| This Study Aims to Compare the Efficacy and Safety of Lumateperone and Cariprazine in Patients With Bipolar I Depression Using Montgomery-Åsberg Depression Rating Scale (MADRS) and Clinical Global Impression Bipolar Severity Scale (CGI-BP-S) and Recording Treatment Emergent Adverse Effects. (NCT07676669) | Watim Medical & Dental College | 2026-12-01 |
| Understanding Treatment Outcomes and Immunologic Mechanisms in Altuviiio Immune Tolerance Induction (NCT07158606) | Versiti Blood Health | 2026-12-01 |
| Medial Prefrontal Cortex Brain Magnetic Stimulation in Autism (NCT07770451) | National Taiwan University Hospital | 2026-12-01 |
| AI-Based Oxytocin-Stimulated Smart Lactation Support Vest (NCT07765992) | Selcuk University | 2026-12-01 |
| Trial of a Nurse-Led Firearm Safety Intervention in the Pediatric Inpatient Setting (NCT07501247) | University of Pennsylvania | 2026-12-01 |
| Effect on Bronchodilation Response and Ventilation Heterogeneity of Different Inhalation Volumes in COPD (NCT05381415) | University of Milan | 2026-12-01 |
| Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients (NCT07234526) | Assiut University | 2026-12-01 |
| XVIE to Treat Androgenetic Alopecia (AGA) (NCT07482423) | Restore Biologics Holdings, Inc. dba Xtressé | 2026-12-01 |
| A Study to Evaluate the Efficacy and Safety of ENERGI-F705 Tablets for Parkinson's Disease (NCT07647614) | Energenesis Biomedical Co., Ltd. | 2026-12-01 |
| The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients (NCT07415577) | University Children's Hospital, Zurich | 2026-12-01 |
| Daily Iron vs Every-other-day Iron for Pediatric Patients With IDA (NCT06550362) | Loma Linda University | 2026-12-01 |
| Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator (NCT06643052) | Hillel Yaffe Medical Center | 2026-12-01 |
| Multimodal Conservative Intervention Versus Surgery for Chronic Refractory Plantar Fasciopathy (NCT07654660) | Universidad Europea de Valencia | 2026-12-01 |
| Image-Guided Herniorrhaphy Study (NCT07267494) | University of California, Davis | 2026-12-01 |
| Digital Patient-Reported Assessment in Older Adults With Acute Leukemia (NCT07597590) | Fundación para la Investigación Biosanitaria del Principado de Asturias | 2026-12-01 |
| PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma (NCT06448286) | Jonsson Comprehensive Cancer Center | 2026-12-01 |
| Individualized Energy Expenditure Assessment in Critically Ill Patients (NCT07547865) | Assiut University | 2026-12-01 |
| Use of a Silicone Sensor to Protect Fragile Neonatal Skin in Moderately Preterm Infants Needing Continuous Monitoring (NCT07753863) | Paolo Manzoni Study Group | 2026-12-01 |
| REducing pSychological diSTress To Optimize Recovery of Elderly ICU Survivors and Caregivers (RESTORE-ICU) (NCT06867367) | Beth Israel Deaconess Medical Center | 2026-12-01 |
| Evaluating a Digital Toolkit for IPV (NCT07600307) | Medical University of South Carolina | 2026-12-01 |
| Shaping a Community-based Pathway to Improve TB Surveillance Among African and Hindustan Immigrants Experiencing Vulnerabilities (NCT07687121) | Universidade Nova de Lisboa | 2026-12-01 |
| Geriatrics in the Intensive Care Unit (NCT07001410) | Hospital Departamental de Villavicencio | 2026-12-01 |
| Electrophysiologic Mechanisms of Ketamine Antidepressant Response (NCT07768618) | Emory University | 2026-12-01 |
| Chronic Fatigue in Multiple Sclerosis: MS Copilot Boost Solution Compared to Standard Care (NCT06386133) | Ad scientiam | 2026-12-01 |
| A Phase I Evaluation of the Safety and Tolerability of Pirfenidone in Idiopathic Subglottic Stenosis (NCT07654517) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2026-12-01 |
| Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy (NCT07086183) | Mayo Clinic | 2026-12-01 |
| Autologous Hematopoietic Stem Cell Transplantation for Refractory Multiple Sclerosis (NCT06228781) | Tianjin Medical University General Hospital | 2026-12-01 |
| Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness (NCT07291778) | University of Alabama at Birmingham | 2026-12-01 |
| Enhancing Amoxicillin Pharmacokinetics and Pharmacodynamics Parameters With Probenecid in Bone and Joint Infections (NCT07764302) | Assistance Publique - Hôpitaux de Paris | 2026-12-01 |
| Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis (NCT04768777) | University of Alabama at Birmingham | 2026-12-01 |
| Treatment of Chronic Thyroid Eye Disease With MHB018A (NCT07622121) | Minghui Pharmaceutical (Hangzhou) Ltd | 2026-12-01 |
| Therapeutic Drug Monitoring-baSed adalimuMab De-escalatiOn in nOn-infecTious cHronic Uveitis (NCT06390436) | Centre Hospitalier Universitaire de Saint Etienne | 2026-12-01 |
| Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV (NCT06233331) | Emory University | 2026-12-01 |
| Tricaprilin Phase 3 ALTER-AD (Alternative-Alzheimer Disease) Study (NCT05809908) | Cerecin | 2026-12-01 |
| Catalan Translation and Psychometric Validation of the QuickDASH (NCT07750028) | Corporacion Parc Tauli | 2026-12-01 |
| Testing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery (CalmiFy II) (NCT07088237) | Washington State University | 2026-12-01 |
| Etenta-Isa-VRd in Newly Diagnosed High-Risk Multiple Myeloma (NCT07600151) | Universitätsklinikum Hamburg-Eppendorf | 2026-12-01 |
| Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy (NCT07607067) | Hospital de Mataró | 2026-12-01 |
| Facilitating Transition to Recommended PTSD Treatment (NCT05165940) | VA Office of Research and Development | 2026-12-01 |
| Shape-sensing Versus Electromagnetic Robotic Bronchoscopy for Evaluation of PulmoNary LEsions (NCT07411989) | The Cleveland Clinic | 2026-12-01 |
| Clinical Evaluation of a Tubal Selective Delivery System (NCT05775913) | Oregon Health and Science University | 2026-12-01 |
| Mechanistic Clinical Trial of PCSK9 Inhibition for AAA (NCT06081153) | University of Pennsylvania | 2026-12-01 |
| 3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain (NCT05265052) | 3D Medicines | 2026-12-01 |
| Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children (NCT06955338) | Ege University | 2026-12-01 |
| Data-Driven Phenotyping in Heart Failure With Preserved Ejection Fraction (NCT07429396) | Instituto Politécnico de Leiria | 2026-12-01 |
| Efficacy and Safety of a Repurposed Drug Added to the Combination of Len Plus Pem in Advanced Endometrial Cancer (NCT05077215) | Evergreen Therapeutics, Inc. | 2026-12-01 |
| Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic Syndrome (NCT07770282) | All India Institute of Medical Sciences, Bhubaneswar | 2026-12-01 |
| Minocycline In Neurocognitive Outcomes - Sickle Cell Disease (NCT05605366) | University of Cincinnati | 2026-12-01 |
| Wearable Data for Personalized Prognostication in Cancer: A Registry Protocol (NCT07691008) | City of Hope Medical Center | 2026-12-01 |
| A Study About the Diagnosis and Management of Hereditary Angioedema (HAE) in Egypt (NCT07218393) | Takeda | 2026-12-01 |
| Using Apollo Neuro in Autistic Children With Self-Injurious Behavior (NCT07648420) | Virginia Commonwealth University | 2026-12-01 |
| ZR001 Chemogenetics Gene Therapy Study in Patients With Parkinson's Disease (NCT07718659) | Qianfoshan Hospital | 2026-12-01 |
| Study on Influencing Factors of Skin Complications Related to Insulin Injection in Children With Type 1 Diabetes Mellitus (NCT07615803) | The Children's Hospital of Zhejiang University School of Medicine | 2026-12-01 |
| Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C Trial (NCT07206589) | Mayo Clinic | 2026-12-01 |
| A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection (NCT06987318) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-12-01 |
| Intracerebroventricular Tralesinidase Alfa in Participants With MPS IIIB (Sanfilippo Syndrome Type B) (NCT07579910) | Spruce Biosciences | 2026-12-01 |
| Evaluate the Safety and Tolerability of CE211NS21 in Patients With AQP4-IgG-positive NMOSD Relapse (NCT07595965) | Corestemchemon, Inc. | 2026-12-01 |
| Targeted LSAM-Cisplatin Infusion in Gliomas, Evaluation of Response (NCT07767110) | NanOlogy, LLC | 2026-12-01 |
| Low Intensity Focused Ultrasound for Parkinson's Disease (NCT06763692) | Ali Rezai | 2026-12-01 |
| Retrospective Analysis of CPET and Cognitive Tests of Healthy Individuals, Treated With 60 Treatment of HBOT (NCT07596641) | Assaf-Harofeh Medical Center | 2026-12-01 |
| Hallux Valgus Correction Using the Metal Screw or the Human Allogeneic Cortical Bone Screw (Shark Screw). (NCT06262204) | Orthopedic Hospital Vienna Speising | 2026-12-01 |
| VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway (NCT06320951) | University of Alabama at Birmingham | 2026-12-01 |
| Testing an Intervention for College Students With Food Insecurity and Binge Eating (NCT07521072) | Virginia Polytechnic Institute and State University | 2026-12-01 |
| Longitudinal PET Imaging of Antipsychotic Binding to the Dopamine-3 Receptor in Schizophrenia (NCT07715253) | New York State Psychiatric Institute | 2026-12-01 |
| Recurrent or Persistent Device Related Thrombus After Left Atrial Appendage Occlusion: The RE-DRT Study (NCT06177704) | Institut universitaire de cardiologie et de pneumologie de Québec, University Laval | 2026-12-01 |
| The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD (NCT04231760) | University of Alberta | 2026-12-01 |
| Predictors of Extubation Failure in Ventilated Neonates (NCT07764575) | Assiut University | 2026-12-01 |
| Elucidating the Central Mechanisms of Action for Green Light Therapy in Managing Chronic Pain (NCT05569486) | University of Arizona | 2026-12-01 |
| Revumenib in Patients With Myelofibrosis (NCT07734077) | John Mascarenhas | 2026-12-01 |
| Crisis Interventions for Pediatric Providers - Autism Version (NCT07508436) | Children's Hospital Los Angeles | 2026-12-01 |
| Menin-Inhibitor Targeted Maintenance in AML (NCT07563010) | Center for International Blood and Marrow Transplant Research | 2026-12-01 |
| Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone (NCT07225972) | New York Medical College | 2026-12-01 |
| Phenotyping Acute Non-Severe Anemia in the Emergency Department (NCT07761104) | Hospices Civils de Lyon | 2026-12-01 |
| A Phase 1b/2a Study of Velinotamig in Adults With Relapsed/Refractory ITP and wAIHA (NCT07738822) | Cullinan Therapeutics Inc. | 2026-12-01 |
| To Establish Whether Dapagliflozin and Spironolactone in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement, Result in Better Left Ventricular Mass Regression, Myocardial Health and Patient Reported Outcomes (NCT07539259) | University College, London | 2026-12-01 |
| Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial (NCT06170281) | Mayo Clinic | 2026-12-01 |
| Erlotinib for Hepatocellular Carcinoma Chemoprevention (NCT04172779) | University of Texas Southwestern Medical Center | 2026-12-01 |
| Supportive Treatment With Enhanced Post-Incarceration Services (NCT07744841) | Catherine E. Paquette, PhD | 2026-12-01 |
| Retreat-Based Program for Violence-Exposed Women Veterans (NCT07738445) | VA Office of Research and Development | 2026-12-01 |
| Mercaptopurine for the Treatment of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC), Uterine/Cutaneous Leiomyomas, and Kidney Cancer (NCT07716735) | Jonsson Comprehensive Cancer Center | 2026-12-01 |
| Improving Functioning Among Aging Women Veterans (NCT06580470) | VA Office of Research and Development | 2026-12-01 |
| 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome (NCT07290530) | Nacuity Pharmaceuticals, Inc. | 2026-12-01 |
| Augmentation Cystoplasty Using an Autologous Neo-Bladder Construct (NCT05054790) | Wake Forest University Health Sciences | 2026-12-01 |
| BC-101 in Treatment of Nasolabial Fold Wrinkles (NCT05162326) | Bright Cell, Inc. | 2026-12-01 |
| Pilot Trial of an Emotion Regulation and Executive Functioning Intervention for Self-Injurious Thoughts and Behaviors (SITBs) in Children (NCT07281365) | University of Colorado, Denver | 2026-12-01 |
| Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers (NCT05331209) | Shaare Zedek Medical Center | 2026-12-01 |
| NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI (NCT05635851) | Simon Fraser University | 2026-12-01 |
| Crisis Response Planning in Military Personnel With Mild Traumatic Brain Injury (NCT07327567) | The University of Texas Health Science Center at San Antonio | 2026-12-01 |
| Continuous Erector Spinae Block for Analgesia Following Lumbar Decompression (NCT06987409) | Nova Scotia Health Authority | 2026-12-01 |
| Splintless Versus Conventional Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea (NCT07598461) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2026-12-01 |
| The BRIGHT Study (Device Name: HALO System) (NCT07745998) | Indigo Diabetes NV | 2026-12-01 |
| Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer (NCT07667335) | Fred Hutchinson Cancer Center | 2026-12-01 |
| A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation (NCT07752875) | LG Chem | 2026-12-01 |
| Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings (NCT07755137) | Children's Hospital Los Angeles | 2026-12-01 |
| Accelerated iTBS for Depression and Suicidality (NCT04441008) | University of Iowa | 2026-12-01 |
| Prospective Twin Pregnancy Cohort at Montpellier University Hospital (NCT07408973) | University Hospital, Montpellier | 2026-12-01 |
| Feasibility and Acceptability of Mobile Mental Health App for SZ and SZA (NCT06474325) | University of Pittsburgh | 2026-12-01 |
| Improv Music Therapy for Older Adults (NCT07419022) | University of California, San Francisco | 2026-12-01 |
| EUS-DFI in Solid Pancreatic Lesions (NCT07763561) | Julio Iglesias García | 2026-12-01 |
| Study of Zanubrutinib in Older Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (NCT07739459) | The Lymphoma Academic Research Organisation | 2026-12-01 |