| RESTAGE (REpurposing STAtins to Improve Outcomes in GastroEsophageal Cancer) Trial (NCT07625930) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2027-01-01 |
| Chrono-Fasting in Overweight and Obese Adolescents (NCT07759414) | University of Thessaly | 2027-01-01 |
| Sequential Immune Modulation and Antigen-Specific Tolerance Induction for Disease Modification in Recent-Onset Type 1 Diabetes (NCT07610213) | Abdullah Kars | 2027-01-01 |
| Personalizing Mental Health Treatment for Youth and Families (NCT07425366) | University of Oregon | 2027-01-01 |
| Intraoperative Placement of Vancomycin-impregnated Calcium Sulfate Beads Conjugated With Analgesics to Improve Spine Surgery Outcomes (NCT07201987) | Ganesh M. Shankar | 2027-01-01 |
| E-cigarette Social Media Marketing and Its Perceptions by Youth (NCT07694739) | University of Southern California | 2027-01-01 |
| Evaluation of the Variation in Quality of Life During Medical Transition for Transgender People. (NCT05273112) | University Hospital, Lille | 2027-01-01 |
| Investigation of Chemical Stability and Sterility of Morphine in Intrathecal Pumps for Long-Term Pain Management (NCT07641608) | Meir Medical Center | 2027-01-01 |
| Multimodal Therapy for Somatosensory Tinnitus (NCT07468318) | Charles University, Czech Republic | 2027-01-01 |
| Safety and Immunogenicity Study of the DuoChol Oral Cholera Vaccine in Healthy Participants (NCT07270796) | International Vaccine Institute | 2027-01-01 |
| Nursing Intervention for Adaptation After Myocardial Revascularization (NCT07576569) | Universidad de la Sabana | 2027-01-01 |
| Trial to Evaluate an Educational Video Series for Women in Breast Cancer Treatment (NCT07434817) | University of Colorado, Denver | 2027-01-01 |
| Effect of Behavioral Intervention (Baduanjin Alone or Laughter Exercise Plus Artificial Tears) Versus Artificial Tear on Dry Eye Disease: a Randomised Controlled Trial (NCT07524725) | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2027-01-01 |
| Clinical Efficacy of Exoskeleton Assistance for Individuals Post-Stroke (NCT06064604) | Georgia Institute of Technology | 2027-01-01 |
| An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia Nervosa (NCT06518941) | New York State Psychiatric Institute | 2027-01-01 |
| Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents (NCT07301541) | University of Aarhus | 2027-01-01 |
| The Disrupted Bodily Self of Patients (NCT04957576) | University of Geneva, Switzerland | 2027-01-01 |
| The FamilyStrong Pilot Randomized Trial (NCT07761988) | University of Alabama at Birmingham | 2027-01-01 |
| Acute Cholecystitis Biliary Complications - ICG (NCT07481760) | Hospital del Mar | 2027-01-01 |
| Leveraging Behavioral Economics to Understand and Improve Financial Decision Making Among Vulnerable Older Adults (NCT07682740) | The University of Texas Health Science Center, Houston | 2027-01-01 |
| Efficacy of "DBT-LIVE", an Identity Skills Training Program, for Borderline Personality Disorder. (NCT07684872) | Universidad Europea de Valencia | 2027-01-01 |
| Beat-to-beat Evaluation of Atrial Pacing to Test Fluid Responsiveness (NCT07730242) | Maastricht University Medical Center | 2027-01-01 |
| Magnetic Sentinel Lymph Node Mapping in Gastric Cancer (NCT05038098) | M.D. Anderson Cancer Center | 2026-12-31 |
| PHIL™ Middle Meningeal Artery Embolization for First-Line Treatment of Chronic Subdural Hematoma IDE Trial (NCT07576998) | Microvention-Terumo, Inc. | 2026-12-31 |
| A Phase 2 Trial Of The Combination Of Zanubrutinib, Sonrotoclax, And Obinutuzumab For Patients With Treatment-Naïve Chronic Lymphocytic Leukemia (NCT07674810) | M.D. Anderson Cancer Center | 2026-12-31 |
| Clinical Study on the Safety and Efficacy of CD7-Targeted Chimeric Antigen Receptor (CAR) Gene-Modified T Cells for the Treatment of CD7-Positive Hematological Malignancies (NCT07345780) | Donghua Zhang | 2026-12-31 |
| Safety and Preliminary Efficacy of HN2302 in Patients With Autoimmune Diseases (NCT07523282) | Shenzhen MagicRNA Biotechnology Co., Ltd | 2026-12-31 |
| Study Of KITE-753 in R/R B-Cell ALL (NCT07674823) | M.D. Anderson Cancer Center | 2026-12-31 |
| Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia (NCT03378414) | Sclnow Biotechnology Co., Ltd. | 2026-12-31 |
| De-implementing PreOp Urine Testing (NCT07411209) | VA Office of Research and Development | 2026-12-31 |
| Neural, Cognitive, and Biomechanical Determinants of Falls in Older Adults (NCT07739056) | University of Sharjah | 2026-12-31 |
| The Effect of Huperzine A Injection on Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage: a Pilot Study (NCT05560373) | Wanbangde Pharmaceutical Group Co., LTD | 2026-12-31 |
| Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures (NCT07522567) | The Third Affiliated hospital of Zhejiang Chinese Medical University | 2026-12-31 |
| Phase 1 Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cell In Patients With Oral Premalignant Lesions (NCT07631013) | M.D. Anderson Cancer Center | 2026-12-31 |
| Epcoritamab Plus Venetoclax Plus Ibrutinib in Patients With Chronic Lymphocytic Leukemia With TP53 Alterations (NCT07738887) | The Lymphoma Academic Research Organisation | 2026-12-31 |
| Venlafaxine Combined With Education and Behavioral Intervention for Bladder Pain Syndrome (NCT07698626) | Beijing Tiantan Hospital | 2026-12-31 |
| An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health (NCT05477953) | Bayer | 2026-12-31 |
| Efficacy and Safety of Pregabalin Combined With Educational and Behavioral Intervention for Bladder Pain Syndrome/Interstitial Cystitis (NCT07752134) | Beijing Tiantan Hospital | 2026-12-31 |
| Antibody-based PET Imaging and Treatment Response in Breast Cancer Treated With an Antibody-drug Conjugate. (NCT07294430) | UNICANCER | 2026-12-31 |
| Cryotherapy vs Lidocaine Spray for Oral Mucositis (NCT07727031) | Hanady Jabbar Mahmood | 2026-12-31 |
| A Single-center, Randomized, Open-label, Parallel-design Clinical Study to Evaluate the Pharmacokinetic Effects of Itraconazole, Fluconazole or Efavirenz on a Single Dose of Clifutinib in Healthy Participants (NCT07341672) | Sunshine Lake Pharma Co., Ltd. | 2026-12-31 |
| Wearable Device Tracked Recovery From Autologous Breast Reconstructive Surgery (NCT07631026) | M.D. Anderson Cancer Center | 2026-12-31 |
| Assessment of Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments (NCT07396922) | Motion Informatics LTD | 2026-12-30 |
| Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block After Laparoscopic Sleeve Gastrectomy (NCT07591129) | Antalya City Hospital | 2026-12-30 |
| 3D Printed Occlusal Splints for Intraoperative Use (NCT07079111) | Johns Hopkins University | 2026-12-30 |
| Apremilast and Adalimumab in Psoriatic Arthritis Patients (NCT07398651) | Tanta University | 2026-12-30 |
| Efficacy of Autologous Adipose Derived Stromal Vascular Fraction for Musculoskeletal Conditions (NCT06000670) | Dubai Health Authority | 2026-12-30 |
| Pulmonary Artery Denervation for Heart Failure With Preserved Left Ventricular Ejection Fraction (NCT07331220) | Nanjing First Hospital, Nanjing Medical University | 2026-12-30 |
| Comparing IVF/ICSI Cycle Outcomes of Post Ovulation Ovarian Stimulation Protocol With Elonva Without GnRH Antagonist to Follicular Phase Day 2 Stimulation Fixed Day 5 Antagonist Protocol (NCT06879002) | ART Fertility Clinics LLC | 2026-12-30 |
| Lead Exposure and Multiple Sclerosis (NCT07423312) | Assiut University | 2026-12-30 |
| Comparing Standard Platelet-Rich Plasma and Light-Enhanced Platelet-Rich Plasma for Treating Hair Loss in Androgenetic Alopecia: A Randomized Controlled Trial (NCT07739147) | Kimberly Meathrel | 2026-12-30 |
| Computerized Decision Support to Prevent Stroke in Atrial Fibrillation (NCT06355986) | Brigham and Women's Hospital | 2026-12-30 |
| Adaptive Digital Exercise Rehabilitation for Children After CHD Surgery (NCT07574463) | The Children's Hospital of Zhejiang University School of Medicine | 2026-12-30 |
| The Effect of Acupressure on Symptoms in Elderly Adults With Painful Diabetic Neuropathy (NCT07392619) | Nigde Omer Halisdemir University | 2026-12-30 |
| PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF (NCT07349979) | Nanjing First Hospital, Nanjing Medical University | 2026-12-30 |
| Study of ISM5939 in Patients With Advanced and/or Metastatic Solid Tumors (NCT06724042) | InSilico Medicine Hong Kong Limited | 2026-12-30 |
| Is the Diurnal Variation in Circulating Levels of Cortisol Reflected in Follicular Fluid of Preovulatory Follicles Close to Ovulation? (NCT06877429) | ART Fertility Clinics LLC | 2026-12-30 |
| This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcting Early-onset Vitamin B12 Deficiency in Adult Patients Using Proton Pump Inhibitors (PPIs). The Primary Outcome is the Change in Serum Vitamin B12 Levels Over a 6-week (NCT06966856) | Tanta University | 2026-12-30 |
| Respiratory Muscle Training in Patients Undergoing Lung Cancer Surgery (NCT07499986) | Saglik Bilimleri Universitesi | 2026-12-30 |
| Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma (NCT07164469) | M.D. Anderson Cancer Center | 2026-12-28 |
| Group-based Comprehensive Lifestyle Program for Women With Metastatic Breast Cancer (NCT07179809) | M.D. Anderson Cancer Center | 2026-12-28 |
| Study to Understand Relationship Between Gut Health and Toxicities of Hormonal Breast Cancer Treatment (NCT07553234) | University of Chicago | 2026-12-27 |
| Clinical Efficacy of Adebrelimab With or Without Apatinib Mesilate and SOX Neoadjuvant Therapy in Locally Advanced Gastric Cancer (NCT07314203) | Fujian Medical University | 2026-12-25 |
| Study of Efficacy and Safety of FRSW107 in Pediatric Patients With Severe Hemophilia A (NCT06136507) | Hangzhou Gensciences Biopharmaceutical Co., Ltd. | 2026-12-25 |
| Probiotic Supplementation During Cytotoxic Chemotherapy for Solid Tumor Malignancies (NCT06772090) | Masonic Cancer Center, University of Minnesota | 2026-12-25 |
| Circadian-Optimized Light Therapy for the Treatment of Patients With Advanced Melanoma Receiving Tumor-Infiltrating Lymphocyte Therapy (NCT07628894) | City of Hope Medical Center | 2026-12-23 |
| Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis (NCT07682623) | Mansoura University | 2026-12-22 |
| Golcadomide in Combination With Rituximab for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma (NCT07578077) | City of Hope Medical Center | 2026-12-21 |
| Effect of Melatonin on Left Ventricular Reverse Remodeling and Inflammation in Peripartum Cardiomyopathy (NCT07334197) | Tanta University | 2026-12-20 |
| Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (NCT07582159) | City of Hope Medical Center | 2026-12-19 |
| Biology Guided Therapy Recommendations for Treatment Determination of Hormone Receptor-Positive Advanced, Unresectable or Metastatic Breast Cancer, ENDORSE Trial (NCT07590583) | City of Hope Medical Center | 2026-12-19 |
| Elacestrant With Everolimus for the Treatment of Recurrent Advanced or Metastatic ER-Positive Endometrial Cancer (NCT07634601) | Jonsson Comprehensive Cancer Center | 2026-12-18 |
| 64Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic Cancer (NCT07608627) | City of Hope Medical Center | 2026-12-16 |
| Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody Rituximab for the Treatment of Marginal Zone Lymphoma (NCT07583810) | City of Hope Medical Center | 2026-12-16 |
| Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in Participants With Pulmonary Fibrosis (NCT07441408) | Bristol-Myers Squibb | 2026-12-16 |
| Feasibility of Using NeuraSignal Transcranial Doppler Robot (NCT06565442) | University of Alabama at Birmingham | 2026-12-15 |
| Ultrasound-Guided Platelet-Rich Plasma Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation (NCT07624890) | Ukrainian Society of Regional Anesthesia and Pain Therapy | 2026-12-15 |
| Effects of Therapeutic Touch and Music on Children's Anxiety, Pain, and Nausea Before and After Circumcision (NCT07728266) | Igdir University | 2026-12-15 |
| Effect of a Mobile App for Obese Children on Eating Attitudes, Eating Awareness, and Healthy Eating Self-Efficacy (NCT07289425) | Cumhuriyet University | 2026-12-15 |
| ENA-001 for Post Operative Respiratory Depression (PORD) (NCT06137638) | Enalare Therapeutics Inc. | 2026-12-15 |
| Intertransverse Process Block Versus External Oblique Intercostal Plane Block After Laparoscopic Sleeve Gastrectomy (NCT07591116) | Antalya City Hospital | 2026-12-15 |
| Starlight Therapy in Palliative Care (NCT03716999) | Nova Scotia Health Authority | 2026-12-15 |
| Neuraxial Ultrasound Device Study (NCT06281249) | Stanford University | 2026-12-15 |
| Clinical Evaluation of the Efficacy of a Nasal Spray in the Treatment of Nasal Dryness (NCT07657247) | YSLab | 2026-12-15 |
| BSB-2002 After Cyclophosphamide and Fludarabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With NPM1 Mutation (NCT07583303) | City of Hope Medical Center | 2026-12-14 |
| Effect of Marital Adjustment Strategies on Emotional Divorce Among Married Women (NCT07652411) | Mansoura University | 2026-12-11 |
| A Study of the Efficacy and Safety of FXS6837 Capsules Compared to Eculizumab for 24 Weeks in Patients With PNH. (NCT07747090) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2026-12-10 |
| Training on Systemic and Organ Spec. PM in PC (NCT07768917) | Massachusetts General Hospital | 2026-12-10 |
| Safety and Efficacy of YB-1113 in Treatment of POI (NCT05494723) | Bright Cell, Inc. | 2026-12-09 |
| A Study of TIL in Advanced Solid Tumors (CZ) (NCT07294872) | Shanghai Juncell Therapeutics | 2026-12-08 |
| Calcium Channel Blocker in Myotonic Dystrophy Type 1 (NCT07075965) | University of Rochester | 2026-12-07 |
| Treatment Education for Perinatal Women and Their Community Support (NCT06733649) | Johns Hopkins University | 2026-12-06 |
| Changes in Spatiotemporal Gait Parameters During a Digitally Assisted Self-rehabilitation Program for Elderly Fallers ( DigiWalk ) (NCT07741994) | University Hospital, Angers | 2026-12-05 |
| Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin Lymphoma (NCT07572123) | National Cancer Institute (NCI) | 2026-12-04 |
| A Prospective, Multi-centre, Single Arm, Pivotal Clinical Study to Determine the Safety and Effectiveness of Crea Aortic Valve for Use as a Replacement Aortic Heart Valve (NCT07734025) | Onecrea Medical Inc. | 2026-12-04 |
| Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma (NCT07422363) | National Cancer Institute (NCI) | 2026-12-04 |
| Testing Short-Course Radiation Versus Standard-Course Radiation for Soft Tissue Sarcomas That Need Surgery and Radiation (NCT07615049) | SWOG Cancer Research Network | 2026-12-02 |
| Rituximab With Corticosteroids Versus Corticosteroids Plus Azathioprine for Moderate-to-Severe Pemphigus Vulgaris (NCT07769333) | Khyber Teaching Hospital | 2026-12-02 |
| A Web-Based Text Messaging for Tobacco Cessation in Rural Mississippi (NCT07431619) | University of Mississippi Medical Center | 2026-12-01 |
| Geriatric Assessment-Guided Treatment Selection in Older Adults With Acute Myeloid Leukemia (NCT07735208) | University of Rochester | 2026-12-01 |