| Neoadjuvant HS-10296 (Almonertinib) Therapy for Potential Resectable Stage III EGFR Mutation-Positive Non-small Cell Lung Cancer (NCT04685070) | Shanghai Pulmonary Hospital, Shanghai, China | 2021-12-14 |
| TAME: A Pilot Study of Weekly Paclitaxel, Bevacizumab, and Tumor Associated Macrophage Targeted Therapy (Zoledronic Acid) in Women With Recurrent, Platinum-resistant, Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (NCT05053750) | M.D. Anderson Cancer Center | 2021-12-14 |
| Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens (NCT04821141) | University of Kansas Medical Center | 2021-12-14 |
| A Study to Assess Disease Activity in Adolescent and Adult Participants With Atopic Dermatitis Who Receive Oral Upadacitinib Tablets in a Real-World Setting (NCT05139836) | AbbVie | 2021-12-13 |
| Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2) (NCT05156281) | Novartis Pharmaceuticals | 2021-12-13 |
| SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma. (NCT05022654) | Sichuan Baili Pharmaceutical Co., Ltd. | 2021-12-13 |
| Feasibility and Efficacy of Automated Lateral Decubitus Therapy in Hypoxemic Respiratory Failure (NCT06698913) | University of Sao Paulo General Hospital | 2021-12-13 |
| Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65). (NCT05116189) | Merck Sharp & Dohme LLC | 2021-12-13 |
| Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair (NCT05494073) | Henry Ford Health System | 2021-12-13 |
| A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations (NCT05163028) | HUYABIO International, LLC. | 2021-12-13 |
| Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy (NCT05020912) | Case Comprehensive Cancer Center | 2021-12-13 |
| Evaluating 6-months of HER2-targeted Therapy in Patients With HER2 Positive Early-stage Breast Cancer That Achieve a Pathological Complete Response to Neoadjuvant Systemic Therapy (NCT04928261) | Ottawa Hospital Research Institute | 2021-12-13 |
| BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1) (NCT04982393) | Alnylam Pharmaceuticals | 2021-12-13 |
| Preventing Diabetes in Latino Families (NCT05228522) | Arizona State University | 2021-12-12 |
| Prognostic Role of Circulating Tumor DNA in Resectable Pancreatic Cancer (NCT04246203) | Ludwig-Maximilians - University of Munich | 2021-12-12 |
| Dengue Controlled Human Infection Model in Dhaka, Bangladesh (NCT05229354) | Beth Kirkpatrick | 2021-12-11 |
| Living Green and Healthy for Teens (NCT03996109) | Population Health Research Institute | 2021-12-11 |
| Carbon-13 Magnetic Resonance Spectroscopy in Glycogen Storage Diseases (NCT04929002) | Rigshospitalet, Denmark | 2021-12-10 |
| A Phase 1 Study of Oral OP-1250 in Combination With Palbociclib in HR+/HER2- Breast Cancer Patients (NCT05266105) | Olema Pharmaceuticals, Inc. | 2021-12-10 |
| Safety, Pharmacokinetics and Clinical Activity of AZD0171 in Combination With Durvalumab and Chemotherapy in Locally Advanced or Metastatic Solid Tumours (NCT04999969) | AstraZeneca | 2021-12-10 |
| Optimization of Immunotherapy Treatment for Advanced Melanoma in the Context of the Public Brazilian Health System (OTIMAS) (NCT07376317) | Instituto do Cancer do Estado de São Paulo | 2021-12-10 |
| Non-pharmacological Treatment for Pain After Spine Surgery (NCT04770480) | Dan Rhon | 2021-12-10 |
| RCT, Blinded, 2-Arm Efficacy Study of IP and Placebo in Patients With Chronic Pain Related to Osteoarthritis of the Knee (NCT05318521) | Overseas Pharmaceuticals, Ltd. | 2021-12-10 |
| Building Resiliency in Dyads of Patients With an ANI Admitted to the Neuro-ICU and Their Informal Caregivers (NCT05157880) | Massachusetts General Hospital | 2021-12-10 |
| Atezolizumab in Patients With MSI-h/MMR-D Stage II High Risk and Stage III Colorectal Cancer Ineligible for Oxaliplatin (NCT05118724) | AIO-Studien-gGmbH | 2021-12-10 |
| NTLA-2002 in Adults With Hereditary Angioedema (HAE) (NCT05120830) | Intellia Therapeutics | 2021-12-10 |
| Surufatinib in Patients With Osteosarcoma and Soft Tissue Sarcoma (NCT05106777) | Sun Yat-sen University | 2021-12-10 |
| Prospective Case Collection Study for New Mammography Technologies (NCT05199701) | Hologic, Inc. | 2021-12-10 |
| Concomitant Radiotherapy, Tremelimumab & Durvalumab for Advanced NSCLC Patients Progressing on First-line Immunotherapy (NCT05000710) | Sheba Medical Center | 2021-12-09 |
| NATURE (EnVast as an Adjunct PPCI in Subjects Presenting With STEMI) (NCT04969471) | Vesalio | 2021-12-09 |
| EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke (NCT05029414) | University Hospital, Basel, Switzerland | 2021-12-09 |
| A Study of Stereotactic Body Radiation Therapy (SBRT) Without Androgen Deprivation Therapy (ADT) in People With Unfavorable Intermediate-Risk Prostate Cancer (NCT05169970) | Memorial Sloan Kettering Cancer Center | 2021-12-09 |
| PATHFINDER 2: A Multi-Cancer Early Detection Study (NCT05155605) | GRAIL, Inc. | 2021-12-08 |
| Invest-CTO PCI Trial (NCT04774913) | Haukeland University Hospital | 2021-12-08 |
| CPD-DARA in Patients With Relapsed/Refractory Multiple Myeloma. (NCT04667663) | Cancer Trials Ireland | 2021-12-08 |
| Surveying Patient's Interest in Robotic Rehabilitation Device (NCT05417802) | State University of New York at Buffalo | 2021-12-08 |
| A Study of N-Acetylcysteine (N-AC) in People Receiving CAR T-cell Therapy for Lymphoma (NCT05081479) | Memorial Sloan Kettering Cancer Center | 2021-12-08 |
| A Study of Isatuximab Added to Standard CyBorD Induction and Lenalidomide Maintenance Treatments in ND-TEMM (NCT04786028) | Canadian Myeloma Research Group | 2021-12-08 |
| MInimal Residual Disease Adapted Strategy (NCT04934475) | Intergroupe Francophone du Myelome | 2021-12-08 |
| SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC. (NCT05020457) | Sichuan Baili Pharmaceutical Co., Ltd. | 2021-12-07 |
| PMCF Study of LiquiBand FIX8® OHMF Device (NCT04059640) | Advanced Medical Solutions Ltd. | 2021-12-07 |
| Long-term Efficacy and Safety Study of GV-971 (NCT05181475) | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | 2021-12-07 |
| Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C (NCT03482986) | Brigham and Women's Hospital | 2021-12-07 |
| Bicalutamide Implants (Biolen) With Radiation Therapy in Patients With Localized Prostate Cancer (NCT04943536) | Alessa Therapeutics Inc. | 2021-12-07 |
| Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA) (NCT05002777) | Sanofi | 2021-12-07 |
| NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies (NCT05023486) | Novita Pharmaceuticals, Inc. | 2021-12-07 |
| Vulvovaginal Candidiasis in Canadian Females (NCT04930107) | University of Manitoba | 2021-12-07 |
| Timing Intervention of Morning Versus Evening Exercise (NCT05153252) | University of Colorado, Denver | 2021-12-07 |
| Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases (NCT05034497) | Plus Therapeutics | 2021-12-06 |
| A Trial of SHR1701 Plus Chemotherapy in Patients With Gastric or Gastroesophageal Cancer (NCT04950322) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2021-12-06 |
| Short-term Pre-OPerative Durvalumab (MEDI 4736) in Early Small Triple Negative Breast Cancer Patients (POP-Durva) (NCT05215106) | Gustave Roussy, Cancer Campus, Grand Paris | 2021-12-06 |
| Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer (NCT04821284) | Flemming Forsberg | 2021-12-06 |
| One Day Implantation Program for Heart Failure Patients Implanted With CRT-P (NCT05142293) | Biotronik SE & Co. KG | 2021-12-06 |
| Durvalumab and Low-dose PCI vs Durvalumab and Observation in Radically Treated Patients With Stage III NSCLC (NVALT28) (NCT04597671) | Association NVALT Studies | 2021-12-06 |
| Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial (NCT05050084) | NRG Oncology | 2021-12-06 |
| Bioavailability of Vitamin D(25(OH)D) and Omega-3 Fatty Acid (DHA) Enhanced Chicken (NCT05248737) | Cornell University | 2021-12-04 |
| Long-term Safety and Efficacy Profile of ABX464 in Subjects With Moderate to Severe Active Ulcerative Colitis (NCT05177835) | Abivax S.A. | 2021-12-03 |
| Trial in AML Secondary to MPNs Patients, Unfit for Intensive Chemotherapy, Investigating a Treatment Combination Including Decitabine and Venetoclax (NCT04763928) | Gruppo Italiano Malattie EMatologiche dell'Adulto | 2021-12-03 |
| Observatory of Patients With Haemophilia B Treated by IdElvion® (NCT05086575) | CSL Behring | 2021-12-03 |
| Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers (NCT04633811) | University of Alabama at Birmingham | 2021-12-03 |
| Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial (NCT03496883) | Joseph Broderick, MD | 2021-12-03 |
| Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects (NCT05172726) | Organon and Co | 2021-12-02 |
| Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection (NCT05307835) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2021-12-02 |
| Robotic Exoskeleton Gait Training in Adolescents With Cerebral Palsy (NCT05158218) | Father Flanagan's Boys' Home | 2021-12-02 |
| Estrogen Administration for the Treatment of NASH in Postmenopausal Women (NCT04833140) | Massachusetts General Hospital | 2021-12-02 |
| A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers (NCT05152147) | Jazz Pharmaceuticals | 2021-12-02 |
| Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia (NCT04541212) | Montreal Heart Institute | 2021-12-02 |
| A Study of Amivantamab in People With Esophagogastric Cancer (NCT05117931) | Memorial Sloan Kettering Cancer Center | 2021-12-02 |
| Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery (NCT04391049) | NRG Oncology | 2021-12-02 |
| Echocardiographic Screening of Pregnant Women During Antenatal Care (NCT04936815) | Thomas Pilgrim | 2021-12-01 |
| Pharmaceutical Care and Quality of Life in Conditions Related to Psychotropic Drug Use (NCT06889636) | University of Rijeka | 2021-12-01 |
| Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging (NCT04120766) | Gregory Jicha, MD, PhD | 2021-12-01 |
| Immediate Mobilization Versus 2 Weeks Cast Immobilization After Distal Radius Fracture Treated With Volar Locking Plate (NCT05150925) | Tampere University Hospital | 2021-12-01 |
| Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma (NCT04910022) | Nerviano Medical Sciences | 2021-12-01 |
| Immune and Genomic Markers in ALK+ NSCLC (NCT04881916) | Massachusetts General Hospital | 2021-12-01 |
| Head and Intraocular Trauma Tool for the Identification of Mild Traumatic Brain Injury (NCT05092295) | Rebiscan, Inc. | 2021-12-01 |
| Shortened vs Standard Chemotherapy Combined With Immunotherapy for the Initial Treatment of Patients With High Tumor Burden Follicular Lymphoma (NCT05058404) | Fondazione Italiana Linfomi - ETS | 2021-12-01 |
| Telehealth to Improve Functional Status and Quality of Life in Veterans With PAD (NCT05048979) | VA Office of Research and Development | 2021-12-01 |
| Cardiovascular Risk Reduction-Diet in Pregnancy - Follow up 20 Years After the "CARRDIP"-Trial (NCT05030922) | Per Ole Iversen, MD | 2021-12-01 |
| Gestational Diabetes Monitoring and Management (NCT06963528) | University of Oxford | 2021-12-01 |
| Autoimmune Intervention Mastery Course Study (NCT05057676) | Terry L. Wahls | 2021-12-01 |
| [18F]F-AraG PET Imaging to Visualize Tumor Infiltrating T-cell Activation in Non-small Cell Lung Cancer. (NCT05157659) | Amsterdam UMC, location VUmc | 2021-12-01 |
| Effects of Isolated Lumbar Extension Resistance Training Alone and in Combination with General Exercise and Manual Therapy (NCT06890052) | University of Wuerzburg | 2021-12-01 |
| Eliminating Monitor Overuse Trial (EMO Trial) (NCT05132322) | Children's Hospital of Philadelphia | 2021-12-01 |
| Targeting Inflammation for Endometrial Cancer Prevention (NCT05407025) | Mayo Clinic | 2021-12-01 |
| A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC) (NCT05060016) | Amgen | 2021-12-01 |
| Are Smokers Switching to Vaping at Lower Risk for Cancer? (Electronic Cigarettes and Cancer Risk) (NCT03750825) | University of Southern California | 2021-12-01 |
| The Use of Remote Monitoring for Orthodontic Retention Review (NCT05006339) | Sydney Local Health District | 2021-12-01 |
| Effects of Sulforaphane for Patients With Chronic Kidney Disease (NCT04608903) | Universidade Federal Fluminense | 2021-12-01 |
| A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101) (NCT05245968) | Taiho Pharmaceutical Co., Ltd. | 2021-12-01 |
| Urinary Antigen Test for Stretococcus Pneumoniae Serotype Prevalence in Community Acquired Pneumonia (NCT05374018) | Chinese University of Hong Kong | 2021-12-01 |
| Omega Tots Long Term Follow-up (NCT05191823) | Sarah Keim | 2021-12-01 |
| An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C) (NCT05112965) | Hoffmann-La Roche | 2021-12-01 |
| Early NK Precut vs TPS in Difficult Cannulation: A RCT (ENKPT Trial) (NCT07048977) | Chang Gung Memorial Hospital | 2021-12-01 |
| Long-Chain Fatty Acid Oxidation Disorders In-Clinic Disease Monitoring Program (NCT04632953) | Ultragenyx Pharmaceutical Inc | 2021-11-30 |
| A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT) (NCT04770779) | Agios Pharmaceuticals, Inc. | 2021-11-30 |
| Hydroxychloroquine and Chlorphenesin Carbamate in Combination With mFOLFIRINOX in Pancreatic Cancer (NCT05083780) | Changhoon Yoo | 2021-11-30 |
| Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center? (NCT05167227) | Family Health Centers of San Diego | 2021-11-30 |
| The Study on the Safety and Efficacy of the G-iliac Iliac Bifurcation Stent Graft System (NCT06660927) | Lifetech Scientific (Shenzhen) Co., Ltd. | 2021-11-30 |
| Effect of Low-dose 500 mg Abiraterone Acetate in Treatment of Metastatic Prostate Cancer Patients (NCT06193993) | National University Hospital, Singapore | 2021-11-30 |