| Dose-Escalation, Safety and Pharmacokinetic Study of IC14 in Motor Neurone Disease (NCT03487263) | Implicit Bioscience | 2017-10-01 |
| Virtual Seating Coach on Power Wheelchairs of Persons With Amyotrophic Lateral Sclerosis (ALS) (NCT05742828) | Wake Forest University Health Sciences | 2017-09-20 |
| Rapamycin Treatment for ALS (NCT03359538) | Azienda Ospedaliero-Universitaria di Modena | 2017-09-19 |
| Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants (NCT03237741) | Genentech, Inc. | 2017-08-07 |
| Peripheral Neurofilament Levels and Amyotrophic Lateral Sclerosis (NCT04455542) | Peking University Third Hospital | 2017-08-01 |
| A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT03160898) | Cytokinetics | 2017-07-24 |
| A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria (NCT03613038) | University of Missouri-Columbia | 2017-07-15 |
| Open-label Clinical Trial of Lacosamide in ALS (NCT03186040) | Chiba University | 2017-07-13 |
| Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS) (NCT03068754) | Mallinckrodt | 2017-06-22 |
| MIROCALS: Modifying Immune Response and OutComes in ALS (NCT03039673) | Centre Hospitalier Universitaire de Nīmes | 2017-06-19 |
| A Study of Protein Metabolism, Microbiome and Investigational Probiotic Use in Patients With ALS (NCT03324399) | Avera McKennan Hospital & University Health Center | 2017-06-01 |
| Delineating Swallowing Impairment and Decline in ALS (NCT02962050) | University of Florida | 2017-05-31 |
| The Effect of RNS60 on ALS Biomarkers (NCT03456882) | Mario Negri Institute for Pharmacological Research | 2017-05-30 |
| Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Validation Study (NCT03579017) | Haukeland University Hospital | 2017-05-01 |
| Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Prospective Cohort Study (NCT03578796) | Haukeland University Hospital | 2017-05-01 |
| ALS Study Determining Various Biomarkers and Strength Comparison After Exercise (NCT03201991) | University of Kansas Medical Center | 2017-05-01 |
| Cognitive Consequences of an Activation of the Cortical Drive to Breath (VENTIPSY) (NCT03095729) | Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil | 2017-04-26 |
| Trial of Amivita in Amyotrophic Lateral Sclerosis (NCT03103815) | Wujin People's Hospital | 2017-04-24 |
| CC100: Phase 1 Multiple-Dose Safety and Tolerability in Subjects With ALS (NCT03049046) | Chemigen, LLC | 2017-04-07 |
| Interactions Between Neurostimulation and Physical Exercise (NCT03076632) | Bronx VA Medical Center | 2017-04-01 |
| CNS10-NPC-GDNF for the Treatment of ALS (NCT02943850) | Cedars-Sinai Medical Center | 2017-04-01 |
| A Pilot Study of the Utility of 3D Printed Masks for ALS Subjects (NCT03519880) | University of Michigan | 2017-03-14 |
| NeuRx Diaphram Pacing System (DPS) Use in Amyotrophic Lateral Sclerosis (ALS) (NCT03034317) | Synapse Biomedical | 2017-02-02 |
| Safety/Efficacy Study of 2nd Cycle Treatment After 6 Months of 1st Cycle HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in ALS (NCT03214146) | Hanyang University Seoul Hospital | 2017-02-01 |
| A Clinical Trial to Evaluate the Safety and Efficacy of Fycompa in Subjects With Amyotrophic Lateral Sclerosis (ALS) (NCT03020797) | Stony Brook University | 2017-01-12 |
| EH301 for the Treatment of ALS (NCT03489200) | Elysium Health | 2017-01-01 |
| Amyotrophic Lateral Sclerosis: a New Paradigm (NCT03073239) | Conde, Bebiana, M.D. | 2016-12-01 |
| A Patient Centric Motor Neuron Disease Activities of Daily Living Scale (NCT02852278) | University of South Florida | 2016-12-01 |
| Phase 1 Dose Escalation and PK Study of Cu(II)ATSM in ALS/MND (NCT02870634) | Collaborative Medicinal Development Pty Limited | 2016-11-16 |
| Safety and Tolerability of Antiretroviral (Triumeq) in Patients With Amyotrophic Lateral Sclerosis (ALS). (NCT02868580) | Neuroscience Trials Australia | 2016-10-01 |
| Environmental Exposure and Neurological Diseases Questionnaire (NCT02916966) | Dartmouth-Hitchcock Medical Center | 2016-10-01 |
| Novel MRI Biomarkers for Monitoring Disease Progression in ALS (NCT03362658) | University of Alberta | 2016-10-01 |
| Study of Two Intrathecal Doses of Autologous Mesenchymal Stem Cells for Amyotrophic Lateral Sclerosis (NCT02917681) | University of Sao Paulo General Hospital | 2016-09-01 |
| Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron Disease (NCT03067857) | Stem Cells Arabia | 2016-09-01 |
| Efficacy and Safety of Plasma Exchange With Albutein® 5% in Participants With Amyotrophic Lateral Sclerosis (NCT02872142) | Grifols Therapeutics LLC | 2016-08-29 |
| Safety and Efficacy Study of NP001 in Patients With Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation (NCT02794857) | Neuraltus Pharmaceuticals, Inc. | 2016-08-29 |
| Laughter Therapy Effects on Mood, Stress and Self-efficacy in People With Neurological Diseases. (NCT02750982) | Brown, Theodore R., M.D., MPH | 2016-07-01 |
| Effect of MD1003 in Amyotrophic Lateral Sclerosis (NCT03114215) | MedDay Pharmaceuticals SA | 2016-06-29 |
| Evaluation of Microglial Activation in ALS With [18F]PBR06 (Peripheral Benzodiazepine Receptor-06) PET (NCT03876002) | Molecular NeuroImaging | 2016-06-28 |
| Randomized, Double-blind, Safety and Efficacy of Recombinant Human Erythropoietin in Amyotrophic Lateral Sclerosis (NCT03835507) | Hanyang University Seoul Hospital | 2016-06-20 |
| Neurologic Stem Cell Treatment Study (NCT02795052) | MD Stem Cells | 2016-06-01 |
| Amyotrophic Lateral Sclerosis and the Innate Immune System (NCT02869048) | Rigshospitalet, Denmark | 2016-06-01 |
| A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis (NCT02655614) | Genentech, Inc. | 2016-05-31 |
| A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Literal Sclerosis (ALS) (NCT02714036) | MediciNova | 2016-05-06 |
| Treatment of Intravenous Infusion Plasma in Amyotrophic Lateral Sclerosis (NCT04454840) | Peking University Third Hospital | 2016-05-01 |
| Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS) (NCT02710162) | University of Florida | 2016-04-01 |
| Respiratory Strength Training in Persons With Amyotrophic Lateral Sclerosis (ALS) (NCT02710110) | University of Florida | 2016-04-01 |
| Anti-Cholinergic Receptors Antibodies, Autonomic Profile and Dysautonomia Symptoms in PAF, ALS and POTS (DISAUT-AB) (NCT04875949) | Istituto Clinico Humanitas | 2016-04-01 |
| Muscular Biomarkers in Amyotrophic Lateral Sclerosis (NCT02670226) | University Hospital, Tours | 2016-03-29 |
| The Use of Airway Clearance Devices in ALS (NCT02682030) | Cedars-Sinai Medical Center | 2016-03-01 |
| Tongue Strength in Amyotrophic Lateral Sclerosis (ALS) (NCT02665663) | Assistance Publique Hopitaux De Marseille | 2016-02-01 |
| Longitudinal Study of Innate Lymphoid Cells in Peripheral Blood in ALS (NCT03090932) | University of Michigan | 2016-01-18 |
| Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS) (NCT02460679) | PTC Therapeutics | 2016-01-14 |
| DESIPHER_Speech Degradation as an Indicator of Physiological Degeneration in ALS (NCT02675075) | VA Office of Research and Development | 2016-01-01 |
| Repeated Mesenchymal Stem Cell Injections in ALS (NCT04821479) | Hadassah Medical Organization | 2016-01-01 |
| Answer ALS: Individualized Initiative for ALS Discovery (NCT02574390) | Johns Hopkins University | 2015-12-01 |
| Therapeutic Treatment of Amyotrophic Lateral Sclerosis (NCT02881476) | University of Warmia and Mazury | 2015-11-01 |
| A Trial of Tocilizumab in ALS Subjects (NCT02469896) | Barrow Neurological Institute | 2015-11-01 |
| Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Patients With Amyotrophic Lateral Sclerosis (NCT02881489) | University of Warmia and Mazury | 2015-11-01 |
| Registry Study of Assistive Devices, Medicines and Healthcare Measures in ALS, SMA and Other Neurological Diseases. (NCT05852418) | Ambulanzpartner Soziotechnologie APST GmbH | 2015-10-30 |
| Intraspinal Transplantation of Autologous ADRC in ALS Patients (NCT03296501) | Mossakowski Medical Research Centre Polish Academy of Sciences | 2015-10-13 |
| Predict to Prevent Frontotemporal Lobar Degeneration (FDT) and Amyotrophic Lateral Sclerosis (ALS) (NCT02590276) | Assistance Publique - Hôpitaux de Paris | 2015-10-08 |
| Evaluating the Potential of the Diet as Disease Modifier in Amyotrophic Lateral Sclerosis (JERN_ALS) (NCT02572479) | University of Jena | 2015-10-01 |
| Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year (NCT02496767) | Cytokinetics | 2015-09-03 |
| Immuno-modulation in Amyotrophic Lateral Sclerosis- a Phase II Study of Safety and Activity of Low Dose Interleukin-2 (NCT02059759) | Centre Hospitalier Universitaire de Nīmes | 2015-09-01 |
| Noninvasive Assessment of Neuronal Damage by MRI Sodium ( 23Na ) in Amyotrophic Lateral Sclerosis (NCT02874209) | Assistance Publique Hopitaux De Marseille | 2015-09-01 |
| Imaging Biomarkers in ALS (NCT02567136) | University of Minnesota | 2015-09-01 |
| SSRIs vs. TCAs for Depression in ALS Patients (NCT02851914) | St. Louis University | 2015-07-21 |
| Relationship Between Neurological Disability and Visual Impairment in Patients With ALS or Friedreich's Ataxia (NCT03285204) | Jose Luis Urcelay Segura | 2015-07-01 |
| Exploratory Study of Biotelemetry in Amyotrophic Lateral Sclerosis (NCT02447952) | GlaxoSmithKline | 2015-06-30 |
| Clinical Trial of Ezogabine (Retigabine) in ALS Subjects (NCT02450552) | Brian Wainger | 2015-06-01 |
| Diaphragmatic Pacer Placement: Anesthetic Management (DP) (NCT02942953) | Institut Guttmann | 2015-06-01 |
| Mesenchymal Stem Cell Injection in Amyotrophic Lateral Sclerosis (NCT02116634) | Alzahra Hospital, Iran | 2015-05-01 |
| Electronic-health Application To Measure Outcomes REmotely Clinical Trial (NCT02418546) | Massachusetts General Hospital | 2015-04-01 |
| Phenotype, Genotype & Biomarkers in ALS and Related Disorders (NCT02327845) | University of Miami | 2015-04-01 |
| Accurate Test of Limb Isometric Strength (ATLIS) in ALS (NCT02374606) | Cedars-Sinai Medical Center | 2015-03-01 |
| Microglial Activation Role In ALS (MARIA) (NCT02405403) | University Hospital, Tours | 2015-03-01 |
| Efficacy, Safety and Tolerability of High Lipid and Calorie Supplementation in Amyotrophic Lateral Sclerosis (NCT02306590) | University of Ulm | 2015-02-01 |
| Study of Predictive Factors of Progression of Motor Neurone Disease (NCT02360891) | University Hospital, Lille | 2015-01-12 |
| An Online Mindfulness Intervention for People With ALS and Their Caregivers (NCT03095989) | Harvard University | 2015-01-01 |
| Effect of Motor Rehabilitation Treatment on Amyotrophic Lateral Sclerosis (ALS) (NCT02306109) | Azienda Unita' Sanitaria Locale Di Modena | 2015-01-01 |
| A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS) (NCT02288091) | Massachusetts General Hospital | 2015-01-01 |
| Quantitative Analysis of Precise Brain Volume in Amyotrophic Lateral Sclerosis (NCT04952025) | Peking University Third Hospital | 2015-01-01 |
| Compassionate Treatment : An Exploratory Clinical Trial to Assess Treatment of Amyotrophic Lateral Sclerosis (NCT02383654) | China Medical University Hospital | 2015-01-01 |
| A follow-on Study to Assess Long-term Safety and Tolerability of i.c.v Administration of sNN0029 in Patients With ALS (NCT02269436) | Newron Sweden AB | 2015-01-01 |
| sCD163 in ALS Patients (NCT02325375) | University of Aarhus | 2014-12-01 |
| Neuromuscular Magnetic Stimulation in ALS Patients (NCT03618966) | University of Roma La Sapienza | 2014-11-01 |
| Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral Sclerosis (NCT02479802) | Instituto Grifols, S.A. | 2014-11-01 |
| ALS Research Collaborative (NCT06885918) | ALS Therapy Development Institute | 2014-09-12 |
| A Safety Study of sNN0029 Administration Via Intracerebroventricular Route to Patients With ALS (NCT01999803) | Newron Sweden AB | 2014-09-01 |
| Intravenous Injection of Adipose Derived Mesenchymal Stem Cell for ALS (NCT02492516) | Royan Institute | 2014-09-01 |
| Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) (NCT02238626) | MediciNova | 2014-09-01 |
| MRI Biomarkers in ALS (NCT02405182) | University of Alberta | 2014-09-01 |
| European Home Mechanical Ventilation Registry (NCT02315339) | ResMed | 2014-08-01 |
| Combination Therapy of Cord Blood and G-CSF for Patients With Brain Injury or Neurodegenerative Disorders (NCT02236065) | MinYoung Kim, M.D. | 2014-08-01 |
| The Ontario Neurodegenerative Disease Research Initiative (NCT04104373) | Ontario Neurodegeneration Disease Research Initiative | 2014-07-07 |
| A Multicenter Phase I/II Clinical Trial to Evaluate Safety of Mesenchymal Stem Cell in Patients With Amyotrophic Sclerosis Lateral (NCT02290886) | Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud | 2014-07-01 |
| Study of miRNA Expression Pattern as Diagnostic and Prognostic Biomarker in Amyotrophic Lateral Sclerosis (NCT01992029) | University Hospital, Bordeaux | 2014-06-17 |
| A New Eye-based Communication Device for ALS Patients (NCT02313402) | Assistance Publique - Hôpitaux de Paris | 2014-06-01 |
| Epidemiology and Genetics of the Amyotrophic Lateral Sclerosis in the French West Indies (NCT03367650) | Centre Hospitalier Universitaire de la Guadeloupe | 2014-05-13 |