| A First-in-Human Single and Multiple Ascending Dose Study of MT-501 (NCT06762457) | Mirador Therapeutics, Inc. | 2024-12-11 |
| Safety Study of TPX-121 on Nasolabial Folds (NCT06533540) | Tego Science, Inc. | 2024-12-11 |
| Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma (NCT06784648) | BioInvent International AB | 2024-12-11 |
| The Safety and Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy for Peritoneal Metastatic Adenocarcinoma (NCT06743867) | Guangdong Provincial People's Hospital | 2024-12-11 |
| A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of Single Ascending Dose of GSK4771261 in Healthy Participants and Participants With Autosomal Dominant Polycystic Kidney Disease (NCT06734234) | GlaxoSmithKline | 2024-12-11 |
| A Study for the Treatment of Metastatic Prostate Cancer With HRS-1167 Tablets Combined With Abiraterone Acetate Tablets and Prednisone (NCT06689163) | Jiangsu HengRui Medicine Co., Ltd. | 2024-12-11 |
| A Study to Learn if the Study Medicine Called Itraconazole and if Food Changes How the Body Processes the Other Study Medicine Called PF 07258669 in Older Adults or Healthy Adults (NCT06706869) | Pfizer | 2024-12-11 |
| Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors (NCT06724016) | Hanmi Pharmaceutical Company Limited | 2024-12-11 |
| A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST) (NCT06630234) | Deciphera Pharmaceuticals, LLC | 2024-12-10 |
| Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of MPD-1 in Patients With Advanced Solid Tumor (NCT06944457) | Pharosgen Co.,Ltd | 2024-12-10 |
| Safety, Tolerability, and Pharmacokinetic Profile of Grammidin, a Metered Dose Topical Spray in Healthy Volunteers (NCT06859281) | Valenta Pharm JSC | 2024-12-10 |
| Phase 1 Clinical Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP212525 in Healthy Volunteers (NCT06736587) | Daewoong Pharmaceutical Co. LTD. | 2024-12-10 |
| Safety and Immunogenicity Study of Self-Amplifying RNA Pandemic Influenza Vaccine in Adults (NCT06602531) | Arcturus Therapeutics, Inc. | 2024-12-10 |
| Blinding and Adverse Effects of Ultrasonic Vagus Nerve Stimulation (U-VNS) (NCT07091812) | University of Nottingham | 2024-12-10 |
| A Trial to Evaluate Interactions Between Antiemetic Medication and AMG 133 in Participants Living With Overweight or Obesity (NCT07310563) | Amgen | 2024-12-10 |
| Study of 68Ga-R10602 (NCT06745804) | Radionetics Oncology | 2024-12-10 |
| Role of Pericapsular Nerve Block Using Dexmedetomidine and Bupivacaine in Improving the Outcome of Patients Undergoing Hip Surgery Under Spinal Anesthesia (NCT07149168) | Ain Shams University | 2024-12-10 |
| A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene. (NCT06704724) | Pfizer | 2024-12-10 |
| A Study to Evaluate the Relative Bioavailability of Two Different Pimicotinib Capsules in Healthy Subjects (NCT06694948) | Abbisko Therapeutics Co, Ltd | 2024-12-10 |
| A Clinical Study of SHR-3276 for Injection in Patients With Advanced Malignant Tumors (NCT06643754) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2024-12-10 |
| KF2024#1-trial: Esketamine Interaction Study (NCT06726382) | Helsinki University Central Hospital | 2024-12-09 |
| Clinical Trial of TQB3002 in Patients With Advanced Cancers (NCT06662760) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-12-09 |
| Safety, Tolerability, and Pharmacokinetic Profile of Grammidin With Anesthetic, a Metered Dose Topical Spray in Healthy Volunteers (NCT06857890) | Valenta Pharm JSC | 2024-12-09 |
| A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors (NCT06625593) | BeOne Medicines | 2024-12-09 |
| A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Hematologic Malignancies (NCT06645886) | Kumquat Biosciences Inc. | 2024-12-09 |
| ETC-159 In Combination With Pembrolizumab In Advanced MSS/pMMR Ovarian Cancers (NCT06513624) | National University Hospital, Singapore | 2024-12-09 |
| Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC (NCT06663306) | Shanghai Chest Hospital | 2024-12-09 |
| Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial) (NCT06723106) | Chugai Pharmaceutical | 2024-12-09 |
| PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF (NCT06683612) | Contineum Therapeutics | 2024-12-09 |
| Study to Evaluate Safety and Immunogenicity of a Pandemic Flu H5 mRNA Vaccine in Healthy Adults Aged 18 Years and Older (NCT06727058) | Sanofi Pasteur, a Sanofi Company | 2024-12-09 |
| A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease. (NCT06675175) | AstraZeneca | 2024-12-09 |
| A Study to Assess the Safety, Pharmacokinetics, and Tolerability of ABI-1179 in Healthy Subjects and in Subjects Seropositive for HSV-2 With Recurrent Genital Herpes (NCT06698575) | Assembly Biosciences | 2024-12-08 |
| Blinatumomab in Refractory Active Childhood Systemic Lupus Erythematosus (NCT06789107) | Mao Jianhua | 2024-12-08 |
| A Study to Evaluate BMS-986278 in Participants With Normal Renal Function, Severe Renal Impairment, or End-Stage Renal Disease on Intermittent Hemodialysis (NCT06723535) | Bristol-Myers Squibb | 2024-12-07 |
| Safety for Home Administration of Microdose Psilocybin Use (NCT06450210) | Johns Hopkins University | 2024-12-06 |
| Evaluation of Empagliflozin vs Standard Care in Veterans With Prediabetes (NCT06828731) | Charles George VA Medical Center | 2024-12-06 |
| A Study to Evaluate HB0034 in Healthy Chinese Adult Participants (NCT06716151) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2024-12-06 |
| A Drug-Drug Interaction Study of Orforglipron (LY3502970) With Quinidine in Healthy Participants (NCT06704763) | Eli Lilly and Company | 2024-12-06 |
| Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine (NCT05962229) | University of California, San Francisco | 2024-12-06 |
| A Study to Assess Nomlabofusp in Adolescents and Children With Friedreich's Ataxia (NCT06681766) | Larimar Therapeutics, Inc. | 2024-12-06 |
| A Study of Olomorasib (LY3537982) in Participants With Hepatic Impairment and Healthy Participants (NCT06719128) | Eli Lilly and Company | 2024-12-06 |
| A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of a Single Dose of Donzakimig in Healthy Chinese and Japanese Participants (NCT06716879) | UCB Biopharma SRL | 2024-12-06 |
| A Phase 1/2, Dose-Exploration Study to Evaluate the Safety and Efficacy of BEAM-301 in Patients With Glycogen Storage Disease Type Ia (GSDIa) (NCT06735755) | Beam Therapeutics Inc. | 2024-12-06 |
| Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma (NCT06465316) | National Cancer Institute (NCI) | 2024-12-06 |
| IB-T101 Injection for Treatment of Patients With Advanced Clear Cell Renal Cell Carcinoma (NCT06819293) | Grit Biotechnology | 2024-12-06 |
| Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant (NCT06575296) | City of Hope Medical Center | 2024-12-06 |
| Revumenib in Combination With 7+3 + Midostaurin in AML (NCT06313437) | Richard Stone, MD | 2024-12-06 |
| Study of SIM0508 Alone and in Combination in Patients With Advanced Solid Tumors (NCT06686745) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2024-12-06 |
| Study of SC-102 in Patients With Advanced Solid Tumors (NCT06710158) | Tianjin ConjuStar Biologics Co., Ltd. | 2024-12-05 |
| A Trial in Healthy Adult Participants to Evaluate the Safety, Tolerability, and Behavior in the Body of TBD11 (NCT06707142) | Gates Medical Research Institute | 2024-12-05 |
| Identification of New Tools for Predicting Natural Metabolic Performance of the Liver (NCT07014930) | Caroline Samer | 2024-12-05 |
| Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer (NCT06639724) | University of California, San Diego | 2024-12-05 |
| A Study to Evaluate the Pharmacokinetics and Safety Between Single Oral Administration of BR3006 and Co-administration of BR3006A, BR3006B and BR3006C in Healthy Adult Volunteers Under Fed Conditions (NCT06890299) | Boryung Pharmaceutical Co., Ltd | 2024-12-05 |
| Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors (NCT06650163) | Jonsson Comprehensive Cancer Center | 2024-12-05 |
| A Study to Investigate the Blood Concentrations of 4 Different Oral Doses of Zibotentan in Healthy Non-Asian and Japanese Participants (NCT06715670) | AstraZeneca | 2024-12-05 |
| Impact of PEG Bowel Preparation on Gut Microbiome Composition Recovery (NCT06831539) | Centre hospitalier de l'Université de Montréal (CHUM) | 2024-12-05 |
| CAR T-cell Therapy Targeting CD19 and BCMA in Patients with AIHA Who Have Failed ≥3 Lines of Therapy. (NCT06733610) | Institute of Hematology & Blood Diseases Hospital, China | 2024-12-05 |
| A Study of Aumolertinib in European Participants With Non-Small Cell Lung Cancer (NCT07130916) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2024-12-05 |
| A Study to Evaluate Safety, Tolerability, and Immunogenicity of V350A and V350B in Healthy Participants (V350-001). (NCT06655324) | Merck Sharp & Dohme LLC | 2024-12-05 |
| Continuous Ketone Monitoring in People With Type 1 Diabetes Using SGLT2 Inhibitors (NCT06753994) | McGill University | 2024-12-05 |
| A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer (NCT06685718) | BeOne Medicines | 2024-12-05 |
| Comparison of the Safety, Efficacy and Pharmacokinetics of DehydraTECH -CBD and DehydraTECH-GLP1 Agonists Alone or in Combination, in Overweight or Obese, Pre- and Type 2 Diabetic Participants (NCT06648031) | Lexaria Bioscience Corp. | 2024-12-04 |
| To Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BAR502 in Healthy Subjects (NCT06705998) | BAR Pharmaceuticals s.r.l. | 2024-12-04 |
| Safety, Tolerability, and Pharmacokinetics of a Single or Multiple Ascending Doses of CPX101 (NCT06545162) | Guangzhou Chia Tai Innovative Pharmaceutical Co., Ltd. | 2024-12-04 |
| A Study to Assess Drug-drug Interaction of ZX008 in Healthy Male and Female Study Participants (NCT06679413) | UCB BIOSCIENCES, Inc. | 2024-12-04 |
| Venetoclax in Combination With Azacitidine (VEN/AZA) Followed by Donor Lymphocyte Infusion (DLI) for Patients With Very High-Risk Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Cell Transplant (HCT) (NCT06158100) | Antonio M Jimenez Jimenez | 2024-12-04 |
| First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor. (NCT06603844) | Corbus Pharmaceuticals Inc. | 2024-12-04 |
| BeCoMe-9: A Clinical Study of BE-101 for the Treatment of Adults With Moderately Severe or Severe Hemophilia B (NCT06611436) | Be Biopharma | 2024-12-04 |
| Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function (NCT06623630) | Washington University School of Medicine | 2024-12-04 |
| Comparison of B-cell Depletion by Rituximab and Anti-CD 19 CAR-T Therapy in Patients With Rheumatoid Arthritis (NCT06475495) | Charite University, Berlin, Germany | 2024-12-04 |
| A Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of MegaLT Injection for Treating Refractory Thrombocytopenia Following Radiotherapy, Chemotherapy, or Transplantation. (NCT06534255) | Anhui Provincial Hospital | 2024-12-04 |
| Study on Human Bioequivalence of Triprerelin Acetate for Injection (NCT06683066) | The Affiliated Hospital of Qingdao University | 2024-12-04 |
| A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes Mellitus (NCT06700538) | Arrowhead Pharmaceuticals | 2024-12-04 |
| Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer (NCT06833866) | The Methodist Hospital Research Institute | 2024-12-04 |
| A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide or in Combination With Pomalidomide for Multiple Myeloma (NCT06768489) | Janssen Research & Development, LLC | 2024-12-04 |
| Single Dose Oral Bioequivalence Study of Bempedoic Acid 180 mg Film Coated Tablet and Nilemdo® (Bempedoic Acid) 180 mg Film-coated Tablets in Healthy Adult Human Subjects Under Fasting Conditions. (NCT06923956) | Humanis Saglık Anonim Sirketi | 2024-12-04 |
| Luveltamab Tazevibulin (STRO-002) in Infants and Children < 12 Years of Age With Relapsed/Refractory CBFA2T3::GLIS2 AML (NCT06679582) | Sutro Biopharma, Inc. | 2024-12-04 |
| A Clinical Study of TQC3721 Inhalation Powder in Patients With Chronic Obstructive Pulmonary Disease (NCT06748079) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-12-03 |
| A Study to Learn How Different Amounts of the Study Medicine Called PF-07941944 Are Tolerated in the Body of Healthy Adults. (NCT06920498) | Pfizer | 2024-12-03 |
| Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma (NCT06562673) | Shanghai 6th People's Hospital | 2024-12-03 |
| A Study to Assess the Concentration of Rozanolixizumab in the Breast Milk of Healthy Lactating Women (NCT06720714) | UCB Biopharma SRL | 2024-12-03 |
| Pharmacokinetics, Safety and Immunogenicity of RPH-104 at a New Dosage and Different Doses Via Single Subcutaneous and Intravenous Administration in Healthy Volunteers (NCT07206043) | R-Pharm International, LLC | 2024-12-03 |
| A Study on How NNC0174-1213 Works in People With Overweight or Obesity. (NCT06719011) | Novo Nordisk A/S | 2024-12-03 |
| A Study to Evaluate the Absorption, Metabolism, And Excretion Of Orally Administered [14C]-EDG-7500 (NCT06738836) | Edgewise Therapeutics, Inc. | 2024-12-03 |
| A Safety and Efficacy of Intrathecally Administered ION283 in Patients With Lafora Disease (NCT06609889) | Berge Minassian | 2024-12-03 |
| Safety, Tolerability, and Dose Response of VNA-318 in Healthy Males (NCT06721091) | VANDRIA | 2024-12-03 |
| Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma (NCT06190249) | James Isaacs, MD | 2024-12-02 |
| A Phase I Study to Evaluate the Safety and Drug Allergy of HLB3-002 in Healthy Volunteers (NCT06713317) | Huonslab Co., Ltd. | 2024-12-02 |
| Evaluation of 626 in Healthy Adult Subjects (NCT06674525) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2024-12-02 |
| Tuberoplasty Versus Balloon Spacer (NCT06735170) | University of Minnesota | 2024-12-02 |
| Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD) (NCT06358430) | M.D. Anderson Cancer Center | 2024-12-02 |
| Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine (NCT06821100) | The Methodist Hospital Research Institute | 2024-12-02 |
| A Phase I Clinical Study of a Single Subcutaneous Injection of HRS-5632 in Healthy Subjects (NCT06732154) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2024-12-02 |
| RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM) (NCT06389591) | University of Florida | 2024-12-02 |
| A Study of LY4060874 in Healthy Participants (NCT06709820) | Eli Lilly and Company | 2024-12-02 |
| A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or Obesity (NCT06716307) | Novo Nordisk A/S | 2024-12-02 |
| Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant (NCT05457959) | Jonsson Comprehensive Cancer Center | 2024-12-01 |
| Phase I/II Randomized Clinical Trial of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells Systemic Infusion in Severe Systemic Sclerosis (NCT06722105) | Assistance Publique - Hôpitaux de Paris | 2024-12-01 |
| A Clinical Study on Co-transplantation of Autologous Limbal Stem Cells and Corneal Stromal Stem Cells to Repair Corneal Injury (NCT06700655) | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2024-12-01 |
| Histomorphometric and Radiographic Evaluation of Bone Following Maxillary Sinus Augmentation (NCT06700772) | Cairo University | 2024-12-01 |