| Phase 3 Trial of JMKX001899 Versus Docetaxel in Previously Treated Advanced or Metastatic KRAS G12C-Mutant NSCLC (NCT07242274) | Jemincare | 2025-12-31 |
| Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation (NCT07227844) | Markey Olson | 2025-12-31 |
| Phase II Clinical Study of HRS-9057 Injection in Patients With Heart Failure-induced Fluid Retention (NCT07318103) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2025-12-31 |
| Behavioral Health Evaluation and Intervention Program for Patients Undergoing Craniotomy (NCT05789862) | University of California, San Francisco | 2025-12-31 |
| A Study to Evaluate the Food Effect on RNK08954 in Healthy Participants, and the Mass Balance Study of [14C]RNK08954 in Healthy Adult Male Subjects (NCT07334262) | Ranok Therapeutics (Hangzhou) Co., Ltd. | 2025-12-31 |
| Regulatory Post Marketing Surveillance (rPMS) Study of Rybelsus (Oral Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea (NCT05714683) | Novo Nordisk A/S | 2025-12-31 |
| Intraoral Cryotherapy on Anesthetic Efficacy in Mandibular Incisors (NCT07517367) | Ondokuz Mayıs University | 2025-12-31 |
| Cardiac Perfusion and Metabolism With [11C] Acetate PET/CT is Associated With Hematopoietic System Activation in Acute Decompensated Heart Failure: An Imaging Sub-study (NCT03924102) | University of Alabama at Birmingham | 2025-12-31 |
| Investigation on Suicide Risk Factors of Patients With Mood Disorders (NCT07523490) | Tianjin Anding Hospital | 2025-12-31 |
| A Study to Determine the Metabolism and Excretion of [14C]E2086 in Healthy Male Participants (NCT07308236) | Eisai Inc. | 2025-12-31 |
| LEF1 EXPRESSION IN B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS: A MARKER FOR DIAGNOSIS AND SURVIVAL PREDICTION (NCT07313982) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2025-12-31 |
| Comparison of Conventional and Short Submucosal Tunnel Techniques in Type II Achalasia (NCT07325071) | Asian Institute of Gastroenterology, India | 2025-12-31 |
| The Association Between Primary Aldosteronism and Cognitive Dysfunction (NCT07304674) | Xinjiang Medical University | 2025-12-31 |
| The Effect of Therapeutic Touch on Agitation, Pain, and Cortisol Levels in Intensive Care Patients (NCT07061340) | Firat University | 2025-12-31 |
| Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers (NCT05296005) | Ohio State University Comprehensive Cancer Center | 2025-12-31 |
| Evaluation of Well Being and Patient Reported Outcomes After Robotic Single-port Nipple Sparing Mastectomy and Implant Reconstruction (NCT07236359) | Beaumont Hospital | 2025-12-31 |
| Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer (NCT07366047) | Peking University Cancer Hospital & Institute | 2025-12-31 |
| Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study (NCT07196839) | University of Texas Southwestern Medical Center | 2025-12-31 |
| Study of ZGGS34 in Participants With Advanced Solid Tumors (NCT07258121) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2025-12-31 |
| Neoadjuvant SBRT Followed by Sintilimab Plus Chemotherapy for N3-Positive NSCLC (NCT07309952) | Yang Hong | 2025-12-31 |
| A Study to Evaluate Efficacy and Safety of QLG1218(Daprodustat) in Chinese Hemodialysis (HD)-Dependent Subjects With Anemia Associated With Chronic Kidney Disease (CKD) (NCT07300111) | Qilu Pharmaceutical Co., Ltd. | 2025-12-31 |
| Allo-HSCT Vs. Auto-HSCT for PTCL Patients With PR After First-line Systemic Therapy : A Prospective, Multicenter, Cohort Study-(T-START-PR) (NCT07253129) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2025-12-31 |
| PROMs-guided Perioperative Care in Patients With Complex Care Needs: An Open-label Randomized Controlled Trial (NCT07338188) | University Hospital, Strasbourg, France | 2025-12-31 |
| Assessment of A Novel Emergency Transport Ventilator in Mechanically Ventilated Patients (NCT07198269) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-12-31 |
| Malic Acid Supplementation Combined With Immunotherapy in Patients With Solid Tumors (NCT07325123) | The First Affiliated Hospital of Xinxiang Medical College | 2025-12-31 |
| Sucrosomial Vs Intravenous Iron for Preoperative Anemia (NCT07287371) | University of Rochester | 2025-12-31 |
| Second-line Doublet Chemotherapy (FOLFOX or FOLFIRI) Plus Fruquintinib Versus Doublet Chemotherapy (FOLFOX or FOLFIRI) Plus Bevacizumab in Metastatic Colorectal Cancer (NCT07150403) | Federation Francophone de Cancerologie Digestive | 2025-12-31 |
| A Clinical Study on the Treatment of Wilson Disease With ATP7B mRNA/LNP (DSL101) (NCT07240896) | DSciLab Co., Ltd. | 2025-12-31 |
| The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-HF) (NCT03180450) | Sclnow Biotechnology Co., Ltd. | 2025-12-31 |
| Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab. (NCT07330245) | AstraZeneca | 2025-12-31 |
| Clinical Trial to Evaluate the Efficacy and Safety of TVAX-008 Injection in the Treatment of Chronic Hepatitis B (NCT07282249) | Grand Theravac Life Sciences (Nanjing) Co., Ltd. | 2025-12-31 |
| Ritlecitinib (PF-06651600) in Participants With Chronic Spontaneous Urticaria (NCT06795373) | Ahuva D Cices | 2025-12-31 |
| Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma (NCT05636085) | Mainz Biomed | 2025-12-31 |
| Comparing Advanced Hemostasis and Ultrasound-Guided Puncture to Conventional Approaches in Distal Radial Access (NCT06835829) | Associazione per lo Studio delle Malattie Cardiovascolari Cardiva ONLUS | 2025-12-31 |
| Anxiety During Caries Removal Using Chemo-mechanical Versus Conventional Methods (NCT07344415) | Cairo University | 2025-12-31 |
| A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer (NCT07221357) | Bristol-Myers Squibb | 2025-12-31 |
| Acarbose in Combination With Standard Therapy in Metastatic Renal Cell Carcinoma (RCC) (NCT05487859) | University of Alabama at Birmingham | 2025-12-31 |
| Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients (NCT07693972) | Sara M Almshhadany | 2025-12-31 |
| Robotic Gastrectomy With 5th Arm (NCT07310888) | Chinese University of Hong Kong | 2025-12-31 |
| Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight (NCT07363616) | The Miriam Hospital | 2025-12-31 |
| Clinical Study of LV009 Injection in the Treatment of Recurrent/Refractory CD19 Positive Blood Tumors (NCT07330895) | The First Affiliated Hospital with Nanjing Medical University | 2025-12-31 |
| Efficacy and Safety of Minocycline in the Treatment of Intracerebral Hemorrhage (NCT07305896) | The First Hospital of Jilin University | 2025-12-31 |
| MicroRNA and MicroRNA Inhibitors Socket Study, Pilot Clinical Trial (NCT02579187) | Gustavo Avila-Ortiz DDS, MS, PhD | 2025-12-31 |
| Ultrasound Guided Bilateral Erector Spinae Block as Analgesia for Adolescent Idiopathic Scoliosis Correction (NCT04336046) | Tanta University | 2025-12-31 |
| Cardiovascular Risk Factors in Middle Eastern Patients With Stroke (NCT07298668) | Jordan Collaborating Cardiology Group | 2025-12-31 |
| Predictive Value of Minimal Residual Disease for Postoperative Recurrence and Adjuvant PD-1 Inhibitor in HCC (NCT07350824) | Tongji Hospital | 2025-12-31 |
| Clinical Study on the Safety and Efficacy of a New Magnetic Navigation Radiofrequency Ablation Catheter for Rapid Arrhythmia (NCT07067372) | Shanghai MicroPort EP MedTech Co., Ltd. | 2025-12-31 |
| Handgrip Strength Increases the Pressure in the Portal and Left Gastric Veins in Cirrhotic Patients (NCT07289698) | Shanxi Provincial People's Hospital | 2025-12-31 |
| Coenzyme Q10 in Pediatric Community-Acquired Pneumonia (NCT07317440) | Tanta University | 2025-12-31 |
| Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants (NCT07223671) | Bristol-Myers Squibb | 2025-12-31 |
| TACE Combined With Tislelizumab, Lenvatinib, and Carvedilol for Unresectable HCC With Cirrhotic Portal Hypertension (NCT07350070) | Tongji Hospital | 2025-12-31 |
| The STTAR-US Study: A Pivotal Study of Transcatheter Tricuspid Annular Repair in the US (NCT06700239) | Micro Interventional Devices | 2025-12-31 |
| Physical Activity and Gut Microbiota in Children (PA-Microbiome Kids) (NCT07310654) | Aiyoudong Children and Youth Sports Health Research Institute | 2025-12-31 |
| Real-world Evaluation of the Effectiveness of Immunoglobulin-Histamine Complex, IHC (Histoglob) in Chronic Urticaria (NCT07680413) | Bharat Serums and Vaccines Limited | 2025-12-31 |
| An Umbrella Study of Recurrent, Extensive Stage Small Cell Lung Cancer Based on Molecular Typing (NCT07141771) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-12-31 |
| The Effect of PBM on the Electrical Activity of the Brain in Stroke Patients (NCT07323823) | Pusan National University Yangsan Hospital | 2025-12-31 |
| Fruquintinib Combined With Trifluridine/Tipiracil Versus Bevacizumab Combined With Trifluridine/Tipiracil for Advanced Metastatic Colorectal Cancer (NCT07286695) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-12-31 |
| A Clinical Study of Evaluating Myocardial Viability in Ischemic Heart Disease with Integrated 18F-FDG PET/MR (NCT06712862) | Shanghai East Hospital | 2025-12-31 |
| An Exploratory Study of Lurbinectedin With Radiotherapy in SCLC With Single-lesion Progression After First Course Treatment (NCT06501976) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-12-31 |
| A Phase II Study to Evaluate the Efficacy and Safety of Anti-HER2 Triple-targeted Drugs Combined With CDK4/6 Inhibitors in Neoadjuvant Therapy for ER-positive HER2-positive Breast Cancer Patients. (NCT07290166) | Fudan University | 2025-12-31 |
| A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients (NCT03541486) | Joseph J. Cullen, MD, FACS | 2025-12-31 |
| A Study of B2065 in Patients With Acute Ischemic Stroke (NCT07371624) | Tasly Pharmaceutical Group Co., Ltd | 2025-12-31 |
| Evaluate the Safety and Immunogenicity of the MVA-SIBP Vaccine in the Democratic Republic of the Congo (NCT07253675) | Shanghai Institute Of Biological Products | 2025-12-31 |
| Phase II Randomized, Open-label, Multicenter Clinical Study Evaluating the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of SHR-2173 Injection in Patients With Primary Membranous Nephropathy (NCT07289763) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2025-12-31 |
| The Effect of Sodium Bicarbonate (Nephrotrans®) on Calcification Propensity of Serum in Kidney Transplant Recipients (NCT03301558) | Prim. Priv. Doz. Dr. Daniel Cejka | 2025-12-31 |
| A First-in-human, Single-ascending-dose Study of IBI3033 in Healthy Participants (NCT07311226) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-12-31 |
| Safety and Efficacy of Adipose-Derived Regenerative Cells (ADRCs) for Improving Hand Dysfunction in Systemic Sclerosis (NCT07360808) | Cytori Therapeutics | 2025-12-31 |
| Efficacy and Safety of Extended-Dose Interval Immunotherapy Versus Standard-Dose Interval Immunotherapy for Advanced Triple-Negative Breast Cancer (NCT07401537) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2025-12-31 |
| A Multicenter Real-World Study on TKI Therapy After Progression on First-Line TKI/IO Therapy or TKI/IO Therapy After Progression on First-Line TKI in Chinese Patients With Metastatic Renal Cell Carcinoma (mRCC) (NCT07324876) | Tianjin Medical University Cancer Institute and Hospital | 2025-12-31 |
| XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation (NCT05275374) | Xynomic Pharmaceuticals, Inc. | 2025-12-31 |
| Postoperative Wounds With Delayed Healing Risk of Clinical Trial Registration (NCT06272097) | Danni Feng | 2025-12-31 |
| Clinical Study on the Safety and Efficacy of CD20/CD19 Cell Injection in the Treatment of Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NCT07345741) | Donghua Zhang | 2025-12-31 |
| Hologram Burn Dressing on Pain, Anxiety, Fear, Patient Satisfaction, and Physiological Parameters (NCT07244653) | Gamze BULUT | 2025-12-31 |
| Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma (NCT07713901) | Novo Nordisk A/S | 2025-12-31 |
| Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study (NCT07203144) | First Affiliated Hospital of Chongqing Medical University | 2025-12-31 |
| Phase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma (NCT07276386) | H. Lee Moffitt Cancer Center and Research Institute | 2025-12-31 |
| ZSDT for the Treatment of R/R Mantle Cell Lymphoma After BTK Inhibitor Failure: a Multi-center Prospective Clinical Trial (NCT07264894) | Zhengzhou University | 2025-12-31 |
| Novel Bispecific AbTCR (Anti-CD19/CD22)-T Cells in Relapsed or Refractory B-cell Lymphoma (NCT07168291) | First Affiliated Hospital Xi'an Jiaotong University | 2025-12-31 |
| LED Red Light in Modulating Choroidal Microcirculation to Retard Retinal Atrophy in Pathological Myopia (NCT07312214) | Shanghai Eye Disease Prevention and Treatment Center | 2025-12-31 |
| Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function. (NCT07329751) | Fujian University of Traditional Chinese Medicine | 2025-12-31 |
| A Study to Evaluate Efficacy and Safety of IBI356 in Participants With Moderate to Severe Atopic Dermatitis (NCT07330934) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-12-31 |
| Observ Prosp Study of Acalabrutinib in CLL Therapy in Real Clinical Practice in Belarus (NCT07288515) | AstraZeneca | 2025-12-31 |
| Precision Diabetes Management: Integrated East-West Approach (NCT07307040) | Peking Union Medical College Hospital | 2025-12-31 |
| Safety of Combined Intravenous Antibiotic and Bacteriophage Therapy in Adults With Cystic Fibrosis and Antibiotic-Resistant Lung Infections (NCT07280598) | University of California, San Diego | 2025-12-31 |
| Effect of Therapeutic Touch on Perceived Stress and Comfort Levels in Hemodialysis Patients (NCT07061353) | Firat University | 2025-12-31 |
| The Effect of Bruxism on Balance (NCT07308145) | Istinye University | 2025-12-31 |
| To Evaluate the Safety and Efficacy of GS1168 Injection in Adult Phenylketonuria (NCT07318909) | Gritgen Therapeutics Co., Ltd. | 2025-12-31 |
| Prevelance and Severity of Gerd in Patients With Metabolic Syndrome and How Both Affect Together ( Relationship) (NCT07302022) | Assiut University | 2025-12-30 |
| Infrasensor for Early Detection of a High-grade Obstructive NSTE-ACS (NCT07464704) | Remote Cardiac Enablement | 2025-12-30 |
| A Study Evaluating the Efficacy and Safety of ABP1011T Tablets in Patients With Advanced Solid Tumors (NCT07321574) | Shanghai AB PharmaTech Ltd. | 2025-12-30 |
| A Randomized, Open-label, Double-cohort Study of Fluzoparib Combined With Famitinib Malate or SHR-1701 for Neoadjuvant Therapy in Patients With Advanced Ovarian Cancer (NCT07355010) | Qinglei Gao | 2025-12-30 |
| A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors (NCT07361562) | Cogent Biosciences, Inc. | 2025-12-30 |
| Evaluation of a Neuropsychological Tool to Assess Temporal Processing Abilities in Alzheimer's Disease (NCT07341009) | University Hospital, Caen | 2025-12-30 |
| Comparison of the Efficacy and Safety of Fixed-rate Basal Infusion Mode and Time-programmed Decremental Background Infusion Mode of Intravenous PCA Following Mixed Surgery (NCT07375121) | Beijing Tiantan Hospital | 2025-12-30 |
| Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia (NCT06735690) | City of Hope Medical Center | 2025-12-30 |
| Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial) (NCT07295223) | Instituto Mexicano del Seguro Social | 2025-12-30 |
| Randomized Controlled Study of Dragonfly System for Functional Mitral Regurgitation (NCT07243158) | Hangzhou Valgen Medtech Co., Ltd | 2025-12-30 |
| The Benefits of Wearable AI in Post-Discharge Management of AMI Patients (NCT07288229) | RenJi Hospital | 2025-12-30 |
| Feasibility of a Habit-Based Intervention to Reduce Sedentary Behaviour in Cancer Survivors (NCT07694479) | University of Toronto | 2025-12-30 |
| Fluid Responsiveness With Passive Leg Raising in Patients Undergoing Coronary Artery Bypass Surgery (NCT07245485) | Ankara City Hospital Bilkent | 2025-12-30 |