety and Efficacy of Universal CAR-T Cells Targeting BCMA in the Treatment of Refractory NMOSD (NCT06633042) | Bioray Laboratories | 2024-11-25 |
| ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours (NCT06597721) | Adcendo ApS | 2024-11-25 |
| A Phase 1 Study of FZ008-145 in Healthy Subjects. (NCT06685809) | Guangzhou Fermion Technology Co., LTD | 2024-11-25 |
| Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical Trial (NCT06750302) | St. Paul's Hospital, Canada | 2024-11-24 |
| Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102) (NCT06500793) | Ensysce Biosciences | 2024-11-24 |
| TGRX-678 Phase I Oral Pharmacokinetic Study (NCT06697899) | Shenzhen TargetRx Co., Ltd. | 2024-11-24 |
| A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Subcutaneous Injections of SHR-2173 in Patients With Systemic Lupus Erythematosus (NCT06955598) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2024-11-24 |
| Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases (NCT06688799) | Beijing GoBroad Hospital | 2024-11-23 |
| Bioequivalence Study of Iron Sucrose Injection in Healthy Participants (NCT06674486) | Sichuan Huiyu Pharmaceutical Co., Ltd | 2024-11-22 |
| A Study to Learn About if the Study Medicine Called Ibuzatrelvir Changes How the Body Process the Other Medicine Dabigatran Etexilate in Healthy Adults (NCT06693518) | Pfizer | 2024-11-22 |