| Enhancing the Therapeutic Effect of Bracing for Adolescent Idiopathic Scoliosis With a Hybrid Bracing Protocol (NCT07045337) | Chinese University of Hong Kong | 2022-01-01 |
| Research on Optimizing the Use of Technology With Education (NCT05564481) | Children's National Research Institute | 2022-01-01 |
| FITMI - First In Treating Male Infertility (NCT05212337) | Martin Blomberg Jensen | 2022-01-01 |
| Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain (NCT05103527) | Kenneth B Chapman | 2022-01-01 |
| The Use of Expandeded Mesenchymal Stromal Cells (MSC) in Premature Ovarian Failure (POF) in Adult Humans (NCT04815213) | University of Jordan | 2022-01-01 |
| Study Of Comparing SAF-189s With Crizotinib In First Line ALK-Positive Advanced and Metastatic NSCLC (NCT06569420) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2021-12-31 |
| A Study Comparing Allogeneic Hematopoietic Cell Transplantation Versus Best Available Standard of Care Therapy in Elderly Patients With Acute Myeloid Leukemia (NCT04822766) | Assistance Publique - Hôpitaux de Paris | 2021-12-31 |
| the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial) (NCT05527704) | Medical University of Warsaw | 2021-12-31 |
| HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics (NCT04905082) | City of Hope Medical Center | 2021-12-30 |
| Evaluation of the Safety and Efficacy of Hemophilia B Gene Therapy Drug (NCT05203679) | Shanghai Xinzhi BioMed Co., Ltd. | 2021-12-30 |
| Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading (NCT04514744) | McMaster University | 2021-12-30 |
| Hypofractionation for Prostate Cancer in Africa: A Feasibility Study (NCT06950307) | Muhimbili University of Health and Allied Sciences | 2021-12-30 |
| Spinal Cord Stimulation (SCS) for Spinal Cord Injury (SCI) (NCT04894734) | Nandan Lad, M.D., Ph.D. | 2021-12-30 |
| Thoracostomy Tube Irrigation: a Multi-Center Trial (NCT05935267) | Methodist Health System | 2021-12-30 |
| Resistance to the Tyrosine Kinase Inhibitor Osimertinib and Pharmacokinetics in Non-small Cell Lung Cancer (NCT05020275) | Rennes University Hospital | 2021-12-29 |
| Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study) (NCT04947319) | Ono Pharmaceutical Co., Ltd. | 2021-12-29 |
| A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies (NCT05199272) | 23andMe, Inc. | 2021-12-29 |
| Early Phase Clinical Trial About Therapeutic Biological Product Mix for Treating CEA Positive Rectal Cancer (NCT02403505) | Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair | 2021-12-28 |
| A Phase II Randomized Study of Gemcitabine and Nab-paclitaxel in Combination With S- 1/LV (GASL) or Oxaliplatin (GAP) as First-line Treatment for Metastatic Pancreatic Cancer (NCT05026905) | National Health Research Institutes, Taiwan | 2021-12-28 |
| Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology-3 Trial (NCT05171569) | Population Health Research Institute | 2021-12-28 |
| HBM4003 Combine With Toripalimab in Patients With Advanced NEN and Other Solid Tumors Study (NCT05167071) | Harbour BioMed (Guangzhou) Co. Ltd. | 2021-12-28 |
| A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults (NCT05164094) | ModernaTX, Inc. | 2021-12-28 |
| Carfilzomib and Belatacept for Desensitization (NCT05017545) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-12-28 |
| Lorlatinib Continuation Study (NCT05144997) | Pfizer | 2021-12-28 |
| A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy (NCT05139602) | AbbVie | 2021-12-28 |
| Developing mHealth to Promote PrEP Use Among Thai Young Vulnerable Adolescents and Emerging Adults (NCT05262426) | University of Massachusetts, Worcester | 2021-12-27 |
| Crizotinib Continuation Clinical Study (NCT05160922) | Pfizer | 2021-12-27 |
| Program of Angiotensin-Neprilysin Inhibition in Admitted Patients With Worsening Heart Failure (PREMIER) (NCT05164653) | Saga University | 2021-12-27 |
| Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma (NCT05108428) | H. Lee Moffitt Cancer Center and Research Institute | 2021-12-23 |
| A Study of Pembrolizumab With Lenvatinib in Women With Advanced Uterine Carcinosarcoma (NCT05147558) | Memorial Sloan Kettering Cancer Center | 2021-12-23 |
| Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study (NCT04685590) | Washington University School of Medicine | 2021-12-22 |
| Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) (NCT05269394) | Washington University School of Medicine | 2021-12-22 |
| ACL Reconstruction with a New Generation of LARS Artificial Ligament (NCT06571955) | MOVMEDIX | 2021-12-22 |
| The HOME Program for Individuals With Traumatic Brain Injury and Family Members (NCT05117619) | Villanova University | 2021-12-22 |
| A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease (NCT05132166) | University Health Network, Toronto | 2021-12-22 |
| Rho Kinase Inhibitor in Amyotrophic Lateral Sclerosis (REAL) (NCT05218668) | Woolsey Pharmaceuticals | 2021-12-22 |
| Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors (NCT05071209) | National Cancer Institute (NCI) | 2021-12-22 |
| HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome (NCT05127226) | Ionis Pharmaceuticals, Inc. | 2021-12-22 |
| A Clinical Study of SI-B001 in Combination With Paclitaxel in the Treatment of Recurrent and Metastatic HNSCC (NCT05054439) | Sichuan Baili Pharmaceutical Co., Ltd. | 2021-12-22 |
| Assessing Durable Antibody Response to HPV Vaccination (NCT05031078) | Emory University | 2021-12-21 |
| SAPHNELO Systemic Lupus Erythematosus Japan Post-Marketing Surveillance (PMS) (NCT05141201) | AstraZeneca | 2021-12-21 |
| Targeted Alpha-emitter Therapy of PRRT Naïve and Previous PRRT Neuroendocrine Tumor Patients (NCT05153772) | Orano Med LLC | 2021-12-21 |
| Study of Plinabulin and Pegfilgrastim in People With Multiple Myeloma Undergoing an Autologous Hematopoietic Stem Cell Transplant (AHCT) (NCT05130827) | Memorial Sloan Kettering Cancer Center | 2021-12-21 |
| A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis (NCT05197036) | Smith & Nephew, Inc. | 2021-12-21 |
| Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400. (NCT05145062) | Sangamo Therapeutics | 2021-12-21 |
| Tiragolumab With Atezolizumab Plus Bevacizumab in Previously-Treated Advanced Non-squamous NSCLC (NCT04958811) | Georgetown University | 2021-12-21 |
| Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer (NCT04905069) | Boston Scientific Corporation | 2021-12-21 |
| Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE (NCT04919226) | ITM Solucin GmbH | 2021-12-21 |
| Study of Belantamab Mafodotin in Combination With Kd for the Treatment of Relapsed Myeloma Patients, Refractory to Lenalidomide (NCT05060627) | PETHEMA Foundation | 2021-12-20 |
| A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC) (NCT04819100) | Eli Lilly and Company | 2021-12-20 |
| Epigenome-wide DNA Methylation Profiling in Aneurysmal Subarachnoid Hemorrhage and Delayed Ischemic Neurologic Deficit (NCT06881329) | Pomeranian Medical University Szczecin | 2021-12-20 |
| INSPIRE Pipeline™ Shield Post Approval Study (NCT05071963) | Medtronic Neurovascular Clinical Affairs | 2021-12-20 |
| Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin (NCT04533750) | National Cancer Institute (NCI) | 2021-12-20 |
| Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety (NCT05157386) | Region Stockholm | 2021-12-20 |
| A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT) (NCT04770753) | Agios Pharmaceuticals, Inc. | 2021-12-20 |
| Study of Tafasitamab and Lenalinomide Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older (NCT04974216) | The Lymphoma Academic Research Organisation | 2021-12-20 |
| Study to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PL (NCT05164341) | Chiesi Farmaceutici S.p.A. | 2021-12-17 |
| A Multimodal Parent-focused Intervention for Vulnerable Populations in the Bronx (NCT04991467) | Albert Einstein College of Medicine | 2021-12-17 |
| Treatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer (NCT05041842) | UNICANCER | 2021-12-17 |
| Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-positive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor. (NCT05038735) | Novartis Pharmaceuticals | 2021-12-17 |
| Barriers and Facilitators in Access to OT/PT in Pediatric Cancer Survivors (NCT05305950) | M.D. Anderson Cancer Center | 2021-12-17 |
| Advanced Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants (NCT04701437) | Montefiore Medical Center | 2021-12-17 |
| Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-1) (NCT05147220) | Novartis Pharmaceuticals | 2021-12-16 |
| Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer (NCT04989946) | University of Wisconsin, Madison | 2021-12-16 |
| Monitoring of the Safety and the Performance of the Endoscopic Cap Electrode (ECE50) (NCT05245942) | MED-EL Elektromedizinische Geräte GesmbH | 2021-12-16 |
| Ablation vs Resection of Colorectal Cancer Liver Metastases (NCT05129787) | Oslo University Hospital | 2021-12-16 |
| Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily Maintenance Inhalers (NCT05111262) | Washington University School of Medicine | 2021-12-16 |
| A Pilot Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) in Central Non-Small Cell Lung Cancer (NCT05138900) | Roswell Park Cancer Institute | 2021-12-16 |
| Targeted Alpha Therapy With 225Actinium-Prostate Specific Membrane Antigen (PSMA)-I&T of Castration-resISTant Prostate Cancer (TATCIST). (NCT05219500) | Fusion Pharmaceuticals Inc. | 2021-12-16 |
| Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma (NCT05097287) | Sanofi | 2021-12-16 |
| French eCLIPs™ Efficacy and Safety Investigation (NCT05330897) | Evasc Medical Systems Corp. | 2021-12-16 |
| Prevention to Improve Outcomes After PVI (NCT05148338) | Catharina Ziekenhuis Eindhoven | 2021-12-16 |
| Venetoclax in Addition to Blinatumomab in Adult Patients With Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) (NCT05182385) | Goethe University | 2021-12-15 |
| Treat-to-target by Email During Urate-lowering Therapy in Gout (NCT04733079) | Assistance Publique - Hôpitaux de Paris | 2021-12-15 |
| From the Emergency Department Directly to Ablation of Atrial Fibrillation Study (NCT05294445) | Asklepios proresearch | 2021-12-15 |
| Olaparib, Durvalumab and UV1 in Relapsed Ovarian Cancer (NCT04742075) | Nordic Society of Gynaecological Oncology - Clinical Trials Unit | 2021-12-15 |
| Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse (NCT05063331) | University Hospitals Cleveland Medical Center | 2021-12-15 |
| Study of Pregnancy Outcomes in Women Exposed to Rimegepant During Pregnancy (NCT05198245) | Pfizer | 2021-12-15 |
| Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma (NCT05170334) | H. Lee Moffitt Cancer Center and Research Institute | 2021-12-15 |
| Analgesic and Subjective Effects of Terpenes (NCT04451863) | University of California, Los Angeles | 2021-12-15 |
| Automated Video-Assisted Smoking Treatment for People Living With HIV (NCT05014282) | H. Lee Moffitt Cancer Center and Research Institute | 2021-12-15 |
| Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer (NCT04941287) | National Cancer Institute (NCI) | 2021-12-15 |
| CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer (NCT05210283) | Exact Sciences Corporation | 2021-12-15 |
| Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC. (NCT05615142) | Sichuan University | 2021-12-15 |
| Testing a Novel Data-to-Suppression (D2S) Intervention Strategy in the Ryan White HIV/AIDS Program (NCT05140421) | City University of New York | 2021-12-15 |
| Acalabrutinib and Rituximab in Elderly Patients With Untreated Mantle Cell Lymphoma (NCT05214183) | Nordic Lymphoma Group | 2021-12-15 |
| The DESyne BDS Plus RCT: A Randomized Clinical Trial to Assess the Elixir DESyne BDS Plus Drug Eluting Coronary Stent System for the Treatment of de Novo Native Coronary Artery Lesions (NCT05033964) | Elixir Medical Corporation | 2021-12-15 |
| Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy (NCT05167721) | Mayo Clinic | 2021-12-15 |
| Childhood Obesity Management Using Innovative Digital Technology (NCT06777888) | University of Victoria | 2021-12-15 |
| Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System (NCT05155956) | University of Pennsylvania | 2021-12-15 |
| A Multi-center Open-label Phase 2 Study of Ixazomib, Iberdomide and Dexamethasone in Elderly Patients With Multiple Myeloma at First Relapse." (NCT04998786) | Nantes University Hospital | 2021-12-14 |
| Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty (NCT05607303) | University of Colorado, Denver | 2021-12-14 |
| Tadalafil as Adjuvant Therapy for DMD (NCT05195775) | University of Florida | 2021-12-14 |
| RESOLUTE Trial Aims to Investigate the Value of Adding Local Ablative Treatment to Standard Systemic Treatment for Unresectable Oligometastatic Colorectal Cancer (NCT05862051) | Australasian Gastro-Intestinal Trials Group | 2021-12-14 |
| Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma (NCT04019262) | John Flickinger | 2021-12-14 |
| Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients (NCT04337255) | Rush University Medical Center | 2021-12-14 |
| Mobile App for Smoking Cessation and Mental Health (NCT04887558) | University of Oklahoma | 2021-12-14 |
| A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases (NCT05341739) | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 2021-12-14 |
| A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis (NCT05070858) | Regeneron Pharmaceuticals | 2021-12-14 |
| Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure) (NCT04954859) | GlaxoSmithKline | 2021-12-14 |