| A Clinical Study of Enlicitide in Participants With Severe Renal Impairment (MK-0616-032) (NCT06643377) | Merck Sharp & Dohme LLC | 2024-11-22 |
| A Phase I/IIa Study of JAB-23E73 in Patients With Advanced Solid Tumors Harboring KRAS Gene Alteration (NCT06959615) | Jacobio Pharmaceuticals Co., Ltd. | 2024-11-22 |
| A Study to Learn About the Study Medicine Called PF-07905428 in Healthy Participants and Participants With Acne Vulgaris (NCT06671834) | Pfizer | 2024-11-22 |
| A Two-Part Phase 2a Study of RVX000222 in Patients With End-Stage Renal Disease Treated With Hemodialysis (NCT03160430) | Resverlogix Corp | 2024-11-22 |
| Pharmacokinetics and Pharmacodynamics of Two Prolonged-release Formulations of Vamifeport in Healthy Adults (NCT06726863) | CSL Behring | 2024-11-22 |
| Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms (NCT06484075) | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 2024-11-21 |
| Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers (NCT07364838) | Daewon Pharmaceutical Co., Ltd. | 2024-11-21 |
| Phase 1 Study of GC1130A in Patients With Sanfilippo Syndrome Type A (MPS IIIA) (NCT06567769) | GC Biopharma Corp | 2024-11-21 |
| Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors (NCT06666270) | Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd | 2024-11-21 |
| Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies (NCT06458712) | Duke Street Bio Ltd | 2024-11-21 |
| A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration (NCT06660667) | Sanofi | 2024-11-21 |
| A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors (NCT06598371) | M.D. Anderson Cancer Center | 2024-11-21 |
| Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases (NCT06671236) | Novabio Therapeutics | 2024-11-21 |
| A Study in Healthy Subjects to Assess the Safety and Tolerability of a 120-hour Continuous Infusion of M6229 (NCT07285603) | Matisse Pharmaceuticals | 2024-11-21 |
| ORB-021 In Patients With Advanced Solid Tumors (NCT06607939) | Orionis Biosciences Inc | 2024-11-21 |
| A Study of S-740792 in Healthy Adult Study Participants (NCT06724978) | Shionogi | 2024-11-21 |
| A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer (NCT06678659) | Recursion Pharmaceuticals Inc. | 2024-11-21 |
| A Dose Escalating Study of HC002 in Healthy Adult Volunteers (NCT06670274) | Holoclara Aus Pty Ltd | 2024-11-21 |
| Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence (NCT06430541) | University of Colorado, Denver | 2024-11-21 |
| Dexmedetomidine and Magnesium Sulfate in the Reduction Cognitive Dysfunction in Geriatrics (NCT06702488) | Fayoum University | 2024-11-21 |
| 68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC (NCT06649682) | Peking Union Medical College Hospital | 2024-11-21 |
| Feasibility of Accelerated, Personalized rTMS as an Adjuvant for Impulse Control Disorders: a Pilot Study (NCT06639594) | M.D. Anderson Cancer Center | 2024-11-21 |
| Integrated Traditional Chinese Medicine Day Care Program for Metabolic Syndrome (NCT06703788) | Chang Gung Memorial Hospital | 2024-11-20 |
| Effect of Adding Different Concentrations of Dexmedetomidine to Bupivacaine in Caudal Block for Pediatrics (NCT06668220) | Assiut University | 2024-11-20 |
| Study of Trivalent and Bivalent (Types 1 & 2) Novel Oral Poliomyelitis Vaccines (NCT06137664) | PATH | 2024-11-20 |
| Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy (NCT06065371) | Henry Ford Health System | 2024-11-20 |
| A First-in-human Study to Investigate Safety and Tolerability of SAR446959 in Participants With Osteoarthritis of the Knee (NCT06704932) | Sanofi | 2024-11-20 |
| An Open-label, DDI Study to Investigate the Effects of Amlitelimab on the PK of Selected Cytochrome P450 Substrates (NCT06686628) | Sanofi | 2024-11-20 |
| To Evaluate the Pharmacokinetics and Safety of TQD3606 for Injection in Subjects With Renal Insufficiency (NCT06672276) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-11-20 |
| A Prospective Clinical Study of the Combination Therapy of Obutinib or Decitabine with Rituximab, Cyclophosphamide, and Prednisone for the Primary Treatment of Elderly Patients with Newly Diagnosed Diffuse Large B-cell Lymphoma (NCT06683885) | Mingzhi Zhang | 2024-11-20 |
| Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection (NCT06456424) | University of Calgary | 2024-11-20 |
| A Study to Characterize Single and Repeat Dose Pharmacokinetics of Tebipenem-Pivoxil-Hydrobromide (TBP-PI-HBr) and Its Major Metabolite (SPR1349) in Healthy Participants (NCT06727136) | Spero Therapeutics | 2024-11-20 |
| NTLA-3001 in Adults with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease (NCT06622668) | Intellia Therapeutics | 2024-11-20 |
| A Study Assessing KB304 for the Treatment of Wrinkles in Women (NCT06724900) | Krystal Biotech, Inc. | 2024-11-20 |
| A Research Study Comparing Different Ways of Increasing the Dose of NNC0519-0130 in Participants With Overweight or Obesity (NCT06718998) | Novo Nordisk A/S | 2024-11-20 |
| Clinical Study of CVL006 Injection in Advanced Solid Tumors (NCT06621615) | Convalife (Shanghai) Co., Ltd. | 2024-11-20 |
| Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Neoadjuvant Triple-negative Breast Cancer (NCT06631092) | NEC Bio B.V | 2024-11-20 |
| Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma (NCT06191133) | Lindsay Ferguson, MD | 2024-11-20 |
| Study of a Combination Vaccine Comprised of Different Recombinant Spike Antigen Levels of a Matrix-M Adjuvanted Recombinant COVID-19 Vaccine and High-Dose Inactivated Influenza Vaccine in Adult Participants 50 Years of Age and Older (NCT06695117) | Sanofi | 2024-11-19 |
| Patient Controlled Administration of Liquid Acetaminophen (NCT06498713) | Yale University | 2024-11-19 |
| Low Intensity Focused Ultrasound Modulation of Thalamic Nuclei for Central Neuropathic Pain. (NCT06978764) | University of Sao Paulo | 2024-11-19 |
| HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML (NCT06594445) | Masonic Cancer Center, University of Minnesota | 2024-11-19 |
| Allogeneic NKG2DL-targeting CAR γδ T Cells (CTM-N2D) in Advanced Cancers (ANGELICA) (NCT05302037) | CytoMed Therapeutics Pte Ltd | 2024-11-19 |
| Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion (NCT06439485) | M.D. Anderson Cancer Center | 2024-11-19 |
| A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age (NCT06702449) | GlaxoSmithKline | 2024-11-19 |
| A Second Psilocybin Group Therapy for the Treatment of Cancer-Related Anxiety in Partial Responders With Metastatic Cancer (NCT06644170) | University of Washington | 2024-11-19 |
| Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy (NCT02531880) | National Institute of Neurological Disorders and Stroke (NINDS) | 2024-11-19 |
| A Study to See How Well and How Safely Different Treatments Work in a Group of Participants With Non-Small Cell Lung Cancer (NSCLC) (NCT06624059) | Hoffmann-La Roche | 2024-11-18 |
| A Study to Investigate the Pharmacokinetics, Safety and Tolerability of AZD5462 in Participants With Renal Impairment (NCT06661733) | AstraZeneca | 2024-11-18 |
| Mts105 for Advanced Hepatocellular Carcinoma (NCT06689540) | Shen Lin | 2024-11-18 |
| Study of a Combination Vaccine Comprised of Different Recombinant Spike Antigen Levels of a Matrix-M Adjuvanted Recombinant COVID-19 Vaccine and Recombinant Influenza Vaccine in Adult Participants 50 Years of Age and Older (NCT06695130) | Sanofi | 2024-11-18 |
| A Study to Evaluate Single-dose of HB0056 in Healthy Adult Participants (NCT06612970) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2024-11-18 |
| A First-time in Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK4528287 in Healthy Participants (NCT06681181) | GlaxoSmithKline | 2024-11-18 |
| A SINGLE CENTER, 5-PART STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF GAL-101 SALT IN HEALTHY ADULT AND ELDERLY PARTICIPANTS (NCT07780604) | Galimedix Therapeutics Inc | 2024-11-18 |
| Intracochlear Application of VSF1.01 for the Reduction of Cochlear Implant Surgery Related Trauma (NCT06545175) | Hannover Medical School | 2024-11-18 |
| A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK (NCT06372821) | University College, London | 2024-11-18 |
| A Study of RPT1G After Single and Multiple Doses in Healthy Adult Participants (NCT06667765) | Remedy Plan, Inc. | 2024-11-18 |
| A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease (NCT06603246) | Genentech, Inc. | 2024-11-18 |
| A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of AZD4144 in Participants With Severe Renal Impairment, End-stage Kidney Disease, and in Healthy Participants (NCT06693765) | AstraZeneca | 2024-11-18 |
| To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With Locally Advanced or Metastatic Solid Tumors (NCT06752681) | Day One Biopharmaceuticals, Inc. | 2024-11-18 |
| A Study of SPY002-072 in Healthy Volunteers (NCT06622070) | Spyre Therapeutics, Inc. | 2024-11-18 |
| CAR-T Cell Therapy Targeting GPC3 in Patients with Advanced GPC3-Positive Hepatocellular Carcinoma (NCT06641453) | Chinese PLA General Hospital | 2024-11-15 |
| Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with Glioblastoma (NCT05773664) | City of Hope Medical Center | 2024-11-15 |
| Efficacy, Safety and Immunological Evaluation of Upadacitinib for Relapsing Polychondritis (NCT06873100) | Peking University People's Hospital | 2024-11-15 |
| A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer (NCT06678269) | Memorial Sloan Kettering Cancer Center | 2024-11-15 |
| Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML (NCT06158828) | Washington University School of Medicine | 2024-11-15 |
| A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia (NCT05757310) | City of Hope Medical Center | 2024-11-15 |
| Clinical Trial of Lyophilized Haemophilus Influenzae Type b Conjugate Vaccine (NCT06621654) | CanSino Biologics Inc. | 2024-11-15 |
| Tolerance and Effectiveness of C14 on HPV Infection (NCT06672653) | MGB Pharma | 2024-11-15 |
| A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors (NCT05828303) | Turning Point Therapeutics, Inc. | 2024-11-15 |
| A Bioavailability Study of Nilotinib in Healthy, Adult, Human Subjects Under Fasted Conditions. (NCT07138378) | Xspray Pharma AB | 2024-11-15 |
| Bortezomib Combined with PD-1 MAb and MFOLFIRINOX for Metastatic Pancreatic Cancer (NCT06572813) | First Affiliated Hospital of Zhejiang University | 2024-11-15 |
| A Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Divarasib in Healthy Participants (NCT06690138) | Genentech, Inc. | 2024-11-15 |
| Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention (NCT06281834) | Brigham and Women's Hospital | 2024-11-15 |
| 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours (NCT06630260) | Institute of Cancer Research, United Kingdom | 2024-11-15 |
| A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors (NCT06619587) | Genentech, Inc. | 2024-11-14 |
| First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors (NCT06644755) | Daiichi Sankyo | 2024-11-14 |
| Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B (NCT06680232) | Precision BioSciences, Inc. | 2024-11-14 |
| A Phase I Clinical Trial Evaluating the Safety, Tolerability and Pharmacokinetics of AAPB for Injection (NCT06679998) | Jiangsu Kanion Pharmaceutical Co., Ltd | 2024-11-14 |
| A Clinical Research About CD70-targeted CAR-NKT Cells Therapy in Subjects with Advanced Malignant Solid Tumors (NCT06728189) | Peking University Cancer Hospital & Institute | 2024-11-14 |
| A Study to Investigate the Safety, Tolerability, PK, and PD of CKD-508 in Healthy Participants (NCT06727396) | Chong Kun Dang Pharmaceutical | 2024-11-14 |
| A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE) (NCT06422923) | Neurona Therapeutics | 2024-11-14 |
| Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL (NCT06880913) | Peking University People's Hospital | 2024-11-14 |
| SCD Stem Cell Mobilization and Apheresis Using Motixafortide (NCT06442761) | St. Jude Children's Research Hospital | 2024-11-14 |
| Safety and Efficacy of SYHA1813 Single Agent or in Combination With Different Regimens in Unresectable Locally Advanced or Metastatic Solid Tumors. (NCT06682611) | Shanghai Runshi Pharmaceutical Technology Co., Ltd | 2024-11-13 |
| A Study to Assess Change in How Oral Icalcaprant With Itraconazole Moves Through the Body in Healthy Adult Participants (NCT06722430) | AbbVie | 2024-11-13 |
| A Study of FC084CSA in Combination of Tislelizumab in Patients With Advanced Malignant Solid Tumors (NCT06499350) | FindCure Biosciences (ZhongShan) Co., Ltd. | 2024-11-13 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection (NCT07024641) | GigaGen, Inc. | 2024-11-13 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ID110521156 in Healthy Adult Subjects (NCT06635226) | IlDong Pharmaceutical Co Ltd | 2024-11-13 |
| A Study in Healthy People to Test How 2 Different Formulations of BI 690517 Are Taken up in the Body and How Probenecid Influences the Amount of BI 690517 in the Blood (NCT06647810) | Boehringer Ingelheim | 2024-11-13 |
| A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia (NCT06859073) | Novo Nordisk A/S | 2024-11-13 |
| RE104 Clinical Lactation Study (NCT06659263) | Reunion Neuroscience Inc | 2024-11-13 |
| Propranolol Hydrochloride in Combination With Sintilimab and Platinum-based Chemotherapy for Treatment of Advanced Non-small Cell Lung Cancer (NCT05979818) | Second Xiangya Hospital of Central South University | 2024-11-13 |
| A Study of SHR-3821 Injection in Subjects With Advanced Solid Tumors (NCT06618651) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2024-11-13 |
| Safety and Immunogenicity of Recombinant RSV Vaccine (CHO Cell) in Healthy Subjects Aged 18 Years and Above (NCT06642558) | MAXVAX Biotechnology Limited Liability Company | 2024-11-13 |
| Phase I Study of Ropivacaine, Clonidine, and Betamethasone Combination for Sciatic Nerve Block in the Popliteal Region (NCT06781632) | PHARMAFINA | 2024-11-13 |
| Clinical Trial of CD123-targeted CAR-NK Therapy for Relapse/refractory AML or BPDCN (NCT06690827) | Chongqing Precision Biotech Co., Ltd | 2024-11-13 |
| THE-0504 in Patients With Solid Tumors (NCT07646106) | Thena Biotech S.r.l. | 2024-11-13 |
| A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors (NCT06685068) | Genmab | 2024-11-13 |
| LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF) (NCT06462729) | Locate Bio Pty Ltd | 2024-11-12 |